Family Search for PF04356 (DUF489)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF04356 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

HslZ / b1132 lysogenization regulator from Escherichia coli K-12 substr. MG1655 (see 4 papers)
HFLD_ECOLI / P25746 High frequency lysogenization protein HflD from Escherichia coli (strain K12) (see paper)
Aligns to 7:200 / 213 (91.1%), covers 99.5% of PF04356, 250.9 bits

• function: Negative regulator of phage lambda lysogenization. Contributes to the degradation of the phage regulatory protein CII. Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
  subunit: Interacts with CII protein from phage lambda.
  disruption phenotype: Cells lacking this gene show an increased lysogenization frequency.

Or search for genetic data about PF04356 in the Fitness Browser