Family Search for PF05661 (DUF808)

PF05661 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

cg1238 hypothetical protein (RefSeq) from Corynebacterium glutamicum ATCC 13032
Aligns to 3:301 / 318 (94.0%), covers 99.3% of PF05661, 425.1 bits

• Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway
  Mormann, BMC genomics 2006
  • “...1 Cysteine or Pyridoxine cg0156 (1) ROK-type transcriptional regulator Cysteine/pyridoxine biosynthesis 1 Proline or Threonine cg1238 (1) putative membrane protein 3 Methionine or Cobalamin cg1290 metE (2) Homocysteine methyltransferase Methionine biosynthesis [41] a Numbers in brackets indicate the number of clones allocated to the respective gene....”

DRO_1288 DUF808 domain-containing protein from Deinococcus radiodurans R1
DR1297, DR_1297 conserved hypothetical protein (NCBI ptt file) from Deinococcus radiodurans R1
Aligns to 3:302 / 311 (96.5%), covers 99.3% of PF05661, 410.9 bits

• Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses.
  Eugénie, Cells 2021
  • “...no/no 4 DR0561 DRO_0559 sugar ABC transporter substrate-binding protein 245 GTTCAGGAAAAAACATAAC no protein observed DR1297 DRO_1288 ABC transporter 131 GTTACGCTCCTAAACAAAT no protein observed DR2256 DRO_2230 tkt transketolase 182/199 TTTACGCCCCTAGCGTATT/ ATTCTGTCTTTACCGGAAT ND X 1,2,3 DRA0275 DRO_A0273 cytochrome C6 93 ATGTGACAAAGAGCGTAT no/no 5 Unknown function DR0219 DRO_0219 ddrF...”
• Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses.
  Eugénie, Cells 2021
  • “...ATTACGCCAAAGACGTGTT no/no 4 DR0561 DRO_0559 sugar ABC transporter substrate-binding protein 245 GTTCAGGAAAAAACATAAC no protein observed DR1297 DRO_1288 ABC transporter 131 GTTACGCTCCTAAACAAAT no protein observed DR2256 DRO_2230 tkt transketolase 182/199 TTTACGCCCCTAGCGTATT/ ATTCTGTCTTTACCGGAAT ND X 1,2,3 DRA0275 DRO_A0273 cytochrome C6 93 ATGTGACAAAGAGCGTAT no/no 5 Unknown function DR0219 DRO_0219...”
  • “...mutant, thus corroborating our data ( Figure 8 ). We were not able to detect dr1297 or dr0561 tagged proteins, but these genes encode a predicted ABC transporter and a sugar ABC transporter, respectively, containing predicted transmembrane regions or a predicted periplasmic peptide signal that could...”
• N 4-Cytosine DNA Methylation Is Involved in the Maintenance of Genomic Stability in Deinococcus radiodurans
  Li, Frontiers in microbiology 2019
  • “...repair proteins DR_1262 7.4276 1.96E-155 Ribonucleoprotein Ro/SS-A-like protein DR_B0099 3.3137 5.88E-18 Poly ADP-ribose glycohydrolase, PARG DR_1297 3.09 6.24E-12 Uncharacterized membrane protein, MutK DR_0221 2.7957 1.35E-07 Endonuclease domain-containing protein (DUF559) DR_0596 2.6105 2.51E-14 DNA helicase subunit, RuvB DR_1902 2.6449 2.96E-11 ATP-dependent RecD-like DNA helicase, RecD2 DR_2586 2.4528...”

PA1857 hypothetical protein (NCBI) from Pseudomonas aeruginosa PAO1
Aligns to 4:292 / 307 (94.1%), covers 99.7% of PF05661, 393.7 bits

• Transcriptome profiling reveals links between ParS/ParR, MexEF-OprN, and quorum sensing in the regulation of adaptation and virulence in Pseudomonas aeruginosa
  Wang, BMC genomics 2013
  • “...(4090 genes) showed similar patterns in transcript abundance. For example, genes within the region between PA1857 and PA1938 (abundant in hypothetical proteins) were expressed at a relatively low level compared with the more highly expressed genes in the chromosomal segment from PA4235 TO PA4277 (composed of...”
  • “..., oprI : outer membrane proteins; azu : azurin precursor. B . 56.6kb genome region (PA1857 to PA1938) that shows low levels of gene expression (log (RPKM+1)<2). C . 33.8kb genome region (PA4235 to PA4277) that exhibits high levels of gene expression (log (RPKM+1)>2). D ....”

BN5_0547 DUF808 domain-containing protein from Pseudomonas pseudoalcaligenes CECT 5344
Aligns to 4:294 / 308 (94.5%), covers 99.3% of PF05661, 390.0 bits

• Putative small RNAs controlling detoxification of industrial cyanide-containing wastewaters by Pseudomonas pseudoalcaligenes CECT5344
  Olaya-Abril, PloS one 2019
  • “...protease ATPase subunit HslU; BN5_0417, ATP-dependent protease subunit HslV; BN5_0418, uncharacterized protein. B. BN5_0546, azurin; BN5_0547, uncharacterized protein; BN5_0548, cytokinin riboside 5'-monophosphate phosphoribohydrolase; BN5_0549, lysine exporter protein LysE/YggA; BN5_0550, glycerophosphodiester phosphodiesterase; BN5_0551, hydrogenase/urease protein; BN5_0552, urease accessory protein UreG; BN5_0553, urease protein UreF; BN5_0554, urease accessory...”

Rv3092c PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN (NCBI) from Mycobacterium tuberculosis H37Rv
Aligns to 3:292 / 306 (94.8%), covers 99.3% of PF05661, 381.7 bits

• [MxyR of Mycobacterium tuberculosis Responds to Xylan; an Unusual Ligand for a MarR Family Transcriptional Regulator]
  Mauran, Molekuliarnaia biologiia 2022 (PubMed) (secret)
• Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
  Birhanu, Scientific reports 2019
  • “...DppA, DppC, DppD, FecB, UgpC, UgpE, ProZ, CydD, MalQ, Rv2326c, Rv2041c, Rv1680, Rv3197, Rv0987, Rv1281c, Rv3092c, Rv1747, Rv1273c, Rv1739c, Rv2564, Rv0073 Type-VII secretion EccA1, EccB1, EccCb1, EccA2, EccB2, EccC2, EccD3, EccB3, EccC4, EccB4, EccA5, EccC5, Others CpnT, NanT, IrtA, IrtB, ArsC MCE family proteins Mce2A, Mce2D,...”
• Gene inversion potentiates bacterial evolvability and virulence
  Merrikh, Nature communications 2018
  • “...GC skew values) were found in the following strains: Gene Rv1377c : Strain KIT87190, Gene Rv3092c : Strain F1, Genes emrB and purC : Strain 37004 HO genes frequently have negative GC skew values As an initial assessment of DNA inversion patterns, we calculated the chromosomal...”
• MntR(Rv2788): a transcriptional regulator that controls manganese homeostasis in Mycobacterium tuberculosis
  Pandey, Molecular microbiology 2015
  • “...7.72.1 Esat-6 like protein Rv3020c esxS 5.10.3 Esat-6 like protein Rv3061c fadE22 2.10.2 Acyl-CoA dehydrogenase Rv3092c 2.10.4 CMP Rv3094c 2.40.7 CHP Rv3095 2.10.2 Transcriptional regulator Rv3485c 2.40.7 Dehydrogenase/reductase Rv3620 esxW 3.00.9 Esat-6 like protein Rv3653 2.81.1 PE-PGRS Rv3659c 2.70.4 CHP Rv3741c 2.40.3 oxidoreductase Rv3862 whiB6 2.80.3...”
• Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients
  Sun, The Journal of infectious diseases 2012
  • “...CCG CAC - TAC 43.0 82.2 10.5 92.1 Rv2414c Rv3092c L324P H248Y Conserved hypothetical protein Conserved integral membrane protein 4358154 TAC - TAG 24.7 0...”
• Characterization of the Mycobacterium tuberculosis sigma factor SigM by assessment of virulence and identification of SigM-dependent genes
  Agarwal, Infection and immunity 2007
  • “...EsxF Conserved hypothetical proteins* SigM Rv0035 Rv0313 Rv0479c Rv0685 Rv3092c Rv3093c Rv3094c Rv3095 2.2 2.2 2.0 2.0 2.1 4.1 2.7 1.9 0.015 0.042 0.069 0.057...”
  • “...resulted in an 1.9-fold induction of genes Rv3092c, Rv3093c, Rv3094c, Rv3095, Rv3439c, Rv3440c, Rv3444c (esxT), Rv3445c (esxU), Rv3447c, Rv3449 (mycP4), Rv3904c...”

ECs2696 putative methyl-independent mismatch repair protein (NCBI ptt file) from Escherichia coli O157:H7 str. Sakai
Aligns to 6:293 / 305 (94.4%), covers 99.3% of PF05661, 378.4 bits

• Pan-genome sequence analysis using Panseq: an online tool for the rapid analysis of core and accessory genomic regions
  Laing, BMC bioinformatics 2010
  • “...presented in Table 3 , and show that the first locus selected by Panseq was ECs2696, a locus with three alleles and therefore more initial fingerprints than any other locus except ECs2006, which also had three alleles among the strains. However, ECs2696 provided more POD among...”
  • “...EC4401 EC4206 EC4196 EC4115 EC4113 EC4076 EC4045 EC4042 EC4024 EC869 EC508 EC71074 EC33264 K12 POD ECs2696 C C G C A A A A A A A A A A A A A A A 63 ECs2775 T G G G G G G G G...”

YedI / b1958 DUF808 domain-containing inner membrane protein YedI from Escherichia coli K-12 substr. MG1655 (see paper)
yedI / RF|NP_416467 inner membrane protein yedI from Escherichia coli K12 (see paper)
P46125 Inner membrane protein YedI from Escherichia coli (strain K12)
b1958 conserved inner membrane protein (NCBI) from Escherichia coli str. K-12 substr. MG1655
Aligns to 6:293 / 305 (94.4%), covers 99.3% of PF05661, 378.4 bits

• Crystallization and preliminary X-ray analysis of mannosyl-3-phosphoglycerate phosphatase from Thermus thermophilus HB27
  Gonçalves, Acta crystallographica. Section F, Structural biology and crystallization communications 2011
  • “...features with the inner membrane protein YedI (UniProtKB P46125; Arifuzzaman et al., 2006). Interestingly, in E. coli MG is taken up as...”
• Transient erythromycin resistance phenotype associated with peptidyl-tRNA drop-off on early UGG and GGG codons
  Macvanin, Journal of bacteriology 2007
  • “...yaiI ygfX argH ytfN lldP hycA Blattner no. b1600 b1958 b1186 b1193 b2524 b3354 b3824 b0654 b2258 b4539 b1317 b2277 b0638 b3564 b1746 b0387 b2896 b3960 b4221...”

c2377 Hypothetical protein yedI (NCBI ptt file) from Escherichia coli CFT073
Aligns to 6:293 / 305 (94.4%), covers 99.3% of PF05661, 378.2 bits

• Transposon-Sequencing Analysis Unveils Novel Genes Involved in the Generation of Persister Cells in Uropathogenic Escherichia coli
  Molina-Quiroz, Antimicrobial agents and chemotherapy 2016
  • “...c1925 c1927 c1945 c1956 c2004 c2034 c2144 c2199 c2232 c2377 c2385 c2465 c2471 c2475 c2615 c2677 c2702 c2841 c3028 c3174 c3255 c3721 c3888 c4475 c4704 c4725...”

VCA0930 conserved hypothetical protein (NCBI ptt file) from Vibrio cholerae O1 biovar eltor str. N16961
Aligns to 34:332 / 341 (87.7%), covers 100.0% of PF05661, 375.1 bits

• Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence
  Fontaine, ACS infectious diseases 2018
  • “...between CAI-1/AI-2 QS and c-di-GMP-induced biofilm formation. In the C1 biotype, transcription of GGDEF protein Vca0930 is positively regulated by the quorum regulatory sRNAs (Qrr), which repress translation of the HapR regulator in HapR + V. cholerae strains, further demonstrating the inverse relationship between c-di-GMP and...”
• The ins and outs of cyclic di-GMP signaling in Vibrio cholerae
  Conner, Current opinion in microbiology 2017
  • “...major pilin MshA (shown in blue). (C) The DGCs VpvC, CdgA, CdgH, CdgL, CdgK, and VCA0930, and the PDEs RocS, MbaA, CdgC, CdpA, VC1851, and CdgJ regulate c-di-GMP levels and regulate V. cholerae biofilm formation. C-di-GMP is bound by the transcription factors VpsT and VpsR. C-di-GMP...”

XOO0109 hypothetical protein (NCBI) from Xanthomonas oryzae pv. oryzae KACC10331
Aligns to 4:299 / 313 (94.6%), covers 99.3% of PF05661, 367.9 bits

• KdgR, an IClR family transcriptional regulator, inhibits virulence mainly by repression of hrp genes in Xanthomonas oryzae pv. oryzae
  Lu, Journal of bacteriology 2011
  • “...hrcU (Xoo0091), hrpB1 (Xoo0090), hrcV (Xoo0092), and hrpF (Xoo0109), in the Xoo0310 mutant cultured in hrp-inducing XOM2 broth was 17- to 60-fold higher than...”

APJL_1024 inner membrane protein (RefSeq) from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Aligns to 4:281 / 289 (96.2%), covers 99.3% of PF05661, 348.0 bits

• Global effects of catecholamines on Actinobacillus pleuropneumoniae gene expression
  Li, PloS one 2012
  • “...protein 1.84 1.62 APJL_0758 - hypothetical protein 1.98 1.62 APJL_0773 - hypothetical protein 2.28 2.07 APJL_1024 - inner membrane protein 2.54 1.86 APJL_1143 pfkA phosphofructokinase 2.84 2.62 APJL_1398 - hypothetical protein 1.75 1.60 APJL_1942 - Zn-dependent protease with chaperone function 1.58 1.56 APJL_1992 - integral membrane...”
  • “...both hormones) might have a role in catecholamine transport. Two other genes encoding membrane proteins (APJL_1024 and APJL_1992) were also regulated by Epi and NE, but the functions of these genes are unknown. Responses to catecholamine were also possibly mediated by two-component signal transduction systems (TCSTS)....”

lpg0166 Hypothetical protein (NCBI) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Aligns to 4:279 / 294 (93.9%), covers 89.8% of PF05661, 339.7 bits

• Identification of differentially expressed Legionella genes during its intracellular growth in Acanthamoeba
  Quan, Heliyon 2020
  • “...lpg0797 3.828 tRNA-Met lpg0146 3.807 transposase B, TnpA mutL 3.715 DNA mismatch repair protein MutL lpg0166 3.655 hypothetical protein lpg0433 3.637 hypothetical protein lpg0189 3.554 hypothetical protein lpg0705 3.527 transporter component lpg0039 3.503 hypothetical protein Figure2 The STRING network of alkylhydroperoxidase and their expression levels. The...”
• Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages
  Faucher, Frontiers in microbiology 2011
  • “...T6 1 T18 1 lpg2527 Contains coiled coil domain, Icm/Dot effector 2.6 3.1 5.2 6.7 lpg0166 Hypothetical (integral membrane protein) 2.6 5.9 5.8 6.4 lpg0152 Acetyltransferase, GNAT family, putative 3.8 4.0 6.0 6.0 lpg1636 Acetyltransferase, GNAT family, putative 5.4 5.1 3.7 5.9 lpg1987 Phosphohistidine phosphatase, putative...”
• bdhA-patD operon as a virulence determinant, revealed by a novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection
  Aurass, Applied and environmental microbiology 2009
  • “...homolog (organism) E value lpg0026 lpg0072 lpg0129 lpg0166 lpg0200 lpg0230 lpg0233 lpg0237 lpg0243 lpg0265 lpg0277 lpg0493 lpg0515 lpg0549 lpg0599 lpg0618...”

NGO0290 hypothetical protein (NCBI) from Neisseria gonorrhoeae FA 1090
Aligns to 4:211 / 246 (84.6%), covers 68.0% of PF05661, 263.6 bits

• MtrR modulates rpoH expression and levels of antimicrobial resistance in Neisseria gonorrhoeae
  Folster, Journal of bacteriology 2009
  • “...1.55 1.75 2.00 MtrR activated NGO0113 NGO0150 NGO0290 NGO0481 NGO0739 NGO0876 NGO1024 NGO1059 NGO1062 NGO1097 NGO1420 NGO1460 NGO1488 NGO1511 NGO1722 NGO1728...”
  • “...NGO1759 NGO1760 NGO1874 NGO1897 NGO2135 rng NGO0150 NGO0290 NGO0481 NGO0739 NGO0876 NGO1024 NGO1059 NGO1062 NGO1097 abpE NGO1460 NGO1488 NGO1511 recQ NGO1728...”

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