Family Search for PF03891 (DUF333)
PF03891 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
HMPREF0010_01099 I78 family peptidase inhibitor from Acinetobacter baumannii
D0C8L9 Hemolysin from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)
A1S_1321 putative hemolysin from Acinetobacter baumannii ATCC 17978
Aligns to 31:77 / 144 (32.6%), covers 95.8% of PF03891, 82.7 bits
- Loss of Lipooligosaccharide Synthesis in Acinetobacter baumannii Produces Changes in Outer Membrane Vesicle Protein Content
Cano-Castaño, International journal of molecular sciences 2024 - “...mucD Periplasmic serine endoprotease DegP-like 1.84 <0.01 D0C608 HMPREF0010_00188 DJ-1/PfpI family protein 1.83 <0.01 D0C8L9 HMPREF0010_01099 Hemolysin 1.79 0.01 D0CDA9 HMPREF0010_02739 Uncharacterized protein 5.62 <0.01 D0CBW9 HMPREF0010_02249 Uncharacterized protein 3.44 <0.01 D0CFX4 HMPREF0010_03654 Uncharacterized protein 2.86 <0.01 D0C5H7 HMPREF0010_00007 Uncharacterized protein 2.05 0.01 II. Underexpressed proteins...”
- Loss of Lipooligosaccharide Synthesis in Acinetobacter baumannii Produces Changes in Outer Membrane Vesicle Protein Content
Cano-Castaño, International journal of molecular sciences 2024 - “...B-cell epitopes. Another lipoprotein, a hemolysin, and a DJ-1/PfpI family protein contained four epitopes (D0C608; D0C8L9; D0CDU8). Two proteins with unknown location had five epitopes (D0CDW1; D0C5N9), and one uncharacterized protein had six epitopes (D0CBW9). Seven epitopes were present in the toluene tolerance protein Ttg2D (D0CCX7)....”
- “...D0CBP8 mucD Periplasmic serine endoprotease DegP-like 1.84 <0.01 D0C608 HMPREF0010_00188 DJ-1/PfpI family protein 1.83 <0.01 D0C8L9 HMPREF0010_01099 Hemolysin 1.79 0.01 D0CDA9 HMPREF0010_02739 Uncharacterized protein 5.62 <0.01 D0CBW9 HMPREF0010_02249 Uncharacterized protein 3.44 <0.01 D0CFX4 HMPREF0010_03654 Uncharacterized protein 2.86 <0.01 D0C5H7 HMPREF0010_00007 Uncharacterized protein 2.05 0.01 II. Underexpressed...”
- Using comparative genomics to understand molecular features of carbapenem-resistant Acinetobacter baumannii from South Korea causing invasive infections and their clinical implications
Kim, PloS one 2020 - “...22(100) 1 50(92.6) 39(88.6) 0.37 A1S_1180 46(10) 13(100) 1 37(100) 22(100) 1 54(100) 44(100) 1 A1S_1321 45(97.8) 13(100) 0.78 36(97.3) 22(100) 0.63 53(98.1) 44(100) 0.55 A1S_1386 46(10) 13(100) 1 37(100) 22(100) 1 54(100) 44(100) 1 A1S_1510 46(10) 13(100) 1 37(100) 22(100) 1 53(98.1) 44(100) 0.55 A1S_1921...”
- Identification of novel regulatory small RNAs in Acinetobacter baumannii
Sharma, PloS one 2014 - “...of AbsR25 sRNA predicted by bioinformatic approaches is 333 nts and the location is between A1S_1321 and A1S_1322 genes, encoding putative hemolysin and dihydro-dipicolinate synthetase respectively. Northern blotting and RACE mapping showed that the transcript of AbsR25 sRNA was about 164 nts ( Figure S1 )....”
- Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles
Jin, PloS one 2011 - “...( n =57). Virulence-associated proteins, including AbOmpA, CsuA/B (A1S_2218), CsuC (A1S_2215), CsuD (A1S_2214), putative hemolysin (A1S_1321), putative serine protease (A1S_2525), Cu/Zn superoxide dismutase (A1S_3143), fimbrial protein (A1S_1510), bacterioferritin (A1S_3175), RND superfamily transporter (A1S_0116), putative RND type efflux pump (A1S_0009), and putative protease (A1S_2470), were found in...”
ABAYE2389 hypothetical protein from Acinetobacter baumannii AYE
Aligns to 31:77 / 144 (32.6%), covers 95.8% of PF03891, 80.6 bits
ABUW_2554 I78 family peptidase inhibitor from Acinetobacter baumannii
Aligns to 31:77 / 144 (32.6%), covers 95.8% of PF03891, 80.6 bits
VCA0594 hemolysin from Vibrio cholerae O1 biovar eltor str. N16961
B1B1N2 Hemolysin from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Aligns to 43:89 / 93 (50.5%), covers 100.0% of PF03891, 78.6 bits
- Structural and Proteomic Changes in Viable but Non-culturable Vibrio cholerae
Brenzinger, Frontiers in microbiology 2019 - “...these, only the putative hemolysin secretion protein VC0199, a putative hemolysin (VC0578), the hemolysin Hlx VCA0594 and the T2SS proteins EpsCEFGL were found with a slightly increased abundance in VBNC cells ( Figure 4 ). Figure 4 Relative protein abundances of proteins associated with pathogenicity. Depicted...”
- A bistable switch and anatomical site control Vibrio cholerae virulence gene expression in the intestine
Nielsen, PLoS pathogens 2010 - “...tcpP (VC0826), hapR (VC0583), tcpH (VC0827), toxS (VC0983), cyaA (VC0122), hapA (VCA0865), hlyA (VCA00219), hlx (VCA0594), cheA1 (VC1397), cheA2 (VC02063), cheA3 (VCA1095) and rrnB (E. coli b3968). Supporting Information Figure S1 V. cholerae rpoS fails to down regulate tcpA expression and to detach from epithelium. The...”
- The Vibrio cholerae flagellar regulatory hierarchy controls expression of virulence factors
Syed, Journal of bacteriology 2009 - “...activity (14); an additional hemolysin gene (hlx; VCA0594) (45); the gene encoding the chitin-binding protein GbpA (VCA0811), which mediates binding to...”
- “...are upregulated in the flagellar mutants: VCA0218, VCA0219, and VCA0594 (Fig. 2B; see also Table S1 in the supplemental material). VCA0219 encodes the "El Tor"...”
- Comprehensive in silico analyses of fifty-one uncharacterized proteins from Vibrio cholerae
Basu, PloS one 2024 - “...BIBIN2 BIBIN2 BIBIN2 Q9KU58 Q9KNG0 BIBIN2 Q9KL81 Q9KL73 Q9KL73 Q9KPP0 Q9KSJ4 Q9KL81 Q9KL73 Q9KPZ1 Q9KPZ1 B1B1N2 Q9KPZ1 Q9KL73 Q9KNG0 Q9K2J6 Q9KNG0 Q9KPZ1 Q9KS64 Q9KPZ1 Q9KNI6 Q9KN40 Q9K9I6 Q9KVT0 Q9KVW5 Q9KVT0 Q9KL81 Q9KPA0 Q9KL73 Q9KNG0 Q9KSJ4 Q9KPZ1 Q9KNI6 Q9KVT0 Q9KST0 Based on antigenicity, allergenicity, toxicity B-cell and...”
- “...were Q9KRD2 (45), Q9KVG3 (186), Q9KT38 (57), Q9KKL8 (125), Q9KLK5 (70), Q9KND9 (59), Q9KU58 (75), B1B1N2 (55) and Q9KL81 (48) ( S13 Table and S7 Fig ). T-cell epitopes identification The NetCTL servers were used to predict the T-cell epitopes of the proteins. CTL epitopes for...”
YoaF / b1793 DUF333 domain-containing lipoprotein YoaF from Escherichia coli K-12 substr. MG1655 (see paper)
b1793 conserved outer membrane protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 32:78 / 84 (56.0%), covers 100.0% of PF03891, 74.8 bits
- CyuR is a dual regulator for L-cysteine dependent antimicrobial resistance in Escherichia coli
Rodionova, Communications biology 2024 - “...9 ydcP b1435 23S rRNA 5-hydroxycytidine C2501 synthase 40 4.95 GctaAAATaGCcGCcATTTtTCa - - 10 yoaF b1793 Lipoprotein 160 4.92 GGgTAAATgcTgAttATTTAaTC - - 11 dgcP b1794 Diguanylate cyclase 45 4.92 GAtTAAATaaTcAgcATTTAcCC - 1.4 12 zwf b1852 Glucose-6-P dehydrogenase 233 4.61 GAtaAAAaaGTTGttATTTtTTt - 2.8 13 yebK b1853 DNA-binding...”
- Ubiquitin regulatory X (UBX) domain-containing protein 6 is essential for autophagy induction and inflammation control in macrophages
Kim, Cellular & molecular immunology 2024 - “...tlrl-eblps), zymosan (InvivoGen, tlrlzyn), ATP (SigmaAldrich, A5394), nigericin (SigmaAldrich, SML1779), AICAR (SigmaAldrich, A9978), Baf-A1 (SigmaAldrich, b1793), DBeQ (Selleckchem, Houston, TX, USA, S7199), SMER28 (Tocris Bioscience, Bristol, UK, 307538-42-7), and MitoTEMPO (SigmaAldrich, SML0737) were added at the indicated concentrations and times for individual experiments. Bulk RNA-seq and...”
- Chemical mimetics of the N-degron pathway alleviate systemic inflammation by activating mitophagy and immunometabolic remodeling
Silwal, Experimental & molecular medicine 2023 - “...lysed for RNA preparation or Western blotting. For autophagic flux analysis, bafilomycin A1 (BafA1) (SigmaAldrich, b1793) was preincubated with the cells for 1.5h at a final concentration of 100nM. RNA preparation and real-time polymerase chain reaction TRIzol reagent (Invitrogen, Waltham, MA, USA; 15596026) was used for...”
- Folliculin Prevents Lysosomal Degradation of Human Papillomavirus To Support Infectious Cell Entry
Ishii, Journal of virology 2023 (secret) - Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins
Chino, EMBO reports 2022 (secret) - A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2
Wu, 2021 - MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate
Gutierrez-Prat, Proceedings of the National Academy of Sciences of the United States of America 2021 (secret)
STM1275 putative hemolysin from Salmonella typhimurium LT2
SC1286 putative hemolysin from Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Aligns to 31:77 / 83 (56.6%), covers 100.0% of PF03891, 74.2 bits
NMBNZ0533_0823 DUF333 domain-containing protein from Neisseria meningitidis NZ-05/33
Aligns to 23:70 / 71 (67.6%), covers 100.0% of PF03891, 73.3 bits
Z2835 orf, hypothetical protein from Escherichia coli O157:H7 EDL933
Aligns to 32:78 / 84 (56.0%), covers 95.8% of PF03891, 72.7 bits
VPA0257 hemolysin from Vibrio parahaemolyticus RIMD 2210633
FORC22_3317 DUF333 domain-containing protein from Vibrio parahaemolyticus
Aligns to 33:79 / 86 (54.7%), covers 97.9% of PF03891, 72.3 bits
- iTRAQ-based proteomic profiling of Vibrio parahaemolyticus under various culture conditions
Yang, Proteome science 2015 - “...11 general secretion pathway proteins. Other virulence related proteins such as three hemolysins(GN VP0730, VP2536, VPA0257) and regulator proteins Hfq and rsmA were also significantly identified. Protein quantification and differentiation analysis Proteins with iTRAQ ratios <0.50 or >2.0, p <0.05 were considered significantly different in protein...”
- “...this study. Three hemolysin proteins including putative hemolysins (GN VP0730, GN VP2536) and hemolysin (GN VPA0257) were identified, although TDH production was reported to be affected by environmental factors, such as pH, temperature, and chemicals [ 40 , 41 ], but significant differences in abundance have...”
- Potential Survival and Pathogenesis of a Novel Strain, Vibrio parahaemolyticus FORC_022, Isolated From a Soy Sauce Marinated Crab by Genome and Transcriptome Analyses
Chung, Frontiers in microbiology 2018 - “...ORFs encoding various hemolysin genes (FORC22_0344, FORC22_0414, FORC22_1716, FORC22_2576, and FORC22_3059 in chromosome I; FORC22_3287, FORC22_3317, and FORC22_3346 in chromosome II) were detected; these genes may be responsible for the virulence of the FORC_022 strain. In addition, various secretion systems including types I, II, III, IV,...”
NGO0350 hypothetical protein from Neisseria gonorrhoeae FA 1090
Aligns to 23:70 / 71 (67.6%), covers 97.9% of PF03891, 71.2 bits
HVX45_RS04205 DUF333 domain-containing protein from Escherichia fergusonii
Aligns to 32:78 / 85 (55.3%), covers 100.0% of PF03891, 65.9 bits
- OrthoRefine: automated enhancement of prior ortholog identification via synteny
Ludwig, BMC bioinformatics 2024 - “...GV529_RS05870 and SOG19.1 which consisted of b3271, HVX45_RS11505, & GV529_RS14465, while excluding b4106, b4096, HVX45_RS02390, HVX45_RS04205, & HVX45_RS09410 as presumed paralogs (Fig. 4 ). The BLAST e-values and percent identity from OrthoFinders alignment supported the presence of these two natural subgroups in HOG19 (Additional file 2...”
M892_26640 DUF333 domain-containing protein from Vibrio campbellii ATCC BAA-1116
Aligns to 33:79 / 86 (54.7%), covers 95.8% of PF03891, 65.6 bits
- Vibrio campbellii hmgA-mediated pyomelanization impairs quorum sensing, virulence, and cellular fitness
Wang, Frontiers in microbiology 2013 - “...protein Hfq 1.46E-06 2.94 1.96 1.50 R M892_18180 Ecotin precursor 6.37E-05 1.51 0.99 1.53 R M892_26640 Hemolysin 6.13E-08 1.93 0.54 3.57 R M892_05800 Lipoprotein-related protein 6.13E-08 1.20 0.24 5.00 S M892_08695 Hypothetical protein 3.42E-05 1.09 0.40 2.73 S M892_13325 Hypothetical protein 4.02E-07 3.90 1.96 1.99 S...”
- “...down-regulation of several virulence factors in hmgA . However, with the exception of two [hemolysin (M892_26640) and azurin (M892_25430)], the genes encoding these factors were not differentially expressed suggesting that the decreased virulence potential of hmgA was not caused by an overt down-regulation of accepted virulence...”
YdbJ / b4529 DUF333 domain-containing protein YdbJ from Escherichia coli K-12 substr. MG1655 (see paper)
UTI89_C1621 hypothetical protein from Escherichia coli UTI89
b4529 hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 37:84 / 88 (54.5%), covers 95.8% of PF03891, 53.1 bits
- Genetic requirements for uropathogenic <i>E. coli</i> proliferation in the bladder cell infection cycle
Mediati, mSystems 2024 - “...synthase (arginine/ornithine biosynthesis) 4.81 1.24E-05 7.18E-04 UTI89_C3814 purH Formyltransferase/IMP cyclohydrolase (purine biosynthesis) 4.80 3.29E-03 6.53E-02 UTI89_C1621 Hypothetical protein (DUF333-containing protein) 4.49 4.81E-03 8.12E-02 UTI89_C1620 Hypothetical protein 4.21 9.48E-03 1.26E-01 UTI89_C0037 carB Carbamoyl-phosphate synthase (arginine/pyrimidine biosynthesis) 4.20 3.86E-05 4.38E-03 UTI89_C2877 purL Phosphoribosylformylglycinamide synthetase (purine biosynthesis) 4.19 2.72E-04...”
- Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcripts
Lorenz, Nucleic acids research 2010 - “...cvrA b1191 Sense Predicted cation/proton antiporter 1044 157 1 439 032 1 439 135 ydbJ b4529 Antisense Predicted protein 1277 149 3 199 820 3 199 959 ygiM; cca b3055; b3056 Antisense; antisense Predicted signal transduction protein (SH3 domain); fused tRNA nucleotidyl transferase/23-cyclic phosphodiesterase/2-nt and phosphatase...”
Or search for genetic data about PF03891 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory