Family Search for PF00697 (PRAI)

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PF00697 hits 96 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TrpC / b1262 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
trpC / P00909 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli (strain K12) (see 16 papers)
P00909 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Escherichia coli (see 2 papers)
Aligns to 258:449 / 453 (42.4%), covers 99.5% of PF00697, 223.3 bits

TRPF_YEAST / P00912 N-(5'-phosphoribosyl)anthranilate isomerase; PRAI; EC 5.3.1.24 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
Aligns to 24:221 / 224 (88.4%), covers 99.5% of PF00697, 216.3 bits

• catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)

A0A0H4BJU5 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Saccharomycopsis fibuligera (see paper)
Aligns to 68:246 / 252 (71.0%), covers 85.0% of PF00697, 160.2 bits

trpF / Q56320 phosphoribosylanthranilate isomerase subunit (EC 5.3.1.24) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Aligns to 4:201 / 205 (96.6%), covers 100.0% of PF00697, 157.2 bits

P24920 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Phytophthora parasitica (see paper)
Aligns to 330:513 / 531 (34.7%), covers 80.3% of PF00697, 143.3 bits

PAI2_ARATH / Q42527 N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 68:269 / 275 (73.5%), covers 99.5% of PF00697, 132.0 bits

• catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)

PAI1_ARATH / Q42440 N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 68:269 / 275 (73.5%), covers 99.5% of PF00697, 131.4 bits

• function: Catalyzes the conversion of 5-phosphoribosylanthranilate to l-(O-carboxyphenylamino)-l-deoxyribulose-5-phosphate, which is the third step of the tryptophan biosynthetic pathway.
  catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)
  disruption phenotype: Bushy morphology, reduced fertility, blue fluorescence under UV light and resistance to the anthranilate analog 6-methylanthranilate.

BT0528 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Bacteroides thetaiotaomicron VPI-5482
Aligns to 7:204 / 207 (95.7%), covers 99.0% of PF00697, 116.4 bits

• mutant phenotype: Important for fitness in most defined media and strongly cofit with anthranilate phosphoribosyltransferase (BT0530). 37% identical to phosphoribosylanthranilate isomerase from Thermotoga maritima (Q56320)

trpF / B0B7P4 phosphoribosylanthranilate isomerase (EC 5.3.1.24; EC 4.2.1.160) from Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) (see paper)
B0B7P4 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase (EC 4.2.1.160); phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Chlamydia trachomatis (see paper)
Aligns to 3:199 / 208 (94.7%), covers 99.0% of PF00697, 113.7 bits

Q8U092 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Pyrococcus furiosus (see paper)
Aligns to 3:202 / 208 (96.2%), covers 99.5% of PF00697, 107.1 bits

Or search for genetic data about PF00697 in the Fitness Browser