Family Search for PF04430 (DUF498)
Running HMMer for PF04430
PF04430 hits 25 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
BCAL1928 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 14:121 / 124 (87.1%), covers 100.0% of PF04430, 123.9 bits
- Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS
Wong, Frontiers in microbiology 2016 - “...Ortega et al., 2007 ). Conditional lethal mutants of arnT and arnB but not the BCAL1928 mutant, exhibited severe growth defects when grown under a non-permissive condition ( Ortega et al., 2007 ). Our TraDIS data supports the essentiality of these genes, as transposon insertions are...”
- A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability
Mohamed, Glycobiology 2014 - “...with 0.2% rhamnose or 0.2% glucose. XOA10 (Prha:: BCAL1928) and XOA11 (Prha::arnT) are rhamnose-independent and -dependent control mutants (Ortega et al. 2007)....”
- “...ceftazidime and imipenem as the XOA10 (Prha:: BCAL1928) control strain (Table II). However, the Prha:: murJBc bacteria grown under rhamnose-limiting conditions...”
- A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability
Ortega, Journal of bacteriology 2007 - “...each target gene consistently failed. In contrast, the genes BCAL1928 and BCAL1936 that flank each end of the putative arn cluster were readily mutated. We...”
- “...mutant in which this plasmid interrupts the gene locus BCAL1928 (strain XOA10) and which served as a negative control (Fig. 1A). Also, as a positive control for...”
NDUF3_MOUSE / Q9JKL4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Protein 2P1 from Mus musculus (Mouse) (see paper)
NP_075736 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Mus musculus
Aligns to 61:169 / 185 (58.9%), covers 100.0% of PF04430, 122.7 bits
NDUF3_RAT / O08776 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Nuclear protein E3-3 from Rattus norvegicus (Rat) (see paper)
Aligns to 61:169 / 185 (58.9%), covers 100.0% of PF04430, 121.9 bits
- function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
subunit: Interacts with NDUFAF4, NDUFS2 and NDUFS3.
TR70_0856 Mth938-like domain-containing protein from Burkholderia pseudomallei
Aligns to 14:121 / 124 (87.1%), covers 100.0% of PF04430, 120.9 bits
- Combating biothreat pathogens: ongoing efforts for countermeasure development and unique challenges
Duplantier, Drug Discovery Targeting Drug-Resistant Bacteria 2020 - “...l -methionine-dependent methyltransferase, amrR [186] , [187] Lactams penA a , nlpD1, dacC, FlgN, sch, TR70_0856, TR70_1911, ftsI, amrR , bpeR , bpeT , spoT , tRNA, rRNA, proteins with unknown function, SerS seryl-tRNA synthetase, and RND efflux pump AmrAB-OprA, and BpeEF-OprC [186] , [188] ,...”
NP_951056 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform b from Homo sapiens
Aligns to 3:111 / 127 (85.8%), covers 100.0% of PF04430, 120.7 bits
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson, PloS one 2010 - GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
- Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.
Saada, American journal of human genetics 2009 - GeneRIF: Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.
- 2P1, a novel male mouse cDNA specifically expressed during meiosis.
Hammami-Hamza, The International journal of developmental biology 2003 (PubMed)- GeneRIF: Describes a similar transcript in mouse.
- Molecular cloning of a novel alternatively spliced nuclear protein.
Hartmann, Biochimica et biophysica acta 1997 (PubMed)- GeneRIF: Describes a similar transcript in rat, and compares it to human and mouse transcripts.
BTH_I2196 Protein of unknown function, DUF598 family from Burkholderia thailandensis E264
Aligns to 63:170 / 173 (62.4%), covers 100.0% of PF04430, 120.0 bits
- A Burkholderia thailandensis DedA Family Membrane Protein Is Required for Proton Motive Force Dependent Lipid A Modification
Panta, Frontiers in microbiology 2020 - “...Figure S1 ). Primers FWAra4NT and REVAra4NT were used to amplify 330 bp portion of BTH_I2196, the first gene in arn transport cluster ( Supplementary Figure S1 ). The PCR fragments were ligated to pSC200 using Nde1 and Xba1 restriction sites, upstream of the rhamnose promoter,...”
- “...with ArnA), BTH_I2189 (36% identity with ArnD). Another transcriptional unit encodes arn transport gene products- BTH_I2196, BTH_I2195 (23% identity with ArnT), and BTH_I2194 (27% identity with ArnE/ArnF) ( Figure 1A ). Alignments were performed using Needleman-Wunsch alignment ( Altschul et al., 1997 , 2005 ). In...”
NDUF3_HUMAN / Q9BU61 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Homo sapiens (Human) (see 2 papers)
Aligns to 60:168 / 184 (59.2%), covers 100.0% of PF04430, 119.8 bits
RL2056 hypothetical protein from Rhizobium leguminosarum bv. viciae 3841
Aligns to 18:126 / 128 (85.2%), covers 100.0% of PF04430, 107.8 bits
AT3G60150 hypothetical protein from Arabidopsis thaliana
Aligns to 56:164 / 170 (64.1%), covers 99.1% of PF04430, 106.1 bits
CG5569 uncharacterized protein from Drosophila melanogaster
Aligns to 59:170 / 196 (57.1%), covers 100.0% of PF04430, 105.1 bits
- Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis
Murari, iScience 2021 - “...search on the Ensembl genome browser revealed that Drosophila orthologs of NDUFAF3 and NDUFAF4 are CG5569 and CG11722, respectively. For simplicity, we refer to CG5569 and CG11722 as dNDUFAF3 and dNDUFAF4, respectively, and prefix all Drosophila orthologs of CI subunits and CIAFs with d (asin dNDUFAF3...”
- “...anti-dNDUFA8 (CG3683) This paper N/A Rabbit polyclonal anti-dNDUFAF1 (CG7598) This paper N/A Rabbit polyclonal anti-dNDUFAF3 (CG5569) This paper N/A Rabbit polyclonal anti-dNDUFAF4 (CG11722) This paper N/A Rabbit polyclonal anti-dTIMMDC1 (CG9852) This paper N/A Rabbit polyclonal anti-dECSIT (CG10610) This paper N/A Rabbit polyclonal anti-dNDUFS5 (CG11752) Murari etal.,...”
SALWKB2_RS05210 Mth938-like domain-containing protein from Snodgrassella alvi wkB2
Aligns to 14:120 / 125 (85.6%), covers 99.1% of PF04430, 102.4 bits
RPA2829 conserved hypothetical protein from Rhodopseudomonas palustris CGA009
Aligns to 16:124 / 127 (85.8%), covers 100.0% of PF04430, 99.9 bits
Q7VV99 Xcc1710-like domain-containing protein from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Aligns to 14:145 / 150 (88.0%), covers 100.0% of PF04430, 98.1 bits
Q54CZ9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Dictyostelium discoideum
DDB_G0292722 hypothetical protein from Dictyostelium discoideum AX4
Aligns to 12:121 / 284 (38.7%), covers 100.0% of PF04430, 97.3 bits
- Dictyostelium discoideum as a non-mammalian biomedical model
Martín-González, Microbial biotechnology 2021 - “...Q55BR7 DDB_G0279405 Q54WW7 rasD, gefE, NS gefL P03967, Q8IS18, B0M0P8 DDB_G0291852 Q54E48 rblA Q54FX2 DDB_G0292722 Q54CZ9 regA Q23917 hspA Q54J97 ripA C7G030 lkb1 Q54WJ0 rps4 P51405 lst8 Q54D08 snfA Q54YF2 midA Q54S83 tor Q86C65 ndufaf5 Q54JW0 trap1 Q86L04 ndufs4 Q8T1V6 GcvH1 Q54JV8 ndufs7 Q54NI6 DDB_G0281081 Q54UH1...”
- Dictyostelium discoideum as a non-mammalian biomedical model
Martín-González, Microbial biotechnology 2021 - “...raptor Q55BR7 DDB_G0279405 Q54WW7 rasD, gefE, NS gefL P03967, Q8IS18, B0M0P8 DDB_G0291852 Q54E48 rblA Q54FX2 DDB_G0292722 Q54CZ9 regA Q23917 hspA Q54J97 ripA C7G030 lkb1 Q54WJ0 rps4 P51405 lst8 Q54D08 snfA Q54YF2 midA Q54S83 tor Q86C65 ndufaf5 Q54JW0 trap1 Q86L04 ndufs4 Q8T1V6 GcvH1 Q54JV8 ndufs7 Q54NI6 DDB_G0281081...”
NP_001023328 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 from Caenorhabditis elegans
Aligns to 72:183 / 270 (41.5%), covers 97.2% of PF04430, 95.4 bits
XC_2521 hypothetical protein from Xanthomonas campestris pv. campestris str. 8004
Aligns to 14:121 / 124 (87.1%), covers 96.3% of PF04430, 95.3 bits
ECH_0516 hypothetical protein from Ehrlichia chaffeensis str. Arkansas
Aligns to 14:118 / 120 (87.5%), covers 100.0% of PF04430, 93.2 bits
NGO_0780 Mth938-like domain-containing protein from Neisseria gonorrhoeae FA 1090
Aligns to 15:122 / 123 (87.8%), covers 97.2% of PF04430, 86.9 bits
- Discovery of a New Neisseria gonorrhoeae Type IV Pilus Assembly Factor, TfpC
Hu, mBio 2020 - “...surrounding genes in the operon as determined by quantitative RT-PCR Locus Fold change NGO_0779 1.1 NGO_0780 2.4 NGO_0781 2 NGO_0782 2.7 NGO_0784 2.2 NGO_0785 2.4 FIG2 Analysis of pilus-dependent colony morphology. (A) Stereo-micrograph pictures of 22-h N. gonorrhoeae colonies grown with or without 0.1mM IPTG in...”
Q9JZ97 Rod shape-determining protein RodA from Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Aligns to 23:130 / 131 (82.4%), covers 97.2% of PF04430, 85.8 bits
FTN_0426 hypothetical protein from Francisella tularensis subsp. novicida U112
FTT_0900 hypothetical protein from Francisella tularensis subsp. tularensis SCHU S4
Aligns to 15:123 / 123 (88.6%), covers 99.1% of PF04430, 81.5 bits
A0A4X1U924 Adipogenesis associated Mth938 domain containing from Sus scrofa
Aligns to 13:126 / 129 (88.4%), covers 100.0% of PF04430, 80.3 bits
AAMDC_MOUSE / Q8R0P4 Mth938 domain-containing protein; LI2 from Mus musculus (Mouse) (see 2 papers)
Aligns to 6:119 / 122 (93.4%), covers 100.0% of PF04430, 79.4 bits
- function: May play a role in preadipocyte differentiation and adipogenesis.
Q9H7C9 Mth938 domain-containing protein from Homo sapiens
Aligns to 6:119 / 122 (93.4%), covers 100.0% of PF04430, 78.3 bits
- Use of iTRAQ-based quantitative proteomic identification of CHGA and UCHL1 correlated with lymph node metastasis in colorectal carcinoma.
Lee, Journal of cellular and molecular medicine 2023 - “...P01833 PIGR Polymeric immunoglobulin receptor 0.605 21 P62280 RPS11 40S ribosomal protein S11 0.569 22 Q9H7C9 AAMDC Mth938 domaincontaining protein 0.610 23 P62854 RPS26 40S ribosomal protein S26 0.535 24 P62829 RPL23 60S ribosomal protein L23 0.543 25 P46776 RPL27A 60S ribosomal protein L27a 0.599 26...”
- Proteomics identifies differentially expressed proteins in glioblastoma U87 cells treated with hederagenin.
Zhang, Proteome science 2023 - “...cdc2-inhibitory kinase DOWN 0.754385965 0.0433306 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 DOWN 0.754385965 0.02863485 Q9H7C9 AAMDC Mth938 domain-containing protein DOWN 0.738122827 0.02926776 P02533 KRT14 Keratin, type I cytoskeletal 14 DOWN 0.71743487 0.04167076 P01024 C3 Complement C3 DOWN 0.713796058 0.04877362 Q8NFP7 NUDT10 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha...”
- Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients
Skeffington, Journal of clinical medicine 2019 - “...0.032 0.82 1.49 F2Z2V0 CPNE1 Copine-1 (Fragment) 0.86 1.45 0.11 0.25 0.59 0.038 0.75 1.42 Q9H7C9 AAMDC Mth938 domain-containing protein 1.39 2.31 0.25 0.16 0.60 0.020 0.73 1.71 O95865 DDAH2 N(G), N(G)-dimethylarginine dimethylaminohydrolase 2 1.57 2.60 0.32 0.29 0.61 0.047 0.72 1.33 Q5T6V5 C9orf64 UPF0553 protein...”
- Identification of Candidate Protein Markers in Skeletal Muscle of Laminin-211-Deficient CMD Type 1A-Patients
Kölbel, Frontiers in neurology 2019 - “...misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome Q9H7C9 4/4 0.02 Mth938 domain-containing protein ( AAMDC ) Cytoplasm 0.36 1.47 Plays a role in preadipocyte differentiation and adipogenesis Q8N8N7 5/5 0.02 Prostaglandin reductase 2 ( PTGR2 ) Cytoplasm 0.29...”
- The human olfactory cleft mucus proteome and its age-related changes.
Yoshikawa, Scientific reports 2018 - “...Q9NR19 79613 Acetyl-coenzyme A synthetase, cytoplasmic 0.41 0.0443 0.0 0.0 0.1 0.0 0.0 0.0 46 Q9H7C9 13438 UPF0366 protein C11orf67 0.41 0.0443 0.0 0.0 0.5 0.1 0.3 0.0 47 P41218 46092 Myeloid cell nuclear differentiation antigen 0.41 0.0453 0.9 0.1 1.7 0.1 1.3 0.1 48 P53609...”
- In-Depth, Label-Free Analysis of the Erythrocyte Cytoplasmic Proteome in Diamond Blackfan Anemia Identifies a Unique Inflammatory Signature.
Pesciotta, PloS one 2015 - “...protein 2 OSBP2 12 3E-05 -3.7 Q8TDZ6 Glia maturation factor gamma GMFG 2 4E-05 -28436 Q9H7C9 Mth938 domain-containing protein AAMDC 2 0.0006 -4913.5 O43488 Aflatoxin B1 aldehyde reductase member 2 AKR7A2 2 0.0056 -1321.7 Ingenuity Pathway Analysis (IPA) software was used to investigate common pathways and...”
- Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2.
Tanaka, Monoclonal antibodies in immunodiagnosis and immunotherapy 2014
E9PR47 Adipogenesis associated Mth938 domain containing from Homo sapiens
Aligns to 6:165 / 168 (95.2%), covers 100.0% of PF04430, 72.3 bits
PAB1927 hypothetical protein from Pyrococcus abyssi GE5
Aligns to 3:115 / 118 (95.8%), covers 97.2% of PF04430, 42.1 bits
- Phylogenomic analysis of proteins that are distinctive of Archaea and its main subgroups and the origin of methanogenesis
Gao, BMC genomics 2007 - “...methanogenic archaea, Archaeoglobus and Thermococci. The first 5 proteins in Table 7(a) (PAB0076, PAB0138, PAB0965, PAB1927 and PAB1994) are present in all of the Thermococci and most of the methanogens. Four of these proteins are also present in A. fulgidus . The next 13 proteins in...”
- “...CDD15620 PAB1291 [NP_127284] CDD41906 PAB0138 [NP_125896] CDD9576 PAB1584 [NP_126876] COG4072 PAB0965 [NP_127127] CDD15705 PAB1860 [NP_126440] PAB1927 1 [NP_126347] CDD29323 PAB0813 [NP_126902] COG1630 PAB1994 [NP_126245] CDD9568 PAB0853 [NP_126970] PAB0036 [NP_125764] PAB1251 [NP_127332] endonuclease COG3780 PAB0054 [NP_125787] CDD41919 PAB1779 [NP_126559] CDD43950 PAB0176 [NP_125948] CDD43579 PAB1806 2 [NP_126515] CDD43599...”
Or search for genetic data about PF04430 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory