Family Search for PF04343 (DUF488)

PF04343 hits 21 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

Msed_0871 protein of unknown function DUF488 from Metallosphaera sedula DSM 5348
Aligns to 10:117 / 129 (83.7%), covers 100.0% of PF04343, 119.1 bits

• Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
  Lewis, mBio 2023
  • “..., and even bacteria. S. acidocaldarius vapB14 and its homolog in the thermoacidophile Metallosphaera sedula (Msed_0871) were both upregulated in biofilm cells, supporting the role of the antitoxin in biofilm regulation. In several Sulfolobales species, including M. sedula, homologs of vapB14 and vapC14 are not colocalized....”
  • “...toxin. To this point, the transcriptional response of the vapB14 homolog in Metallosphaera sedula , Msed_0871, in 3-day-old biofilms and planktonic cultures was consistent with the response of vapB14 in S. acidocaldrius ( Fig.6B ). Since M. sedula Msed_0871 has among the lowest homologies found among...”
• Sessile Lifestyle Offers Protection against Copper Stress in Saccharolobus solfataricus
  Recalde, Microorganisms 2023
  • “...regulation [ 11 ]. S. acidocaldarius vapB14 and its homolog in thermoacidophile Metallosphaera sedula ( msed_0871 ) were both upregulated in biofilm cells, supporting the role of an antitoxin in biofilm regulation [ 11 ]. Recently, it was found that the absence of PolyP impairs biofilm...”

BBMN68_520 DUF488 domain-containing protein from Bifidobacterium longum subsp. longum BBMN68
Aligns to 4:112 / 113 (96.5%), covers 99.2% of PF04343, 118.5 bits

• Transcriptomic analysis of Bifidobacterium longum subsp. longum BBMN68 in response to oxidative shock
  Zuo, Scientific reports 2018
  • “...BBMN68_105 Hypothetical protein 1.92 3.02 BBMN68_248 Hypothetical protein 1.70 2.71 BBMN68_519 Hypothetical protein 1.58 2.39 BBMN68_520 Hypothetical protein 1.92 2.20 BBMN68_1662 a Log 2 ratio represents the ratio of mRNA transcript levels in oxygen-treated samples (30min and 60min) to untreated samples (Cont). b Open reading frame...”

Sca_2018 hypothetical protein from Staphylococcus carnosus subsp. carnosus TM300
SCA_2018 DUF488 domain-containing protein from Staphylococcus carnosus subsp. carnosus TM300
Aligns to 4:117 / 123 (92.7%), covers 100.0% of PF04343, 118.3 bits

• Transcriptomic analysis of staphylococcal sRNAs: insights into species-specific adaption and the evolution of pathogenesis
  Broach, Microbial genomics 2016
  • “...1929303..1929527 SCA_1921 < SCA_1922 84.17 SCAs053 jacL-53 1941508..1941755 opuCA < SCA_1935 515.79 SCAs054 jacL-54 2031863..2032724 SCA_2018 > SCA_2019 7319.06 SCAs055 jacL-55 2088262..2088525 SCA_2075 > SCA_2076 761.4 SCAs056 jacL-56 2199217..2199338 SCA_2172 < SCA_2173 1628.55 SCAs057 jacL-57 2224729..2224907 SCA_2191 < SCA_2192 848.25 SCAs058 jacL-58 2266552..2266687 SCA_2211 > SCAs059...”
• Transcriptomic analysis of staphylococcal sRNAs: insights into species-specific adaption and the evolution of pathogenesis
  Broach, Microbial genomics 2016
  • “...1929303..1929527 SCA_1921 < SCA_1922 84.17 SCAs053 jacL-53 1941508..1941755 opuCA < SCA_1935 515.79 SCAs054 jacL-54 2031863..2032724 SCA_2018 > SCA_2019 7319.06 SCAs055 jacL-55 2088262..2088525 SCA_2075 > SCA_2076 761.4 SCAs056 jacL-56 2199217..2199338 SCA_2172 < SCA_2173 1628.55 SCAs057 jacL-57 2224729..2224907 SCA_2191 < SCA_2192 848.25 SCAs058 jacL-58 2266552..2266687 SCA_2211 > SCAs059...”

BAB2_0759 Protein of unknown function DUF488 from Brucella melitensis biovar Abortus 2308
Q8YBU9 Uroporphyrin-iii c-methyltransferase from Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M)
Aligns to 5:113 / 116 (94.0%), covers 99.2% of PF04343, 118.1 bits

• Endoribonuclease YbeY Is Linked to Proper Cellular Morphology and Virulence in Brucella abortus
  Budnick, Journal of bacteriology 2018
  • “...BAB1_1893 BAB1_2156 (ybeY) BAB2_0223 BAB2_0224 BAB2_0276 BAB2_0732 BAB2_0740 BAB2_0759 BAB2_0847 Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp Hyp...”
• Pan-Proteomic Analysis and Elucidation of Protein Abundance among the Closely Related Brucella Species, Brucella abortus and Brucella melitensis
  Murugaiyan, Biomolecules 2020
  • “...Lipoprotein putative Q2YN45 Probable cytosol aminopeptidase Q2YRJ0 ATP/GTP-binding site motif A (P-loop) Q2YRN7 Uncharacterized protein Q8YBU9 Putative uroporphyrin-iii c-methyltransferase Q2YKY2 Uncharacterized protein Q2YL40 Uncharacterized protein Q2YLM7 Uncharacterized protein Downregulated in B. abortus and Upregulated in B. melitensis Q2YME1 Threonylcarbamoyl-AMP synthase Q2YNW9 Dihydroxy-acid dehydratase Q8YHA5 Glutaryl-CoA dehydrogenase...”

NE2305 conserved hypothetical protein from Nitrosomonas europaea ATCC 19718
Aligns to 14:139 / 182 (69.2%), covers 99.2% of PF04343, 115.3 bits

• Transcriptome of a Nitrosomonas europaea mutant with a disrupted nitrite reductase gene (nirK)
  Cho, Applied and environmental microbiology 2006
  • “...0.180 0.187 0.141 6 5 5 (NE2303) (NE2304) (NE2305) nirB ycaC NAD(P)H nitrite reductase Isochorismatase hydrolase Hypothetical 0.301 0.392 0.380 0.058 0.057...”
  • “...reductase, and its two associated ORFs (NE2304 and NE2305) were down-regulated ca. 2.8-fold in nirK mutant/ wild-type N. europaea. Aside from N assimilation,...”

BCAM2139 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 14:139 / 186 (67.7%), covers 99.2% of PF04343, 115.0 bits

• Response of Burkholderia cenocepacia H111 to micro-oxia
  Pessi, PloS one 2013
  • “...CCE50317 BCAM1926 CBS domain protein 1.2 10.2 CCE53123 BCAM2137 Transcriptional regulatory protein nd 20.0 CCE53121 BCAM2139 Eukaryotic putative RNA-binding region RNP-1 signature nd M only CCE53091 BCAM2167 Hypothetical protein I35_7022 nd 15.6 CCE53041 BCAM2210 Hypothetical protein I35_6972 TM nd M only CCE47618 BCAM2462 Outer membrane protein...”

JQK92_34440 DUF488 family protein from Burkholderia anthina
Aligns to 14:139 / 192 (65.6%), covers 99.2% of PF04343, 112.8 bits

• Genomic adaptation of Burkholderia anthina to glyphosate uncovers a novel herbicide resistance mechanism
  Schwedt, Environmental microbiology reports 2023
  • “...expression? JQK92_21965 Ketoacyl[acylcarrierprotein] synthase family protein C19A Q7K JQK92_28130 Sigma 54interacting transcriptional regulator A38T Q13L JQK92_34440 Downstream of DUF488 domaincontaining protein G55C (55) Altered expression? JQK92_34875 Hypothetical protein C1567 (1567) No protein? a Mutations were identified by genome sequencing. b Mutations were identified by Sanger sequencing....”

SAOUHSC_00202 hypothetical protein from Staphylococcus aureus subsp. aureus NCTC 8325
SA0230 hypothetical protein from Staphylococcus aureus subsp. aureus N315
SAUSA300_0232 hypothetical protein from Staphylococcus aureus subsp. aureus USA300_FPR3757
NWMN_0174 hypothetical protein from Staphylococcus aureus subsp. aureus str. Newman
SACOL0218 hypothetical protein from Staphylococcus aureus subsp. aureus COL
USA300HOU_RS01225 DUF488 domain-containing protein from Staphylococcus aureus subsp. aureus USA300_TCH1516
Aligns to 4:116 / 118 (95.8%), covers 99.2% of PF04343, 112.4 bits

• The Staphylococcus aureus KdpDE two-component system couples extracellular K+ sensing and Agr signaling to infection programming
  Xue, Infection and immunity 2011
  • “...SAOUHSC_02858 SAOUHSC_01296 SAOUHSC_01729 SAOUHSC_01991 SAOUHSC_00202 SAOUHSC_02850 SAOUHSC_03047 SAOUHSC_01032 SAOUHSC_01072 SAOUHSC_00704 SAOUHSC_02886...”
• Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus
  Peng, mSphere 2017
  • “...8.1 Formate acetyltransferase NWMN_0163 SA0219 19.1 Formate-lyase activating enzyme NWMN_0173 SA0229 2.2 7.5 Hypothetical NWMN_0174 SA0230 2.1 16.0 Hypothetical Yes (3.4) NWMN_0175 SA0231 2.2 20.7 Flavohemoprotein Yes (2.9) NWMN_0330 SA0326 8.0 Glyoxalase-like protein NWMN_0331 SA0327 9.2 Luciferase-like monooxygenase NWMN_0332 SA0328 9.2 NADH-dependent flavin mononucleotide (FMN) reductase...”
• Direct targets of CodY in Staphylococcus aureus
  Majerczyk, Journal of bacteriology 2010
  • “...SA1963 SA0010 SA0011 SA2476-SA2471 brnQ2 brnQ1 PTS SA0228 SA0230 Other transporters SA0882 SA0883 SA0884 SA0504 SA0505 SA0506 SA1018 SA1019 SA1038 SA1039 SA1040...”
• Cigarette Smoke Extract-Exposed Methicillin-Resistant Staphylococcus aureus Regulates Leukocyte Function for Pulmonary Persistence
  Kulkarni, American journal of respiratory cell and molecular biology 2016
  • “...SAUSA300_2035 SAUSA300_2138 SAUSA300_1929 SAUSA300_2137 SAUSA300_0232 SAUSA300_0395 SAUSA300_1158 SAUSA300_2360 SAUSA300_0172 SAUSA300_2540 SAUSA300_2418...”
• Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus
  Peng, mSphere 2017
  • “...pflB 8.1 Formate acetyltransferase NWMN_0163 SA0219 19.1 Formate-lyase activating enzyme NWMN_0173 SA0229 2.2 7.5 Hypothetical NWMN_0174 SA0230 2.1 16.0 Hypothetical Yes (3.4) NWMN_0175 SA0231 2.2 20.7 Flavohemoprotein Yes (2.9) NWMN_0330 SA0326 8.0 Glyoxalase-like protein NWMN_0331 SA0327 9.2 Luciferase-like monooxygenase NWMN_0332 SA0328 9.2 NADH-dependent flavin mononucleotide (FMN)...”
• Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus
  Posada, Infection and immunity 2014
  • “...3.70 4.17 2.32 Transcriptional regulators nirR SACOL0218 SACOL1296 SACOL2349 SACOL2732 Transcriptional regulator MarR family member GntR family transcriptional...”
• A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus
  Chen, Molecular microbiology 2009
  • “...-2.2 ABC transporter SACOL0185 -2.5 Peptide ABC transporter SACOL0186 -2.7 Dipeptide ABC transporter, DppClike protein SACOL0218 -2.0 + Conserved hypothetical protein SACOL0219 -2.5 Conserved hypothetical protein SACOL0430 -2.6 Cystathionine -lyase family protein SACOL0431 -2.3 Cystathionine -synthase family protein SACOL0505 -3.1 ABC transporter SACOL0507 -2.3 N-acetylmuramoyl-L-Ala amidase...”
• The Staphylococcus aureus LytSR two-component regulatory system affects biofilm formation
  Sharma-Kuinkel, Journal of bacteriology 2009
  • “...system, mannitol-specific IIBC components fusA infC SACOL0218 SACOL1136 SACOL1802 SACOL2518 SA1472 SACOL2534 SACOL0220 SACOL0778 Description Conserved Conserved...”
• Absence of Protoheme IX Farnesyltransferase CtaB Causes Virulence Attenuation but Enhances Pigment Production and Persister Survival in MRSA
  Xu, Frontiers in microbiology 2016
  • “...Hypothetical protein USA300HOU_RS07065 pstC 2.23 4.71E-03 Phosphate ABC superfamily ATP binding cassette transporter, membrane protein USA300HOU_RS01225 2.26 9.38E-03 Hypothetical protein USA300HOU_RS01665 2.29 2.74E-03 Possible CNT family concentrative nucleoside transporter USA300HOU_RS13665 2.29 3.12E-03 MarR family transcriptional regulator USA300HOU_RS13095 hlgA 2.30 8.97E-04 Gamma-hemolysin component A USA300HOU_RS01655 2.35 2.51E-03...”

pRL80098 hypothetical protein from Rhizobium leguminosarum bv. viciae 3841
Aligns to 13:133 / 162 (74.7%), covers 98.3% of PF04343, 110.8 bits

• The Use of Transposon Insertion Sequencing to Interrogate the Core Functional Genome of the Legume Symbiont Rhizobium leguminosarum
  Perry, Frontiers in microbiology 2016
  • “...protein pRL70167 PGI 11 0.27 11 ES 11 0.27 19 ES 0.0.2 Conserved hypothetical protein pRL80098 PGI 11 0.18 9.5 ES 11 0.64 8.14 GD 0.0.2 Conserved hypothetical protein PLASMID/(VMM/TY)-GROWTH IMPAIRED HYPOTHETICAL PROTEINS pRL100010 PVGI 3 0.33 3 GD 3 1 11.67 NE 0.0.2 Conserved hypothetical...”

YeaO / b1792 DUF488 domain-containing protein YeaO from Escherichia coli K-12 substr. MG1655
yeaO / RF|NP_416306 uncharacterized protein yeaO from Escherichia coli K12 (see paper)
b1792 orf, hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 4:112 / 115 (94.8%), covers 99.2% of PF04343, 110.3 bits

• 18th Congress of the European Hematology Association, Stockholm, Sweden, June 13–16, 2013
  , Haematologica 2013

STM1277 putative cytoplasmic protein from Salmonella typhimurium LT2
SC1288 putative cytoplasmic protein from Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Aligns to 4:112 / 115 (94.8%), covers 99.2% of PF04343, 107.5 bits

• Comparison of Salmonella enterica serovar Typhimurium LT2 and non-LT2 salmonella genomic sequences, and genotyping of salmonellae by using PCR
  Kim, Applied and environmental microbiology 2006
  • “...154 65 STM2453 270 65 STM2624 284 65 STM1269 425 65 STM1277 289 65 STM0538 288 65 STM3532 233 65 7 STM4509 312 65 8 STM0305 155 65 STM1408 187 65 STM1859...”
• Genetic analysis and characterization of a Caulobacter crescentus mutant defective in membrane biogenesis
  Hodgson, Journal of bacteriology 1984
  • “...str-153 (pVS1) SC1287 hisBI37::Tn5 ts-104 str-153 (pVS1) SC1288 SC1293 trpK107::Tn5 ts-104 str-153 (pVS1) SC1294 cvsB108::TnS ts-104 str-153 (pVSI) SC1300...”
  • “...SC1417 SC149Od SC1321d SC1294 AE5479 SC1382 AE5567 SC1293 SC1288 SC1287 absence of biotin. Samples were withdrawn from each culture at the times indicated in...”

XC_2584 hypothetical protein from Xanthomonas campestris pv. campestris str. 8004
Aligns to 36:158 / 205 (60.0%), covers 99.2% of PF04343, 106.7 bits

• Identification of Xanthomonas fragariae, Xanthomonas axonopodis pv. phaseoli, and Xanthomonas fuscans subsp. fuscans with novel markers and using a dot blot platform coupled with automatic data analysis
  Albuquerque, Applied and environmental microbiology 2011
  • “...XAC4128 XC_0087 XC_0608 XC_0783 XC_1392 XC_1727 XC_2088 XC_2584 XC_2679 XC_2818 XC_3130 XC_4065 XC_4193 XOO_0116 XOO_3261 XOO_3566 XOO_3728 X. axonopodis pv....”

PA1065 hypothetical protein from Pseudomonas aeruginosa PAO1
Aligns to 28:136 / 157 (69.4%), covers 99.2% of PF04343, 104.8 bits

• First report of environmental bla _PAC-1-carrying Aeromonas enteropelogenes
  Zhong, Microbiology spectrum 2023
  • “...128, CZA 128 PA0427 P. aeruginosa SRR12669069 2015 Patient (wound) Singapore CT 128, CZA 128 PA1065 P. aeruginosa SRR12669041 2018 Patient (blood) Singapore CT 128, CZA 128 PA1074 P. aeruginosa SRR12669038 2018 Patient (blood) Singapore NR PA174313 P. aeruginosa MK534438.1 2017 Patient rectal France (patient from...”
• Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PAO1: a global approach
  Nalca, Antimicrobial agents and chemotherapy 2006
  • “...83 73 71 76 74 75 79 80 77d 78d 72 PA0026 PA0888 PA1065 PA1342 Gene name Protein This study Nouwens et al. (29) Arevalo-Ferro et al. (1) 1 1 1 1 1 1 1 PA1493...”
• V-antigen genotype and phenotype analyses of clinical isolates of Pseudomonas aeruginosa
  Allmond, Journal of clinical microbiology 2004
  • “...PA1100 PA1019 PA1024 PA1034 PA1052 PA1060 PA1063 PA1064 PA1065 PA1067 PA1069 PA1070 PA1079 PA1080 PcrV phenotype for: Type of infection Source of isolate...”
  • “...region of the pcrGVHpopBD operons in the isolates PA1065 and PA1079, which were isolated from cystic fibrosis patients and showed suppression of PcrV secretion....”

WP_061869012 DUF488 domain-containing protein from Prevotella intermedia
Aligns to 8:119 / 122 (91.8%), covers 100.0% of PF04343, 103.1 bits

• Genomic and phenotypic comparison of Prevotella intermedia strains possessing different virulence in vivo
  Kwack, Virulence 2022
  • “...LytT 5.5683 WP_061869463 hybrid sensor histidine kinase/response regulator 3.3029 WP_061869215 AraC family transcriptional regulator 2.9004 WP_061869012 MarR family transcriptional regulator 2.0301 WP_014709474 AraC family transcriptional regulator - 17 WP_014709590 AraC family transcriptional regulator - 17 WP_044048113 TetR/AcrR family transcriptional regulator - 17 WP_061869376 Predicted transcriptional regulator,...”

Saci_2184 conserved Prokaryal protein from Sulfolobus acidocaldarius DSM 639
Aligns to 3:108 / 114 (93.0%), covers 100.0% of PF04343, 97.8 bits

• Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
  Lewis, mBio 2023
  • “...S. acidocaldarius cells identified genes associated with biofilm formation. Among the most biofilm-responsive genes was Saci_2184, expression of which increased 10.8-fold in the biofilm compared to planktonic culture, second only to the hypothetical protein gene Saci_0301 ( Fig.1 ). The high transcriptional response of Saci_0301 was...”
  • “...found to be regulated by a noncoding RNA, RrrR (RNase R-resistant RNA) ( 36 ). Saci_2184 and Saci_2183 encode a putative VapB type II antitoxin and its cognate VapC toxin, respectively. Using TAfinder ( 37 ), 17 type II toxin-antitoxin pairs are predicted in the S....”

SiRe_0629 DUF488 domain-containing protein from Sulfolobus islandicus REY15A
Aligns to 3:108 / 115 (92.2%), covers 100.0% of PF04343, 96.6 bits

• An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea
  Sun, Nucleic acids research 2018
  • “...regulated genes include six genes of 2- to 5-fold activation and three highly activated genes: SiRe_0629 and SiRe_0630 (910 folds), SiRe_0655 (47 folds), all of which are of unknown function. To this end, these data indicated that orc1-2 is no longer capable of mediating NQO-responsive expression....”

Rv3073c hypothetical protein from Mycobacterium tuberculosis H37Rv
Aligns to 8:115 / 118 (91.5%), covers 99.2% of PF04343, 94.7 bits

• Definition of the mycobacterial SOS box and use to identify LexA-regulated genes in Mycobacterium tuberculosis
  Davis, Journal of bacteriology 2002
  • “...to ORFc Induction ratio f Rv1378c Rv1379 (pyrR) Rv3073c Rv3074 Rv3370c (dnaE2) Rv3371 Rv3776 Rv0071 Rv0335c Rv0336 Rv0515 Rv1000c Rv1001 (arcA) Rv1702c Rv2100...”

CD630DERM_36140 DUF488 family protein from Clostridioides difficile
CD3614 hypothetical protein from Clostridium difficile 630
Aligns to 12:131 / 205 (58.5%), covers 95.9% of PF04343, 74.7 bits

• Redefining the Clostridioides difficile σ^B Regulon: σ^B Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide
  Boekhoud, mSphere 2020
  • “...chain CD630DERM_34760 atpZ 1.6 2.42E-04 Putative ATP synthase protein CD630DERM_36100 4.6 2.38E-05 Conserved hypothetical protein CD630DERM_36140 2.5 1.07E-05 Conserved hypothetical protein, DUF1130 family Other genes involved in oxidative/nitrosative stress positively regulated by B CD630DERM_01740 cooS 8.3 1.20E-06 Carbon monoxide dehydrogenase CD630DERM_12790 iscS2 2.8 2.00E-03 Cysteine desulfurase...”
• Redefining the Clostridioides difficile σ^B Regulon: σ^B Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide
  Boekhoud, mSphere 2020
  • “...B was demonstrated through in vitro runoff transcription of specific target genes ( cd0350 , cd3614 , cd3605 , and cd2963 ). Finally, we demonstrated that different antimicrobials and hydrogen peroxide induce these genes in a manner dependent on this sigma factor, using a plate-based luciferase...”
  • “...d -transpeptidase), cd3412 (encoding UvrB, involved in nucleotide excision repair), cd3605 (encoding a ferredoxin), and cd3614 (encoding a hypothetical protein involved in oxidative stress; Table2 ) were selected on the basis of differential expression in our transcriptome analyses ( Data Set S1 ) and those of...”
• Genome Location Dictates the Transcriptional Response to PolC Inhibition in Clostridium difficile
  van, Antimicrobial agents and chemotherapy 2019
  • “...on B for their expression under the conditions tested. CD3614 (encoding a hypothetical protein) shows a basal level of expression but no significant increase in...”
  • “...the predicted promoter areas of CD0350, CD2962, CD3614, and CD0007 were amplified with primers oIB-80/oIB-94, oIB-82/oIB-95, oIB-92/oIB-100, and oPH-19/oPH20,...”
• Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile
  Brouwer, PloS one 2011
  • “...and a putative transcriptional regulator, respectively (ORFs 3452 and 3476 in R20291 are homologues of CD3614 and CD3615 in strain 630). In 630, CTn 1 is integrated into CD0354, a gene encoding a hypothetical protein; an uninterrupted homologue of this gene is present in R20291. The...”

Saci_2166 hypothetical protein from Sulfolobus acidocaldarius DSM 639
Aligns to 3:108 / 116 (91.4%), covers 100.0% of PF04343, 73.1 bits

• Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
  Lewis, mBio 2023
  • “...19342851934725 146 + COG1733 VapC13 70607880 T Saci_2167 20007152001335 206 + VapC VapB13 70607879 A Saci_2166 20003532000703 116 + VapB VapC14 70607892 T Saci_2183 20193402019957 205 VapC VapB14 70607893 A Saci_2184 20199832020327 114 VapB VapC15 70607901 T Saci_2192 20322462032686 146 PIN-like VapB15 70607902 A Saci_2193 20326462032906...”
• The genome-scale DNA-binding profile of BarR, a β-alanine responsive transcription factor in the archaeon Sulfolobus acidocaldarius
  Liu, BMC genomics 2016
  • “...+* + +* 1964490 both 4.3/6.6 Saci_2137 Aminotransferase inter-5 +* + +* 2000304 w/o N.A./3.7 Saci_2166 Uroporphyrin-III methyltransferase intra-5 N.A. + N.A. 2166455 both 2.2/7.2 Saci_2319 Hypothetical protein inter ++ + +** a Growth condition in which the binding region was detected above the significance level:...”

Synpcc7942_0758 hypothetical protein from Synechococcus elongatus PCC 7942
Aligns to 22:128 / 140 (76.4%), covers 96.7% of PF04343, 61.1 bits

• Blueprint for a minimal photoautotrophic cell: conserved and variable genes in Synechococcus elongatus PCC 7942
  Delaye, BMC genomics 2011
  • “...method, these are two genes coding for PilA-like proteins (Synpcc7942_0048, Synpcc7942_0049), two hypothetical proteins (Synpcc7942_0757, Synpcc7942_0758), and two XRE family transcriptional regulators (Synpcc7942_0763, Synpcc7942_0764). Operon structure of xenologous genes We looked at the predicted operon structure of those genes classified as xenologs to see if other...”

D1832_RS13660, WP_118914870 DUF488 domain-containing protein from Dermacoccus abyssi
Aligns to 13:147 / 163 (82.8%), covers 97.5% of PF04343, 54.8 bits

• Whole Genome Sequence of Dermacoccus abyssi MT1.1 Isolated from the Challenger Deep of the Mariana Trench Reveals Phenazine Biosynthesis Locus and Environmental Adaptation Factors
  Abdel-Mageed, Marine drugs 2020
  • “...Enamine/imine deaminase activity RidA family protein [ Streptomyces exfoliatus ] WP_037644077 80.30% 99% 2e-71 12 D1832_RS13660 492 DUF488 domain-containing protein WP_118914870 Unknown DUF488 domain-containing protein [ Streptosporangiaceae bacterium YIM 75507] WP_119930667 68.12% 98% 5e-70 13 D1832_RS13665 393 DUF4186 domain-containing protein WP_118914823 Unknown DUF4186 domain-containing protein [...”
  • “...protein [ Streptomyces exfoliatus ] WP_037644077 80.30% 99% 2e-71 12 D1832_RS13660 492 DUF488 domain-containing protein WP_118914870 Unknown DUF488 domain-containing protein [ Streptosporangiaceae bacterium YIM 75507] WP_119930667 68.12% 98% 5e-70 13 D1832_RS13665 393 DUF4186 domain-containing protein WP_118914823 Unknown DUF4186 domain-containing protein [ Nocardia suismassiliense ] WP_107655452 81.15%...”

Or search for genetic data about PF04343 in the Fitness Browser