Family Search for PF04285 (DUF444)
Running HMMer for PF04285
PF04285 hits 25 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
Q9KQX4 UPF0229 protein VC_1873 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
VC1873 conserved hypothetical protein from Vibrio cholerae O1 biovar eltor str. N16961
VC_1873 YeaH/YhbH family protein from Vibrio cholerae O1 biovar El Tor str. N16961
Aligns to 3:421 / 423 (99.1%), covers 100.0% of PF04285, 641.0 bits
- Comprehensive in silico analyses of fifty-one uncharacterized proteins from Vibrio cholerae
Basu, PloS one 2024 - “...0.994 were observed for the interaction between SpoVR family protein, Q9KQX3 and a hypothetical protein, Q9KQX4 (VC_1873) and uncharacterized protein, Q9KQX5 (VC_1872) respectively. Other interaction with high confidence score of 0.993 was seen in PPI between EAL domain containing Q9KRD2 and Q9KPJ7 (Gene name- VC_2370) which...”
- Emergence of multidrug resistant, ctx negative seventh pandemic Vibrio cholerae O1 El Tor sequence type (ST) 69 in coastal water of Kerala, India
Ayyappan, Scientific reports 2024 - “...AE003852.1). The gene identified in pathogenicity island 1 (VC0819, VC0827, and VC0847), pathogenicity Island 2 (VC1873, VC 1776, VC1758, VC1790, VC1765, VC1809, VC1760) and pandemic island 1 (VC0175, VC0178, VC0180, VC0183, VC0185) were shown 100% identity with V. cholerae strain N16961 strain (Accession No: AE003852.1). However,...”
- Comprehensive in silico analyses of fifty-one uncharacterized proteins from Vibrio cholerae
Basu, PloS one 2024 - “...were observed for the interaction between SpoVR family protein, Q9KQX3 and a hypothetical protein, Q9KQX4 (VC_1873) and uncharacterized protein, Q9KQX5 (VC_1872) respectively. Other interaction with high confidence score of 0.993 was seen in PPI between EAL domain containing Q9KRD2 and Q9KPJ7 (Gene name- VC_2370) which is...”
VP0986 conserved hypothetical protein from Vibrio parahaemolyticus RIMD 2210633
Aligns to 3:421 / 423 (99.1%), covers 100.0% of PF04285, 635.3 bits
- Transcriptome analysis of Vibrio parahaemolyticus in type III secretion system 1 inducing conditions
Nydam, Frontiers in cellular and infection microbiology 2014 - “...44.4 48.8 69.4 88.9 130.2 vp0985 SpoVR family protein COG2719S 3.1 9.8 12.9 18.0 32.1 vp0986 Hypothetical protein COG2718S 2.1 11.3 15.3 25.5 40.7 vp0987 Hypothetical protein 2.4 9.4 12.7 25.1 29.1 vp1012 Cold shock-like protein CspD COG1278K 7.3 21.6 31.9 42.5 70.0 vp1205 Hypothetical protein...”
- “...have a connection with T3SS1 is unclear at present. Several genes encoding hypothetical proteins ( vp0986 , vp0987 , vp1205 , vp1605 , vp2070 , vp2910 , vpa0669 , vpa0694 , vpa1050 , vpa1387 , vpa1388 , vpa1391 , vpa1396 , vpa1398 ), a SpoVR family...”
VDA_001579 YeaH/YhbH family protein from Photobacterium damselae subsp. damselae CIP 102761
Aligns to 3:421 / 423 (99.1%), covers 100.0% of PF04285, 631.4 bits
ECs2493 hypothetical protein from Escherichia coli O157:H7 str. Sakai
Aligns to 3:421 / 427 (98.1%), covers 99.8% of PF04285, 630.4 bits
b1784 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) from Escherichia coli BW25113
YeaH / b1784 DUF444 domain-containing protein YeaH from Escherichia coli K-12 substr. MG1655 (see 3 papers)
b1784 hypothetical protein from Escherichia coli str. K-12 substr. MG1655
P76235 UPF0229 protein YeaH from Escherichia coli (strain K12)
Aligns to 3:421 / 427 (98.1%), covers 99.8% of PF04285, 630.4 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
- Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes
Santos-Zavaleta, BMC genomics 2019 - “...GEA, IMP [ 10 ] MSI , [ 11 ] GEA, IMP metabolic process ydhY b1784 ydhY VWXUT FNR (+), NarL (), NarP () + MSI [ 10 ] oxidation-reduction process yeaH b2013 yea G H NtrC (+) + MSI [ 10 ] yeeE b2665 yeeE...”
- 18th Congress of the European Hematology Association, Stockholm, Sweden, June 13–16, 2013
, Haematologica 2013 - Reconfiguring the quorum-sensing regulator SdiA of Escherichia coli to control biofilm formation via indole and N-acylhomoserine lactones
Lee, Applied and environmental microbiology 2009 - “...b1442 b1443 b1444 b1470 b1487 b1536 b1629 b1690 b1729 b1784 b1955 b1967 b2014 b2080 b2112 b2135 b2165 b2660 b2654 b2655 b2658 b2672 b2809 b2856 b2857 b3099...”
- Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states
Fong, Genome research 2005 - “...fliD, y-1 r N-r y n-y N n b1045, b1471, b1784, b2086, b2327, b3293, b1141, b1566, b1836, b2263, b2742, b4078, metU, alaW, thrV, flgN, wrbA, sodC, otsB, yehV,...”
- Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity
Weber, Journal of bacteriology 2005 - “...b1188 b1164 b1258 b1259 b1341 b1547 b1614 b1783 b1784 b1847 b1999 b2080 b2086 b2602 b2660 b2672 b2665 Putative acyl-CoA dehydrogenase (flavoprotein), adaptive...”
- Physiological studies of Escherichia coli strain MG1655: growth defects and apparent cross-regulation of gene expression
Soupene, Journal of bacteriology 2003 - “...to b1444), ddpXABCDE (b1483 to b1488), yeaGH (b1783 to b1784), yedL (b1932), cbl (b1987), nac (b1988), argT (b2310), ygjG (b3073), and glnALG (b3868 to b3870)....”
- Genetic snapshots of the Rhizobium species NGR234 genome
Viprey, Genome biology 2000 - “...28f07 AAC75038 938 21a05 Q45584 885 17d02 P77391 938a 12b10 overlaps clone 21a05 886 24f10 P76235 887 28f08 P76235 Synechocystis sp. 888 28a06 P39338 939 04a01 BAA17151 889 30e08 P08367 940 06c03 BAA17443 890 27c11 P77165 941 04h11 BAA18318 891 02b12 P75844 942 09g07 BAA18319 892...”
STM1284 putative cytoplasmic protein from Salmonella typhimurium LT2
Aligns to 3:422 / 428 (98.1%), covers 99.8% of PF04285, 629.2 bits
- Salmonella serovar identification using PCR-based detection of gene presence and absence
Arrach, Journal of clinical microbiology 2008 - “...STM1055, STM1088, STM1096, STM1130, STM1188, STM1240, STM1284, STM1285, STM1352, STM1360, STM1380, STM1381, STM1525, STM1533, STM1537, STM1540, STM1543,...”
- The Rcs phosphorelay system is specific to enteric pathogens/commensals and activates ydeI, a gene important for persistent Salmonella infection of mice
Erickson, Molecular microbiology 2006 - “...STM1491 STM3443 STM1515 STM1492 STM3363 STM2311 STM2795 STM1589 STM1284 STM4451 STM0615 STM1952 STM0680 flgD flgB tufA rplP cdh osmY +7.83 1.43 +6.42 1.56 +2.64...”
Sama_1922 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) from Shewanella amazonensis SB2B
Aligns to 3:421 / 423 (99.1%), covers 99.8% of PF04285, 627.5 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
SO2883 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) from Shewanella oneidensis MR-1
Aligns to 3:420 / 422 (99.1%), covers 99.8% of PF04285, 623.1 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
PA0587 hypothetical protein from Pseudomonas aeruginosa PAO1
PA14_07660 hypothetical protein from Pseudomonas aeruginosa UCBPP-PA14
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 611.8 bits
- A VirB4 ATPase of the mobile accessory genome orchestrates core genome-encoded features of physiology, metabolism, and virulence of Pseudomonas aeruginosa TBCF10839
Wiehlmann, Frontiers in cellular and infection microbiology 2023 - “...PA0263 hcpC, secreted protein Hcp, part of T6SS 45.2 PA0355 pfpI, intracellular protease PfpI 7.7 PA0587 Conserved hypothetical protein 12.7 PA0630 Hypothetical protein 8.5 PA0692 pdtB, phosphate depletion regulated two-partner secretion partner B, transporter PdtB 6.4 PA0852 cpbD, chitin-binding protein CbpD precursor 14.9 PA0997 pqsB, catalyzes...”
- Identification of novel targets of azithromycin activity against Pseudomonas aeruginosa grown in physiologically relevant media
Belanger, Proceedings of the National Academy of Sciences of the United States of America 2020 (secret) - Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Tan, Antimicrobial agents and chemotherapy 2014 - “...tssF1 rahU aer2 cttP X PA0523 PA0575 PA0586 PA0587 PA0704 PA0707 PA0852 PA1001 PA1027 PA1127 PA1130 PA1131 PA1134 PA1214 PA1215 PA1216 PA1220 PA1221 PA1245...”
- Azithromycin inhibits expression of the GacA-dependent small RNAs RsmY and RsmZ in Pseudomonas aeruginosa
Pérez-Martínez, Antimicrobial agents and chemotherapy 2011 - “...negative effect on the abundance of the PA0586 and PA0587 transcripts in P. aeruginosa. Little is currently known about the functions of the PA0588-PA0584 gene...”
- Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa
Filiatrault, Infection and immunity 2005 - “...PA0179 PA0200 PA0430 PA0433 PA0447 PA0471 PA0472 PA0586 PA0587 PA0747 PA0792 PA0802 PA0836 PA0918 PA0930 PA0997 PA0998 PA0999 PA1000 PA1002 PA1045 PA1052 PA1076...”
- “...PA0513 PA0514 PA0516 PA0518 PA0519 PA0521 PA0526 PA0586 PA0587 PA0614 PA0623 PA0624 PA0627 PA0628 PA0632 PA0633 PA0639 PA0742 PA0743 PA0744 PA0746 PA0747 PA0782...”
- Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide
Salunkhe, Journal of bacteriology 2005 - “...PA0173 PA0174 PA0176 PA0177 PA0178 PA0179 PA0459 PA0586 PA0587 PA0743 PA1041 PA1172 (napC) PA1173 (napB) PA1174 (napA) PA1175 (napD) PA1176 (napF) PA1177 (napE)...”
- MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa
Wu, Journal of bacteriology 2004 - “...PA3158 PA0102 PA2393 PA2717 PA4470 PA5491 #PA0320 PA0586 PA0587 PA0588 PA0613 #PA0737 PA0807 PA0990 PA1245 PA1323 #PA1471 #PA1784 PA1852 PA2159 PA2161 #PA2167...”
- Loss of the Two-Component System TctD-TctE in Pseudomonas aeruginosa Affects Biofilm Formation and Aminoglycoside Susceptibility in Response to Citric Acid
Taylor, mSphere 2019 - “...4.73 PA14_01320 c coIII Cytochrome c oxidase, subunit III 4.51 PA14_60190 clpB ClpB protein 3.81 PA14_07660 3.77 PA14_49130 dctA C 4 -Dicarboxylate transport protein 3.63 PA14_70040 dadA d -Amino acid dehydrogenase, small subunit 3.06 PA14_38840 2.88 PA14_17550 2.82 PA14_07680 2.78 PA14_68840 2.75 PA14_58690 2.68 PA14_61600 2.68...”
Pf6N2E2_4800 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) from Pseudomonas fluorescens FW300-N2E2
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 610.9 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
AO356_14310 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) from Pseudomonas fluorescens FW300-N2C3
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 609.3 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
ETAE_1478 hypothetical protein from Edwardsiella tarda EIB202
Aligns to 3:419 / 423 (98.6%), covers 99.8% of PF04285, 609.0 bits
Pfl01_5140 hypothetical protein from Pseudomonas fluorescens Pf0-1
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 608.7 bits
- Where does the alignment score distribution shape come from?
Ortet, Evolutionary bioinformatics online 2010 - “...Pseudomonas fluorescens Pf-5 and the homologous protein of Pseudomonas fluorescens Pf0-1 (Accession numbers PFL_5654 and Pfl01_5140). Only the second sequence was shuffled 1000 times. Red curve: Gumbel distribution with parameters = 32.25266 and = 5.941174. Blue curve: gamma distribution with parameters = 59.33383 and = 0.601377....”
- “...Pseudomonas fluorescens Pf0-1 Pfl01_4222 922 aa Pseudomonas fluorescens Pf0-1 Pfl01_0838 345 aa Pseudomonas fluorescens Pf0-1 Pfl01_5140 423 aa List of substitution matrices and alignment parameters (Gapo: gap open penalty, Gape: gap extension penaty) Substitution matrices First choice of parameters Second choice of parameters Blosum 62 Gapo:...”
BCAL1664 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 4:418 / 422 (98.3%), covers 100.0% of PF04285, 608.3 bits
PFLU5583 hypothetical protein from Pseudomonas fluorescens SBW25
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 607.8 bits
PFL_5654 Protein of unknown function (DUF444) superfamily from Pseudomonas fluorescens Pf-5
Aligns to 3:421 / 424 (98.8%), covers 99.5% of PF04285, 607.7 bits
- Where does the alignment score distribution shape come from?
Ortet, Evolutionary bioinformatics online 2010 - “...protein in Pseudomonas fluorescens Pf-5 and the homologous protein of Pseudomonas fluorescens Pf0-1 (Accession numbers PFL_5654 and Pfl01_5140). Only the second sequence was shuffled 1000 times. Red curve: Gumbel distribution with parameters = 32.25266 and = 5.941174. Blue curve: gamma distribution with parameters = 59.33383 and...”
PP0396 conserved hypothetical protein from Pseudomonas putida KT2440
Aligns to 20:437 / 440 (95.0%), covers 99.5% of PF04285, 607.4 bits
AO353_07340 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) from Pseudomonas fluorescens FW300-N2E3
Aligns to 3:420 / 423 (98.8%), covers 99.5% of PF04285, 605.2 bits
- mutant phenotype: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
SMc01266 CONSERVED HYPOTHETICAL PROTEIN from Sinorhizobium meliloti 1021
Aligns to 3:431 / 438 (97.9%), covers 99.8% of PF04285, 541.0 bits
- A comparative genomics screen identifies a Sinorhizobium meliloti 1021 sodM-like gene strongly expressed within host plant nodules
Queiroux, BMC microbiology 2012 - “...the N-terminus and a chromate-resistance superfamily domain at the C-terminus. Several other ORFs (SMb20360, SMc01562, SMc01266, SMc03964, and the SMc01424-22 operon) identified in the screen are expressed at a moderate level by bacteria within nodules, but not by free-living bacteria. Conclusions Based on the analysis of...”
- “...of pJH104 GUS marker (may have a polar effect on 3 genes Sma1332,-1331,-1329) SMa1334.original SMa1334.Xsd1 SMc01266 hypothetical protein 438 ORF-disrupting insertion of pJH104 GUS marker (may have a polar effect on 3 gene Smc01265) SMc01266.original SMc01266.Xsd1 greA transcription elongation factor 158 ORF-disrupting insertion of pJH104 GUS...”
- An extracytoplasmic function sigma factor acts as a general stress response regulator in Sinorhizobium meliloti
Sauviac, Journal of bacteriology 2007 - “...smc00795 smc00796 smc00800 smc00885 smc00931 smc01140 smc01266 smc01267 smc01504 smc01505 smc01506 smc01758 smc01814 smc01815 smc01820 smc01933 smc01977...”
- Role of the regulatory gene rirA in the transcriptional response of Sinorhizobium meliloti to iron limitation
Chao, Applied and environmental microbiology 2005 - “...SMc00832 SMc00922 SMc01016 SMc01022 SMc01095 SMc01169 SMc01266 SMc01267 SMc01471 SMc01489 SMc01512 SMc01513 SMc01514 SMc01516 SMc01517 SMc01658 SMc01659...”
- The LuxR homolog ExpR, in combination with the Sin quorum sensing system, plays a central role in Sinorhizobium meliloti gene expression
Hoang, Journal of bacteriology 2004 - “...SMb21523 (minD) SMc03900 (ndvA) SMb20946 (exoY) SMc00912 SMc01266 (hemN) SMc03051 (flbT) SMc04319 SMc03052 (flgD) SMc03072 SMc03031 (flgA) SMb21072 SMb20651...”
RL3273 hypothetical protein from Rhizobium leguminosarum bv. viciae 3841
Aligns to 2:416 / 424 (97.9%), covers 99.8% of PF04285, 516.0 bits
- Factors governing attachment of Rhizobium leguminosarum to legume roots at acid, neutral, and alkaline pHs
Parsons, mSystems 2024 - “...DE 16%*** NE 71% 3/3 RL2969 NE 8%*** NE 16%*** NE 67%** 0/3 (3/3) f RL3273 NE 138% NE 45%* NE 42%*** 1/3 RL3453 d , e DE 30%*** DE 38%** DE 23%*** 3/3 RL3752 ( pssA ) b , c DE 21%*** DE 37%** DE...”
- “...root attachment. Strains made by mutating individual INSeq-identified ES/DE genes pRL100053, pRL110071, pRL110543, RL0109, RL2969, RL3273, RL3453, pckR, and RL4382 were assessed for root attachment ( Table 2 ). Results are shown together with those for the control strains mutated in; pRL100162 ( nifH ) (...”
- Factors governing attachment ofRhizobium leguminosarumto legume roots
Parsons, 2022
CAC0580 Similar to yhbH B.subtilis from Clostridium acetobutylicum ATCC 824
2 alignments in 3:388 / 391 (98.7%), covering up to 48.7% of PF04285, 430.1 bits
- Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum
Ren, BMC genomics 2012 - “...compare to the 824WT (Figure 7 B), including: 11 E -controlled genes prkA (CAC0579), yhbH (CAC0580), spoIIIAA-AH (CAC2093-CAC2086), spoVD (CAC2130); 2 F -controlled genes sigG (CAC1696) and spoIIG (CAC1252); 13 K -controlled genes cotF (CAC0613), cotF- related genes (CAC0614, CAC1335, CAC2615, CAC3317), cotS (CAC2906), cotS -related...”
CPR_1333 Protein of unknown function (DUF444) superfamily from Clostridium perfringens SM101
2 alignments in 3:385 / 392 (97.7%), covering up to 48.4% of PF04285, 422.5 bits
- Genome-Wide Transcriptional Profiling of Clostridium perfringens SM101 during Sporulation Extends the Core of Putative Sporulation Genes and Genes Determining Spore Properties and Germination Characteristics
Xiao, PloS one 2015 - “...ytxC ), CPR_0147 (CD1511), CPR_1448 (CD3032), CPR_2589 (CD3613) CPR_1348 ( ydfR/ydfS ), CPR_2517( yerB ), CPR_1333 ( yhbH ), CPR_1731 ( ymxH ), CPR_1929 ( yunB ), CPR_1626 ( yuzA ), CPR2663 ( yyaC ), CPR2565 ( yyaD/ykvI ), CPR_0309 (CD0546), CPR_1322 (CD1594), CPR_2328 (CD2809), CPR_2525(CD3522),...”
BG05_RS28400 sporulation protein YhbH from Bacillus mycoides
2 alignments in 10:385 / 391 (96.2%), covering up to 47.5% of PF04285, 351.7 bits
YHBH_BACSU / P45742 Stress response UPF0229 protein YhbH from Bacillus subtilis (strain 168) (see paper)
BSU08980 hypothetical protein from Bacillus subtilis subsp. subtilis str. 168
2 alignments in 10:383 / 392 (95.4%), covering up to 45.6% of PF04285, 346.3 bits
- In Silico Safety Assessment of <i>Bacillus</i> Isolated from Polish Bee Pollen and Bee Bread as Novel Probiotic Candidates
Bin, International journal of molecular sciences 2024 - “...protein YhaX O07539 nhaX Stress response protein NhaX O07552 yhbH Stress response UPF0229 protein YhbH P45742 ctc General stress protein CTC P14194 yocK General stress protein 16O P80872 yocM Salt-stress-responsive protein YocM O34321 ysnF Stress response protein YsnF P94560 dps General stress protein 20U P80879 yugI...”
- The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis
Eichenberger, PLoS biology 2004 - “...yfmD (BSU07510), yfnD (BSU07310), yfnE (BSU07300), yfnF (BSU07290), yfnG (BSU07280), yfnH (BSU07270), yhbB (BSU08920), yhbH (BSU08980), yhcO (BSU09160), yhcP (BSU09170), yheC (BSU09780), yheD (BSU09770), yheH (BSU09720), yheI (BSU09710), yhjL (BSU10550), yisZ (BSU10910), yitA (BSU10920), yitB (BSU10930), yitC (BSU10940), yitD (BSU10950), yitE (BSU10960), yjcA (BSU11790), yjcM (BSU11910),...”
GSU3342 conserved domain protein from Geobacter sulfurreducens PCA
Aligns to 238:415 / 447 (39.8%), covers 32.2% of PF04285, 106.2 bits
Or search for genetic data about PF04285 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory