Family Search for PF05832 (DUF846)
PF05832 hits 11 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
NP_057162 Golgi apparatus membrane protein TVP23 homolog B isoform a from Homo sapiens
Aligns to 32:174 / 205 (69.8%), covers 100.0% of PF05832, 184.9 bits
Q8IQC1 Uncharacterized Golgi apparatus membrane protein-like protein CG5021 from Drosophila melanogaster
Aligns to 36:177 / 223 (63.7%), covers 99.3% of PF05832, 182.4 bits
SPBC2A9.05c DUF846 family protein (RefSeq) from Schizosaccharomyces pombe
Aligns to 46:184 / 219 (63.5%), covers 100.0% of PF05832, 167.3 bits
TVP23_ARATH / Q8LEK2 Golgi apparatus membrane protein-like protein ECHIDNA from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
NP_563842 golgi apparatus membrane protein-like protein ECHIDNA protein from Arabidopsis thaliana
AT1G09330 hypothetical protein (RefSeq) from Arabidopsis thaliana
Aligns to 15:155 / 186 (75.8%), covers 99.3% of PF05832, 160.8 bits
- function: Mediates trans-Golgi-network trafficking and cell elongation (PubMed:21512130, PubMed:23832588). Required for keeping the appropriate balance between secretory trafficking and vacuolar targeting of a subset of proteins (PubMed:21512130). The ECH/YIP4 complex is involved in the modulation of the trans-Golgi network (TGN)- mediated trafficking of some proteins and cell wall components (e.g. pectin and hemicellulose) to the cell wall in dark-grown hypocotyls and in secretory cells of the seed coat (PubMed:23832588).
subunit: Component of a trans-Golgi network (TGN)-localized ECH/YIP4 complex made of ECH, YIP4A and YIP4B (PubMed:23832588). Interacts directly with YIP4A and YIP4B (PubMed:23832588).
disruption phenotype: Severe size reduction of all organs (PubMed:21512130, PubMed:23832588). Abnormal cell wall composition (PubMed:23832588). - ECHIDNA protein impacts on male fertility in Arabidopsis by mediating trans-Golgi network secretory trafficking during anther and pollen development.
Fan, Plant physiology 2014 - GeneRIF: ECH expression is critical for a variety of aspects of male reproduction, including the production of functional pollen grains, their effective release, germination, and tube formation.
- Trans-Golgi network localized ECHIDNA/Ypt interacting protein complex is required for the secretion of cell wall polysaccharides in Arabidopsis.
Gendre, The Plant cell 2013 - GeneRIF: Data indicate that YIP4a (AT2G18840)/YIP4b (At4g30260)/ECH (ECHIDNA; At1g09330) complex is required for cell wall polysaccharide secretion.
- ECHIDNA-mediated post-Golgi trafficking of auxin carriers for differential cell elongation.
Boutté, Proceedings of the National Academy of Sciences of the United States of America 2013 - GeneRIF: ECH protein is required for the trans-Golgi network-mediated trafficking of the auxin influx carrier AUX1 to the plasma membrane. [ECH]
- The plant trans-Golgi network component ECHIDNA regulates defense, cell death, and endoplasmic reticulum stress
Liu, Plant physiology 2023 - “...data from this article can be found in the GenBank/EMBL data libraries under accession numbers: AT1G09330 (ECH), AT2G14610 (PR1), AT5G44420 (PDF1.2a), AT3G11820 (PEN1), AT1G59870 (PEN3), AT2G18960 (PMA or AHA1), AT1G74710 (SID2 or ICS1), AT2G46370 (JAR1), AT5G03280 (EIN2), and AT4G03550 (PMR4). Supplemental data The following materials are...”
- Asymmetric distribution of extracellular matrix proteins in seed coat epidermal cells of Arabidopsis is determined by polar secretion
Lee, Plant direct 2021 - “...in the GenBank/European Molecular Biology Laboratory databases under the following accession numbers: MUM2 (At5g63800), ECHIDNA (At1g09330), ASPG1 (At3g18490), RD21A (At1g47128), SCPL35 (At5g08260), ARA12 (At5g67360), VAMP721 (At1g04750), VAMP722 (At2g33120). 3 RESULTS 3.1 MUM2 is distributed in a polar manner in seed coat epidermal cells but not in...”
- Arabidopsis ECHIDNA protein is involved in seed coloration, protein trafficking to vacuoles, and vacuolar biogenesis
Ichino, Journal of experimental botany 2020 - “...Genome Initiative locus identifiers for the genes mentioned in this study are as follows: ECHIDNA, At1g09330; GFS9, At3g28430; VAMP711, At4g32150; ARA7, At4g19640. Results ECHIDNA is involved in seed coloration Previously, we reported a molecular link between membrane trafficking and flavonoid accumulation in the vacuole ( Ichino...”
- SYNERGISTIC ON AUXIN AND CYTOKININ 1 positively regulates growth and attenuates soil pathogen resistance
Hurný, Nature communications 2020 - “...complex with YIP4a ( At2g18840 ) and YIP4b ( At4g30260 ) homologs and Echidna (ECH; At1g09330 ) integral membrane protein 34 , 35 , we included them in our subsequent detailed interaction studies. A Yeast two-hybrid assay (Y2H) revealed a strong interaction between SYAC1 and all...”
- Identification of trans-golgi network proteins in Arabidopsis thaliana root tissue
Groen, Journal of proteome research 2014 - “...(At5g26240), Scamp1 and 2 (At2g20840, At1g03550), GAUT10 (At2g20807), putative uncharacterized protein At4g21700 (At4g21700), and ECHIDNA (At1g09330). Using the optimized value of k = 3, the three independent k -NN experiments for the LOPIT 1, 2A, and 2B data sets were conducted, and unknown proteins were assigned...”
- “...1 phenoDisco Results a protein ID protein description 1 At5g44790 Ran1 2 At2g28520 VHA-a1 3 At1g09330 ECHIDNA 4 At3g26520 aquaporinTIP1-2 5 At4g12650 endomembranefamilyprotein70 6 At5g18520 put.lung7transmemb.receptor 7 At1g52780 put.uncharac.protein 8 At1g61670 lung7transmemb.receptorfamilyprotein a Proteins that were identified by the phenoDisco algorithm to belong to the same...”
- Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis
Drakakaki, Cell research 2012 - “...Tables S1 and S2). Two of these proteins, AT1G09330 (proposed name: ECHIDNA [60]) and AT2G45010), were selected for further colocalization experiments, on the...”
- “...with SYP61-CFP (Figure 5D-5I). TVP23p, the yeast homolog of AT1G09330, is localized to late Golgi compartments and interacts with Yip4 and Yip5 [62]. Since the...”
- Comparative transcriptomic analysis of roots of contrasting Gossypium herbaceum genotypes revealing adaptation to drought
Ranjan, BMC genomics 2012 - “...zone of the root as compared with sensitive genotype. The genes encoding tonoplast intisic protein (AT1G09330), cytosolic phosphoglucomutase (AT1G23190), ketoacyl-CoA synthase (AT2G26640), 26S proteasome (AT4G24820), and cellulose synthase (AT5G05170) were expressed in tolerant genotype. Similarly, the genes encoding phosphogluconate dehydrogenase (AT1G64190), aldehyde dehydrogenase (AT1G74920), and tetratricopeptide...”
- Conserved Arabidopsis ECHIDNA protein mediates trans-Golgi-network trafficking and cell elongation
Gendre, Proceedings of the National Academy of Sciences of the United States of America 2011 - “...tremula x P. tremuloides) (13-15). This analysis identified At1g09330 to be consistently expressed at higher levels in all of the datasets in tissues and...”
- “...insertion (SAIL_163_E09) in the homologous Arabidopsis sequence (At1g09330) was analyzed. Based on its phenotypic appearance, we named the mutant line echidna...”
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LOC106757661 Golgi apparatus membrane protein-like protein ECHIDNA from Vigna radiata var. radiata
Aligns to 12:152 / 183 (77.0%), covers 99.3% of PF05832, 160.8 bits
- Genome-wide Association Study for Yield and Yield-Related Traits in Diverse Blackgram Panel (Vigna mungo L. Hepper) Reveals Novel Putative Alleles for Future Breeding Programs
Singh, Frontiers in genetics 2022 - “...CpP LOC106775061 131.587 DDB1- and CUL4-associated factor 13 Q.SpP.3 SpP LOC106757271 71.381 galactinol synthase 2 LOC106757661 95.044 Golgi apparatus membrane protein-like protein ECHIDNA LOC106756994 100.043 alkaline/neutral invertase A, mitochondrial Q.SpP.6 SpP LOC106765120 64.962 dihydrofolate synthetase Q.SpP.8.2 SpP LOC106770299 147.684 ethylene-responsive transcription factor 1B-like Q.YpP.4.1 YpP LOC106759105...”
- “...receptor-like protein 12 and polygalacturonase-like enzyme, respectively. For seeds per pod, three genes LOC106757271 (71.381kb), LOC106757661 (95.044kb) and LOC106756994 (100.043kb) were found close to the Q. SpP.3 with enzyme galactinol synthase 2, Golgi apparatus membrane enzyme-like enzyme ECHIDNA and alkaline/neutral invertase A respectively. A gene LOC106765120...”
TVP23_YEAST / P38962 Golgi apparatus membrane protein TVP23; TLG2 compartment vesicle protein of 23 kDa from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
NP_010369 Tvp23p from Saccharomyces cerevisiae S288C
YDR084C Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern (RefSeq) from Saccharomyces cerevisiae
Aligns to 15:156 / 199 (71.4%), covers 100.0% of PF05832, 160.3 bits
- function: Golgi membrane protein involved in vesicular trafficking.
subunit: Interacts with YIP4 and YIP5. - TVP23 interacts genetically with the yeast SNARE VTI1 and functions in retrograde transport from the early endosome to the late Golgi.
Stein, The Biochemical journal 2009 (PubMed)- GeneRIF: The results indicate that Tvp23p performs a partially redundant function in retrograde transport from the early endosome to the late Golgi.
- Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2-containing Golgi/endosome compartments of Saccharomyces cerevisiae.
Inadome, Experimental cell research 2007 (PubMed)- GeneRIF: Tvp proteins collectively assist in the effective maintenance/function of the late Golgi/endosomal compartments.
- Widespread Cumulative Influence of Small Effect Size Mutations on Yeast Quantitative Traits
Hua, Cell systems 2018 - “...YPR091C, YDR056C, YLL028W, YLR330W, YBL010C, YNR019W, YGL124C, YDR294C, YNL046W, YDR519W, YKR088C, YLR042C, YKL094W, YCR048W, YCR043C, YDR084C, YKR067W, YJL196C, YLL061W, YML101C, YDL232W, YOL030W, YMR054W, YDR410C, YBR273C, YLR120C, YHR110W, YOR044W, YDL137W, YJL171C, YOR285W, YMR029C, YLR064W, YPL137C, YOR092W, YBR159W, YGL083W, YNL156C, YDL128W, YBR296C, YOR175C, YJL198W, YOL101C, YHL019C, YJL117W, YGR263C,...”
- Selective inhibition of yeast regulons by daunorubicin: a transcriptome-wide analysis
Rojas, BMC genomics 2008 - “...HHO1 RIB4 YGR161C GDH1 CDC60 RPO26 YDR060W YOL124C AMS1 HMT1 RIP1 YHL021C GLT1 COP1 RPS11B YDR084C YOR021C ARA1 HOR2 RME1 YHM1 NUP82 CPR6 RPS19A YDR098C-B YOR262W ARG1 HSP104 RNR1 YHR087W PFK1 DIB1 RPS26A YDR154C YOR343C-A ARG4 HSP12 SCM4 YIL011W PHB1 DPB4 RPS4B YDR210C-D YOR343C-B ARG5 HSP26...”
- PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs
Pitre, BMC bioinformatics 2006 - “...YMR197C YOR036W YBL050W YPR185W YGR120C YPR105C YKL103C YAL034W YGR120C YBL026W YDL160C YEL015W YLR423C YGR113W YIL144W YDR084C YGL198W YPL095C YLR045C YCL029C YER016W...”
- A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p)
Millson, Eukaryotic cell 2005 - “...trafficking YLR078c YAL042w YOR036w YKL006c-a YOL018c YDR084c YJR044c YGL161c Known or putative membrane transporters YBR132c YGR289c Miscellaneous YCR048w...”
- Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network
Brun, Genome biology 2003 - “...Vesicular transport Unknown YDR100W 56 Vesicular transport Unknown YDR425W 56 Vesicular transport (1) Protein, transport YDR084C 56 Vesicular transport Unknown YGL198W 56 Vesicular transport Unknown YPL246C 56 Vesicular transport Unknown YLR285W 57 Vesicular transport (0) (0) Chromatin silencing at ribosomal DNA, nicotinamide metabolism =, , ,...”
- Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes
Hettema, The EMBO journal 2003 - “...been detected in two-hybrid screens, including Apg17p, Ygl161c, Ygl198w, Ydr084c, Yjr110w and Yhr022c (Uetz et al., 2000; Ito et al., 2001), but none of these...”
- Recognition of protein coding genes in the yeast genome at better than 95% accuracy based on the Z curve
Zhang, Nucleic acids research 2000 - “...YAR047c YDR065w YGL041c YJL108c YLR394w YOL079w YAR053w YDR084c YGL054c YJL118w YLR400w YOL101c YAR060c YDR102c YGL084c YJL136w-a YLR402w YOL107w YAR061w...”
Q5W723 Golgi apparatus membrane protein TVP23 from Oryza sativa subsp. japonica
Aligns to 12:152 / 187 (75.4%), covers 99.3% of PF05832, 159.5 bits
LOC105135664 Golgi apparatus membrane protein-like protein ECHIDNA from Populus euphratica
Aligns to 12:152 / 183 (77.0%), covers 99.3% of PF05832, 156.9 bits
- Genetic Architecture of Heterophylly: Single and Multi-Leaf Genome-Wide Association Mapping in Populus euphratica
Zhu, Frontiers in plant science 2022 - “...1-associated receptor kinase 1-like 348192 Ovoid PC3 LOC105111727 Downstream Protein CHUP1, chloroplastic 364173 Broad-ovate PC4 LOC105135664 Downstream Golgi apparatus membrane protein-like protein ECHIDNA 132098 Broad-ovate PC1 LOC105114785 Non_coding_transcript LRR receptor-like serine/threonine-protein kinase GSO1 258505 Broad-ovate PC2 LOC105109333 Upstream Zeaxanthin epoxidase, chloroplastic-like 292655, 292661 TABLE 2 Candidate...”
- “...hypothesized that the P. euphratica ARF19 protein may similarly regulate leaf development. Several genes, including LOC105135664, LOC105115855, LOC105117940, LOC105117941, and LOC105110388, may control leaf size by regulating cell division and expansion ( Table 1 ). Multi-leaf GWAS identified 21 genes with SNPs associated with variation in...”
NP_660344 Golgi apparatus membrane protein TVP23 homolog C isoform 1 from Homo sapiens
Q96ET8 Golgi apparatus membrane protein TVP23 homolog C from Homo sapiens
Aligns to 32:167 / 276 (49.3%), covers 85.6% of PF05832, 152.1 bits
NP_001343450 Golgi apparatus membrane protein TVP23 homolog B isoform 3 precursor from Mus musculus
Aligns to 1:110 / 141 (78.0%), covers 76.3% of PF05832, 143.5 bits
K7EK95 Golgi apparatus membrane protein TVP23 homolog (Fragment) from Homo sapiens
Aligns to 1:56 / 60 (93.3%), covers 34.5% of PF05832, 41.6 bits
Or search for genetic data about PF05832 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory