Family Search for PF04430 (DUF498)
PF04430.14 hits 19 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
BCAL1928 hypothetical protein (RefSeq) from Burkholderia cenocepacia J2315
Aligns to 14:121 / 124 (87.1%), covers 100.0% of PF04430, 116.3 bits
- Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS
Wong, Frontiers in microbiology 2016 - “...Ortega et al., 2007 ). Conditional lethal mutants of arnT and arnB but not the BCAL1928 mutant, exhibited severe growth defects when grown under a non-permissive condition ( Ortega et al., 2007 ). Our TraDIS data supports the essentiality of these genes, as transposon insertions are...”
- A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability
Mohamed, Glycobiology 2014 - “...with 0.2% rhamnose or 0.2% glucose. XOA10 (Prha:: BCAL1928) and XOA11 (Prha::arnT) are rhamnose-independent and -dependent control mutants (Ortega et al. 2007)....”
- “...ceftazidime and imipenem as the XOA10 (Prha:: BCAL1928) control strain (Table II). However, the Prha:: murJBc bacteria grown under rhamnose-limiting conditions...”
- A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability
Ortega, Journal of bacteriology 2007 - “...each target gene consistently failed. In contrast, the genes BCAL1928 and BCAL1936 that flank each end of the putative arn cluster were readily mutated. We...”
- “...mutant in which this plasmid interrupts the gene locus BCAL1928 (strain XOA10) and which served as a negative control (Fig. 1A). Also, as a positive control for...”
NDUF3_MOUSE / Q9JKL4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Protein 2P1 from Mus musculus (Mouse) (see paper)
NP_075736 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Mus musculus
Aligns to 61:169 / 185 (58.9%), covers 100.0% of PF04430, 114.1 bits
TR70_0856 Xcc1710-like domain-containing protein from Burkholderia pseudomallei
Aligns to 26:133 / 136 (79.4%), covers 100.0% of PF04430, 113.6 bits
- Combating biothreat pathogens: ongoing efforts for countermeasure development and unique challenges
Duplantier, Drug Discovery Targeting Drug-Resistant Bacteria 2020 - “...l -methionine-dependent methyltransferase, amrR [186] , [187] Lactams penA a , nlpD1, dacC, FlgN, sch, TR70_0856, TR70_1911, ftsI, amrR , bpeR , bpeT , spoT , tRNA, rRNA, proteins with unknown function, SerS seryl-tRNA synthetase, and RND efflux pump AmrAB-OprA, and BpeEF-OprC [186] , [188] ,...”
NDUF3_RAT / O08776 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Nuclear protein E3-3 from Rattus norvegicus (Rat) (see paper)
Aligns to 61:169 / 185 (58.9%), covers 100.0% of PF04430, 113.1 bits
- function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
subunit: Interacts with NDUFAF4, NDUFS2 and NDUFS3.
NP_951056 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform b from Homo sapiens
Aligns to 3:111 / 127 (85.8%), covers 100.0% of PF04430, 112.8 bits
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson, PloS one 2010 - GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
- Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.
Saada, American journal of human genetics 2009 - GeneRIF: Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.
- 2P1, a novel male mouse cDNA specifically expressed during meiosis.
Hammami-Hamza, The International journal of developmental biology 2003 (PubMed)- GeneRIF: Describes a similar transcript in mouse.
- Molecular cloning of a novel alternatively spliced nuclear protein.
Hartmann, Biochimica et biophysica acta 1997 (PubMed)- GeneRIF: Describes a similar transcript in rat, and compares it to human and mouse transcripts.
NDUF3_HUMAN / Q9BU61 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Homo sapiens (Human) (see 2 papers)
Aligns to 60:168 / 184 (59.2%), covers 100.0% of PF04430, 111.4 bits
- function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
subunit: Interacts with NDUFAF4, NDUFS2 and NDUFS3. - Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases.
Giachin, Frontiers in molecular biosciences 2016 - “...Calvo et al., 2010 ; Herzer et al., 2010 ; Ghaloul-Gonzalez et al., 2016 NDUFAF3 Q9BU61 M1T, G77R, R122P FLA Saada et al., 2009 NDUFAF4 Q9P032 L65P LS, L Saada et al., 2009 NDUFAF5 Q5TEU4 L159F, L229P LS Sugiana et al., 2008 ; Gerards et al.,...”
Q7VV99 Uncharacterized protein from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Aligns to 14:145 / 150 (88.0%), covers 100.0% of PF04430, 108.0 bits
AT3G60150 hypothetical protein (RefSeq) from Arabidopsis thaliana
Aligns to 56:164 / 170 (64.1%), covers 98.2% of PF04430, 105.6 bits
RL2056 hypothetical protein (NCBI) from Rhizobium leguminosarum bv. viciae 3841
Aligns to 18:126 / 128 (85.2%), covers 100.0% of PF04430, 101.6 bits
RPA2829 conserved hypothetical protein (NCBI) from Rhodopseudomonas palustris CGA009
Aligns to 16:124 / 127 (85.8%), covers 100.0% of PF04430, 95.9 bits
NP_001023328 NADH:Ubiquinone oxidoreductase Assembly Factor from Caenorhabditis elegans
Aligns to 72:183 / 270 (41.5%), covers 96.3% of PF04430, 90.7 bits
ECH_0516 hypothetical protein (NCBI) from Ehrlichia chaffeensis str. Arkansas
Aligns to 14:118 / 120 (87.5%), covers 100.0% of PF04430, 87.4 bits
XC_2521 hypothetical protein (NCBI) from Xanthomonas campestris pv. campestris str. 8004
Aligns to 15:121 / 124 (86.3%), covers 94.5% of PF04430, 84.8 bits
NGO_0780 Mth938-like domain-containing protein from Neisseria gonorrhoeae FA 1090
Aligns to 15:122 / 123 (87.8%), covers 97.2% of PF04430, 79.4 bits
- Discovery of a New Neisseria gonorrhoeae Type IV Pilus Assembly Factor, TfpC
Hu, mBio 2020 - “...surrounding genes in the operon as determined by quantitative RT-PCR Locus Fold change NGO_0779 1.1 NGO_0780 2.4 NGO_0781 2 NGO_0782 2.7 NGO_0784 2.2 NGO_0785 2.4 FIG2 Analysis of pilus-dependent colony morphology. (A) Stereo-micrograph pictures of 22-h N. gonorrhoeae colonies grown with or without 0.1mM IPTG in...”
FTN_0426 hypothetical protein (NCBI) from Francisella tularensis subsp. novicida U112
FTT_0900 hypothetical protein (RefSeq) from Francisella tularensis subsp. tularensis SCHU S4
Aligns to 15:123 / 123 (88.6%), covers 99.1% of PF04430, 79.2 bits
Q9JZ97 Uncharacterized protein from Neisseria meningitidis serogroup B (strain MC58)
Aligns to 23:130 / 131 (82.4%), covers 97.2% of PF04430, 78.5 bits
AAMDC_MOUSE / Q8R0P4 Mth938 domain-containing protein; LI2 from Mus musculus (Mouse) (see 2 papers)
Aligns to 6:119 / 122 (93.4%), covers 100.0% of PF04430, 75.1 bits
- function: May play a role in preadipocyte differentiation and adipogenesis.
Q9H7C9 Mth938 domain-containing protein from Homo sapiens
Aligns to 6:119 / 122 (93.4%), covers 100.0% of PF04430, 74.4 bits
PAB1927 hypothetical protein (NCBI ptt file) from Pyrococcus abyssi GE5
Aligns to 3:115 / 118 (95.8%), covers 92.7% of PF04430, 36.9 bits
- Phylogenomic analysis of proteins that are distinctive of Archaea and its main subgroups and the origin of methanogenesis
Gao, BMC genomics 2007 - “...methanogenic archaea, Archaeoglobus and Thermococci. The first 5 proteins in Table 7(a) (PAB0076, PAB0138, PAB0965, PAB1927 and PAB1994) are present in all of the Thermococci and most of the methanogens. Four of these proteins are also present in A. fulgidus . The next 13 proteins in...”
- “...CDD15620 PAB1291 [NP_127284] CDD41906 PAB0138 [NP_125896] CDD9576 PAB1584 [NP_126876] COG4072 PAB0965 [NP_127127] CDD15705 PAB1860 [NP_126440] PAB1927 1 [NP_126347] CDD29323 PAB0813 [NP_126902] COG1630 PAB1994 [NP_126245] CDD9568 PAB0853 [NP_126970] PAB0036 [NP_125764] PAB1251 [NP_127332] endonuclease COG3780 PAB0054 [NP_125787] CDD41919 PAB1779 [NP_126559] CDD43950 PAB0176 [NP_125948] CDD43579 PAB1806 2 [NP_126515] CDD43599...”
Or search for genetic data about PF04430 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory