Family Search for PF04356 (DUF489)

PF04356 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

HslZ / b1132 lysogenization regulator from Escherichia coli K-12 substr. MG1655 (see 4 papers)
HFLD_ECOLI / P25746 High frequency lysogenization protein HflD from Escherichia coli (strain K12) (see paper)
b1132 hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 7:200 / 213 (91.1%), covers 99.5% of PF04356, 250.9 bits

• function: Negative regulator of phage lambda lysogenization. Contributes to the degradation of the phage regulatory protein CII. Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
  subunit: Interacts with CII protein from phage lambda.
  disruption phenotype: Cells lacking this gene show an increased lysogenization frequency.
• The gut microbiota correlate with the disease characteristics and immune status of patients with untreated diffuse large B-cell lymphoma
  Lin, Frontiers in immunology 2023
  • “...functions, so 75 proteins were specific to c_Gammaproteobacteria or o_Enterobacteriales , while four including b0354, b1132, b1179, and b3033 were present only in c_Gammaproteobacteria. The functions of these specific proteins may help explain the common physiological or biochemical characteristics of these bacteria and future studies may...”
• Genome-wide expression profiling in Escherichia coli K-12
  Richmond, Nucleic acids research 1999
  • “...V production b1903 b1903 -6.2 -1.0 ORF, hypothetical protein b1132 ycfC -6.5 -1.2 ORF, hypothetical protein b1076 flgE -6.6 -22.7 b0523 purE -6.6 1.9 b2508 guaB...”

c1511 Hypothetical protein ycfC from Escherichia coli CFT073
Aligns to 9:202 / 215 (90.2%), covers 99.5% of PF04356, 250.2 bits

• The γ-Core Motif Peptides of Plant AMPs as Novel Antimicrobials for Medicine and Agriculture
  Slezina, International journal of molecular sciences 2022
  • “...around 4 mm, and no activity against C. gloeosporioides DoA d0762 and C. capsici DoA c1511 at 1.024 mg/mL; it inhibited the growth of methicillin resistant Staphylococcus aureus (MRSA, ATCC 43300) with MIC 99 = 2.23 mg/mL and the growth of Salmonella Typhi (ATCC 13311) with...”
  • “...a concentration of 0.512 mg/mL and against C. gloeosporioides DoA d0762 and C. capsici DoA c1511 at 1.024 mg/mL. [ 25 ] BhDef12M GV C G RRR A C +3 BhDef12M showed inhibitory activity against C. gloeosporioides DoA c1060 at a concentration of 0.52 mM (0.512mg/mL)...”
• The secondary metabolites of rare actinomycetes: chemistry and bioactivity
  Ding, RSC advances 2019
  • “...antifungal activity against Colletotrichum gloeosporioides DoA d0762, Colletotrichum gloeosporioides DoA c1060 and Colletotrichum capsici DoA c1511, which could lead to anthracnose disease. Additionally, the pathogenic yeasts Candida albicans MT 2013/1, Candida parasilopsis DKMU 434 and Cryptococcus neoformans MT 2013/2 also were inhibited by the compounds (MIC...”
• Identification of in vivo-induced antigens including an RTX family exoprotein required for uropathogenic Escherichia coli virulence
  Vigil, Infection and immunity 2011
  • “...c3293-c3291 c0446 c5470 c0498 c5419 c2381 c4480 c1511 Function of gene product Respiratory nitrate reductase 1 Probable cytochrome c peroxidase Polynucleotide...”

ECs1604 hypothetical protein from Escherichia coli O157:H7 str. Sakai
Aligns to 7:200 / 213 (91.1%), covers 99.5% of PF04356, 249.1 bits

• Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium
  Bergholz, BMC microbiology 2007
  • “...ptsG -3.09 1 ECs0124 speD -2.74 1 ECs1492 mfd -2.33 1 ECs0149 dksA 2.12 2 ECs1604 ycfC -2.19 1 ECs0150 sfsA 2.83 2 ECs1662 O157 -2.53 1 ECs0191 yaeO 2.42 2 ECs1684 dadA 2.34 2 ECs0207 dniR -2.11 1 ECs1710 ychH 4.61 2 ECs0334 O157 -2.07...”

PA2627 hypothetical protein from Pseudomonas aeruginosa PAO1
Q9I0L1 High frequency lysogenization protein HflD homolog from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Aligns to 6:198 / 206 (93.7%), covers 99.5% of PF04356, 239.8 bits

• Characterization of temporal protein production in Pseudomonas aeruginosa biofilms
  Southey-Pillig, Journal of bacteriology 2005
  • “...............................................................................................................................................................................PA2627 Sigma...”
  • “...protein PA2677 and a conserved hypothetical protein PA2627), pattern B (probable chemotaxis transducer PA4844), pattern D (heat shock protein PA1596), and...”
• Over-Expression of Hypochlorite Inducible Major Facilitator Superfamily (MFS) Pumps Reduces Antimicrobial Drug Susceptibility by Increasing the Production of MexXY Mediated by ArmZ in Pseudomonas aeruginosa
  Dulyayangkul, Frontiers in microbiology 2020
  • “...UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase WbpE <0.05 0.010 0.16 0.019 Q9HZG8 Uncharacterized protein PA3040 <0.05 0.006 0.12 0.014 Q9I0L1 High frequency lysogenization protein HflD homolog HflD 10.30 0.001 5.39 0.008 Q9I0L5 Isocitrate dehydrogenase [NADP] Icd <0.05 0.000 0.16 0.007 Q9I2W9 Phosphoenolpyruvate synthase PpsA <0.05 0.002 <0.05 0.002 Q9I314 Type...”

HI0638 conserved hypothetical protein from Haemophilus influenzae Rd KW20
P44796 High frequency lysogenization protein HflD homolog from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Aligns to 6:195 / 205 (92.7%), covers 99.5% of PF04356, 231.3 bits

• The availability of purine nucleotides regulates natural competence by controlling translation of the competence activator Sxy
  Sinha, Molecular microbiology 2013
  • “...TGGCAAACGATTGCTA HI0495 85 aphA phosphatase, periplasmic 4.88 AAGTAAACGATTGTGT HI0464 34 rpiA-serA purine biosynthesis 4.84 AGGAAAACGTTTCCGT HI0638 26 hflD-purB purine biosynthesis 4.59 ATGCAAACGATTACTC HI0667 76 glpX phosphatase,cytoplasmic 4.54 ATAAAATCGTTTGCTA HI1153 41 hpt purine biosynthesis The PurR-binding motif of Ravcheev et al . ( 2002 ) was used...”
• Functional annotation of conserved hypothetical proteins from Haemophilus influenzae Rd KW20
  Shahbaaz, PloS one 2013
  • “...2, -like domain family 98. HP HI0633 950781 P44026 Voltage gated chloride channel 99. HP HI0638 950538 P44796 High frequency lysogenization protein HflD 100. HP HI0650 949696 P44028 Prokaryotic membrane lipoprotein lipid attachment site profile protein 101. HP HI0656 950161 P44807 tRNAthreonylcarbamoyladenosine biosynthesis protein RimN 102....”
• Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae
  Gladitz, Nucleic acids research 2005
  • “...region HI0554 (homol. to transposase) HI0554 30 181 39.08 UU 4.5 72.21 Conserved hypothetical protein HI0638 38 205 37.07 HP2 0 65.62 Conserved hypothetical protein (homol. to DNA topoisomerase) HI0656.1 39 179 39.7 AA 0.4 74.86 Conserved hypothetical protein (4-diphosphocytidyl-2- C -methylerythritol synthase-like protein) HI0672 40...”
• Cloning of genes of nontypeable Haemophilus influenzae involved in penetration between human lung epithelial cells
  van, Infection and immunity 2000
  • “...cell line NCI-H292 were identified. ORFs HI0636 and HI0638, encoding two small proteins of unknown functions, were further investigated. The clone containing...”
  • “...and HI0637 as well as the clone containing ORF HI0638 showed a significant increase in penetration. Disruption of HI0638 by kanamycin box insertion in H....”
• Functional annotation of conserved hypothetical proteins from Haemophilus influenzae Rd KW20
  Shahbaaz, PloS one 2013
  • “...domain family 98. HP HI0633 950781 P44026 Voltage gated chloride channel 99. HP HI0638 950538 P44796 High frequency lysogenization protein HflD 100. HP HI0650 949696 P44028 Prokaryotic membrane lipoprotein lipid attachment site profile protein 101. HP HI0656 950161 P44807 tRNAthreonylcarbamoyladenosine biosynthesis protein RimN 102. HP HI0656.1...”

ACIAD1220 conserved hypothetical protein; putative protein involved in purine metabolism from Acinetobacter sp. ADP1
Aligns to 17:230 / 243 (88.1%), covers 99.5% of PF04356, 163.9 bits

• Characterization of Highly Ferulate-Tolerant Acinetobacter baylyi ADP1 Isolates by a Rapid Reverse Engineering Method
  Luo, Applied and environmental microbiology 2022 (secret)
• Ranking essential bacterial processes by speed of mutant death
  Gallagher, Proceedings of the National Academy of Sciences of the United States of America 2020 (secret)

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