Family Search for PF03690 (UPF0160)

PF03690 hits 19 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

MYG1_MOUSE / Q9JK81 MYG1 exonuclease; Protein Gamm1; EC 3.1.-.- from Mus musculus (Mouse) (see 3 papers)
NP_068359 MYG1 exonuclease precursor from Mus musculus
Aligns to 45:365 / 380 (84.5%), covers 99.7% of PF03690, 459.0 bits

• function: 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk (PubMed:31081026). In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (PubMed:31081026).
  disruption phenotype: Mutants are vital, fertile and display no gross abnormalities. They show an inconsistent pattern of altered anxiety- like behavior. Mutant males are significantly less anxious than their wild-type littermates, females show increased anxiety in the locomotor activity arena.
• The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner.
  Tarafdar, Redox biology 2022
  • “...Q8BJW6 Eukaryotic translation initiation factor 2A Eif2a 0.0116343 Q69ZR2 E3 ubiquitin-protein ligase HECTD1 Hectd1 0.0119589 Q9JK81 MYG1 exonuclease Myg1 0.0143308 Q9CQJ6 Density-regulated protein Denr 0.0216944 Q9DBR3 Armadillo repeat-containing protein 8 Armc8 0.0220314 Q91YR5 eEF1A lysine and N-terminal methyltransferase EEF1A 0.0232695 Q8K2H2 Deubiquitinase OTUD6B Otud6b 0.0249278 Q8CFI0...”
• Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.
  Ma, Pharmacology research & perspectives 2020
  • “...specific acylCoA dehydrogenase AFTGFIVEADTPGIHIGKK 1.2 K236 P99028 Cytochrome bc1 complex subunit 6 EHCEQLEKCVK 1.1 K40 Q9JK81 UPF0160 protein MYG1 GGCPWKEHLYHLESELSPK 1.1 K272 Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha IEAACFATIKDGK 1.1 K339 Q61425 Hydroxyacylcoenzyme A dehydrogenase TFESLVDFCKTLGK 1.1 K202 John Wiley & Sons, Ltd 4 DISCUSSION In...”
• Differential proteomic analysis of the pancreas of diabetic db/db mice reveals the proteins involved in the development of complications of diabetes mellitus.
  Pérez-Vázquez, International journal of molecular sciences 2014
  • “...+1.63 3 Kallikrein Klk1 P15947 29.495 8 97 37 +1.68 258 Protein MYG1, mitochondrial Myg1 Q9JK81 43.095 7 74 24 +1.81 284 Pancreatic Carboxypeptidase B1 precursor Cpb1 B2RS76 48.041 15 204 48 +2.25 305 Carboxypeptidase A2, pancreatic, isoform CRA_b Cpa2 Q504N0 37.185 10 99 26 +1.98...”
• Anamorsin, a novel caspase-3 substrate in neurodegeneration.
  Yun, The Journal of biological chemistry 2014
• Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing.
  Grover, Nucleic acids research 2019
  • GeneRIF: analysis of the widely conserved dually localized protein Myg1 shows that it has a role as a 3'-5' RNA exonuclease
• Myg1-deficient mice display alterations in stress-induced responses and reduction of sex-dependent behavioural differences.
  Philips, Behavioural brain research 2010 (PubMed)
  • GeneRIF: Myg1 knockout decreases several behavioural differences (anxiety- and stress-related responses) between male and female animals, indicating that Myg1 contributes to the expression of sex-dependent behavioural differences in mice.

F4K000 Metal-dependent protein hydrolase from Arabidopsis thaliana
AT5G41970 hypothetical protein from Arabidopsis thaliana
Aligns to 52:371 / 373 (85.8%), covers 100.0% of PF03690, 458.3 bits

• New Insights on Arabidopsis thaliana Root Adaption to Ammonium Nutrition by the Use of a Quantitative Proteomic Approach
  Coleto, International journal of molecular sciences 2019
  • “...Q93V68 0.0208 0.20 Calcium-dependent lipid-binding family protein AT1G48090 F4HWS2 0.0156 0.29 Metal-dependent protein hydrolase AT5G41970 F4K000 0.0349 3.09 ijms-20-00814-t003_Table 3 Table 3 Individual glucosinolate content (ng mg 1 FW) in roots of A. thaliana plants grown with nitrate or ammonium as sole N source. Aliphatic Glucosinolates...”
• To New Beginnings: Riboproteogenomics Discovery of N-Terminal Proteoforms in Arabidopsis Thaliana
  Willems, Frontiers in plant science 2021
  • “...AT5G03370 Acylphosphatase family Met66 NH 2 /Ac-T AT5G15870 Glycosyl hydrolase family 81 protein Met45 Ac-S AT5G41970 Metal-dependent protein hydrolase Met28 NH 2 -A AT3G10620 Nudix hydrolase homolog 26 (NUDX26) Met56 Ac-ME Phosphorylation AT1G43900 Protein phosphatase 2C family protein Leu61(CTG)->Met NH 2 /Ac-T AT2G23070 Casein kinase II...”
• New Insights on Arabidopsis thaliana Root Adaption to Ammonium Nutrition by the Use of a Quantitative Proteomic Approach
  Coleto, International journal of molecular sciences 2019
  • “...AT5G19820 Q93V68 0.0208 0.20 Calcium-dependent lipid-binding family protein AT1G48090 F4HWS2 0.0156 0.29 Metal-dependent protein hydrolase AT5G41970 F4K000 0.0349 3.09 ijms-20-00814-t003_Table 3 Table 3 Individual glucosinolate content (ng mg 1 FW) in roots of A. thaliana plants grown with nitrate or ammonium as sole N source. Aliphatic...”
• Comparative analysis of a plant pseudoautosomal region (PAR) in Silene latifolia with the corresponding S. vulgaris autosome
  Blavet, BMC genomics 2012
  • “...the A. thaliana genes ESP1 (AT4G22970), BIP1 (AT5G28540), ACBP1 (AT5G53470), and of genes AT5G53500 and AT5G41970. These latter two genes we named PAR1 and PAR2, respectively (Table 2 ). Table 2 Putative genes identified in Silene BAC clones Gene name Found in TAIR accession Putative function...”
  • “...vulgaris AT5G53500 WD-40 repeat family protein Hydrolase phosphatase 41/42 PAR2* S. latifolia / S. vulgaris AT5G41970 Uncharacterized protein Metal dependent 56/70 PAR3 S. latifolia AT3G15000 Uncharacterized protein Plastid developmental protein DAG 54/- SVA1 S. vulgaris AT4G27700 Rhodanese-like domain-containing protein Rhodanese -/71 % identity with A. thaliana...”

Q641W2 MYG1 exonuclease from Rattus norvegicus
Aligns to 46:366 / 381 (84.3%), covers 99.7% of PF03690, 457.3 bits

• Antioxidant, antiapoptotic and amino acid balance regulating activities of 1,7-dihydroxy-3,4,8-trimethoxyxanthone against dimethylnitrosamine-induced liver fibrosis.
  Zheng, PloS one 2017
  • “...4.23 Q07936 Annexin A2 4.12 0.31 Q0D2L3 Agmatinase 0.37 2.57 Q5FVR2 Thymidine phosphorylase 0.29 10.84 Q641W2 UPF0160 protein MYG1 2.70 0.46 Q64648 Cytochrome P450 2C12 7.86 0.12 Q68G41 Enoyl-CoA delta isomerase 1 0.45 2.18 Q6AYC4 Macrophage-capping protein 4.65 0.30 Q6IMY6 Lysosomal acid lipase/cholesteryl ester hydrolase 3.43...”

MYG1_HUMAN / Q9HB07 MYG1 exonuclease; EC 3.1.-.- from Homo sapiens (Human) (see 4 papers)
Aligns to 46:366 / 376 (85.4%), covers 99.7% of PF03690, 455.2 bits

• function: 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk (PubMed:31081026). In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable).
• Localized proteomic differences in the choroid plexus of Alzheimer's disease and epilepsy patients
  Leitner, Frontiers in neurology 2023
  • “...1.6 FBN1 Fibrillin-1 [Cleaved into: Asprosin] P35555 2.04E-05 2.5 Decreased C12orf10 UPF0160 protein MYG1, mitochondrial Q9HB07 7.02E-07 2.2 AKR7A3 Aflatoxin B1 aldehyde reductase member 3 O95154 1.12E-06 3.2 DCTN2 Dynactin subunit 2 Q13561 3.50E-06 1.7 YWHAB 14-3-3 protein beta/alpha P31946 3.94E-06 2.0 EIF3A Eukaryotic translation initiation...”
• Quantitative proteomics analysis of young and elderly skin with DIA mass spectrometry reveals new skin aging-related proteins.
  Ma, Aging 2020
  • “...Q9ULI1 NACHT and WD repeat domain-containing protein 2 NWD2 0.010662 O75787 Renin receptor ATP6AP2 0.00129 Q9HB07 UPF0160 protein MYG1, mitochondrial C12orf10 0.013933 Table 2 List of down-regulated proteins. Category Accession number Description Gene name pvalue Keratin P19012 Keratin, type I cytoskeletal 15 KRT15 0.00985 Q6A163 Keratin,...”
• Oral Glucose Mobilizes Triglyceride Stores From the Human Intestine
  Xiao, Cellular and molecular gastroenterology and hepatology 2019
  • “...Ferritin heavy chain FTH1 0.8959 .0144 Mitochondria/redox Q9BVL4 Selenoprotein O b SELENOO 5.0987 .0002 Mitochondria/redox Q9HB07 UPF0160 protein MYG1; mitochondrial b C12orf10 5.9843 5.8E-16 Mitochondria/redox P22090 40S ribosomal protein S4 b RPS4Y1 6.7537 .0018 Transcription/RNA processing/translation Q9P003 Protein cornichon homolog 4 b CNIH4 7.1618 1.74E-15 Protein...”
• An algorithm-based meta-analysis of genome- and proteome-wide data identifies a combination of potential plasma biomarkers for colorectal cancer.
  Gawel, Scientific reports 2019
  • “...we selected the top nine proteins: PLOD1 (Q02809), P4HA1 (P13674), LCN2 (P80188), GNS (P15586), C12orf10 (Q9HB07), P3H1 (Q32P28), TRIM28 (Q13263), CEACAM5 (P06731), MAD1L1 (Q9Y6D9); (randomized elastic net frequency >0.45; Supplementary Data 1 ; Materials and Methods). We found that the sum of the expression values of...”
  • “...dataset contains only four out of nine selected putative biomarkers: P4HA1 (P13674), LCN2 (P80188), C12orf10 (Q9HB07) and TRIM28 (Q13263). For this reason, we created a new classifier based on the sum of those four tentative CRC biomarkers, which yielded a high classification accuracy for discriminating early...”
• Standardization of a protocol for shotgun proteomic analysis of saliva
  Ventura, Journal of applied oral science : revista FOB 2018
  • “...A0A087WZY1 Uncharacterized protein 40463.03 16.60 A0A087WUV0 Uncharacterized protein 464.85 8.62 E7ESA3 Uncharacterized protein 188.69 18.87 Q9HB07 UPF0160 protein MYG1_ mitochondrial 435.46 12.23 Q9NY84 Vascular non-inflammatory molecule 3 540.71 10.58 Q14508 WAP four-disulfide core domain protein 2 1637.99 33.87 E9PDB0 WD repeat-containing protein 49 424.40 5.02 Q86UP3...”
• Mitochondrial H⁺-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance
  Formentini, Diabetologia 2017
  • “...SV=2 2.14 Others Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial OS= Homo sapiens GN=PPA2 PE=1 SV=2 0.74 Q9HB07 UPF0160 protein MYG1, mitochondrial OS= Homo sapiens GN=C12orf10 PE=1 SV=2 0.44 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS= Homo sapiens GN=PCK2 PE=1 SV=3 1.19 Q5JRX3 Presequence protease, mitochondrial OS= Homo sapiens...”
• Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
  Liu, Marine drugs 2011
  • “...+2.2 11 Purine nucleoside phosphorylase P00491 32.09/6.45 9 23 208 6.4 12 UPF0160 protein MYG1 Q9HB07 42.41/6.25 2 5 73 +3.8 13 Xaa-Pro dipeptidase P12955 54.51/5.64 11 14 199 2.0 14 SPFH domain-containing protein 2 precursor O94905 37.81/5.47 17 6 104 +2.2 15 60S acidic ribosomal...”

Q58DG1 MYG1 exonuclease from Bos taurus
Aligns to 46:366 / 381 (84.3%), covers 99.7% of PF03690, 455.1 bits

• Growth Traits and Sperm Proteomics Analyses of Myostatin Gene-Edited Chinese Yellow Cattle
  Zhao, Life (Basel, Switzerland) 2022
  • “...-Value FC Regulated Q58D96 Isocitrate dehydrogenase [NAD] subunit, mitochondrial GN = IDH3G 0.041 5.28 UP Q58DG1 UPF0160 protein MYG1, mitochondrial GN = MYG1 0.005 4.12 UP P13619 ATP synthase F(0) complex subunit B1, mitochondrial GN = ATP5F1 0.032 0.08 DOWN F1N3R4 Mitochondrial proton/calcium exchanger protein GN...”

B4FTN5 Metal-dependent protein hydrolase from Zea mays
Aligns to 63:382 / 384 (83.3%), covers 99.7% of PF03690, 453.7 bits

• Comparative Proteomic and Physiological Analyses of Two Divergent Maize Inbred Lines Provide More Insights into Drought-Stress Tolerance Mechanisms
  Zenda, International journal of molecular sciences 2018
  • “...1.66 0.0326 Photosynthesis-antenna proteins 2 B4FCG6 Zm00001d004386 9 Uncharacterized protein 9.0 1 1.48 0.0036 3 B4FTN5 100273215 Metal-dependent protein hydrolase 5.7 1 1.45 0.0459 4 B8A3B7 Zm00001d043059 Uncharacterized protein 20.8 3 1.33 0.0278 5 C0P6L9 Zm00001d053377 Uncharacterized protein 40.2 7 1.33 0.0011 Ribosome 6 B4FLE3 100282216...”
• A comparative glycoproteome study of developing endosperm in the hexose-deficient miniature1 (mn1) seed mutant and its wild type Mn1 in maize
  Silva-Sanchez, Frontiers in plant science 2014
  • “...1 0.01 C Spiro, 2002 Q06509 Caffeic acid 3-0-methyltransferase 5.48 39.57 13 10 1 0.30 B4FTN5 Simillar to Protein MYG1, putative from Ricinus communis (B9RYS8) 6.02 42.70 5 4 3 0.01 M 513 B8A3D0 Simillar to Chloroplast heat shock protein 70 from Pennisetum americanum (A4ZYQ0) 4.96...”

G7PHU7 MYG1 exonuclease from Macaca fascicularis
Aligns to 46:366 / 376 (85.4%), covers 99.7% of PF03690, 453.6 bits

• Gingival Exudatome Dynamics Implicate Inhibition of the Alternative Complement Pathway in the Protective Action of the C3 Inhibitor Cp40 in Nonhuman Primate Periodontitis
  Bostanci, Journal of proteome research 2018
  • “...down 0.88 0.23 0.02 4.52 up G7PHH9 * 0.36 2.39 0.16 2.15 0.02 4.55 up G7PHU7 0.03 4.31 down 0.91 0.59 0.03 3.72 up G7PI76 * 0.02 3.95 down 0.87 0.73 0.03 4.69 up G7PIA8 0.53 4.06 0.22 2.60 0.00 6.66 up G7PID3 0.09 2.34 0.74...”

B9RYS8 Protein MYG1, putative from Ricinus communis
Aligns to 52:371 / 373 (85.8%), covers 99.7% of PF03690, 452.6 bits

• A comparative glycoproteome study of developing endosperm in the hexose-deficient miniature1 (mn1) seed mutant and its wild type Mn1 in maize
  Silva-Sanchez, Frontiers in plant science 2014
  • “...5.48 39.57 13 10 1 0.30 B4FTN5 Simillar to Protein MYG1, putative from Ricinus communis (B9RYS8) 6.02 42.70 5 4 3 0.01 M 513 B8A3D0 Simillar to Chloroplast heat shock protein 70 from Pennisetum americanum (A4ZYQ0) 4.96 4.84 87.29 66.47 1.19 1.08 16 10 6 0.05...”

NP_067653 MYG1 exonuclease precursor from Homo sapiens
Aligns to 46:366 / 376 (85.4%), covers 99.7% of PF03690, 452.6 bits

• MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
  Chen, Nature communications 2024
  • GeneRIF: MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
• Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing.
  Grover, Nucleic acids research 2019
  • GeneRIF: analysis of the widely conserved dually localized protein Myg1 shows that it has a role as a 3'-5' RNA exonuclease
• Correlation of increased MYG1 expression and its promoter polymorphism with disease progression and higher susceptibility in vitiligo patients.
  Dwivedi, Journal of dermatological science 2013 (PubMed)
  • GeneRIF: Significant increase in MYG1 mRNA expression was observed in vitiligo patients compared to controls. The MYG1 mRNA expression was increased in patients with active and generalized vitiligo as compared to stable and localized vitiligo.
• Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1.
  Philips, BMC medical genetics 2010
  • GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
  • GeneRIF: Both MYG1 promoter polymorphism and Arg4Gln polymorphism in the mitochondrial signal of Myg1 have an impact on the regulation of the MYG1 gene and promoter polymorphism is related with suspectibility for actively progressing vitiligo.
• Characterization of MYG1 gene and protein: subcellular distribution and function.
  Philips, Biology of the cell 2009 (PubMed)
  • GeneRIF: Human and mouse MYG1 is ubiquitously expressed, with the highest level in the testis.
• MYG1, novel melanocyte related gene, has elevated expression in vitiligo.
  Kingo, Journal of dermatological science 2006 (PubMed)
  • GeneRIF: demonstrates possible role of MYG1 in vitiligo

CNAG_06946 hypothetical protein from Cryptococcus neoformans var. grubii H99
Aligns to 26:346 / 348 (92.2%), covers 99.7% of PF03690, 447.6 bits

• Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients
  Gressler, Frontiers in immunology 2021
  • “...x x No data available RNA binding 0003723 Extracellular vesicle ( 76 ) Hypothetical protein CNAG_06946 39,13 AFR94883 x x x x x No data available No data available Ketol-acid reductoisomerase, mitochondrial 44,34 AFR96043 x x x Ketol-acid reductoisomerase (NADP(+)) 1.1.1.86 branched-chain amino acid biosynthetic process...”

YEY6_YEAST / P40093 MYG1 protein YER156C from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
YER156C Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus from Saccharomyces cerevisiae
Aligns to 16:337 / 338 (95.3%), covers 100.0% of PF03690, 438.0 bits

• APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells
  Singer-Krüger, The FEBS journal 2020 (PubMed)
  • “...by conventional techniques. One of these, the Yer156C protein, is highly conserved but of unknown function. Its human ortholog, melanocyte proliferating...”
  • “...and dermatological diseases. A first characterization of the Yer156C neighborhood reveals an array of proteins linked to proteostasis and RNA binding. Thus, our...”
• Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing
  Grover, Nucleic acids research 2019
  • “...fit in one representative experiment is depicted. Spot assays with yeast knockout for Myg1 ortholog YER156c, displayed a growth defect in minimal medium and on the respiratory carbon source glycerol (Figure 2B , Supplementary Figure S5 ). As cells are required to utilize mitochondrial respiration based...”
  • “...with the wild type human ortholog (hMYG1) that shares 63 per cent identity with the YER156c could rescue the growth defect of myg1 cells (Figure 2E ), suggesting that despite vast differences in the evolutionary history, human counterpart can perform analogous functions in unicellular yeast. This...”
• Cth2 Protein Mediates Early Adaptation of Yeast Cells to Oxidative Stress Conditions
  Castells-Roca, PloS one 2016
  • “...TIF1 UBC8 GLT1 15, 37, 45, 53, 61, 69, 77 SNZ1 SSB2 YDL114W EFT2 HAC1 YER156C MET10 354, 472 YEF3 KTR2 HEF3 YFL032W SSA2 357 PRB1 215 PPT1 TMT1 VTS1 YMR315W OPT1 GLK1 KAP123 a From data in Fig 1 and S1 Table . See Materials...”
• Genome-wide bimolecular fluorescence complementation analysis of SUMO interactome in yeast
  Sung, Genome research 2013
  • “...and y axes, respectively. Fluorescence images are of the representative candidate proteins Rpl34b, Lia1, and Yer156c for self-assembly, class I, and class II, respectively. WT, GG, and VC in the diagram indicate the representative BiFC image obtained from each analysis with the VC-tagged wild-type Smt3, the...”
• Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance
  Gaytán, Frontiers in genetics 2013
  • “...S YNL051W COG5 2.38 Component of conserved oligomeric Golgi complex; functions in protein trafficking S YER156C - 2.31 Putative protein of unknown function YOR304C-A - 2.26 Protein of unknown function S YML071C COG8 2.11 Component of conserved oligomeric Golgi complex; functions in protein trafficking S YLR371W...”
• Identifying responsive modules by mathematical programming: an application to budding yeast cell cycle
  Wen, PloS one 2012
  • “...TVP18 ZPS1 GO: 0000903 8 4 3 5.40e-03 Cell morphogenesis during vegetative growth WHI4 PCL6 YER156C GO: 0000307 11 3 2 5.57e-03 Cyclin-dependent protein kinase holoenzyme complex TPA1 LPP1 AIF1 SLH1 GO: 0042981 6 5 4 5.09e-03 Regulation of apoptosis APM2 GAL10 YFP045W GO: 0030140 13...”
• Discrete dynamical system modelling for gene regulatory networks of 5-hydroxymethylfurfural tolerance for ethanologenic yeast
  Song, IET systems biology 2009
  • “...CLB3 C107 FMO1 C108 SEC1 C109 ENT1 C110 GAL83 C111 YGR111W C112 HIS1 YBR028C DBP2 YER156C ORT1 GRX4 HOM3 C113 BLM10 C114 MET13 ARO8 C115 OPT1 C116 YHL029C C117 ORM2 C118 MVP1 C119 LST4 C120 ADE5,7 C121 DPH5 C122 ITC1 C123 LPD1 C124 DIA1 C125 BUG1...”
• A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p)
  Millson, Eukaryotic cell 2005
  • “...(1); YDR281c (PHM6) (2); YDR319c (2); YDR412w (1); YER156c (2); YHR036w (2); YGR295c (COS6) (2); YIL041w (3); YIL146c (ECM37) (2); YIR030c (DCG1) (1); YIR042c...”
• More

SPAC694.04c conserved eukaryotic protein from Schizosaccharomyces pombe
Aligns to 6:319 / 324 (96.9%), covers 100.0% of PF03690, 427.1 bits

• Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells
  Brault, G3 (Bethesda, Md.) 2016
  • “..., 365 SPAPB1E7. 11 C Schizosaccharomyces specific protein 2.017 2.349 811 a , 325 a SPAC694.04c Conserved eukaryotic protein 2.010 2.336 301 ID, identified; DB, database; WT, wild type; Fe, iron; S, sulfur; PvGal, pyruvic acid 4,6-ketal-linked galactose; UTR, untranslated region; NADH, nicotinamide adenine dinucleotide hydride;...”
• Key function for the CCAAT-binding factor Php4 to regulate gene expression in response to iron deficiency in fission yeast
  Mercier, Eukaryotic cell 2008
  • “...SPAC19A8.07c SPAP14E8.05c SPAC17G8.08c SPAC26F1.14c SPAC694.04c SPAC1039.01 SPBC947.15c SPAC1782.02c SPBC887.17 SPAC1039.02 SPAC1556.03 SPBC12C2.12c SPAC6C3.02c...”

Afu1g08980 UPF0160 domain protein MYG1, putative from Aspergillus fumigatus Af293
Aligns to 16:362 / 364 (95.3%), covers 99.7% of PF03690, 410.9 bits

• Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype
  Jones, mSphere 2021
  • “...NADH-quinone oxidoreductase Afu1g06830 1 Putative 60s acidic ribosomal protein superfamily member Afu1g07440 1 Molecular chaperone Afu1g08980 1 UPF0160 domain protein Afu1g10630 1 Putative S -adenosylmethionine synthetase Afu1g11460 1 Putative 1,3-beta-glucanosyltransferase Afu2g00690 1 Ortholog(s) has glucan 1,4-alpha-glucosidase activity, role in polysaccharide metabolic process and Golgi apparatus, endoplasmic...”

PADG_02343 uncharacterized protein from Paracoccidioides brasiliensis Pb18
C1G2H7 MYG1 protein from Paracoccidioides brasiliensis (strain Pb18)
Aligns to 16:358 / 362 (94.8%), covers 99.7% of PF03690, 400.1 bits

• Effect of Nitrosative Stress on the S-Nitroso-Proteome of Paracoccidioides brasiliensis
  Navarro, Frontiers in microbiology 2020
  • “...118.76 PADG_00451 C1G0R1 Glucose-6-phosphate isomerase 107.41 PADG_06805 C1GHR9 Acyl-CoA dehydrogenase 106.03 BNA5 C1G0F9 Kynureninase 100.76 PADG_02343 C1G2H7 Uncharacterized protein 86.52 PADG_02030 C1G514 Hsp90 co-chaperone Cdc37 74.29 PADG_04949 C1GBE8 Threonine-tRNA ligase 44.00 PADG_07435 C1GJJ9 Uncharacterized protein 35.30 PADG_03325 C1G820 Uncharacterized protein 31.16 PADG_04890 C1GB89 Uncharacterized protein 28.54...”
• Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis
  Borba, PloS one 2018
  • “...Dienelactone hydrolase family protein x PADG_05356 Isochorismatase domain containing protein x PADG_05798 Hypothetical protein x PADG_02343 Hypothetical protein x PADG_02764 Hypothetical protein x PADG_00183 Hypothetical protein x PADG_01867 Hypothetical protein x PADG_04057 Hypothetical protein x PADG_01220 Hypothetical protein x PADG_05239 Hypothetical protein x PADG_00921 Hypothetical protein...”
• Effect of Nitrosative Stress on the S-Nitroso-Proteome of Paracoccidioides brasiliensis
  Navarro, Frontiers in microbiology 2020
  • “...PADG_00451 C1G0R1 Glucose-6-phosphate isomerase 107.41 PADG_06805 C1GHR9 Acyl-CoA dehydrogenase 106.03 BNA5 C1G0F9 Kynureninase 100.76 PADG_02343 C1G2H7 Uncharacterized protein 86.52 PADG_02030 C1G514 Hsp90 co-chaperone Cdc37 74.29 PADG_04949 C1GBE8 Threonine-tRNA ligase 44.00 PADG_07435 C1GJJ9 Uncharacterized protein 35.30 PADG_03325 C1G820 Uncharacterized protein 31.16 PADG_04890 C1GB89 Uncharacterized protein 28.54 PADG_01755...”

C0NQQ6 MYG1 protein from Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
HCBG_05336 MYG1 protein from Histoplasma capsulatum G186AR
Aligns to 16:370 / 371 (95.7%), covers 100.0% of PF03690, 394.7 bits

• Antibody Binding Alters the Characteristics and Contents of Extracellular Vesicles Released by Histoplasma capsulatum.
  Matos, mSphere 2016
• Extracellular Vesicle-Mediated RNA Release in Histoplasma capsulatum
  Alves, mSphere 2019
  • “...Protein HCBG_04452 3R 3R Predicted protein HCBG_04780 5R 5R Bromodomain-containing protein HCBG_04887 MR Predicted protein HCBG_05336 5R UPF0160 domain protein HCBG_05404 3R / 3F Predicted protein HCBG_05580 3R Methyltransferase domain-containing protein HCBG_05638 5R Predicted protein HCBG_05703 5R Conserved hypothetical protein HCBG_05744 5F T-complex protein 1 subunit...”

TGME49_115250 GAMM1 protein, putative from Toxoplasma gondii ME49
2 alignments in 195:597 / 603 (62.5%), covering up to 77.7% of PF03690, 339.1 bits

• Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development
  Miao, Molecular microbiology 2013
  • “...protein, putative PFL0640w conserved Plasmodium protein TGME49_008800 hypothetical protein, conserved PFF1295w conserved protein, unknown function TGME49_115250 melanocyte proliferating gene 1, putative PFC0170c dihydrolipoamide acyltransferase, putative TGME49_119920 dihydrolipoamide branched chain transacylase, E2 subunit, putative PF13_0305 elongation factor 1-alpha TGME49_086420; TGME49_094800 elongation factor 1-alpha, putative; elongation factor 1-alpha,...”

CAB249, CHAB577_0269 MYG1 family protein from Chlamydia abortus S26/3
Aligns to 6:283 / 289 (96.2%), covers 97.2% of PF03690, 157.9 bits

• Data of de novo genome assembly of the Chlamydia psittaci strain isolated from the livestock in Volga Region, Russian Federation
  Feodorova, Data in brief 2020
  • “...FI836_04005 97.64 44 Rossmann fold domain-containing protein 269,053..271,137 CHAB577_0268 FI836_04015 98.94 45 uncharacterized protein 271,285..272,154 CHAB577_0269 FI836_04020 99.01 46 uncharacterized protein 271,285..272,154 CHAB577_0269 FI836_04020 97.00 47 is(5-nucleosyl)-tetraphosphatase 272,151..272,483 CHAB577_0270 FI836_04030 48 C. abortus GN6 CP021996.1 hypothetical protein 262,872..263,816 CEF07_01315 FI836_03985 99.68 49 hypothetical protein 263,821..264,111 CEF07_01320...”
• Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
  Longbottom, PloS one 2019
  • “...24,051 Cyto 10.0 2 25 UC CAB341 Hypo. protein 52,066 Unknown 9.8 2 14/15 UC CAB249 Hypo. Protein 33,571 Cyto 9.7 2 21 UC CAB047 Put. 50S ribosomal protein L2 (rpsB) 31,234 Unknown 8.7 2 20 UC CAB452 nusA 48,739 Cyto 7.4 2 14 UC CAB780...”

CAB1_0263 MYG1 family protein from Chlamydia abortus LLG
Aligns to 6:283 / 289 (96.2%), covers 97.2% of PF03690, 157.5 bits

• Data of de novo genome assembly of the Chlamydia psittaci strain isolated from the livestock in Volga Region, Russian Federation
  Feodorova, Data in brief 2020
  • “...259,678..261,411 CAB1_0254 FI836_03975 98.73 29 hypothetical protein 267,895..269,139 CAB1_0261 FI836_04010 98.95 30 hypothetical protein 271,371..272,240 CAB1_0263 FI836_04025 98.30 31 hypothetical protein 272,614..274,230 CAB1_0265 FI836_04035 98.82 32 hypothetical protein 272,614..274,230 CAB1_0265 FI836_04035 96.59 33 putative sodium symporter 274,832..276,166 CAB1_0267 FI836_04045 96.55 34 C. abortus GIMC 2006: CabB577...”

CTL0642 hypothetical protein from Chlamydia trachomatis 434/Bu
CT386 predicted metal dependent hydrolase from Chlamydia trachomatis D/UW-3/CX
Aligns to 6:284 / 289 (96.5%), covers 97.2% of PF03690, 154.5 bits

• Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer
  LaBrie, mBio 2019
  • “...53 nt upstream pgi d ctl0639 / 0640 ( ct383 / 384 ) Converging 755990 ctl0642 / 0643 ( ct386 / 387 ) Diverging 759051 218/69 nt upstream of hypothetical proteins ctl0647 / 0648 ( ct391 / 392 ) Converging 765276 ctl0682 / 0683 ( ct423...”
• Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer
  LaBrie, mBio 2019
  • “...d ctl0639 / 0640 ( ct383 / 384 ) Converging 755990 ctl0642 / 0643 ( ct386 / 387 ) Diverging 759051 218/69 nt upstream of hypothetical proteins ctl0647 / 0648 ( ct391 / 392 ) Converging 765276 ctl0682 / 0683 ( ct423 / 424 ) Shared...”
• Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection
  Pickering, Scientific reports 2017
  • “...1.78 1 Positive CT288 12 12.55 1.88 0 Positive CT359 8 5.55 1.83 1 Positive CT386 7 7.75 2.07 0 Positive CT394 hrcA 15 0.73 2.01 0 Purifying CT414 pmpC 41 2.88 1.52 16 Purifying CT442 crpA 28 0.86 2.52 17 Purifying CT456 tarP 32 6.84...”
• Identification of Chlamydia trachomatis Antigens Recognized by T Cells From Highly Exposed Women Who Limit or Resist Genital Tract Infection
  Russell, The Journal of infectious diseases 2016
  • “...CT319 rI11 50S ribosomal protein L11 0.273 3.03 .052 CT386 . . . Metal dependent hydrolase 0.273 3.42 .054 CT130a glnQ ABC amino acid transporter ATPase 0.455...”
• Identification of type III secretion substrates of Chlamydia trachomatis using Yersinia enterocolitica as a heterologous system
  da, BMC microbiology 2014
  • “...CT053, CT080, CT105, CT142, CT143, CT144, CT153, CT161, CT172, CT273, CT277, CT289, CT309, CT330, CT338, CT386, CT425, CT568, CT583, CT590, CT631, CT635, CT656, CT696, CT702, CT837, CT845, and CT849; we used the nomenclature of the annotated C. trachomatis D/UW3 strain [ 53 ]; the names of...”
• The alternative translational profile that underlies the immune-evasive state of persistence in Chlamydiaceae exploits differential tryptophan contents of the protein repertoire
  Lo, Microbiology and molecular biology reviews : MMBR 2012
  • “...its genome (79). These are CT067, CT175, CT253, CT381, CT386, CT444, CT541, CT548, CT567, CT600, CT734, CT770, CT775, and CT780. One of these (omp3; CT444),...”

Or search for genetic data about PF03690 in the Fitness Browser