Family Search for PF02153 (PDH_N)
PF02153 hits 106 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
BSU22610 prephenate dehydrogenase from Bacillus subtilis subsp. subtilis str. 168
Aligns to 20:176 / 371 (42.3%), covers 99.4% of PF02153, 190.8 bits
- The Blueprint of a Minimal Cell: MiniBacillus
Reuß, Microbiology and molecular biology reviews : MMBR 2016 - “...S. mutans Listeria innocua aroH tyrA Asn asnB BSU22690 BSU22610 No No 1.3.1.12 1COM 3DZB B. subtilis Streptococcus thermophilus BSU30540 No 6.3.5.4 1CT9 E. coli...”
TYRC_ZYMMO / Q04983 Cyclohexadienyl dehydrogenase; Arogenate dehydrogenase; ADH; Prephenate dehydrogenase; PDH; EC 1.3.1.43; EC 1.3.1.12 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
ZMO0420 Arogenate dehydrogenase from Zymomonas mobilis subsp. mobilis ZM4
Aligns to 19:173 / 293 (52.9%), covers 98.7% of PF02153, 189.7 bits
- function: Can function as either prephenate dehydrogenase or as arogenate dehydrogenase in the biosynthesis of L-tyrosine. Catalyzes two analogous reactions: converts prephenate to 4-hydroxyphenylpyruvate and transforms L-arogenate to L-tyrosine. Is not able to utilize NADP(+) instead of NAD(+) as cosubstrate.
catalytic activity: L-arogenate + NAD(+) = CO2 + L-tyrosine + NADH (RHEA:12256)
catalytic activity: NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (RHEA:13869)
subunit: Homodimer. - Model-driven analysis of mutant fitness experiments improves genome-scale metabolic models of Zymomonas mobilis ZM4
Ong, PLoS computational biology 2020 - “...Calculator [ 50 ] to have a similar translation rate as ZMO1503. The ZMO0421 and ZMO0420 genes in pRL814_ZMO0421_ZMO0420 were amplified from the genome with their natural spacing and sequences conserved. All plasmid inserts were confirmed via sequencing. Plasmids used in this work and primers used...”
- “...additional data file. S6 Fig Overview of ZMO0421::Tn5 analysis. (A) Genomic region containing ZMO0421 and ZMO0420, which are in a single operon. (B) Partial pathways for tyrosine and histidine biosynthesis, showing the steps catalyzed by ZMO0421 and ZMO0420. (C) Summary of growth phenotypes of a aspC...”
- Proteomic and metabolomic analysis of the cellular biomarkers related to inhibitors tolerance in Zymomonas mobilis ZM4
Chang, Biotechnology for biofuels 2018 - “...tyrosine, too. Besides, tyrosine can also be formed from l -arogenate by the catalyzation of ZMO0420. Thus, the down-regulation of ZMO0937 and ZMO0420 can lead to a decrease of phenylalanine and tyrosine, which was verified by our results of groups FA, AA, F, and H (Table...”
3gggD / O67636 The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
Aligns to 28:182 / 293 (52.9%), covers 99.4% of PF02153, 189.2 bits
- Ligands: nicotinamide-adenine-dinucleotide; tyrosine (3gggD)
O67636 prephenate dehydrogenase (EC 1.3.1.12) from Aquifex aeolicus (see paper)
Aligns to 45:199 / 311 (49.8%), covers 99.4% of PF02153, 189.0 bits
HP1380 prephenate dehydrogenase (tyrA) from Helicobacter pylori 26695
O25931 Prephenate dehydrogenase (TyrA) from Helicobacter pylori (strain ATCC 700392 / 26695)
Aligns to 5:155 / 265 (57.0%), covers 99.4% of PF02153, 179.9 bits
tyrAa / P73906 arogenate dehydrogenase monomer (EC 1.3.1.78) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P73906 arogenate dehydrogenase (NADP+) (EC 1.3.1.78) from Synechocystis sp. PCC 6803 (see paper)
2f1kA / P73906 Crystal structure of synechocystis arogenate dehydrogenase (see paper)
slr2081 prephenate dehydrogenase from Synechocystis sp. PCC 6803
Aligns to 15:164 / 279 (53.8%), covers 99.4% of PF02153, 179.7 bits
D3S601 Prephenate dehydrogenase from Methanocaldococcus sp. (strain FS406-22)
Aligns to 21:166 / 446 (32.7%), covers 100.0% of PF02153, 157.7 bits
5uyyA / Q81P63 Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
Aligns to 24:179 / 373 (41.8%), covers 99.4% of PF02153, 147.6 bits
Q81P63 prephenate dehydrogenase (EC 1.3.1.12) from Bacillus anthracis (see paper)
Aligns to 29:184 / 378 (41.3%), covers 99.4% of PF02153, 147.5 bits
SCO3221 prephenate dehydrogenase from Streptomyces coelicolor A3(2)
Aligns to 16:161 / 284 (51.4%), covers 99.4% of PF02153, 146.4 bits
- Cytosolic copper is a major modulator of germination, development and secondary metabolism in Streptomyces coelicolor
González-Quiñónez, Scientific reports 2019 - “...0.4 SCO2782 Desferrioxamine biosynthesis 0.6 1.4 0.7 2.7 SCO3218 CDA biosynthesis 1.8 1 3.6 0.5 SCO3221 CDA biosynthesis 1.4 1.2 2.7 2.3 SCO5223 Albaflavenone biosynthesis 0.5 0.6 0.7 1.5 SCO5799 Siderophore biosynthesis 0.9 1 0.6 0.5 SCO6766 Hopene biosynthesis 0.6 0.8 1.5 0.6 SCO6768 1.4 1.1...”
- Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor
Alam, BMC genomics 2010 - “...--0.66 SCO3246 pentadecanoyl-[acyl-carrier protein] synthesis fatty acid biosynthesis --0.63 SCO3595 D-alanine-D-alanine ligase D-alanine metabolism --0.63 SCO3221 prephenate dehydrogenase tryptophan biosynthesis --0.63 SCO6655 GTP cyclohydrolase II riboflavin metabolism --0.61 SCO6787 butyryl-CoA dehydrogenase propanoate metabolism --0.59 SCO2687 GTP cyclohydrolase II riboflavin metabolism --0.52 The most strongly anticorrelated genes...”
- “...of the calcium dependent antibiotics (CDA) biosynthesis gene cluster (SCO3210-SCO3249) [ 17 ]. SCO3210 and SCO3221 are annotated as 2-dehydro-3-deoxyheptonate aldolase and prephenate dehydrogenase respectively, part of the shikimate pathway (tryptophan biosynthesis). Tryptophan is a precursor for CDA, and there are four anticorrelated genes (SCO3211-3214) which...”
BC2939 Arogenate dehydrogenase from Bacillus cereus ATCC 14579
Aligns to 17:172 / 366 (42.6%), covers 99.4% of PF02153, 145.6 bits
Pfl01_4074 bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase from Pseudomonas fluorescens Pf0-1
Aligns to 17:173 / 735 (21.4%), covers 98.7% of PF02153, 137.2 bits
4wjiA / Q92MG1 Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
Aligns to 19:174 / 293 (53.2%), covers 98.1% of PF02153, 133.9 bits
- Ligands: nadp nicotinamide-adenine-dinucleotide phosphate; tyrosine (4wjiA)
PSF113_1640 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase from Pseudomonas ogarae
Aligns to 17:173 / 735 (21.4%), covers 98.7% of PF02153, 133.7 bits
ELZ14_08510, PSEBR_a1552 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase from Pseudomonas brassicacearum
Aligns to 17:173 / 735 (21.4%), covers 98.7% of PF02153, 133.3 bits
AM1_2942 prephenate dehydrogenase tyrA from Acaryochloris marina MBIC11017
Aligns to 15:164 / 278 (54.0%), covers 94.8% of PF02153, 132.1 bits
EF1565 prephenate dehydrogenase from Enterococcus faecalis V583
H7C6X1 Prephenate dehydrogenase from Enterococcus faecalis (strain ATCC 700802 / V583)
Aligns to 17:170 / 364 (42.3%), covers 99.4% of PF02153, 131.6 bits
- Transcriptome, proteome, and metabolite analyses of a lactate dehydrogenase-negative mutant of Enterococcus faecalis V583
Mehmeti, Applied and environmental microbiology 2011 - “...were found to be downregulated significantly (EF1562, EF1564, EF1565, and EF1566). Among the three plasmids of the V583 strain, only pTEF2 carries genes that...”
- Comparison of OG1RF and an isogenic fsrB deletion mutant by transcriptional analysis: the Fsr system of Enterococcus faecalis is more than the activator of gelatinase and serine protease
Bourgogne, Journal of bacteriology 2006 - “...tryptophan biosynthesis EF1561 EF1562 EF1563 EF1564 EF1565 EF1566 EF1567 EF1568 EF1569 aroE P-2-dehydro-3-deoxyheptonate aldolas aroB aroC Prephenate...”
- Transcriptional response of Enterococcus faecalis V583 to erythromycin
Aakra, Antimicrobial agents and chemotherapy 2005 - “...Cell envelope Cell envelope Cell envelope Cell envelope Cell envelope EF0290 EF1565 EF2586 0.71 0.71 0 0 0 0.87 0 0 0.86 0 0 0 1.05 0 0 EF0849 EF0860 EF0887...”
- Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion
Downes, Scientific reports 2023 - “...Q831B4 6-aminohexanoate-cyclic-dimer hydrolase, putative Absent N/A 10 19.1 Q836S5 Prephenate dehydrogenase Absent N/A 7 23.4 H7C6X1 Mga domain-containing protein Absent N/A 6 15.6 Q82ZN7 Protease synthase and sporulation negative regulatory protein pai 1 Absent N/A 2 11.7 Q82ZP9 Transcriptional antiterminator, bglG family Absent N/A 3 7...”
MMP1514 Prephenate dehydrogenase from Methanococcus maripaludis S2
Aligns to 16:161 / 440 (33.2%), covers 100.0% of PF02153, 130.6 bits
PA14_23310 EPSP synthase/prephenate dehydrogenase from Pseudomonas aeruginosa UCBPP-PA14
Aligns to 29:185 / 746 (21.0%), covers 98.7% of PF02153, 130.5 bits
IUJ47_RS10455 prephenate dehydrogenase from Enterococcus faecalis
Aligns to 17:170 / 364 (42.3%), covers 99.4% of PF02153, 130.5 bits
- Antibacterial Components and Modes of the Methanol-Phase Extract from Commelina communis Linn
Liu, Plants (Basel, Switzerland) 2023 - “...3-dehydroquinate dehydratase ( IUJ47_RS11275 ), a 3-dehydroquinate synthase ( IUJ47_RS10445 ), a prephenate dehydrogenase ( IUJ47_RS10455 ), a 3-phosphoshikimate 1-carboxyvinyltransferase ( IUJ47_RS10460 ), a shikimate kinase ( IUJ47_RS10465 ), a chorismate synthase ( IUJ47_RS10450 ), and a prephenate dehydratase ( IUJ47_RS10470 ). Notably, nine DEGs in...”
- “...IUJ47_RS10440 0.066 3-deoxy-7-phosphoheptulonate synthase biosynthesis IUJ47_RS11275 0.151 Type I 3-dehydroquinate dehydratase IUJ47_RS10445 0.154 3-dehydroquinate synthase IUJ47_RS10455 0.227 Prephenate dehydrogenase IUJ47_RS10460 0.262 3-phosphoshikimate 1-carboxyvinyltransferase IUJ47_RS10465 0.278 Shikimate kinase IUJ47_RS10450 0.3 Chorismate synthase IUJ47_RS10470 0.304 Prephenate dehydratase Carbon fixation IUJ47_RS00315 0.096 Flavocytochrome c pathways in prokaryotes IUJ47_RS01530 0.109...”
PA3164 still frameshift 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE prephenate dehydrogenase from Pseudomonas aeruginosa PAO1
Aligns to 29:185 / 746 (21.0%), covers 98.7% of PF02153, 129.5 bits
- Reconciling high-throughput gene essentiality data with metabolic network reconstructions
Blazier, PLoS computational biology 2019 - “...PA2964 pabC 4-Amino-4-deoxychorismate lyase Cofactors and Vitamins PA2969 plsX Fatty acid biosynthesis protein PlsX Lipid PA3164 Frameshift 3-phosphoshikimate-carboxyvinyltransferase prephenate dehydrogenase Amino Acid PA3296 phoA Alkaline phosphatase Cofactors and Vitamins PA3333 fabH2 3-Oxoacyl-[acyl-carrier-protein] synthase III Lipid PA3633 ygbP 4-Diphosphocytidyl-2-C-methylerythritol synthase Lipid PA3659 dapC Succinyldiaminopimelate transaminase Amino Acid...”
- Pseudomonas aeruginosa serA Gene Is Required for Bacterial Translocation through Caco-2 Cell Monolayers
Yasuda, PloS one 2017 - “...1 PA3818 extragenic suppressor protein SuhB suhB NP_252507.1 1 PA0316 D-3-phosphoglycerate dehydrogenase serA NP_249007.1 1 PA3164 still frameshift 3-phosphoshikimate 1-carboxyvinyltransferase aroA AE_004091.2 2 PA3763 phosphoribosylformylglycinamidine synthase purL NP_252452.1 1 PA5015 pyruvate dehydrogenase aceE NP_253702.1 3 PA0413 component of chemotactic signal transduction system chpA NP_249104.1 2 PA3115...”
- Dissection of the cis-2-decenoic acid signaling network in Pseudomonas aeruginosa using microarray technique
Rahmani-Badi, Frontiers in microbiology 2015 - “...nadBE, dapB, trpE, aotJ, phhA, phaF, PA0006, PA0400, PA0440, PA0530, PA1339-PA1342, PA1638, PA2084, PA2108, PA2740, PA3164, PA3271, PA3538, PA3589, PA3871, PA4180, PA4672, PA4774, PA4977, PA5093, PA5522 Amino acid and Fatty acid metabolism gcdH Carbohydrate transport and metabolism rpe, eno, ppsA, tpiA, pykF, pgm, chiC, PA3430 Nucleotide...”
- Pseudomonas aeruginosa Genome Evolution in Patients and under the Hospital Environment
Lucchetti-Miganeh, Pathogens (Basel, Switzerland) 2014 - “...contains a right handed beta helix region that shares some similarity with pectate lyases. The PA3164 gene which in PAO1 strain seems to be a pseudogene due to frameshift is probably encoding a functional 3-phosphoshikimate 1-carboxyvinyltransferase prephenate dehydrogenase in both ST395 strains. Other discrete variations were...”
- A systems-level approach for investigating Pseudomonas aeruginosa biofilm formation
Xu, PloS one 2013 - “...21 1 1 PA1681( aroC ) 22 1 1 PA0548( tktA ) 23 1 1 PA3164( pseudogene ) 24 1 1 PA0330( rpiA ) 25 1 1 PA5038( aroB ) 26 2 1 PA4031( ppa ) 27 3 1 PA0904( lysC ) 28 4 1 PA2023(...”
- Regulatory and metabolic networks for the adaptation of Pseudomonas aeruginosa biofilms to urinary tract-like conditions
Tielen, PloS one 2013 - “...can be converted to chorismate in two sequential steps via the phenate dehydrogenase encoded by PA3164 and the chorismate dehydrogenase encoded by PA5184. Again, both genes were found to be induced. Subsequently, chorismate is converted by the anthranilate synthase PhnA to anthranilate, the direct precursor of...”
- A systems biology approach to drug targets in Pseudomonas aeruginosa biofilm
Sigurdsson, PloS one 2012 - “...metabolism UreB (PA4867) ArgB (PA5323) Aromatic amino acids AroC (PA1681), AroK (PA5039) AroB (PA5038), AroA (PA3164), AroE (PA0025) TrpA (PA0035), TrpB (PA0036), PheA (PA3166) Biosynthesis of cofactors, prosthetic groups and carriers, cell wall/ Lipopolysaccharide/ capsule UppS (PA3652) Biotin biosynthesis AccC (PA4848) Branched chain amino acid biosynthesis...”
- Identification of Pseudomonas aeruginosa genes involved in virulence and anaerobic growth
Filiatrault, Infection and immunity 2006 - “...norD PA1850 PA2637 PA2638 PA2639 PA2641 PA2642 PA2644 PA2645 PA2646 PA2648 PA2649 PA3164 1 1 2 2 1 4 2 1 1 5 1 1 PA3912 PA3913 PA3918 PA4049 PA5497 1 1 1 1 2...”
- “...PA2639 PA2641 PA2642 PA2644 PA2645 PA2646 PA2648 PA2649 PA3164 PA3912 PA3913 PA3918 PA4049 PA5497 Gene Descriptionb nirQ norC norB norD Regulatory protein NirQ...”
- More
SXYL_01513 prephenate dehydrogenase from Staphylococcus xylosus
Aligns to 16:172 / 363 (43.3%), covers 99.4% of PF02153, 127.3 bits
B488_11240 prephenate/arogenate dehydrogenase family protein from Liberibacter crescens BT-1
Aligns to 21:176 / 308 (50.6%), covers 98.1% of PF02153, 126.5 bits
T303_04385 prephenate dehydrogenase from Streptococcus thermophilus ASCC 1275
Aligns to 18:175 / 368 (42.9%), covers 99.4% of PF02153, 126.3 bits
- Transcriptomic Insights Into the Growth Phase- and Sugar-Associated Changes in the Exopolysaccharide Production of a High EPS-Producing Streptococcus thermophilus ASCC 1275
Padmanabhan, Frontiers in microbiology 2018 - “...8 . At 5 h, genes involved in phenyl alanine biosynthesis (T303_04365, T303_04370, T303_04375, T303_04380, T303_04385, T303_04400, T303_04405, T303_04410) were found to be significantly upregulated in M17-G, but these genes were downregulated in M17-S and M17-L. Sucrose and lactose supplemented media had higher number of upregulated...”
PP1770 prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase from Pseudomonas putida KT2440
Aligns to 28:184 / 746 (21.0%), covers 98.7% of PF02153, 125.3 bits
- Functional analysis of aromatic biosynthetic pathways in Pseudomonas putida KT2440
Molina-Henares, Microbial biotechnology 2009 - “...(indole3glycerolphosphate synthase), TrpA (tryptophan synthase alphasubunit), TrpB (tryptophan synthase subunit beta), PheA (chorismate mutase/prephenate dehydratase), PP1770 or TyrA (prephenate dehydrogenase, putative/3phosphoshikimate 1carboxyvinyltransferase), TyrB1 (aromaticaminoacid aminotransferase) and PhhA (phenylalanine4hydrolase). Figure 2 Detailed biosynthetic pathway for tryptophan biosynthesis. Details are as in the legend for Fig.1 . This...”
- “...restored by phenylalanine or tyrosine, the miniTn5 was inserted at the 84th codon of ORF PP1770 ( tyrA ). We then tested whether phenylpyruvate or 4hydroxyphenylpyruvate could replace the requirement for phenylalanine or tyrosine in all of the above pheA and tyrA mutants. As expected, all...”
- Transcriptome analysis of a phenol-producing Pseudomonas putida S12 construct: genetic and physiological basis for improved production
Wierckx, Journal of bacteriology 2008 - “...PP0074 (aroE-1), PP3002 (aroE-2), PP1769 (pheA), PP2170, PP1770, PP4490 (phhA), PP1972 (tyrB-1), PP3590 (tyrB-2), and PP4621 (hmgA). Expression profiles of...”
- Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium
Barbe, Nucleic acids research 2004 - “...fusion is also present in P.aeruginosa (PA3164) and P.putida (PP1770) but not in P.syringae in which the ortholog to ACIAD2222 (PSPTO1748) aligns only on the...”
SPD_1207 prephenate dehydrogenase from Streptococcus pneumoniae D39
Aligns to 17:174 / 367 (43.1%), covers 98.7% of PF02153, 124.9 bits
- Therapeutic potential activity of quercetin complexes against Streptococcus pneumoniae
Osman, Scientific reports 2024 - “...involved in peptidoglycan synthesis, nanA (SPD_1499) which encodes neuraminidase A possessing sialidase activity, and sodA (SPD_1207) which encodes superoxide dismutase, an antioxidant defense modulated by NanB. GeneMANIA analyzed functional association data, including protein and genetic interactions, pathway data, co-expression, co-localization and protein domain similarity, to build...”
PSPTO1748 prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase family protein from Pseudomonas syringae pv. tomato str. DC3000
Aligns to 26:182 / 535 (29.3%), covers 98.7% of PF02153, 124.7 bits
Q8DUW0 prephenate dehydrogenase (EC 1.3.1.12) from Streptococcus mutans (see paper)
Aligns to 18:175 / 368 (42.9%), covers 99.4% of PF02153, 120.9 bits
lp_2034 prephenate dehydrogenase from Lactiplantibacillus plantarum WCFS1
lp_2034 prephenate dehydrogenase from Lactobacillus plantarum WCFS1
Aligns to 16:171 / 365 (42.7%), covers 98.1% of PF02153, 120.2 bits
- Molecular Responses of Lactobacilli to Plant Phenolic Compounds: A Comparative Review of the Mechanisms Involved
López, Antioxidants (Basel, Switzerland) 2021 - “...asp2 : alkaline shock protein p -CA + Human small intestine passage [ 92 ] lp_2034 lp_2035 lp_2037 tyrA ; prephenate dehydrogenase aroE ; 3-phosphoshikimate 1-carboxyvinyltransferase aroF ; chorismate synthase p -CA p -CA p -CA + + + Human small intestine passage [ 92 ]...”
- Transcriptional Reprogramming at Genome-Scale of Lactobacillus plantarum WCFS1 in Response to Olive Oil Challenge
Esteban-Torres, Frontiers in microbiology 2017 - “...down-regulated. In addition, other genes related to respiration metabolism such as six genes ( lp_2033, lp_2034, lp_2035, lp_2036, lp_2037, lp_1084 ) involved in the synthesis of chorismate, which is the menaquinone precursor molecule, and two genes involved in the terpenoid backbone biosynthesis which are also required...”
- Identification of prebiotic fructooligosaccharide metabolism in Lactobacillus plantarum WCFS1 through microarrays
Saulnier, Applied and environmental microbiology 2007 - “...biosynthesis lp_0256 lp_0529 lp_1084 lp_1085 lp_1169 lp_2033 lp_2034 lp_2035 lp_2037 lp_2551 lp_2553 lp_2556 lp_2557 lp_2559 lp_2830 lp_3493 lp_3494 Cysteine...”
ACIAD2222 bifunctional protein [Includes: putative prephenate or cyclohexadienyl dehydrogenase; 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) (AroA)] from Acinetobacter sp. ADP1
Aligns to 21:178 / 748 (21.1%), covers 99.4% of PF02153, 118.3 bits
ABUW_1366 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase from Acinetobacter baumannii
Aligns to 21:178 / 748 (21.1%), covers 98.7% of PF02153, 118.0 bits
AB57_2630 hypothetical protein from Acinetobacter baumannii AB0057
A0A090C137 3-phosphoshikimate 1-carboxyvinyltransferase from Acinetobacter baumannii
ABBFA_001168 3-phosphoshikimate 1-carboxyvinyltransferase from Acinetobacter baumannii AB307-0294
Aligns to 29:186 / 756 (20.9%), covers 98.7% of PF02153, 117.9 bits
Tsac_1619 prephenate dehydrogenase/arogenate dehydrogenase family protein from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Aligns to 17:171 / 281 (55.2%), covers 98.1% of PF02153, 117.5 bits
- The redox-sensing protein Rex modulates ethanol production in Thermoanaerobacterium saccharolyticum
Zheng, PloS one 2018 - “...Regulatory protein MarR Misc CTGAAATAATCATTTCAA -86 Tsac_1550 hfsABCD Iron hydrogenases; sporulation protein Energy TTGTTAATAAATTAACTA -78 Tsac_1619 Prephenate dehydrogenase Carb GTGATTTTAAATGATCAA -10 Tsac_1753 3-oxoacyl-(acyl-carrier-protein) reductase Syn TTGATAAACTTTTATCCA -35 Tsac_1856 PHP domain protein Syn TTGTTTTTAGTTTAACAT -33 Tsac_1947 Fimbrial assembly family protein Mem ATGATTCAAAAAAATCAA -186 Tsac_1985 ABC transporter related...”
CC2224 cyclohexadienyl dehydrogenase from Caulobacter crescentus CB15
Aligns to 23:181 / 312 (51.0%), covers 98.1% of PF02153, 115.2 bits
A1S_2276 hypothetical protein from Acinetobacter baumannii ATCC 17978
Aligns to 2:144 / 714 (20.0%), covers 87.7% of PF02153, 114.8 bits
SA1197 prephenate dehydrogenase from Staphylococcus aureus subsp. aureus N315
Aligns to 16:172 / 363 (43.3%), covers 99.4% of PF02153, 112.4 bits
MCR_0888 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase from Moraxella catarrhalis BBH18
Aligns to 36:190 / 767 (20.2%), covers 91.6% of PF02153, 111.7 bits
SAR1378 prephenate dehydrogenase from Staphylococcus aureus subsp. aureus MRSA252
Aligns to 16:172 / 363 (43.3%), covers 99.4% of PF02153, 110.8 bits
SACOL1401 prephenate dehydrogenase from Staphylococcus aureus subsp. aureus COL
SAUSA300_1260 prephenate dehydrogenase from Staphylococcus aureus subsp. aureus USA300_FPR3757
NWMN_1277 prephenate dehydrogenase from Staphylococcus aureus subsp. aureus str. Newman
Aligns to 16:172 / 363 (43.3%), covers 99.4% of PF02153, 110.3 bits
Cj0130 putative prephenate dehydrogenase from Campylobacter jejuni subsp. jejuni NCTC 11168
Aligns to 15:165 / 275 (54.9%), covers 98.7% of PF02153, 109.5 bits
- Active Packaging of Immobilized Zinc Oxide Nanoparticles Controls Campylobacter jejuni in Raw Chicken Meat
Hakeem, Applied and environmental microbiology 2020 (secret) - Rapid identification of novel immunodominant proteins and characterization of a specific linear epitope of Campylobacter jejuni
Hoppe, PloS one 2013 - “...5 cj0920c, 6 cj1380, 7 cj1381, 8 cj0669, 9 cj1624, 10 cj1320, 11 cj1486, 12 cj0130, 13 cj1366, 14 cj0016, 15 cj1575, 16 1576, 17 cj1729, 18 cj0571, 19 cj0926, 20 cj0927, 21 cj0623 and 22 cj1138. The pictures of the two gels as well as...”
- “...length [aa] Size [kDa] Mean Q s.d. [n=25] Cj0016 [P0C634] 7-cyano-7-deazaguanine synthase 224 25.1 0.640.18 Cj0130 [Q0PC07] prephenate dehydrogenase 275 30.9 0.700.19 Cj0476 [Q9PI33] 50S ribosomal Protein L10 159 17.7 0.400.13 Cj0571 [Q0PAU6] Putative transcriptional regulator 290 34.3 0.520.21 Cj0623 [Q0PAP4] Hydrogenase isoenzymes formation protein 247...”
SAOUHSC_01364 prephenate dehydrogenase, putative from Staphylococcus aureus subsp. aureus NCTC 8325
Aligns to 16:172 / 363 (43.3%), covers 99.4% of PF02153, 108.1 bits
NGO1515 putative oxidoreductase from Neisseria gonorrhoeae FA 1090
Aligns to 19:176 / 290 (54.5%), covers 97.4% of PF02153, 107.5 bits
DMB42_RS42860 prephenate dehydrogenase from Nonomuraea sp. WAC 01424
Aligns to 16:162 / 364 (40.4%), covers 98.7% of PF02153, 106.8 bits
- Genomic-Led Discovery of a Novel Glycopeptide Antibiotic by Nonomuraea coxensis DSM 45129
Yushchuk, ACS chemical biology 2021 - “...DMB42_RS42865 (6) (78%) VanY-carboxypeptidase noc28 dbv6 (95.9%) DMB42_RS42855 (8) (92%) response regulator noc29 dbv5 (92.8%) DMB42_RS42860 (7) (85%) prephenate dehydrogenase (Pdh) noc30 a a putative transposase nocRII dbv4 (94.4%) DMB42_RS42700 (38) (85%) StrR-like transcriptional regulator nocRI dbv3 (86.3%) DMB42_RS42695 (39) (70%) LuxR-like transcriptional regulator a Homologue...”
BCAL2953 putative prephenate dehydrogenase from Burkholderia cenocepacia J2315
Aligns to 25:188 / 312 (52.6%), covers 98.7% of PF02153, 104.9 bits
- Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS
Wong, Frontiers in microbiology 2016 - “...are genes involved in the conversion of chorismate to phenylalanine and tyrosine ( pheA , BCAL2953, and BCAL3004) as well as tryptophan ( trpA, trpC, trpD , and trpF ). We suspect that trp mutants may be tryptophan auxotrophs and are unable to grow in a...”
- “...hisE, BCAL1874 Lysine biosynthesis dapF, BCAS0211 Phenylalanine, tyrosine, and tryptophan biosynthesis phhA, aroK, trpC, trpD, BCAL2953, pheA, BCAL3004, aroE, trpF, trpA, BCAS0366 Valine, leucine, and isoleucine biosynthesis ilvA, ilvI, leuD1, leuB, BCAS0025 FIGURE 6 Schematic diagram of KEGG-derived phenylalanine, tyrosine and tryptophan biosynthesis pathways. Boxes indicate...”
AORI_1476 prephenate dehydrogenase from Amycolatopsis keratiniphila
Aligns to 18:164 / 281 (52.3%), covers 99.4% of PF02153, 104.7 bits
- Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis
Xu, BMC genomics 2014 - “...D-alanyl-D-alanine dipeptidase - - AORI_1474 Hypothetical protein - - AORI_1475 vtr Regulator protein lcl|Y16952.3_cdsid_CAG25754.1 83.33 AORI_1476 pdh Prephenate dehydrogenase lcl|Y16952.3_cdsid_CAG25755.1 84.12 AORI_1477 ATP-binding cassette, subfamily B lcl|AJ223999.1_cdsid_CAA11793.1 88.89 AORI_1478 vcmA Non-ribosomal peptide synthetase lcl|AL078635.1_cdsid_CAB45052.1 81.31 AORI_1479 vcmB Non-ribosomal peptide synthetase lcl|AJ223999.1_cdsid_CAA11795.1 82.34 AORI_1480 vcmC Non-ribosomal peptide...”
- “...of three non-protein amino acids were identified in the genome, i.e. , AORI_1492-AORI_1494 for L-Ht, AORI_1476, AORI_1491, AORI_1495-AORI_1496 for L-Hpg, and AORI_1502-AORI_1505 for L-Dpg. Figure 5 Metabolic pathway of vancomycin biosynthesis. Three steps are involved in the biosynthesis of vancomycin, and the related functional genes in...”
3b1fA / Q8DUW0 Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
Aligns to 21:174 / 286 (53.8%), covers 99.4% of PF02153, 104.6 bits
- Ligand: nicotinamide-adenine-dinucleotide (3b1fA)
Echvi_0125 prephenate dehydrogenase from Echinicola vietnamensis DSM 17526
Aligns to 16:167 / 282 (53.9%), covers 96.1% of PF02153, 104.1 bits
- GapMind: Automated Annotation of Amino Acid Biosynthesis
Price, mSystems 2020 - “...some defined media ( Fig.4B ). This bacterium also has a prephenate or arogenate dehydrogenase (Echvi_0125), which is important for growth in some defined media but not others ( Fig.4B ). It is difficult to understand why PAH is important for fitness in defined media unless...”
SCO1761 prephenate dehydrogenase from Streptomyces coelicolor A3(2)
Aligns to 16:163 / 361 (41.0%), covers 97.4% of PF02153, 102.4 bits
- Ms1 RNA Interacts With the RNA Polymerase Core in Streptomyces coelicolor and Was Identified in Majority of Actinobacteria Using a Linguistic Gene Synteny Search
Vaňková, Frontiers in microbiology 2022 - “...are schematically shown for each sRNA. For as1791 and as1761 RNAs, fragments of sco1791 and sco1761 transcripts detected by Northern blotting are also shown in (A,B) . For scr1506, 5 ends was detected by 5 RACE (G,H) . Linguistic Search for Ms1 RNAs in Actinobacteria The...”
- “...the opposite strand, a fragment of the sco1791 (1260 nt) mRNA. Str3 localizes to the sco1761 gene and similarly to Str1, Str3, is also an antisense RNA (130 nt, AS1711, Figure 1B ). Furthermore, we also detected two short transcripts (110 and 80 nt, respectively) from...”
J9XQS6 prephenate dehydrogenase (EC 1.3.1.12) from uncultured bacterium (see paper)
Aligns to 30:156 / 287 (44.3%), covers 74.0% of PF02153, 100.7 bits
CAC0893 Prephenate dehydrogenase from Clostridium acetobutylicum ATCC 824
Aligns to 22:178 / 286 (54.9%), covers 98.1% of PF02153, 99.4 bits
- Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis
Senger, Biotechnology and bioengineering 2008 - “...CAC0939, CAC0938, CAC1369, CAC2727, CAC0937. List 10: CAC3162/CAC3163, CAC3161, CAC3159, CAC3160, CAC3157/CAC3158. List 11: CAC1234, CAC0893, CAC1369/CAC3031/CAC1001/CAC1819/CAC2832. List 12: CAC1234, CAC0217, CAC1369/CAC3031/CAC1001/CAC1819/CAC2832. List 13 (also shown in Fig. 5 ): CAC2391/CAC3020, CAC2388, CAC2389, CAC2390. Figure 5 Proposed pathway of l -glutamate biosynthesis in C. acetobutylicum given:...”
XNR_5061 prephenate dehydrogenase from Streptomyces albidoflavus
Aligns to 16:163 / 361 (41.0%), covers 98.1% of PF02153, 93.7 bits
novF / Q9L9G2 prephenate dehydrogenase (EC 1.3.1.12) from Streptomyces niveus (see paper)
Aligns to 16:163 / 362 (40.9%), covers 97.4% of PF02153, 89.2 bits
A0A101IGG2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Methanothrix harundinacea (see paper)
Aligns to 26:168 / 310 (46.1%), covers 99.4% of PF02153, 87.7 bits
ACPL_8142 prephenate dehydrogenase/arogenate dehydrogenase family protein from Actinoplanes sp. SE50/110
Aligns to 15:162 / 313 (47.3%), covers 98.7% of PF02153, 84.4 bits
BBMN68_274 prephenate dehydrogenase/arogenate dehydrogenase family protein from Bifidobacterium longum subsp. longum BBMN68
Aligns to 17:171 / 355 (43.7%), covers 99.4% of PF02153, 81.8 bits
MM1275 Prephenate dehydrogenase from Methanosarcina mazei Goe1
Aligns to 25:167 / 472 (30.3%), covers 98.7% of PF02153, 81.7 bits
BMA0430 prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase from Burkholderia mallei ATCC 23344
Aligns to 1:108 / 673 (16.0%), covers 66.9% of PF02153, 75.1 bits
TyrAAT1 / Q944B6 arogenate dehydrogenase (EC 1.3.1.78) from Arabidopsis thaliana (see paper)
TYRA1_ARATH / Q944B6 Arogenate dehydrogenase 1, chloroplastic; TYRATC; TyrAAT1; EC 1.3.1.78 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q944B6 arogenate dehydrogenase (NADP+) (EC 1.3.1.78) from Arabidopsis thaliana (see 2 papers)
AT5G34930 arogenate dehydrogenase from Arabidopsis thaliana
2 alignments in 67:528 / 640 (41.7%), covering up to 72.1% of PF02153, 74.3 bits
- function: Involved in the biosynthesis of tyrosine. Has no prephenate dehydrogenase activity.
catalytic activity: L-arogenate + NADP(+) = CO2 + L-tyrosine + NADPH (RHEA:15417) - Densification of Genetic Map and Stable Quantitative Trait Locus Analysis for Amino Acid Content of Seed in Soybean (Glycine max L.)
Li, Plants (Basel, Switzerland) 2024 - “...AT2G39940 GO:0005515 protein binding Glyma.02g256100 AT3G47570 GO:0016301 kinase activity Glyma.02g256200 AT3G47570 GO:0005515 protein binding Glyma.02g260900 AT5G34930 GO:0000166 nucleotide binding Glyma.02g263500 AT2G40280 GO:0005576 extracellular region Glyma.02g263600 AT2G03430 GO:0005886 plasma membrane Glyma.02g263900 AT5G45840 GO:0005515 protein binding Glyma.02g265400 Null PF07172 glycine-rich protein family Glyma.02g265800 Null PF07172 glycine-rich protein family...”
- An Argon-Ion-Induced Pale Green Mutant of Arabidopsis Exhibiting Rapid Disassembly of Mesophyll Chloroplast Grana
Sanjaya, Plants (Basel, Switzerland) 2021 - “...AtMBD2 (At5g35330) and AtMBD12 (At5g35338). Five genes encoded known chloroplast-targeted proteins, namely TYRAAt1 / TyrA1 (At5g34930), encoding arogenate dehydrogenase [ 53 ]; AtCYP28 (At5g35100), encoding thylakoid lumen-localized cyclophilin [ 54 ]; AMK5 (At5g35170), encoding an envelope- and thylakoid-associated adenylate kinase protein [ 55 ]; PTM (At5g35210),...”
- “...(1.0) ECA1 gametogenesis family protein AT5G34908 Signal peptide (1.0) a ECA1 gametogenesis related family protein AT5G34930 Chloroplast stroma TYRAAt1/TyrA1; arogenate dehydrogenase [ 53 , 60 ] AT5G34940 Signal peptide (1.0) ATGUS3/GUS3; glucuronidase 3 [ 61 ] AT5G35067 Other (1.0) hypothetical protein AT5G35069 Other (0.6), Mitochondrion (0.3)...”
- Imbalance of tyrosine by modulating TyrA arogenate dehydrogenases impacts growth and development of Arabidopsis thaliana
de, The Plant journal : for cell and molecular biology 2019 (PubMed) (secret) - Genetic dissection of vitamin E biosynthesis in tomato
Almeida, Journal of experimental botany 2011 - “...(TyrA, EC 1.3.1.78) At1g15710 ( 358) Chloroplast U567861 (1) Chloroplast SL2.31sc03731 C2_At5g34850 7 (0.4 cM) At5g34930 (640) Chloroplast ( Rippert et al., 2009 ) U570951 (2) Chloroplast SL2.31sc03771 T1212 9 (48 cM) Tyrosine aminotransferase (TAT, EC 2.6.1.5) At5g53970 (414) nd U577103(1) nd SL2.31sc05925 C2_At1g53000 10 (7.5...”
- The Biosynthetic Pathways for Shikimate and Aromatic Amino Acids in Arabidopsis thaliana
Tzin, The arabidopsis book 2010 - “...two genes encoding TyrA enzymes were identified: TyrA1 (At5g34930) and TyrA2 (At1g15710) (Rippert and Matringe, 2002b, a; Rippert et al., 2009). A second...”
- “...3 3 PAT TyrA1, ADS1 TyrA2, ADS2 At5g34930 At1g15710 2.6.1.79 1.3.1.43 1.3.1.43 Prephenate Aminotransferase Arogenate Dehydrogenase Arogenate Dehydrogenase PDH...”
- Coordinations between gene modules control the operation of plant amino acid metabolic networks
Less, BMC systems biology 2009 - “...mutase 32 CM1 AT3G29200 257746_at CM2 AT5G10870 250407_at CM3 AT1G69370 260360_at arogenate dehydrogenase 33 AAT1 AT5G34930 255859_at AAT2 AT1G15710 259486_at tyrosine aminotransferase 34 TAT3 d AT2G24850 263539_at TAT AT5G53970 248207_at prephenate dehydratase 35 PD1 AT2G27820 266257_at PD AT1G08250 261758_at PD AT1G11790 262825_at PD AT3G07630 259254_at PD...”
- Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling
Stracke, The Plant journal : for cell and molecular biology 2007 - “...flavanone 3-hydroxylase (TT6) 253195_at At4g35420 94.7 P 32.9 P 2.9 Dihydroflavonol 4-reductase family protein 252215_at At5g34930 21.3 P 7.7 P 2.8 Arogenate dehydrogenase 266851_at At2g26820 24.3 P 8.8 A 2.8 Avirulence-responsive family protein 261773_at At1g76250 28.5 P 10.4 A 2.7 Expressed protein 258241_at At3g27650 52.9 P...”
- “...noteworthy putative PFG target genes are At1g53270 , encoding an ABC transporter family protein, and At5g34930 , encoding an arogenate dehydrogenase. The ABC transporter might be able to facilitate the transport of flavonols across the tonoplast. In the study of Tohge et al. (2005) two transporters...”
- Dynamic evolution at pericentromeres
Hall, Genome research 2006 - “...F-CTTCTTGATTTCCTCCGTCTCC, R-CCTCT TTGGTACGCTGTTAGGC; and At5g34930, F-TCTTCTCCTT CAATACTTACCT, R-TTCCAAACCCGACGACGATACCAAT. BACs identified with the peri-CEN5...”
NP_001331736 arogenate dehydrogenase from Arabidopsis thaliana
2 alignments in 89:550 / 662 (40.3%), covering up to 72.1% of PF02153, 74.1 bits
all0418 chorismate mutase/prephenate dehydrogenase from Nostoc sp. PCC 7120
Aligns to 40:161 / 281 (43.4%), covers 78.6% of PF02153, 70.0 bits
Ddes_0334 Prephenate dehydrogenase from Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
Aligns to 53:180 / 292 (43.8%), covers 72.7% of PF02153, 69.3 bits
- Coordinated response of the Desulfovibrio desulfuricans 27774 transcriptome to nitrate, nitrite and nitric oxide
Cadby, Scientific reports 2017 - “...Glycosyl transferase family 9 1.75 0.00129 Ddes_0333 Major facilitator family membrane transport protein 1.79 0.00336 Ddes_0334 Prephenate dehydrogenase 1.85 0.00164 Ddes_0335 3-phosphoshikimate 1-carboxyvinyltransferase 2.29 4.16e-5 Ddes_0336 Chorismate mutase 2.47 3.53e-6 Ddes_0337 3-dehydroquinate synthase 1.87 0.00292 Ddes_0525 4Fe-4S ferredoxin family 1.94 0.00030 Ddes_0526 Pyridoxamine 5-phosphate oxidase-related FMN-binding...”
- “...0.00303 H Ddes_0289 SAM-binding methylase 2.41 1.59E-06 R Ddes_0290 alaS Alanyl-tRNA synthetase 1.49 0.0132 J Ddes_0334 Prephenate dehydrogenase 1.52 0.0206 E Ddes_0335 3-phosphoshikimate 1-carboxyvinyltransferase 1.35 0.0377 E Ddes_0336 Chorismate mutase 1.56 0.00875 E Ddes_0337 3-dehydroquinate synthase 1.45 0.0119 E Ddes_0338 Fructose-bisphosphate aldolase 1.34 0.0334 G Ddes_0339...”
DIP0245 Putative prephenate dehydrogenase from Corynebacterium diphtheriae NCTC 13129
Aligns to 22:179 / 336 (47.0%), covers 94.8% of PF02153, 69.2 bits
Cp1002_0130 prephenate dehydrogenase from Corynebacterium pseudotuberculosis 1002
Aligns to 22:180 / 337 (47.2%), covers 92.2% of PF02153, 69.0 bits
Ga0059261_2298 prephenate and/or arogenate dehydrogenase (EC 1.3.1.13) from Sphingomonas koreensis DSMZ 15582
Aligns to 16:149 / 249 (53.8%), covers 83.8% of PF02153, 68.8 bits
- mutant phenotype: Important for fitness in defined media. 31% identical to arogenate dehydrogenase from Arabidopsis (Q9LMR3). The substrate could be prephenate (dehydrogenation first) or arogenate (transamination followed by dehydrogenation).
Rv3754 prephenate dehydrogenase from Mycobacterium tuberculosis H37Rv
Aligns to 2:153 / 301 (50.5%), covers 92.2% of PF02153, 68.4 bits
TYRA_MYCTU / O69721 Prephenate dehydrogenase; PDH; EC 1.3.1.12 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
Aligns to 22:175 / 323 (47.7%), covers 92.2% of PF02153, 68.3 bits
- function: Catalyzes the NAD(+)-dependent conversion of prephenate to p- hydroxyphenylpyruvate, with the elimination of carbon dioxide. Is a key regulatory enzyme in tyrosine biosynthesis. Displays no chorismate mutase (CM) activity, in contrast to TyrA from E.coli and some other bacteria, that are bifunctional and possess a CM domain.
catalytic activity: NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (RHEA:13869)
Npun_R1269 prephenate dehydrogenase from Nostoc punctiforme
Aligns to 108:221 / 359 (31.8%), covers 73.4% of PF02153, 63.5 bits
- Biotechnological Production of the Sunscreen Pigment Scytonemin in Cyanobacteria: Progress and Strategy
Gao, Marine drugs 2021 - “...substrates [ 60 , 66 , 67 ]. Except Npun_R1268 (encoding a DSBA oxidoreductase) and Npun_R1269 (encoding a prephenate dehydrogenase), other genes in Module II have at least two homologous genes. The redundancy of the aromatic amino acid biosynthetic genes should be beneficial for providing more...”
- Mutational Studies of Putative Biosynthetic Genes for the Cyanobacterial Sunscreen Scytonemin in Nostoc punctiforme ATCC 29133
Ferreira, Frontiers in microbiology 2016 - “...oxidative deamination of L -tryptophan to provide indole-3 pyruvic acid ( Figure 1A ). TyrA (Npun_R1269), a putative prephenate dehydrogenase, is thought to be responsible for the oxidation of prephenate to p -hydroxyphenylpyruvic acid ( Gao and Garcia-Pichel, 2011 ). Subsequently ScyA (Npun_R1276), a thiamin-dependent enzyme,...”
COO91_00780 bifunctional chorismate mutase/prephenate dehydrogenase from Nostoc flagelliforme CCNUN1
Aligns to 107:222 / 362 (32.0%), covers 73.4% of PF02153, 63.4 bits
E1R5M5 arogenate dehydrogenase [NAD(P)+] (EC 1.3.1.79) from Sediminispirochaeta smaragdinae (see paper)
Aligns to 18:156 / 251 (55.4%), covers 98.7% of PF02153, 62.0 bits
DVU0464 prephenate and/or arogenate dehydrogenase from Desulfovibrio vulgaris Hildenborough JW710
DVU0464 prephenate dehydrogenase from Desulfovibrio vulgaris Hildenborough
Aligns to 20:141 / 255 (47.8%), covers 44.2% of PF02153, 62.0 bits
- mutant phenotype: # important for fitness in defined media, and rescued by added tyrosine. This is the second or third step in tyrosine synthesis from chorismate via prephenate; it is not clear if dehydrogenation or transamination occurs first.
- Response of Desulfovibrio vulgaris to alkaline stress
Stolyar, Journal of bacteriology 2007 - “...DVU0285 DVU0286 DVU0339 DVU0460 DVU0461 DVU0462 DVU0463 DVU0464 DVU0465 DVU0466 DVU0467 DVU0468 DVU0469 DVU0470 DVU0471 DVU0663 DVU0890 DVU1466 DVU1585 DVU1609...”
CU7111_1858 prephenate dehydrogenase from Corynebacterium urealyticum DSM 7111
Aligns to 39:182 / 336 (42.9%), covers 57.8% of PF02153, 58.2 bits
cur_1935 hypothetical protein from Corynebacterium urealyticum DSM 7109
Aligns to 52:195 / 349 (41.3%), covers 57.8% of PF02153, 58.1 bits
TM0344 prephenate dehydrogenase from Thermotoga maritima MSB8
Aligns to 15:153 / 253 (54.9%), covers 97.4% of PF02153, 55.4 bits
A8AAX2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Ignicoccus hospitalis (see 2 papers)
Aligns to 111:252 / 348 (40.8%), covers 67.5% of PF02153, 55.4 bits
Fisuc_2559 Prephenate dehydrogenase from Fibrobacter succinogenes subsp. succinogenes S85
Aligns to 17:180 / 396 (41.4%), covers 85.7% of PF02153, 54.2 bits
- Generation and Characterization of Acid Tolerant Fibrobacter succinogenes S85
Wu, Scientific reports 2017 - “...protein Fisuc_2123 2.3 0.002766 4Fe-4S ferredoxin iron-sulfur binding domain protein Fisuc_2558 1.9 2.99E-15 Chorismate mutase Fisuc_2559 2.0 1.03E-16 Prephenate dehydrogenase Fisuc_2908 2.1 0.000191 (Sulfur transfer protein involved in) thiamine biosynthesis protein ThiS Acid survival for E . coli knockout mutants To date, genetic manipulation tools are...”
FTN_0055 prephenate dehydrogenase from Francisella tularensis subsp. novicida U112
Aligns to 28:141 / 278 (41.0%), covers 64.9% of PF02153, 53.1 bits
- Francisella tularensis metabolism and its relation to virulence
Meibom, Frontiers in microbiology 2010 - “...absent in the Schu S4 strain but present in both LVS (FTL_048) and subsp. novicida (FTN_0055). Bruce Stocker's pioneer work on the genetics of Salmonella enterica serovar Typhimurium ( S. typhimurium ) has demonstrated the crucial importance of the aromatic biosynthetic pathway for bacterial virulence. Mutations...”
- “...pulmonary and systemic infection in mice (Kraemer et al., 2009 ). The gene tyrA ( FTN_0055 ), which encodes the enzyme prephenate dehydrogenase converting chorismate to tyrosine, was also hit in this in vivo screen, as was aroC . Notably, the tyrA gene is absent in...”
- Genome-wide screen in Francisella novicida for genes required for pulmonary and systemic infection in mice
Kraemer, Infection and immunity 2009 - “...were lost in all three organs. These were tyrA (FTN_0055) and folD (FTN_0417), both involved in amino acid metabolism; the intracellular growth locus protein D...”
- “...Berkeley FTN_0008 FTN_0012 FTN_0023 FTN_0028 FTN_0031 FTN_0045 FTN_0055 FTN_0111 FTN_0132 FTN_0133 FTN_0143 Gene name GENOME-WIDE SCREEN IN F. NOVICIDA VOL. 77,...”
- Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development
Pechous, Microbiology and molecular biology reviews : MMBR 2009 - “...FTN_0023 FTN_0028 FTN_0031 FTN_0035 FTN_0036 FTN_0045 FTN_0055 FTN_0090, FTN_1556, FTN_1061, FTN_0954 FTN_0096 FTN_0097 carA tmpT FTN_0028 FTN_0031 pyrF...”
FTL_0048 prephenate dehydrogenase. from Francisella tularensis subsp. holarctica
Aligns to 30:142 / 220 (51.4%), covers 63.0% of PF02153, 51.7 bits
- Francisella tularensis metabolism and its relation to virulence
Meibom, Frontiers in microbiology 2010 - “...the tyrA gene is absent in the Schu S4 strain but present in LVS ( FTL_0048 ). aroC encodes the enzyme performing the last step of chorismic acid synthesis. The gene aroE1 , which encodes shikimate-5-dehydrogenase, the fourth step of the biosynthetic pathway, was identified in...”
2pv7B / P43902 Crystal structure of chorismate mutase / prephenate dehydrogenase (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution (see paper)
Aligns to 25:149 / 280 (44.6%), covers 43.5% of PF02153, 50.7 bits
- Ligands: tyrosine; nicotinamide-adenine-dinucleotide (2pv7B)
VP0547 chorismate mutase/prephenate dehydrogenase from Vibrio parahaemolyticus RIMD 2210633
Aligns to 122:235 / 375 (30.4%), covers 63.6% of PF02153, 50.3 bits
P43902 prephenate dehydrogenase (EC 1.3.1.12) from Haemophilus influenzae (see paper)
HI1290 chorismate mutase / prephenate dehydrogenase (tyrA) from Haemophilus influenzae Rd KW20
Aligns to 117:239 / 377 (32.6%), covers 43.5% of PF02153, 49.9 bits
UTI89_C2933 bifunctional chorismate mutase/prephenate dehydratase from Escherichia coli UTI89
Aligns to 124:240 / 373 (31.4%), covers 63.6% of PF02153, 49.2 bits
Q02287 T-protein from Enterobacter agglomerans
Aligns to 124:239 / 373 (31.1%), covers 59.1% of PF02153, 48.5 bits
ECs3463 chorismate mutase-T / prephenate dehydrogenase from Escherichia coli O157:H7 str. Sakai
Aligns to 124:240 / 373 (31.4%), covers 63.6% of PF02153, 48.5 bits
A0A140N544 T-protein from Escherichia coli (strain B / BL21-DE3)
Aligns to 124:240 / 373 (31.4%), covers 63.6% of PF02153, 48.5 bits
TyrA / b2600 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
tyrA / P07023 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli (strain K12) (see 12 papers)
b2600 fused chorismate mutase T/prephenate dehydrogenase from Escherichia coli str. K-12 substr. MG1655
P07023 T-protein from Escherichia coli (strain K12)
Aligns to 124:240 / 373 (31.4%), covers 63.6% of PF02153, 47.2 bits
- Ferric Citrate Uptake Is a Virulence Factor in Uropathogenic Escherichia coli
Frick-Cheng, mBio 2022 - “...sufE Cysteine desulfuration protein 3.8 b1679 sufS Selenocysteine lyase 4.1 b1680 tyrA Chorismate mutase 3.7 b2600 ybdZ Enterobactin biosynthesis protein 6.1 b4511 ybgS Uncharacterized protein 4.3 b0753 ybiX PKHD-type hydroxylase 3.7 b0804 yciG Uncharacterized protein 4.5 b1259 yddM Putative DNA-binding transcriptional regulator 4.6 b1477 ydiE Uncharacterized...”
- Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions
Orth, BMC systems biology 2012 - “...(b0073) 2.00E-15 R00732 (R) III aroA (b0908) 5.00E-32 murA (b3189) 7.00E-8 R00733 (R) III tyrA (b2600) 2.80E-2 R01393 (R) I global orphan R01618 (R) IV glgP (b3428) 2.10 R01713 (F) I global orphan R01731 (F) IV tyrB (b4054) * R01785 (R) III rhaD (b3902) * R01902...”
- More than just a metabolic regulator--elucidation and validation of new targets of PdhR in Escherichia coli
Göhler, BMC systems biology 2011 - “...0.977 2.124 b0628 lipA * -0.075 3.914 b1596 ynfM 0.927 0.007 b4052 dnaB -0.018 3.864 b2600 tyrA 0.915 2.065 b0085 murE $ 0.167 3.659 b2505 yfgH 0.820 0.425 b0822 ybiV 0.284 3.653 b0333 prpC 0.729 0.021 b2683 ygaH -0.077 3.628 b0331 prpB 0.713 0.024 b0436 tig...”
- Genome-scale analysis to the impact of gene deletion on the metabolism of E. coli: constraint-based simulation approach
Xu, BMC bioinformatics 2009 - “...b1260 b0914 b1098 b1136 b1261, b1262 s0001 b2827 b1263, b1264 b3648 b1693, b2329 s0001 b2599, b2600 b3389 SS AAM FM ACM HM CM genes b0928 b1415 b1415 b2019, b2020 b2750, b2751 b3941 b3608 b2021, b2022 b2752, b2762 b2023, b2024 b2763, b2764 b2025, b2026 b3607 SS IITM...”
- Experimental and computational assessment of conditionally essential genes in Escherichia coli
Joyce, Journal of bacteriology 2006 - “...(b1261) trpC (b1262) trpD (b1263) trpE (b1264) tyrA (b2600) Group 8262 JOYCE ET AL. J. BACTERIOL. two experimentally defined essential genes. We then examined...”
- Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12
Sabina, Journal of bacteriology 2003 - “...hdeB b3524 b2601 b1261 b1264 b1493 b3517 b3320 b1263 b2600 b1260 b1973 b1262 b3340 b1779 b3321 b3308 b3304 b3616 b3339 b2155 b3829 b3317 b3296 b2913 b0631 b2416...”
- “...b1264 b1493 b3517 b3774 b1289 b2553 b0698 b1004 b0179 b2600 b1260 b3509 b1261 b2342 b2800 b3460 b3458 b1263 b1783 b0907 b0461 b2464 b0812 b0903 b1262 b0126...”
- Identification of enzymes and regulatory proteins in Escherichia coli that are oxidized under nitrogen, carbon, or phosphate starvation
Noda, Proceedings of the National Academy of Sciences of the United States of America 2007 - “...P0A9P1 P0A6M9 P0A6Q0 Q59346 P23847 P0A7A0 P23721 P0AD61 P07023 Protein name Protein MW Protein PI Dihydrolipoyl dehydrogenase, 3 Elongation factor G (EF-G), 2...”
- Analysis of the pmsCEAB gene cluster involved in biosynthesis of salicylic acid and the siderophore pseudomonine in the biocontrol strain Pseudomonas fluorescens WCS374
Mercado-Blanco, Journal of bacteriology 2001 - “...influenzae (P43902), Erwinia herbicola (Q02287), and E. coli (P07023). The homology was located in the N-terminal domain of TyrA. TyrA proteins are larger than...”
YP_0399 T-protein [includes: chorismate mutase and prephenate dehydrogenase] from Yersinia pestis biovar Medievalis str. 91001
Aligns to 124:239 / 373 (31.1%), covers 72.1% of PF02153, 46.8 bits
SO1362 chorismate mutase/prephenate dehydrogenase from Shewanella oneidensis MR-1
Aligns to 120:244 / 379 (33.0%), covers 61.7% of PF02153, 44.8 bits
- Design and analysis of mismatch probes for long oligonucleotide microarrays
Deng, BMC genomics 2008 - “...Mm Na+/H+ exchanger MMP0926 44921025 Mm Chemotaxis protein cheB MMP1559 45047480 Mm Formatedehydrogenase alpha subunit SO1362 24371479 So Chorismate mutase/prephenate dehydrogenase (tyrA) SO1779 24371479 So Decaheme cytochrome c (omcA) SO2452 24371479 So Alcohol dehydrogenase, zinc-containing *DvH: Desulfovibrio vulgaris str. Hildenborough ; Mm: Methanococcus maripaludis ; So:...”
Dde_3485 Prephenate dehydrogenase from Desulfovibrio desulfuricans G20
Dde_3485 prephenate dehydrogenase/arogenate dehydrogenase family protein from Oleidesulfovibrio alaskensis G20
Aligns to 4:121 / 260 (45.4%), covers 44.2% of PF02153, 44.7 bits
ETAE_2836 bifunctional chorismate mutase/prephenate dehydrogenase from Edwardsiella tarda EIB202
Aligns to 131:239 / 373 (29.2%), covers 69.5% of PF02153, 42.9 bits
BT3933 prephenate dehydrogenase (EC 1.3.1.13) from Bacteroides thetaiotaomicron VPI-5482
Aligns to 24:151 / 257 (49.8%), covers 68.8% of PF02153, 41.9 bits
- mutant phenotype: Important for fitness in defined media. Distantly related (under 25% identity) to the prephenate dehydrogenase portion of E. coli tyrA. This is sometimes annotated as chorismate mutase as well, but it lacks that domain.
O30012 prephenate dehydrogenase (EC 1.3.1.12); prephenate dehydratase (EC 4.2.1.51); chorismate mutase (EC 5.4.99.5) from Archaeoglobus fulgidus (see paper)
AF0227 chorismate mutase/prephenate dehydratase (pheA) from Archaeoglobus fulgidus DSM 4304
Aligns to 29:138 / 620 (17.7%), covers 48.7% of PF02153, 39.5 bits
- Prephenate dehydratase from the aphid endosymbiont (Buchnera) displays changes in the regulatory domain that suggest its desensitization to inhibition by phenylalanine
Jiménez, Journal of bacteriology 2000 - “...pombe, O14361), PDTARCFU (Archaeoglobus fulgidus, O30012), PDTAQUAE (Aquifex aeolicus, O67085), PDTXANCA (Xanthomonas campestris, O87954), PDTPSEAER (P....”
- Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus
Lim, Extremophiles : life under extreme conditions 2009 (PubMed)- “...proteins or fusions combining two activities. Gene locus AF0227 of Archaeoglobus fulgidus is predicted to encode a fusion protein, AroQ, containing all three...”
- “...to be particularly interesting since its gene at locus AF0227 is predicted to encode a protein containing three domains harboring putative CM, PDT, and PDHG...”
- Evolution of gene fusions: horizontal transfer versus independent events
Yanai, Genome biology 2002 - “...of the fused gene (Figure 4a,4b ). The single archaeal fusion, the Arachaeoglobus fulgidus protein AF0227, belongs to one of these clusters and shows a strongly supported affinity with the ortholog from the hyperthermophilic bacterium Thermotoga maritima . (Figure 4a,4b ). Given the broad distribution of...”
- “...(COG1605); (b) prephenate dehydratase (COG0077). Protein designations are as in Figure 2 . The protein AF0227 contains a prephenate dehydrogenase domain in addition to the chorismate mutase and prephenate dehydratase domains. Figure 5 Phylogenetic trees for fusion-linked COGs: and subunits of acetyl-CoA carboxylase. (a) subunit (domain)...”
- Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus
Tang, Proceedings of the National Academy of Sciences of the United States of America 2002 - “...() AF1049 () AF1987 () AF1017 () AF0790 () AF2390 () AF0227 () AF0896 () AF0701 () AF1489 () AF1277 () AF1444 () AF0208 () AF0595 () AF0592 () AF0597 () AF2236...”
TyrAAT2 / Q9LMR3 arogenate dehydrogenase (EC 1.3.1.78) from Arabidopsis thaliana (see paper)
TYRA2_ARATH / Q9LMR3 Arogenate dehydrogenase 2, chloroplastic; TyrAAT2; EC 1.3.1.78 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LMR3 arogenate dehydrogenase (NADP+) (EC 1.3.1.78) from Arabidopsis thaliana (see 2 papers)
AT1G15710 prephenate dehydrogenase family protein from Arabidopsis thaliana
NP_173023 prephenate dehydrogenase family protein from Arabidopsis thaliana
Aligns to 73:223 / 358 (42.2%), covers 95.5% of PF02153, 38.3 bits
- function: Involved in the biosynthesis of tyrosine. Has a weak prephenate dehydrogenase activity.
catalytic activity: L-arogenate + NADP(+) = CO2 + L-tyrosine + NADPH (RHEA:15417) - The cytosolic aminotransferase VAS1 coordinates aromatic amino acid biosynthesis and metabolism
Wu, Science advances 2024 - “...and growth conditions The Arabidopsis ( A. thaliana ) T-DNA insertion mutants adh2 (SALK_001765, in At1g15710) and vas1-1 (SALK_207250, in At1g80360) are in the Col-0 background. The adh2 mutant was provided by Y. Qi (Tsinghua University, China). The vas1 mutant was purchased from AraShare ( http://arashare.cn...”
- Two independently evolved natural mutations additively deregulate TyrA enzymes and boost tyrosine production in planta
Lopez-Nieves, The Plant journal : for cell and molecular biology 2022 (PubMed) (secret) - TRUEE; a bioinformatic pipeline to define the functional microRNA targetome of Arabidopsis
Wong, The Plant journal : for cell and molecular biology 2022 - “...miR5021 Yes AT3G23890 3.559 TOPII Topoisomerase II miR414 Yes AT5G40340 2.765 Tudor/PWWP/MBT superfamily protein miR8177 AT1G15710 2.618 Prephenate dehydrogenase family protein miR5652 AT1G62670 2.529 RPF2 rna processing factor 2 a miR414 Yes AT3G11810 2.118 (1 of 2) PTHR33133:SF7 F26K24.10 miR414 Yes AT5G55300 2.118 TOP1ALPHA DNA topoisomerase...”
- Imbalance of tyrosine by modulating TyrA arogenate dehydrogenases impacts growth and development of Arabidopsis thaliana
de, The Plant journal : for cell and molecular biology 2019 (PubMed) (secret) - Transcriptional analyses of natural leaf senescence in maize
Zhang, PloS one 2014 - “...protein chloroplast GRMZM2G454719 1.52 0.96 AT1G22410 \ class-II DAHP synthetase-like protein chloroplast GRMZM2G365961 2.51 2.33 AT1G15710 \ prephenate dehydrogenase family protein chloroplast GRMZM2G164562 1.44 1.99 AT1G48850 EMB1144 chorismate synthase chloroplast, stroma GRMZM2G115841 2.17 1.41 AT2G27820 PD1 arogenate dehydratase 3 chloroplast GRMZM2G003109 2.09 0.39 AT5G05730 ASA1 anthranilate...”
- Genetic dissection of vitamin E biosynthesis in tomato
Almeida, Journal of experimental botany 2011 - “...At2g22250 (475) Chloroplast U567172 Chloroplast SL2.31sc06101 C2_At4g39830 4 (61 cM) Arogenate dehydrogenase (TyrA, EC 1.3.1.78) At1g15710 ( 358) Chloroplast U567861 (1) Chloroplast SL2.31sc03731 C2_At5g34850 7 (0.4 cM) At5g34930 (640) Chloroplast ( Rippert et al., 2009 ) U570951 (2) Chloroplast SL2.31sc03771 T1212 9 (48 cM) Tyrosine aminotransferase...”
- Transcriptome analysis of the Arabidopsis megaspore mother cell uncovers the importance of RNA helicases for plant germline development
Schmidt, PLoS biology 2011 - “...factors. Arabidopsis PUMILIO23 (AtPUM23 ) is an RNA-binding protein located in the nucleus [40] . AT1G15710 is a prehenate dehydrogenase potentially involved in tyrosin biosynthesis. Also YUCCA2 , a gene involved in auxin biosynthesis and AT1G29440 , encoding an auxin-responsive gene related to SMALL AUXIN UPREGULATED68...”
- The Biosynthetic Pathways for Shikimate and Aromatic Amino Acids in Arabidopsis thaliana
Tzin, The arabidopsis book 2010 - “...TyrA enzymes were identified: TyrA1 (At5g34930) and TyrA2 (At1g15710) (Rippert and Matringe, 2002b, a; Rippert et al., 2009). A second possible route of Tyr...”
- “...PAT TyrA1, ADS1 TyrA2, ADS2 At5g34930 At1g15710 2.6.1.79 1.3.1.43 1.3.1.43 Prephenate Aminotransferase Arogenate Dehydrogenase Arogenate Dehydrogenase PDH AAAAT...”
- More
- Imbalance of tyrosine by modulating TyrA arogenate dehydrogenases impacts growth and development of Arabidopsis thaliana.
de, The Plant journal : for cell and molecular biology 2019 (PubMed)- GeneRIF: These results revealed that TyrA1 and TyrA2 have distinct and overlapping functions in flower and leaf development, respectively, and that imbalance of tyrosine, caused by altered TyrA activity and regulation, impacts growth and development of Arabidopsis. [TyrA2]
LOC100284089 arogenate dehydrogenase from Zea mays
Aligns to 105:218 / 403 (28.3%), covers 70.8% of PF02153, 37.9 bits
AroDH-1 / B4FY98 arogenate dehydrogenase 1 (EC 1.3.1.43) from Zea mays (see paper)
Aligns to 96:230 / 360 (37.5%), covers 69.5% of PF02153, 37.9 bits
B6SS03 arogenate dehydrogenase [NAD(P)+] (EC 1.3.1.79) from Zea mays (see paper)
GRMZM2G365961, LOC100281078 arogenate dehydrogenase from Zea mays
Aligns to 83:197 / 349 (33.0%), covers 68.8% of PF02153, 37.3 bits
- Chloroplast-associated metabolic functions influence the susceptibility of maize to Ustilago maydis
Kretschmer, Molecular plant pathology 2017 (secret) - Numerous genetic loci identified for drought tolerance in the maize nested association mapping populations
Li, BMC genomics 2016 - “...0.66 + PH GRMZM2G430680 Inside gene Glucan synthase-like 12 0.34 6 85797877 0.25 + PH GRMZM2G365961 52 Prephenate dehydrogenase family protein 0.15 6 88935877 0.40 + PH GRMZM2G150302 13001 Nucleotide-diphospho-sugar transferases superfamily protein/glycosyltransferase family 43 protein 0.41 6 119695193 0.50 - HKW GRMZM2G368678 Inside gene Binding/expressed...”
- Transcriptional analyses of natural leaf senescence in maize
Zhang, PloS one 2014 - “...class-II DAHP synthetase-like protein chloroplast GRMZM2G454719 1.52 0.96 AT1G22410 \ class-II DAHP synthetase-like protein chloroplast GRMZM2G365961 2.51 2.33 AT1G15710 \ prephenate dehydrogenase family protein chloroplast GRMZM2G164562 1.44 1.99 AT1G48850 EMB1144 chorismate synthase chloroplast, stroma GRMZM2G115841 2.17 1.41 AT2G27820 PD1 arogenate dehydratase 3 chloroplast GRMZM2G003109 2.09 0.39...”
- Identification and characterization of the maize arogenate dehydrogenase gene family
Holding, Journal of experimental botany 2010 - “...acid similarities in the maize AroDH family AroDH-1 AroDH-2 AroDH-3 AroDH-4 Accession no. BT085368.1 LOC100284089 LOC100281078 BT068692.1 Transcript (bp) 1477 1417 1336 1327 Protein (amino acids) 360 406 349 392 ID to AroDH-1 mRNA (coverage and max ID) 73% and 85% 83% and 93% 65% and...”
- Comparative proteomic analysis of maize (Zea mays L.) seedlings under rice black-streaked dwarf virus infection
Yue, BMC plant biology 2018 - “...acids pathway, one significantly induced protein (C0P3B4) and five significantly reduced proteins (K7VBU7, K7VC35, B8A068, B6SS03 and K7U2E4) were identified and in the purine metabolism pathway, one significantly induced protein (K7TPZ5) and one significantly reduced protein (K7UGQ5) were identified (Table 1 ). Table 1 Identification of...”
- “...0.025750889 K7VC35 Zm.66568 S-adenosylmethionine synthethase 42.54 0.770235935 0.025440529 B8A068 Zm.20018 S-adenosylmethionine synthethase 43.072 0.757097792 0.012769647 B6SS03 Zm.155641 Arogenate dehydrogenase isoform 2 38.561 0.77589852 0.023596168 K7U2E4 Zm.24636 Amine oxidase 82.989 0.779698303 0.04484565 Purine metabolism K7TPZ5 Zm.138895 Aminoimidazolecarboximide ribonucleotide transformylase 65.704 1.222222222 0.0327844 K7UGQ5 LOC100275070 Putative adenine phosphoribosyltransferase...”
G7J2F0 Prephenate dehydrogenase from Medicago truncatula
Aligns to 22:146 / 239 (52.3%), covers 55.2% of PF02153, 35.5 bits
G7J2E9 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Medicago truncatula (see paper)
Aligns to 22:146 / 268 (46.6%), covers 55.2% of PF02153, 35.2 bits
5t9fB / I1MYY4 Prephenate dehydrogenase n222d mutant from soybean (see paper)
Aligns to 17:137 / 253 (47.8%), covers 68.8% of PF02153, 35.2 bits
- Ligands: nadp nicotinamide-adenine-dinucleotide phosphate; tyrosine (5t9fB)
Q5Z9H5 Os06g0708832 protein from Oryza sativa subsp. japonica
Aligns to 91:239 / 353 (42.2%), covers 70.1% of PF02153, 35.0 bits
- Physiological and Proteomic Analysis of Various Priming on Rice Seed under Chilling Stress
Zhang, Plants (Basel, Switzerland) 2024 - “...Os07g0681400 Q7XHW4 Probable calcium-binding protein 3.629 3.103 UP Os02g0169900 Q6H6B9 Inositol-1-monophosphatase 0.010 0.010 Down Os06g0708832 Q5Z9H5 Similar to arogenate dehydrogenase. 0.010 0.010 Down Os02g0738900 Q0DXR0 Dynamin GTPase 0.135 0.179 Down Os05g0595100 Q8LNZ3 UDP-glucose 4-epimerase 0.190 0.186 Down Os01g0633100 Q7G065 Glucose-1-phosphate adenylyltransferase large subunit 0.232 6.741 Down...”
PAPC_STRPR / P72540 4-amino-4-deoxyprephenate dehydrogenase; EC 1.3.1.121 from Streptomyces pristinaespiralis (see paper)
Aligns to 23:165 / 296 (48.3%), covers 62.3% of PF02153, 34.0 bits
- function: Involved in pristinamycin I biosynthesis (PubMed:9044253). Probably catalyzes the formation of 3-(4-aminophenyl)pyruvate from 4- amino-4-deoxyprephenate (Probable).
catalytic activity: 4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH (RHEA:59380)
CC1574 conserved hypothetical protein from Caulobacter crescentus CB15
Aligns to 15:135 / 286 (42.3%), covers 73.4% of PF02153, 32.2 bits
PPTG_08889 pyrroline-5-carboxylate reductase from Phytophthora nicotianae INRA-310
Aligns to 102:212 / 356 (31.2%), covers 59.7% of PF02153, 32.1 bits
HVO_1312 Prephenate dehydrogenase from Haloferax volcanii DS2
Aligns to 16:147 / 272 (48.5%), covers 64.3% of PF02153, 32.0 bits
- Generation of comprehensive transposon insertion mutant library for the model archaeon, Haloferax volcanii, and its use for gene discovery
Kiljunen, BMC biology 2014 - “...synthase [NADPH] large chain H295/24-65 Proline 1,051,586; - HVO_1153 Hypothetical protein H295/12-1 Tyrosine 1,198,243; + HVO_1312 Prephenate dehydrogenase H295/16-1 Isoleucine 578,651; - HVO_0644, leuA1 2-isopropylmalate synthase/(R)-citramalate synthase H295/24-63 Phenylalanine 399,114; - HVO_0449, pheA1 Prephenate dehydratase H295/9-8 Valine, Leucine, Isoleucine 1,374,516; - HVO_1506, ilvC Ketol-acid reductoisomerase H295/4-26...”
- “...subunit) and the other in HVO_1153 (hypothetical protein). In the tyrosine auxotroph the transposon interrupted HVO_1312 (prephenate dehydrogenase, a known enzyme on the tyrosine biosynthesis pathway). The isoleucine auxotroph harbored the transposon in leuA1 , proposed to encode either 2-isopropylmalate synthase or highly similar (R)-citramalate synthase....”
K4C5K7 Arogenate dehydrogenase from Solanum lycopersicum
Aligns to 26:148 / 272 (45.2%), covers 73.4% of PF02153, 31.3 bits
- Proteome-wide identification of non-histone lysine methylation in tomato during fruit ripening
Xiao, Journal of advanced research 2022 - “...A0A3Q7HE49 91, K Peptide-methionine (R)-S-oxide reductase Methyl chloroplast A0A3Q7HK83 206, K Glutathione peroxidase Trimethyl chloroplast K4C5K7 262, K Arogenate dehydrogenase Methyl chloroplast P00060 80, K Cytochrome c Dimethyl,Trimethyl mitochondria 94, K Trimethyl A0A3Q7F9X5 81, K; 82, K;95, K;96, K;100, R PREDICTED: cytochrome c Methyl mitochondria P27065...”
- “...bystin-like protein Methyl cytoplasm K4B3H5 161, R NADH dehydrogenase [ubiquinone] iron-sulfur protein 8 Methyl chloroplast K4C5K7 260, R Arogenate dehydrogenase Methyl chloroplast A9LRT7 188, K Isopentenyl diphosphate isomerase Methyl chloroplast Methylated proteins related to carbohydrate biosynthetic P27065 14, K Ribulose bisphosphate carboxylase large chain Dimethyl, Trimethyl...”
PF1703 prephenate dehydrogenase from Pyrococcus furiosus DSM 3638
Aligns to 18:148 / 148 (88.5%), covers 61.0% of PF02153, 28.5 bits
papC / BAD21141.1 4-amino-4-deoxyprephenate dehydrogenase from Streptomyces venezuelae (see paper)
Aligns to 20:136 / 322 (36.3%), covers 46.8% of PF02153, 27.1 bits
Or search for genetic data about PF02153 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory