Family Search for PF04765 (TOD1_MUCI70)

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PF04765 hits 11 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

MUC70_ARATH / Q9FZ97 Probable hexosyltransferase MUCI70; Protein MUCILAGE-RELATED 70; EC 2.4.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 195:508 / 581 (54.0%), covers 100.0% of PF04765, 503.9 bits

• function: Probable glycosyltransferase involved in pectin and/or xylans biosynthesis in cell walls (By similarity). Together with IRX14, required for xylan and pectin synthesis in seed coat epidermal (SCE) cells (PubMed:30228108). Collaboratively with GAUT11, essential for the accumulation of seed mucilage, a gelatinous wall rich in unbranched rhamnogalacturonan I (RG I), and for shaping the surface morphology of seeds (PubMed:30228108).
  disruption phenotype: Strong reduction of seed mucilage accumulation and major decrease in rhamnogalacturonan I (RG I), associated with reduced absolute levels of rhamnose (Rha), arabinose (Ara) and galacturonic acid (GalA) but increased absolute abundance of minor sugars (e.g. galactose (Gal), xylose (Xyl), glucose (Glc) and mannose (Man)) (PubMed:30228108). The double mutant muci70-1 gaut11-3 is completely defective in seed mucilage production and exhibits a strong release of minor sugars in total mucilage extracts (PubMed:30228108). Plants missing both MUCI70 and IRX14 exhibit a severe reduction in both xylan- and pectin-related sugars in total seed mucilage extracts (PubMed:30228108).

TOD1_ARATH / Q6DBD7 Alkaline ceramidase TOD1; Protein TURGOR REGULATION DEFECT 1; EC 3.5.1.23 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q6DBD7 ceramidase (EC 3.5.1.23) from Arabidopsis thaliana (see paper)
Aligns to 103:409 / 462 (66.5%), covers 95.2% of PF04765, 377.3 bits

• function: Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH (e.g. pH 9.5) (PubMed:25591940). Inactive on phytoceramide (PubMed:25591940). Involved in the regulation of turgor pressure in guard cells and pollen tubes (PubMed:25591940).
  catalytic activity: an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine (RHEA:20856)
  disruption phenotype: Increased turgor in pollen tubes associated with altered and delayed pollen tubes growth (PubMed:25591940). Short siliques resulting from severe sterility (PubMed:25591940). Insensitivity to abscisic acid (ABA)-induced stomatal closure in guard cells (PubMed:25591940). These phenotypes are partially restored by the disruption of GAUT13 (PubMed:25591940).

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