Family Search for PF01458 (SUFBD)

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PF01458 hits 194 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

YnhE / b1683 Fe-S cluster scaffold complex subunit SufB from Escherichia coli K-12 substr. MG1655 (see 22 papers)
SUFB_ECOLI / P77522 Iron-sulfur cluster assembly protein SufB from Escherichia coli (strain K12) (see 2 papers)
Aligns to 233:466 / 495 (47.3%), covers 99.5% of PF01458, 242.2 bits

• function: The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation.
  subunit: Part of the SufBCD complex that contains SufB, SufC and SufD (PubMed:12941942). Interacts with SufA (PubMed:19810706).

AB8I_ARATH / Q9ZS97 Iron-sulfur cluster assembly SufBD family protein ABCI8, chloroplastic; ABC transporter I family member 8; ABC transporter ABCI.8; AtABCI8; Non-intrinsic ABC protein 1; Protein ABC1; Plastid sufB-like protein; Protein LONG AFTER FAR-RED 6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 294:528 / 557 (42.2%), covers 99.5% of PF01458, 237.6 bits

• function: Involved in light signaling, probably by mediating the transport and correct distribution of protoporphyrin IX, a chlorophyll precursor, in response to far-red light.
  disruption phenotype: Plant have an enhanced hypocotyl elongation in far-red light, and accumulates protoporphyrin IX.

YnhC / b1681 Fe-S cluster scaffold complex subunit SufD from Escherichia coli K-12 substr. MG1655 (see 19 papers)
SUFD_ECOLI / P77689 Iron-sulfur cluster assembly protein SufD from Escherichia coli (strain K12) (see 3 papers)
Aligns to 168:393 / 423 (53.4%), covers 99.1% of PF01458, 236.8 bits

• function: The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation. Required for the stability of the FhuF protein.
  subunit: Part of the SufBCD complex that contains SufB, SufC and SufD. Can form homodimers.

AB7I_ARATH / Q9LQK7 Protein ABCI7, chloroplastic; ABC transporter I family member 7; ABC transporter ABCI.7; AtABCI7; Non-intrinsic ABC protein 6; Plastid SufD-like protein from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 223:450 / 475 (48.0%), covers 99.5% of PF01458, 210.4 bits

• subunit: Interacts with NAP7.

SUFB_PLAF7 / Q25799 Iron-sulfur cluster assembly protein SufB; PfSufB from Plasmodium falciparum (isolate 3D7) (see 2 papers)
Aligns to 208:441 / 470 (49.8%), covers 100.0% of PF01458, 171.8 bits

• function: Participates in the sulfur mobilization (SUF) pathway for iron-sulfur (Fe-S) cluster biogenesis (PubMed:28695709). As part of a complex consisting of SufB-SufC(2)-SufD, involved in assembly of [4Fe- 4S] clusters (PubMed:28695709). Exhibits ATPase activity (PubMed:21722645).
  subunit: Component of a complex composed of SufB, SufC and SufD in a stoichiometric ratio of 1:2:1 (PubMed:28695709). Interacts with SufC (PubMed:21722645). Interacts with SufD (PubMed:28695709).

SUFD_PLAF7 / Q8IIW9 Iron-sulfur cluster assembly protein SufD; PfSufD from Plasmodium falciparum (isolate 3D7) (see 2 papers)
Aligns to 1203:1429 / 1462 (15.5%), covers 99.1% of PF01458, 160.4 bits

• function: Participates in the sulfur mobilization (SUF) pathway for iron-sulfur (Fe-S) cluster biogenesis (PubMed:28695709). As part of a complex consisting of SufB-SufC(2)-SufD, involved in assembly of [4Fe- 4S] clusters (PubMed:28695709). Enhances the ATPase activity of SufC (PubMed:28695709).
  subunit: Component of a complex composed of SufB, SufC and SufD in a stoichiometric ratio of 1:2:1 (PubMed:28695709). Interacts with SufB (PubMed:28695709). Interacts with SufC; the interaction enhances the ATPase activity of SufC (PubMed:28695709).
  disruption phenotype: Parasites require exogenously provided mevalonate for survival (PubMed:37166116). No significant effects on apicoplast morphology (PubMed:37166116).

SUFD_PLABA / A0A509AQJ1 Iron-sulfur cluster assembly protein SufD from Plasmodium berghei (strain Anka) (see paper)
Aligns to 1073:1299 / 1340 (16.9%), covers 99.1% of PF01458, 155.4 bits

• function: Participates in the sulfur mobilization (SUF) pathway for iron-sulfur (Fe-S) cluster biogenesis. As part of a complex consisting of SufB-SufC(2)-SufD, involved in assembly of [4Fe-4S] clusters. Enhances the ATPase activity of SufC.
  subunit: Component of a complex composed of SufB, SufC and SufD in a stoichiometric ratio of 1:2:1. Interacts with SufB. Interacts with SufC; the interaction enhances the ATPase activity of SufC.
  disruption phenotype: Repeated attempts to isolate gene deletion mutant failed, suggesting an essential role of the gene during asexual blood stage growth.

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