Family Search for PF02622 (DUF179)
PF02622 hits 34 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
VC0467 hypothetical protein from Vibrio cholerae O1 biovar eltor str. N16961
Aligns to 12:174 / 187 (87.2%), covers 100.0% of PF02622, 183.6 bits
- Regulatory (pan-)genome of an obligate intracellular pathogen in the PVC superphylum
de, The ISME journal 2016 - “...Kelley and Sternberg, 2009 ) we noted a structural similarity to the predicted transcriptional regulator VC0467 from Vibrio cholerae . Akin to Euo, HrcA is not present in the Lentisphaerae, Verrucomicrobia and Planctomycetes (which seems to encode RpoH/ 32 ) ( Wecker et al. , 2009...”
- Global gene expression and phenotypic analysis of a Vibrio cholerae rpoH deletion mutant
Slamti, Journal of bacteriology 2007 - “...Cytochrome c-type protein YecK Thioredoxin 2 vc0466 vc0467 vc0469 vc0490 vc0977 vc1055 vc1358 vc1871 vc2735 vc0177* vc0189 vc0886 vc1080 vc2486 vc2663...”
- “...found to be RpoH regulated in E. coli (e.g., vc0466, vc0467, vc0468, and vc0469). Twelve genes in the V. cholerae RpoH regulon do not have E. coli homologs; the...”
CV_3909 conserved hypothetical protein from Chromobacterium violaceum ATCC 12472
Aligns to 21:179 / 192 (82.8%), covers 100.0% of PF02622, 180.2 bits
YqgE / b2948 DUF179 domain-containing protein YqgE from Escherichia coli K-12 substr. MG1655 (see 3 papers)
b2948 orf, hypothetical protein from Escherichia coli str. K-12 substr. MG1655
P0A8W5 UPF0301 protein YqgE from Escherichia coli (strain K12)
Aligns to 12:174 / 187 (87.2%), covers 100.0% of PF02622, 178.3 bits
- Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA
Barbosa, Journal of bacteriology 2000 - “...changeb Increased expression acnA acrA aldA b0447 b0853 b1448 b2889 b2948 cobU fumC galK galT gatA gatC gltA gshB hemB inaA map marA marB marR mdaA mdaB mglB...”
- “...mdaB, yhbW Encoding unknown proteins ...............b1448, b2530, b2889, b2948, ybjC, yfaE, yggJ 3471 3472 BARBOSA AND LEVY FIG. 3. Northern blot analysis of...”
- The Escherichia coli proteome: past, present, and future prospects
Han, Microbiology and molecular biology reviews : MMBR 2006 - “...(DIGE 4.5-6.5) YnjE P78067 YodA P76344 YqgE YqhD YqhE P0A8W5 Q46856 YqiC YqiK YqjD YraM YraP YraR YrbC YrbF Q46868 P77306 P64581 P45464 P64596 P45469 P0ADV7...”
SEEHRA37_19825 YqgE/AlgH family protein from Salmonella enterica subsp. enterica serovar Heidelberg str. SARA37
Aligns to 12:174 / 187 (87.2%), covers 100.0% of PF02622, 175.9 bits
SPO0296 YqgE/AlgH family protein from Ruegeria pomeroyi DSS-3
Aligns to 12:171 / 184 (87.0%), covers 100.0% of PF02622, 175.4 bits
STM3096 putative transcriptional regulator from Salmonella typhimurium LT2
Aligns to 12:174 / 187 (87.2%), covers 100.0% of PF02622, 175.2 bits
Bamb_0737 protein of unknown function DUF179 from Burkholderia cepacia AMMD
Aligns to 19:179 / 192 (83.9%), covers 100.0% of PF02622, 175.1 bits
- Proteogenomic Analysis of Burkholderia Species Strains 25 and 46 Isolated from Uraniferous Soils Reveals Multiple Mechanisms to Cope with Uranium Stress
Agarwal, Cells 2018 - “...expression of uncharacterized proteins in SRS-46 like UPF0234 protein Bmul_0741/BMUL1_02519, UPF0307 protein Bcep18194_A4194, UPF0301 protein Bamb_0737 was found higher in the presence of U. These hetherto uncharacterized proteins may be involved in conferring U resistance or providing some form of protection to the bacterial cells under...”
- “...proteins in SRS-46, such as the UPF0234 protein Bmul_0741/BMUL1_02519, UPF0307 protein Bcep18194_A4194, and UPF0301 protein Bamb_0737, which were higher in the presence of uranium. Other studies on Geobacter sp., Microbacterium sp., Acidithiobacillus sp., have also led to the identification of uncaracterized proteins under uranium stress [...”
BCAL3142 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 19:179 / 192 (83.9%), covers 100.0% of PF02622, 175.1 bits
- High confidence prediction of essential genes in Burkholderia cenocepacia
Juhas, PloS one 2012 - “...and valS , as well as the so far uncharacterized genes BCAL1882 , BCAL2769 , BCAL3142 and BCAL3369 has been confirmed experimentally in B. cenocepacia . Conclusions/Significance We report on the identification of essential genes using a novel bioinformatics strategy and provide bioinformatics and experimental evidence...”
- “...were previously demonstrated to be essential in another organism, namely: infB, gyrB, ubiB, valS , BCAL3142 and BCAL3369 ( Figure S2 ). Gene essentiality is condition dependent. For example, while the referred DEG database lists 1617 E. coli MG1655 genes as essential, other experimentally more rigorous...”
ATU_RS03855 YqgE/AlgH family protein from Agrobacterium fabrum str. C58
Atu0781 hypothetical protein from Agrobacterium tumefaciens str. C58 (Cereon)
Aligns to 24:188 / 201 (82.1%), covers 100.0% of PF02622, 171.8 bits
- Dual adhesive unipolar polysaccharides synthesized by overlapping biosynthetic pathways in Agrobacterium tumefaciens
Onyeziri, Molecular microbiology 2022 - “...2015 ). Twenty-three translated gene sequences (d naK, prfC, hemN, hamI, truA, glyS, coxC , ATU_RS03855, ATU_RS07710, hom, rplB, rpoC, rpoB, murC, hemF , ATU_RS12850, acnA, leuS, cgtA, secA, plsC, aroB, lysC ) from the strain A. fabrum C58 (NCBI accession: GCA_000092025.1) were used as reference...”
- Diversification of plasmids in a genus of pathogenic and nitrogen-fixing bacteria
Weisberg, Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2022 (secret)
PA0405 hypothetical protein from Pseudomonas aeruginosa PAO1
Q9RQ16 UPF0301 protein AlgH from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Aligns to 18:176 / 189 (84.1%), covers 100.0% of PF02622, 170.3 bits
- Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa
Tortuel, Microbiology spectrum 2022 - “...factor RpoS 16.13 8.26 PPGPP metabolism PA5338 spoT Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase 2.05 1.01 Envelope stress response PA0405 algH AlgH 2.27 PA0762 algU Sigma factor AlgU AlgU 13.46 33.43 PA0763 mucA Anti-sigma factor MucA AlgU 9.89 PA0764 mucB Negative regulator for alginate biosynthesis MucB AlgU 11.42 PA0765 mucC...”
- General and condition-specific essential functions of Pseudomonas aeruginosa
Lee, Proceedings of the National Academy of Sciences of the United States of America 2015 - “...to be essential. The upstream gene on the left (PA0405) has a high density of insertions and is considered nonessential. Note that the orientation of the...”
- “...expression of PA0404. The forward-oriented insertions in PA0405 apparently circumvent polarity on PA0404 expression through the activity of the promoter. Fig....”
- Solution structure and properties of AlgH from Pseudomonas aeruginosa
Urbauer, Proteins 2015 - “...development. MATERIALS AND METHODS AlgH Production Recombinant Pseudomonas aeruginosa (strain PA01) AlgH protein (UniProt entry Q9RQ16) was expressed in Escherichia coli and purified as described previously 32 , 33 . Production of AlgH uniformly isotopically labeled with 15 N or with both 15 N and 13...”
K7G93_001967 YqgE/AlgH family protein from Pasteurella canis
Aligns to 12:172 / 185 (87.0%), covers 100.0% of PF02622, 169.5 bits
- Virulence-associated Genome Sequences of Pasteurella canis and Unique Toxin Gene Prevalence of P. canis and Pasteurella multocida Isolated from Humans and Companion Animals
Yoshida, Annals of laboratory medicine 2023 - “...WGS ( cdtAcdtBcdtC and K7G93_001965) but not in the P. multocida WGS. The loci K7G93_001965, K7G93_001967, and DR93_66 are predicted to encode hypothetical proteins. Accuracy of primer sequences for PCR Primer sequences are located within the corresponding open reading frames to amplify sequences with expected sizes...”
- “...multocida ATCC 43137(T) (GenBank accession no. CP008918.1) (lower). Asterisks show putative Holliday junction resolvase. K7G93_001965, K7G93_001967, and DR93_66 represent loci encoding hypothetical proteins. Abbreviations: relA , GTP diphosphokinase; rlmD and rumA , 23S rRNA (uracil(1939)-C(5))-methyltransferase; recO , DNA repair protein; rsmE , 16S rRNA (uracil(1498)-N(3))-methyltransferase; eno...”
SMc00019 CONSERVED HYPOTHETICAL PROTEIN from Sinorhizobium meliloti 1021
Aligns to 24:188 / 201 (82.1%), covers 100.0% of PF02622, 168.7 bits
- A novel symbiovar (aegeanense) of the genus Ensifer nodulates Vigna unguiculata
Tampakaki, Journal of the science of food and agriculture 2017 (PubMed)- “...genes (recA, glnII, gyrB, truA, thrA and SMc00019), rhizobial isolates were classified within the species Ensifer fredii. However, symbiotic gene phylogenies,...”
- “...(glutamine synthetase II), gyrB (DNA gyrase B), SMc00019 (conserved hypothetical protein), truA (RNA pseudouridine synthase A), and thrA (homoserine...”
- Replicon-dependent differentiation of symbiosis-related genes in Sinorhizobium strains nodulating Glycine max
Guo, Applied and environmental microbiology 2014 - “...and related microevolutionary mechanisms, three housekeeping genes (SMc00019, truA, and thrA) and 16 symbiosis-related genes on the chromosome (7 genes), pSymA...”
- “...analyses were carried out for three housekeeping genes (SMc00019, truA, and thrA), six well-known symbiosis genes involved in regulation and biosynthesis of Nod...”
- Genetic divergence of bradyrhizobium strains nodulating soybeans as revealed by multilocus sequence analysis of genes inside and outside the symbiosis island
Zhang, Applied and environmental microbiology 2014 - “...sequence analysis of three phylogenetic and taxonomic markers (SMc00019, thrA, and truA). This was also supported by analyses of eight genes outside the...”
- “...tree for rhizobia (7, 17). Then, three core genes, SMc00019, truA, and thrA, both alone and in combination, were found to be able to produce phylogenies...”
- Robust markers reflecting phylogeny and taxonomy of rhizobia
Zhang, PloS one 2012 - “...was compared to the genomic ANI. This allowed us to identify three housekeeping genes ( SMc00019 - truA - thrA ) whose ANI reflected the intraspecies and interspecies genomic ANI among rhizobial strains, revealing an ANI gap (2%) between the inter- and intra-species comparisons. The intraspecies...”
- “..., Mesorhizobium , Sinorhizobium and Rhizobium . Some widely studied strains should be renamed. The SMc00019 - truA - thrA ANI also correlates well with the genomic ANI of strains in Agrobacterium , Methylobacterium , Ralstonia , Rhodopseudomonas , Cupriavidus and Burkholderia , suggesting their wide...”
lpl0620 hypothetical protein from Legionella pneumophila str. Lens
Aligns to 16:174 / 187 (85.0%), covers 98.1% of PF02622, 167.5 bits
lpp0636 hypothetical protein from Legionella pneumophila str. Paris
lpg0586 transcriptional regulator from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Aligns to 16:174 / 187 (85.0%), covers 98.1% of PF02622, 167.5 bits
- The Legionella pneumophila LetA/LetS two-component system exhibits rheostat-like behavior
Edwards, Infection and immunity 2010 - “...2 3 stuC arcB lpp0351 lpp1170 lpp2523 lpp2788 lpp0636 lpp1115 lpp1116 lpp1535 lpp1760 lpp2071 lpp2083 lpp2084 lpp2133 lpl0329 lpl1176 lpl2376 lpl2657 lpl0620...”
- “...sigma factor gene rpoE, putative transcription factor lpp0636, type IV fimbrial pilin-related genes lpg0632 and lpp0686, and the virulence-associated enhA3...”
- Transcriptomic changes of Legionella pneumophila in water
Li, BMC genomics 2015 - “...polymerase sigma-54 factor lpg0477 1.44 Transcription repair coupling factor lpg0954 mfd 2.04 2.14 Transcriptional regulator lpg0586 1.24 3.75 4.48 Transcriptional regulator, ArsR family lpg2723 3.63 1.18 Transcriptional regulator, AsnC family lpg1486 2.33 Transcriptional regulator, DeoR family lpg2167 1.76 Transcriptional regulator, LuxR family lpg2524 1.52 1.73 Transcriptional...”
- “...eight different orthologous groups. According to the microarray data, six of the selected genes ( lpg0586 , lpg0846 , lpg1206 , lpg1659 , lpg2316 ( bdhA ) and lpg2524 ) were significantly up-regulated in water at two or all three time points, while the remaining four...”
- The Legionella pneumophila LetA/LetS two-component system exhibits rheostat-like behavior
Edwards, Infection and immunity 2010 - “...of California, Berkeley lpg0277 lpg1168 lpg2457 lpg2732 lpg0586 lpg1114ac lpg1115 lpg1577 lpg1796 lpg2132 lpg2145 lpg2146 lpg2181 lpg2524 Gene name VOL. 78,...”
- SigmaS controls multiple pathways associated with intracellular multiplication of Legionella pneumophila
Hovel-Miner, Journal of bacteriology 2009 - “...2017 by University of California, Berkeley lpg0490 lpg0586 lpg0853 lpg1260 lpg1292 lpg1438 lpg1446 lpg1577 lpg1782 lpg1796 lpg2138 lpg2376 lpg2723 Protein...”
PD1276 transcriptional regulator from Xylella fastidiosa Temecula1
Aligns to 17:175 / 188 (84.6%), covers 100.0% of PF02622, 167.4 bits
- Exploring the xylem-sap to unravel biological features of Xylella fastidiosa subspecies pauca ST53 in immune, resistant and susceptible crop species through metabolomics and in vitro studies
Surano, Frontiers in plant science 2023 - “...Virulence: protein suggested to regulate pathogenicity and disease symptoms ( Hernandez-Martinez etal., 2006 ) algH PD1276 B9J09_03780 Virulence: exopolysaccharide production, biofilm formation, and maintainance ( Shi etal., 2013 ) cvaC PD0215 B9J09_01180 Virulence: toxin Colicin V encodes a bacteriocin precursor proposed to be a defense mechanism...”
- Identification of a response regulator involved in surface attachment, cell-cell aggregation, exopolysaccharide production and virulence in the plant pathogen Xylella fastidiosa
Voegel, Molecular plant pathology 2013 (secret) - Characterization of regulatory pathways in Xylella fastidiosa: genes and phenotypes controlled by algU
Shi, Applied and environmental microbiology 2007 - “...protein 0.617 Lower Regulatory functions/activators/repressors algH PD1276 Transcriptional regulator 0.652 Lower PD1926 Fimbrial protein, pilus assembly protein...”
B9J09_03780 YqgE/AlgH family protein from Xylella fastidiosa subsp. pauca
Aligns to 17:175 / 188 (84.6%), covers 100.0% of PF02622, 166.5 bits
RSP_0999 hypothetical protein from Rhodobacter sphaeroides 2.4.1
Aligns to 12:171 / 184 (87.0%), covers 100.0% of PF02622, 162.8 bits
- The essential Rhodobacter sphaeroides CenKR two-component system regulates cell division and envelope biosynthesis
Lakey, PLoS genetics 2022 - “...5.9E-06 -1.64 1.9E-03 -2.07 8.8E-05 + N 2758300 * 2.8 * 1.5 * -- -- RSP_0999 RSP_0999 putative transcriptional regulator N N TCG CGCGACTG TGG C 1.37 4.5E-05 n.s. n.s. n.s. n.s. + N 1273100 1.6 -- -- -- RSP_2633 ccmF Cytochrome c maturation protein CcmF...”
- Convergence of the transcriptional responses to heat shock and singlet oxygen stresses
Dufour, PLoS genetics 2012 - “...extra-chromosomal element functions Transposon functions RSP_3007 Unknown function Unknown function RSP_0126, RSP_0362, RSP_0363, RSP_0408, RSP_0719, RSP_0999, RSP_1104, RSP_1193, RSP_1204, RSP_1238, RSP_1241, RSP_1360, RSP_1406, RSP_1549, RSP_1563, RSP_1573, RSP_1581, RSP_1615, RSP_1671, RSP_1684, RSP_1743, RSP_1852, RSP_2121, RSP_2125, RSP_2214, RSP_2219, RSP_2387, RSP_2638, RSP_2640, RSP_2641, RSP_2739, RSP_2763, RSP_2764, RSP_2816, RSP_2952, RSP_2953,...”
HI0304 conserved hypothetical protein from Haemophilus influenzae Rd KW20
Aligns to 13:172 / 186 (86.0%), covers 99.4% of PF02622, 162.7 bits
- Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae
Gladitz, Nucleic acids research 2005 - “...Rd and HI0186 is also a transcriptional regulator which selected Haemophilus phage. A third gene, HI0304, shows protein homology to transcriptional regulators and has a high value. Restriction/modification genes The genes HI1055 and HI1058 have strong nucleotide homology (95%) to restriction/modification (R/M) genes from Neisserial strains....”
- “...acyltransferase) HI0282 36 248 35.42 LP 7.1 72.05 Conserved hypothetical protein (homol. to transcriptional regulator) HI0304 39 186 41.25 PM 2.5 68.96 Conserved hypothetical protein (homol. to lysine 2,3-aminomutase) HI0329 38 338 32.18 HFRD 0 66.55 Conserved hypothetical protein HI0510 42 239 36.98 HP1 0 59.91...”
CCNA_03506 transcriptional regulator, algH from Caulobacter crescentus NA1000
Aligns to 22:182 / 195 (82.6%), covers 100.0% of PF02622, 161.7 bits
- Gene network analysis identifies a central post-transcriptional regulator of cellular stress survival
Tien, eLife 2018 - “...4.46, 5.44 Rockhopper, Sliding window 35767403577696 (-),35775503577600 (-, I, S) alpha/beta hydrolase family protein GGUUUGUGAAGGG CCNA_03506 - 3.27, 4.10 Rockhopper, Sliding window 36640903664677 (+),36641003664175 (+, I, S) putative transcriptional regulator GUUGGGGGG CCNA_03589 sigT 3.58 Rockhopper 37439533744558 (-) RNA polymerase EcfG family sigma factor sigT - CCNA_03590...”
NGO0569 hypothetical protein from Neisseria gonorrhoeae FA 1090
Aligns to 12:169 / 182 (86.8%), covers 100.0% of PF02622, 160.0 bits
- Deep sequencing-based analysis of the anaerobic stimulon in Neisseria gonorrhoeae
Isabella, BMC genomics 2011 - “...protein NGO0119 5.4 5.1 Neisseria-specific protein, uncharacterized; possible ribonuclease NGO0165 3.2 5.9 Neisseria-specific protein, uncharacterized NGO0569 3.8 2.1 Conserved hypothetical protein (possible transcriptional regulator) NGO0570 3.5 3.4 Possible DNA-binding CreA protein RpoH NGO0618 3.3 2.7 Neisseria-specific protein, uncharacterized DUF331 4.1 7.8 Uncharacterized protein family DUF331; the...”
NMB1336 hypothetical protein from Neisseria meningitidis MC58
Aligns to 12:169 / 182 (86.8%), covers 100.0% of PF02622, 158.5 bits
BP0319 putative transcriptional regulator from Bordetella pertussis Tohama I
Aligns to 31:188 / 201 (78.6%), covers 98.7% of PF02622, 156.1 bits
- Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic
Moon, Microbiology spectrum 2021 - “...family member], BP3239 and BP2878 [putative LysR family members], brpL [an ECF sigma factor], and BP0319 [a putative regulator]) based on our previous observation that the BvgAS regulon controls dozens of proteins involved in transcription ( 24 ). Our list also included 3 classic vrgs (...”
- The BvgAS Regulon of Bordetella pertussis
Moon, mBio 2017 - “...but were previously identified as vag s in Bordetella species ( TableS5 ). These included BP0319, BP0498, BP1590, BP2399, BP2878, BP2981, and BP3239 ( 9 ). Thus, together with the previous microarray studies, our work reveals that the expression of dozens of transcriptional regulators is upregulated...”
FTA_1286 hypothetical protein from Francisella tularensis subsp. holarctica FTA
Aligns to 14:177 / 194 (84.5%), covers 97.5% of PF02622, 144.8 bits
FTL_1216 hypothetical protein from Francisella tularensis subsp. holarctica
Q2A303 UPF0301 protein FTL_1216 from Francisella tularensis subsp. holarctica (strain LVS)
Aligns to 14:177 / 194 (84.5%), covers 97.5% of PF02622, 144.7 bits
wcw_1223 YqgE/AlgH family protein from Waddlia chondrophila WSU 86-1044
Aligns to 19:173 / 189 (82.0%), covers 100.0% of PF02622, 143.2 bits
- Regulatory (pan-)genome of an obligate intracellular pathogen in the PVC superphylum
de, The ISME journal 2016 - “...shows a remarkable degree of sequence conservation (>70% identity in some cases, Figure 1 ). Wcw_1223 is present within the PVC and in several representatives of the Bacteroidetes phylum, albeit with a significantly lower (ca. 35%) sequence identity level. By contrast, the paralogues of the bifunctional...”
- “...observed a peak in the steady-state levels of the dnaA1 , phoB , parB , wcw_1223 , hrcA , dnaA3 and ytgC transcripts in mid-phase (1624h p.i., Figures 2a and b ). By contrast, the nrdR transcript levels are high at 3h and 8h p.i. (...”
Q8EZZ1 Transcriptional regulator from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
LA_3710 putative transcriptional regulator from Leptospira interrogans serovar lai str. 56601
Aligns to 14:166 / 182 (84.1%), covers 96.8% of PF02622, 138.6 bits
CTL0463 hypothetical protein from Chlamydia trachomatis 434/Bu
Aligns to 19:173 / 189 (82.0%), covers 100.0% of PF02622, 135.8 bits
- Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor
Huang, Frontiers in microbiology 2021 - “...Supplementary Table S2 ). Furthermore, RNA-Seq detected significant downregulated expression of ctl0818 (ATP-dependent helicase) and ctl0463 (putative transcriptional regulator of the AlgH/UPF0301 family; Supplementary Table S2 ). Coupled with our detection of altered sigma factor-encoding gene expression, these findings suggest that alterations in transcription initiation, elongation,...”
- “...are presumed 66 target genes, are downregulated is unclear. Several additional putative transcriptional regulators (e.g., CTL0463, CTL0487, and CTL0818) also undergo expression changes in response to heat shock, yet the function of these transcription factors in C. trachomatis remains unclear. The potential mechanisms of differential 54...”
CPSIT_RS03140 YqgE/AlgH family protein from Chlamydia psittaci 6BC
Aligns to 19:173 / 189 (82.0%), covers 100.0% of PF02622, 130.3 bits
MSMEG_6921 hypothetical protein from Mycobacterium smegmatis str. MC2 155
Aligns to 28:184 / 201 (78.1%), covers 97.5% of PF02622, 120.5 bits
- A complex regulatory network controlling intrinsic multidrug resistance in Mycobacterium smegmatis
Bowman, Molecular microbiology 2014 - “...least five-fold underrepresented under MMC exposure ( Table S1 ). Three putative regulatory proteins, MSMEG_5437, MSMEG_6921 and MSMEG_2538 encoding a predicted serine-threonine kinase, a conserved hypothetic regulator, and a MarA-like transcription factor respectively are of particular interest as potential components of a genotoxic stress-responsive pathway (...”
- “...MitomycinC and antibiotics (a) Ten fold dilutions of gene replacement mutants in MSMEG_2538, MSMEG_5437 and MSMEG_6921 were spotted on Middlebrook 7H10 containing 30ng/ml of MMC with MSMEG_5437 being the most sensitive of the mutants. (b) Ten fold serial dilutions of wild type and mc 2 155:5437...”
P9WFK5 UPF0301 protein Rv0038 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Rv0038 hypothetical protein from Mycobacterium tuberculosis H37Rv
Aligns to 29:185 / 202 (77.7%), covers 97.5% of PF02622, 118.2 bits
- The unfoldase ClpC1 of Mycobacterium tuberculosis regulates the expression of a distinct subset of proteins having intrinsically disordered termini
Lunge, The Journal of biological chemistry 2020 (secret) - Computational Identification of the Proteins Associated With Quorum Sensing and Biofilm Formation in Mycobacterium tuberculosis
Hegde, Frontiers in microbiology 2019 - “...Tig, Rv0199, Rv0359, Rv1258c, Rv2136c, Rv3312A, SapM, SecA2, SugA, SugB, SugC Conserved hypotheticals 14 Rv0021c, Rv0038, Rv0566c, Rv0574c, Rv1176c, Rv1354c, Rv1357c, Rv1991c, Rv1996, Rv2216, Rv2298, Rv2300c, Rv3237c, Rv3519 Information pathways 9 Fmt, HelY, Hns, Mfd, MutT3, NrdH, RplM, SigB, TypA Intermediary metabolism and respiration 29 AckA,...”
- “..., are moderately conserved in other genomes but well-conserved within mycobacteria. Also, genes such as Rv0038 , Rv1354c , and Rv0467 are selectively present in mycobacteria and Gram-negative bacteria. The homologs of Rv0566c , narL , ftsH , crp , and mprA are absent in the...”
AT1G33780 hypothetical protein from Arabidopsis thaliana
Aligns to 148:311 / 325 (50.5%), covers 96.2% of PF02622, 111.3 bits
Q6NEA9 YqgE/AlgH family protein from Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Aligns to 25:181 / 198 (79.3%), covers 98.7% of PF02622, 99.4 bits
- Solution structure and properties of AlgH from Pseudomonas aeruginosa
Urbauer, Proteins 2015 - “...to 58% (32% identical, 26% strongly similar). One of the proteins is a Gram-positive protein (Q6NEA9, from Corynebacterium diptheria ), and its sequence shows less similarity to the others, ranging from 42% (20% identical, 22% similar) to 37% (20% identical, 17% similar). The results of the...”
AT3G29240 hypothetical protein from Arabidopsis thaliana
Aligns to 143:310 / 317 (53.0%), covers 96.2% of PF02622, 88.6 bits
AT3G19780 hypothetical protein from Arabidopsis thaliana
Aligns to 914:1057 / 1059 (13.6%), covers 79.6% of PF02622, 49.2 bits
Or search for genetic data about PF02622 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory