Family Search for PF12494 (DUF3695)

PF12494 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

CF276_HUMAN / Q5T5A4 Cilia- and flagella-associated protein 276 from Homo sapiens (Human) (see 2 papers)
Aligns to 29:127 / 169 (58.6%), covers 95.0% of PF12494, 142.1 bits

• function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis (PubMed:31199454).

CF276_BOVIN / E1B9I5 Cilia- and flagella-associated protein 276 from Bos taurus (Bovine) (see paper)
Aligns to 29:128 / 170 (58.8%), covers 98.0% of PF12494, 140.3 bits

• function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:34715025). May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis (By similarity).

CF276_MOUSE / Q9DAD0 Cilia- and flagella-associated protein 276 from Mus musculus (Mouse) (see paper)
Aligns to 29:126 / 168 (58.3%), covers 96.0% of PF12494, 121.3 bits

• function: May play an important role for the maintenance of myelin-axon integrity (PubMed:31199454). May affect intracellular Ca(2+) homeostasis.
  function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity). May play an important role for the maintenance of myelin-axon integrity (PubMed:31199454). May affect intracellular Ca(2+) homeostasis (By similarity).

Or search for genetic data about PF12494 in the Fitness Browser