Family Search for PF01982 (CTP-dep_RFKase)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF01982 hits 16 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

A0A0K1E2F9 CTP-dependent riboflavin kinase (EC 2.7.1.161) from Pyrobaculum sp. WP30 (see paper)
Aligns to 88:208 / 210 (57.6%), covers 100.0% of PF01982, 154.5 bits

Q9HJA6 CTP-dependent riboflavin kinase (EC 2.7.1.161) from Thermoplasma acidophilum (see paper)
Aligns to 99:218 / 220 (54.5%), covers 100.0% of PF01982, 149.6 bits

H2C8H2 CTP-dependent riboflavin kinase (EC 2.7.1.161) from Metallosphaera yellowstonensis (see paper)
Aligns to 93:215 / 217 (56.7%), covers 99.2% of PF01982, 136.3 bits

rfk / Q60365 CTP-dependent riboflavin kinase (EC 2.7.1.161) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
RIFK_METJA / Q60365 Riboflavin kinase; RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase; EC 2.7.1.161 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q60365 CTP-dependent riboflavin kinase (EC 2.7.1.161) from Methanocaldococcus jannaschii (see 3 papers)
Aligns to 7:126 / 132 (90.9%), covers 99.2% of PF01982, 129.5 bits

• function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).
  catalytic activity: CTP + riboflavin = CDP + FMN + H(+) (RHEA:25021)
  cofactor: Mg(2+) (Binds 1 magnesium ion per subunit.) This ion is coordinated by a threonine and an asparagine, and by the alpha- and beta-phosphates of CDP
  subunit: Monomer.

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