Family Search for PF16043 (DUF4795)

PF16043 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

QRIC2_MOUSE / Q3V2A7 Glutamine-rich protein 2 from Mus musculus (Mouse) (see paper)
Aligns to 97:304 / 592 (35.1%), covers 99.5% of PF16043, 281.9 bits

• function: Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility.
  subunit: Interacts with AKAP3, ODF2 and TSSK4. Interacts with AKAP4.
  disruption phenotype: Knockout mice show coiled, bent, irregular, short or absent flagella, defects of sperm flagellar ultrastructure, a significant reduction in sperm locomotion, and decreased sperm count.

QRIC2_HUMAN / Q9H0J4 Glutamine-rich protein 2 from Homo sapiens (Human) (see 3 papers)
Aligns to 1252:1459 / 1663 (12.5%), covers 99.5% of PF16043, 277.4 bits

• function: Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility.
  subunit: Interacts with AKAP3, ODF2 and TSSK4 (PubMed:30683861). Interacts with AKAP4 (PubMed:34415320).

Or search for genetic data about PF16043 in the Fitness Browser