Family Search for PF04286 (DUF445)
PF04286 hits 21 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
O3K_21840 DUF445 domain-containing protein from Escherichia coli O104:H4 str. 2011C-3493
Aligns to 44:418 / 426 (88.0%), covers 99.7% of PF04286, 407.7 bits
YjiN / b4336 DUF445 domain-containing protein YjiN from Escherichia coli K-12 substr. MG1655 (see paper)
b4336 conserved inner membrane protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 44:418 / 426 (88.0%), covers 99.7% of PF04286, 406.2 bits
- Directional RNA-seq reveals highly complex condition-dependent transcriptomes in E. coli K12 through accurate full-length transcripts assembling
Li, BMC genomics 2013 - “...b0050, b0137, b1356, b1382, b1419, b1446, b1457, b1607, b1952, b1998, b3471, b3638, b3937, b4325, b4335, b4336, b4593, b4596, b4610, b4615 and b4620 ) of them were expressed in all the seven samples, suggesting that they are highly likely to be true protein coding genes. Furthermore, 20...”
- Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions
Orth, BMC systems biology 2012 - “...R00367 (F) global orphan R02559 (F) global orphan R02560 (F) global orphan R05623 (F) yjiN (b4336) 0.16 Experimental validation of predicted genes SMILEY and other gap-filling algorithms are useful because they can use a model and existing experimental data to generate predictions. Without performing an experiment...”
c5419 Hypothetical protein yjiN from Escherichia coli CFT073
Aligns to 56:430 / 438 (85.6%), covers 99.7% of PF04286, 402.2 bits
cg0451 hypothetical protein from Corynebacterium glutamicum ATCC 13032
Aligns to 68:431 / 434 (83.9%), covers 99.7% of PF04286, 401.9 bits
- Ciprofloxacin triggered glutamate production by Corynebacterium glutamicum
Lubitz, BMC microbiology 2016 - “...1.38 0.006 cg1937 - Putative secreted protein 1.22 0.015 cg3018 - Hypothetical protein 1.22 0.002 cg0451 - Putative membrane protein 1.21 0.003 cg0712 - Putative secreted protein 1.08 0.014 cg3106 - Conserved hypothetical protein 1.03 0.029 cg2391 aroG 3-Deoxy-7-phosphoheptulonate synthase -1.26 0.022 cg0203 iolE Putative myo-inosose-2...”
Rv0473 POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN from Mycobacterium tuberculosis H37Rv
Aligns to 92:455 / 456 (79.8%), covers 99.7% of PF04286, 400.7 bits
ROD_48251 hypothetical protein from Citrobacter rodentium ICC168
Aligns to 44:417 / 423 (88.4%), covers 99.5% of PF04286, 397.9 bits
- Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux
Petty, PLoS pathogens 2011 - “...in ICC168 ROD_48241 Hypothetical protein pseudo intact C-terminal truncated by 4392 bp deletion in EX-33 ROD_48251 Putative membrane protein absent present 4392 bp deletion in EX-33 ROD_48261 Putative LysR-family transcriptional regulator absent present 4392 bp deletion in EX-33 ROD_48271 Putative transport protein pseudo intact N-terminal truncated...”
- “...protein. The second is a 4392 bp deletion in EX-33 that has deleted two genes (ROD_48251 and ROD_48261) and truncated two other genes (ROD_48241 and ROD_48271) of unknown function. In ICC168, the sequences corresponding to both of these EX-33 deletions are flanked by 2 bp and...”
DIP0375 Putative membrane protein from Corynebacterium diphtheriae NCTC 13129
Aligns to 56:419 / 422 (86.3%), covers 99.7% of PF04286, 390.2 bits
BC1726 hypothetical Membrane Spanning Protein from Bacillus cereus ATCC 14579
BC_1726 DUF445 domain-containing protein from Bacillus cereus ATCC 14579
Aligns to 39:415 / 415 (90.8%), covers 99.5% of PF04286, 313.5 bits
A1S_3369 hypothetical protein from Acinetobacter baumannii ATCC 17978
Aligns to 34:411 / 415 (91.1%), covers 99.2% of PF04286, 276.9 bits
O07543 UPF0754 membrane protein YheB from Bacillus subtilis (strain 168)
Aligns to 12:377 / 377 (97.1%), covers 99.5% of PF04286, 276.9 bits
SERP1382 hypothetical protein from Staphylococcus epidermidis RP62A
Aligns to 12:376 / 376 (97.1%), covers 99.5% of PF04286, 266.5 bits
SE1527 conserved hypothetical protein from Staphylococcus epidermidis ATCC 12228
Aligns to 12:376 / 376 (97.1%), covers 99.5% of PF04286, 265.4 bits
- Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228
Wei, BMC genomics 2006 - “...they code for surface proteins under the pressure of escaping the host immune system. Interestingly, SE1527 and SE0790 are orthologous to surface proteins experimentally identified in one of Group A Streptococcus (GAS) strains (SPY0792 and SPY2018) [ 36 ]. It may also be significant that two...”
- “...conserved hypothetical protein YvcD 3 0 1.0000 0.0440 SE1302 SERP1183 deoxyribonuclease 2 0 1.0000 0.0668 SE1527 SERP1382 conserved hypothetical protein YheB (surface protein) 2 0 1.0000 0.0707 SE2166 SERP2177 glycine betaine aldehyde dehydrogenase gbsA 2 0 1.0000 0.0719 SE2379 SERP0037 cystathionine gamma-synthase 2 0 1.0000 0.0743...”
SA1664 hypothetical protein from Staphylococcus aureus subsp. aureus N315
Aligns to 12:374 / 374 (97.1%), covers 99.5% of PF04286, 250.3 bits
- Mutation of RNA polymerase β-subunit gene promotes heterogeneous-to-homogeneous conversion of β-lactam resistance in methicillin-resistant Staphylococcus aureus
Aiba, Antimicrobial agents and chemotherapy 2013 - “...SA0741 SA0742 SA0761 SA0830 SA1002 SA1049 SA1222 SA1268 SA1664 SA1755 SA2299 SA2491 a b ssl11 sdrC IP-H5/N315IP N315rpoB(N967I)/ N315 Similar to comF operon...”
- Direct targets of CodY in Staphylococcus aureus
Majerczyk, Journal of bacteriology 2010 - “...following genes: SA1042, purQ, SA0788, SA2309, SA1883, SA1664, SA0088, SA0662, SA1042, and SA1883. Three enriched regions are associated with genes...”
- Characterizing the effects of inorganic acid and alkaline shock on the Staphylococcus aureus transcriptome and messenger RNA turnover
Anderson, FEMS immunology and medical microbiology 2010 - “...5 SA1660 hypothetical protein sa_c2805s2371_a_at 4.7 2.5 2.5 SA1663 hypothetical protein sa_c2807s2375_a_at 6.3 ND 2.5 SA1664 hypothetical protein sa_c2851s2417_x_at 3.7 15 5 SA1679 hypothetical protein sa_c8524s7483_a_at 3.6 15 15 SA1680 hypothetical protein sa_c2942s2505_a_at * 4.9 2.5 2.5 SA1705 hypothetical protein sa_c3900s3368_at 17.8 2.5 2.5 SA1986 hypothetical...”
- A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Ender, BMC microbiology 2009 - “...4 or 120 g/ml of cefoxitin fo 0', 10' and 30'. C, Transcriptional profiles of SA1664, SA1665, SA1666 and SA1667 in CHE482 and CHE482, grown to OD 600 nm 0.25 and either uninduced or induced with cefoxitin 4 g/ml for 0', 10' or 30'. Approximate sizes...”
- “...on directly up- and down-stream genes were also investigated. Northern blots of the neighbouring genes SA1664, SA1666 and SA1667, showed that expression of all three genes was very weak compared to that of SA1665. A weak transcript of about 3 kb was present in hybridizations probed...”
- Characterization of the Staphylococcus aureus heat shock, cold shock, stringent, and SOS responses and their effects on log-phase mRNA turnover
Anderson, Journal of bacteriology 2006 - “...SA1033 SA1372 SA1375 SA1438 SA1524 SA1526 SA1664 SA1777 SA2162 SA2218 SA2705 Conserved hypothetical Conserved hypothetical Conserved hypothetical Conserved...”
- “...SA1191 SA1200 SA1375 SA1418 SA1556 SA1658 SA1659 SA1664 SA1670 SA1796 SA1798 SA1810 SA1896 SA1956 SA1972 SA1986 SA2019 SA2033 Conserved hypothetical protein...”
LMOf2365_2257 hypothetical protein from Listeria monocytogenes str. 4b F2365
Aligns to 12:377 / 377 (97.1%), covers 99.7% of PF04286, 248.3 bits
lmo2224 similar to unknown proteins from Listeria monocytogenes EGD-e
Aligns to 12:377 / 377 (97.1%), covers 99.7% of PF04286, 246.7 bits
Y412_SYNY3 / Q55115 UPF0754 thylakoid membrane protein sll0412 from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa) (see paper)
sll0412 unknown protein from Synechocystis sp. PCC 6803
Aligns to 21:416 / 419 (94.5%), covers 98.9% of PF04286, 232.8 bits
FAP1_STRPA / A1C3L3 Fap1 adhesin; Adhesin Fap1; Fimbriae-associated protein Fap1; Serine-rich repeat protein Fap1 from Streptococcus parasanguinis (see 4 papers)
Aligns to 2274:2578 / 2587 (11.8%), covers 66.3% of PF04286, 200.0 bits
- function: The major structural element of fimbriae. Required for adherence to saliva-coated hydroxyapatite beads (SHA), an in vitro tooth model. A Fap1-dependent increase in adherence is seen as the pH is reduced from pH 8 to pH 5.
disruption phenotype: Loss of fimbriae on the cell surface, loss of adherence to saliva-coated hydroxyapatite beads (SAH), an in vitro tooth model. - Serine-rich repeat proteins: well-known yet little-understood bacterial adhesins
Cinar, Journal of bacteriology 2024 (secret) - Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis
Kumar, PloS one 2013 - “...in numbers, include Adhesion A (Q5I6B0) from Fusobacterium nucleatum , Fap1 adhesin (Fimbriae-associated protein Fap1) (A1C3L3) from Streptococcus parasanguis , Malate Synthase (P0A5J4) from M. tuberculosis , YadA (A1JUB7) from Yersinia enterocolitica , Hap from Haemophilus influenza [71] , Lsa21 [103] and LigB from Leptospira interrogans...”
CPE2521 conserved hypothetical protein from Clostridium perfringens str. 13
Aligns to 9:498 / 499 (98.2%), covers 99.5% of PF04286, 194.6 bits
CD0573 putative membrane protin from Clostridium difficile 630
2 alignments in 12:200 / 200 (94.5%), covering up to 35.6% of PF04286, 110.0 bits
- Genome-Wide Transcription Start Site Mapping and Promoter Assignments to a Sigma Factor in the Human Enteropathogen Clostridioides difficile
Soutourina, Frontiers in microbiology 2020 - “..., frr ) ( Sebaihia et al., 2006 ), in envelope-related processes ( cwp27 , CD0573 , lplA, CD3458 ) ( Sebaihia et al., 2006 ), in metabolism ( CD0865 , fdhF, CD0999 , CD1484 and CD2989 ) ( Neumann-Schaal et al., 2019 ) and genes...”
FTN_1270 conserved membrane protein of unknown function from Francisella tularensis subsp. novicida U112
Aligns to 36:162 / 228 (55.7%), covers 20.4% of PF04286, 76.5 bits
VVA1637 conserved hypothetical protein from Vibrio vulnificus YJ016
VV2_1111 Uncharacterized protein conserved in bacteria from Vibrio vulnificus CMCP6
Aligns to 115:234 / 234 (51.3%), covers 25.8% of PF04286, 65.8 bits
- Genotypic diversity and virulence characteristics of clinical and environmental Vibrio vulnificus isolates from the Baltic Sea region
Bier, Applied and environmental microbiology 2013 - “...targeting the flanking regions of PRXII (genes VVA1612 and VVA1637). Strains were considered positive for PRXII when at least three of the four genes on PRXII...”
- Emergence of a virulent clade of Vibrio vulnificus and correlation with the presence of a 33-kilobase genomic island
Cohen, Applied and environmental microbiology 2007 - “...chromosomal flanking genes, VVA1612 in the 5 region and VVA1637 to VVA1639 in the 3 region, were examined to determine their presence among all 67 isolates...”
- “...examined to determine whether VVA1612 is adjacent to VVA1637 in these isolates. The primer pair VVA1612F/VVA1637R, designed within the core 5 and 3 genes,...”
- SOLiD sequencing of four Vibrio vulnificus genomes enables comparative genomic analysis and identification of candidate clade-specific virulence genes
Gulig, BMC genomics 2010 - “...in most clade 2 strains and missing from most clade 1 strains (genes VV2_1090 to VV2_1111 on the CMCP6 genome). They hypothesized that genomic island XII could be responsible for the putative differential virulence of clade 2 strains, evidenced by their association with clinical cases. Table...”
- A consensus sequence for binding of SmcR, a Vibrio vulnificus LuxR homologue, and genome-wide identification of the SmcR regulon
Lee, The Journal of biological chemistry 2008 - “...VV1_1702, VV2_0057 VV2_0058, VV2_0279, VV2_0517, VV2_1111, VV2_1541 VV2_1542 VV2_1543 VV2_1544 VV1_0300, VV1_0840 VV1_0839 VV1_0838 VV1_0837, VV1_1085,...”
- “...VV1_1265 VV1_1471 VV2_0057 VV2_0058 VV2_0279 VV2_0517 VV2_1111 VV2_1541 VV2_1542 VV2_1543 VV2_1544 Hypothetical protein Predicted membrane protein Hypothetical...”
Or search for genetic data about PF04286 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory