Family Search for PF06073 (DUF934)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF06073 hits 28 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

PA1837 hypothetical protein from Pseudomonas aeruginosa PAO1
Aligns to 55:161 / 165 (64.8%), covers 100.0% of PF06073, 154.2 bits

• Searching for Biological Function of the Mysterious PA2504 Protein from Pseudomonas aeruginosa
  Drabinska, International journal of molecular sciences 2021
  • “...Alkaline metalloproteinase PA1493 cysP 0.55 Sulphate ABC transporter substrate-binding protein PA1756 cysH 0.98 Phosphoadenosinephosphosulphate reductase PA1837 PA1837 1.52 Hypothetical protein/ oxidoreductase probably involved in sulphite reduction PA1838 cysI 1.29 Sulphite reductase PA1912 femI 0.39 ECF sigma factor FemI PA2062 PA2062 1.00 Probable pyridoxal-phosphate dependent protein/ IscS...”
• The LysR-Type Transcriptional Regulator BsrA (PA2121) Controls Vital Metabolic Pathways in Pseudomonas aeruginosa
  Modrzejewska, mSystems 2021
  • “...180 07670 PA3488 305 07670 PA3488 2.09 2.45 Hypothetical protein 410 16485 PA1838 7 16490 PA1837 2.10 2.02 DUF934 domain-containing protein 348 13300 PA2440 374 13295 PA2441 2.10 2.45 Hypothetical protein 389 15535 PA2020 72 15535 PA2020 2.11 2.50 MexZ, transcriptional regulator 652 25380 PA4673.1 28...”
• Traditional Chinese Medicine Tanreqing Inhibits Quorum Sensing Systems in Pseudomonas aeruginosa
  Yang, Frontiers in microbiology 2020
  • “...Alkaline proteinase inhibitor AprI PA1384 galE 1.3 UDP-glucose 4-epimerase PA1784 1.2 1.6 + Hypothetical protein PA1837 2 Hypothetical protein PA1838 cysI 1.5 Sulfite reductase PA1869 acp1 2.4 2.2 + Acp1 PA1871 lasA 2 3.4 + LasA protease precursor PA1899 phzA2 2.1 2.8 Probable phenazine biosynthesis protein...”
• Molecular mechanism for sphingosine-induced Pseudomonas ceramidase expression through the transcriptional regulator SphR
  Okino, Scientific reports 2016
  • “...cysN ATP sulfurylase GTP-binding subunit/APS kinase 2.294 0.0304196 PA2426 pvdS sigma factor PvdS 2.285 0.0049072 PA1837 hypothetical protein 2.271 0.0095659 PA4351 OlsA 2.238 0.0282751 PA0280 cysA sulfate transport protein CysA 2.171 0.0079830 PA0843 plcR phospholipase accessory protein PlcR precursor 2.074 0.0009660 PA0844 plcH hemolytic phospholipase C...”
• A theoretical and experimental proteome map of Pseudomonas aeruginosa PAO1
  Lecoutere, MicrobiologyOpen 2012
  • “...54 * PA1800 tig Trigger factor O C 48.6 54 4.83 4.76 0.699 0.395 55 PA1837 Hypothetical protein S C 18.8 19 4.88 4.88 0.69 0.378 56 PA2001 atoB Acetyl CoA acetyltransferase I C 40.4 40 6.03 6.02 0.716 0.121 57 PA2064 pcoB Copper resistance protein...”
  • “...Pseudomonas database, 12 of which so far lacked experimental confirmation (PA0446, PA0664, PA0976, PA1597, PA1677, PA1837, PA2806, PA3302, PA3481, PA3801, PA4458, and PA5339). Among those 19 proteins, 12 are conserved in other organisms. Obviously, their substantial expression suggests that they have biological roles in P. aeruginosa...”
• Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence
  Lee, Microbial biotechnology 2009
  • “...1.3 Hypothetical protein PA0939 1.1 5.3 1.6 Hypothetical protein PA1190 5.7 1.6 1.2 Hypothetical protein PA1837 4.6 2.1 1.1 Hypothetical protein PA1914 1.1 6.1 1.1 Hypothetical protein PA1953 3.2 6.1 1.5 Hypothetical protein PA2036 2.0 7.0 1.1 Hypothetical protein PA2078 3.0 5.7 1.6 Hypothetical protein PA2419...”

Psyr_2461 Uncharacterised conserved protein UCP030820 from Pseudomonas syringae pv. syringae B728a
Aligns to 55:161 / 164 (65.2%), covers 100.0% of PF06073, 153.5 bits

• Genome-wide identification of Pseudomonas syringae genes required for fitness during colonization of the leaf surface and apoplast
  Helmann, Proceedings of the National Academy of Sciences of the United States of America 2019 (secret)

PP_2370 conserved hypothetical protein from Pseudomonas putida KT2440
Aligns to 55:161 / 164 (65.2%), covers 100.0% of PF06073, 152.5 bits

• Production of selenium nanoparticles occurs through an interconnected pathway of sulphur metabolism and oxidative stress response in Pseudomonas putida KT2440
  Avendaño, Microbial biotechnology 2023
  • “...Cmethyltransferase Sulphur metabolism/Porphyrins Delayed RF31 PP_3999 cysG UroporphyrinIII Cmethyltransferase JJ3 PP_3999 cysG UroporphyrinIII Cmethyltransferase JJ7 PP_2370 Hypothetical conserved protein Sulphur metabolism JJ13 PP_0051 sqrR Putative dependant sigma54 transcriptional regulator Fast JJ33 PP_0052 pdo2 Persulphide dioxygenase JJ14 PP_0053 sqr Sulphidequinone oxidoreductase RF16 PP_4189 sucA 2oxoglutarate dehydrogenase Central...”
  • “...related to selenium metabolism were obtained (Table 1 ). Twelve mutants (in genes cysG , PP_2370, sucA , D2HGDH , gqr , ccmF , ldcA , msbA and wzy ) had a phenotype delayed in the production of elemental selenium nanoparticles, meaning that the colonies had...”

AO356_00560 required for sulfate utilization, putative electron transport protein for sulfite reductase from Pseudomonas fluorescens FW300-N2C3
Aligns to 55:161 / 164 (65.2%), covers 100.0% of PF06073, 152.4 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase, auxotrophic

PfGW456L13_2842 required for sulfate utilization, putative electron transport protein for sulfite reductase from Pseudomonas fluorescens GW456-L13
Aligns to 55:161 / 164 (65.2%), covers 100.0% of PF06073, 152.2 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

Pf6N2E2_2074 required for sulfate utilization, putative electron transport protein for sulfite reductase from Pseudomonas fluorescens FW300-N2E2
Aligns to 55:161 / 164 (65.2%), covers 100.0% of PF06073, 151.2 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

BTH_I0815 Bacterial protein of unknown function (DUF934) superfamily from Burkholderia thailandensis E264
Aligns to 61:167 / 180 (59.4%), covers 100.0% of PF06073, 147.4 bits

• Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264
  Mao, Proceedings of the National Academy of Sciences of the United States of America 2017
  • “...BTH_II2095 BTH_II2097 BTH_II1237 BTH_II2099 BTH_I0892 BTH_I0815 BTH_II2098 BTH_I1051 BTH_II1240 BTH_II1238 BTH_II2094 BTH_II1241 BTH_II1239 BTH_I0814 Fold...”

RR42_RS16265 required for sulfate utilization, putative electron transport protein for sulfite reductase from Cupriavidus basilensis FW507-4G11
Aligns to 74:180 / 193 (55.4%), covers 100.0% of PF06073, 142.5 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

RSc2424 CONSERVED HYPOTHETICAL PROTEIN from Ralstonia solanacearum GMI1000
Aligns to 77:183 / 194 (55.2%), covers 100.0% of PF06073, 141.8 bits

• A CysB regulator positively regulates cysteine synthesis, expression of type III secretion system genes, and pathogenicity in Ralstonia solanacearum
  Chen, Molecular plant pathology 2022
  • “...function for sulphate transportation (Figure 3a ). A further five genes, cysI ( RSc2425 ), RSc2424 (hypothetical protein), cysH ( RSc2423 ), cysD ( RSc2422 ), and cysN ( RSc2422 ), are located together, possibly forming a cysI regulon to function for sulphate reduction (Figure 3b...”

BPHYT_RS04730 required for sulfate utilization, putative electron transport protein for sulfite reductase from Burkholderia phytofirmans PsJN
Aligns to 61:166 / 179 (59.2%), covers 99.1% of PF06073, 140.9 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

HP15_1796 required for sulfate utilization, putative electron transport protein for sulfite reductase from Marinobacter adhaerens HP15
ACP86_21365 DUF934 domain-containing protein from Marinobacter sp. CP1
Aligns to 57:163 / 168 (63.7%), covers 100.0% of PF06073, 135.5 bits

• mutant phenotype: PFam PF06073.8 (DUF934). Conserved cofitness with sulfite reductase; auxotrophic.
• Marinobacter atlanticus electrode biofilms differentially regulate gene expression depending on electrode potential and lifestyle
  Eddie, Biofilm 2021
  • “...case, the predicted sulfite reductase was co-transcribed with a putative oxidoreductase gene containing a DUF934 (ACP86_21365), which did not meet the fold change cutoff. An ortholog of this gene has been identified as being required for utilization of sulfate as a sulfur source in Marinobacter adhaerans...”

CCNA_01178 oxidoreductase from Caulobacter crescentus NA1000
Aligns to 57:162 / 168 (63.1%), covers 96.3% of PF06073, 130.8 bits

• Genome-scale fitness profile of Caulobacter crescentus grown in natural freshwater
  Hentchel, The ISME journal 2019
  • “...-0.61 CCNA_01176 DUF2849, pfam11011 -4.98 -0.81 -0.84 CCNA_01178 DUF934, pfam06073, COG3749 -4.36 -0.60 -0.64 CCNA_01676 TamB, COG2911, pfam04357 -6.40 -0.52...”

AL066_11190 DUF934 domain-containing protein from Pseudomonas nunensis
Aligns to 50:156 / 159 (67.3%), covers 100.0% of PF06073, 130.0 bits

• Transcriptomic profiling of microbe-microbe interactions reveals the specific response of the biocontrol strain P. fluorescens In5 to the phytopathogen Rhizoctonia solani
  Hennessy, BMC research notes 2017
  • “...AL066_12155 Hypothetical protein 4.6 1.7 AL066_03355 ABC transporter 4.2 1.0 AL066_27880 Cytochrome b 3.5 1.2 AL066_11190 Oxidoreductase 3.0 2.0 AL066_11490 Hypothetical protein 3.0 1.2 AL066_26360 AlpA family transcriptional regulator 3.5 3.3 AL066_11195 Sulfite reductase 3.5 2.0 AL066_13155 NIPSNAP domain containing protein 4.1 1.3 AL066_11200 Cytochrome C...”

PA4129 hypothetical protein from Pseudomonas aeruginosa PAO1
Aligns to 53:159 / 162 (66.0%), covers 98.1% of PF06073, 127.8 bits

• The secondary metabolite hydrogen cyanide protects Pseudomonas aeruginosa against sodium hypochlorite-induced oxidative stress
  da, Frontiers in microbiology 2023
  • “...0.359 7.617 0.615 PA3022 PA3022 PW6063 9.181 0.331 7.228 2.425 PA14_24980 8.038 0.505 6.325 1.978 PA4129 PA4129 PW7993 9.113 0.397 6.482 1.977 PA4130 PA4130 PW7996 9.290 0.083 7.835 0.936 PA14_10550 6.401 0.398 6.176 0.577 PA4131 PA4131 PW7998 9.367 0.115 7.331 0.316 PA14_10540 8.238 0.105 7.278 0.483...”
• A VirB4 ATPase of the mobile accessory genome orchestrates core genome-encoded features of physiology, metabolism, and virulence of Pseudomonas aeruginosa TBCF10839
  Wiehlmann, Frontiers in cellular and infection microbiology 2023
  • “...T6SS) 29.5 PA3908 tsiT, immunity protein, TsiT (part of T6SS) 173.7 PA3928 Hypothetical protein 7.5 PA4129 Hypothetical protein 16.6 PA4130 nirA, ferredoxin-dependent nitrite reductase, NirA 24.2 PA4132 mpaR, MvfR-mediated PQS, and anthranilate regulator MpaR 8.1 PA4133 Cytochrome c oxidase subunit (cbb3-type) 40.6 PA4134 Hypothetical protein 35.3...”
• NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
  Fenn, mBio 2021
  • “...hypothetical protein with homology to nitrite and sulfite reductases, and forming a predicted operon with PA4129 ( Fig.1E ). To ensure the attenuation in virulence traits observed was not due a polar effect on PA4129, located in the same predicted transcriptional unit as PA4130, in-frame deletion...”
  • “...incubated at 37C for 16h. (E) Diagram displaying operon structure and transcriptional start sites of PA4129- PA4130 and PA4131- PA4132 with the PAJD21 Tn 5 insertion site indicated by the red arrow. Data were collated from three independent experiments with at least three replicates each. Values...”
• Traditional Chinese Medicine Tanreqing Inhibits Quorum Sensing Systems in Pseudomonas aeruginosa
  Yang, Frontiers in microbiology 2020
  • “...terminal oxidase PA4078 2.1 3.9 + Probable non-ribosomal peptide synthetase PA4079 1.4 NaD(P)H-dependent carbonyl reductase PA4129 2.1 2.1 + Hypothetical protein PA4130 2.5 2 + Probable sulfite or nitrite reductase PA4131 2.3 1.9 + Probable ironsulfur protein PA4132 1.9 1.9 + Conserved hypothetical protein PA4133 4.2...”
• Conditional quorum-sensing induction of a cyanide-insensitive terminal oxidase stabilizes cooperating populations of Pseudomonas aeruginosa
  Yan, Nature communications 2019
  • “...the presence of 150M KCN; grid, in the absence of 150M KCN. b cioA , PA4129, PA4131, PA4133, and rhdA expression from either WT PAO1 (policing, black) or RhlR-null cooperators (non-policing, white) when grown in co-culture with cheaters, with the populations separated by dialysis membranes. Expression...”
  • “...cooperators in these experiments with dialysis membranes and compared expression by cooperators of cioA , PA4129, PA4131, PA4133, or rhdA in both the policing and non-policing conditions. We added analysis of PA4129 and PA4131 in this analysis because differences in PA4133 expression were markedly different than...”
• A novel cyanide-inducible gene cluster helps protect Pseudomonas aeruginosa from cyanide
  Frangipani, Environmental microbiology reports 2014 (PubMed)
  • “...These genes are predicted to encode hypothetical proteins (PA4129, PA4132 and PA4134), proteins possibly involved in electron transfer (PA4131 and PA4133), and...”
  • “...translational fusion. This choice was made as PA4130 and PA4129 are homologues of two genes that form a transcriptional unit together with cioAB in P....”
• Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon
  Chugani, Proceedings of the National Academy of Sciences of the United States of America 2012
  • “...PA3332 PA3475 PA3476 PA3535 PA3724 PA3904 PA3907 PA4128 PA4129 PA4130 PA4131 PA4132 PA4134 PA4677 clpP2 pheC rhlI lasB Description RahU Chitin-binding protein...”
• Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa
  Jakobsen, Applied and environmental microbiology 2012
  • “...PA3361 PA3477 PA3478 PA3479 PA3520 PA3692 PA3724 PA3923 PA4129 PA4130 PA4131 PA4132 PA4133 PA4134 PA4141 PA4142 PA4175 PA4209 PA4211 PA4217 PA4738 PA4739 PA5170...”
• More

Ga0059261_1499 required for sulfate utilization, putative electron transport protein for sulfite reductase from Sphingomonas koreensis DSMZ 15582
Aligns to 32:137 / 142 (74.6%), covers 100.0% of PF06073, 126.4 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

CLJ1_0708 DUF934 domain-containing protein from Pseudomonas aeruginosa
Aligns to 53:159 / 162 (66.0%), covers 98.1% of PF06073, 126.4 bits

• Insertion sequences drive the emergence of a highly adapted human pathogen
  Sentausa, Microbial genomics 2020
  • “...cluster are found a putative sulfite reductase-encoding gene ( CLJ1_0707 ) and a gene ( CLJ1_0708 ) coding for an oxidoreductase probably involved in sulfite reduction; however, their exact role is unknown. Fig. 5. Expression of virulence factors and pathogenicity. (a) The hcn operon in CLJ1...”

PA14_10560 hypothetical protein from Pseudomonas aeruginosa UCBPP-PA14
Aligns to 53:159 / 162 (66.0%), covers 98.1% of PF06073, 125.5 bits

• Evolution of biofilm-adapted gene expression profiles in lasR-deficient clinical Pseudomonas aeruginosa isolates
  Jeske, NPJ biofilms and microbiomes 2022
  • “...PA14_34810 mxaA PA14_46530 PA14_10530 PA14_34820 PA14_46540 PA14_10540 fixG PA14_34830 PA14_46550 PA14_10550 cysI PA14_34840 PA14_48040 aprI PA14_10560 PA14_34870 chiC PA14_48060 aprA PA14_13360 PA14_36310 hcnC PA14_48090 aprF PA14_13370 PA14_36320 hcnB PA14_48100 aprE PA14_13380 PA14_36330 hcnA PA14_48115 aprD PA14_13390 PA14_36530 PA14_48140 aprX PA14_15090 - PA14_36620 PA14_49260 napB PA14_16250 lasB...”
• Uracil influences quorum sensing and biofilm formation in Pseudomonas aeruginosa and fluorouracil is an antagonist
  Ueda, Microbial biotechnology 2009
  • “...mmsA 16 1.4 11.3 Methylmalonatesemialdehyde dehydrogenase PA14_11140 PA4078 17.1 1.1 16 Probable nonribosomal peptide synthetase PA14_10560 PA4129 29.9 1.1 13.9 Hypothetical protein PA14_10550 PA4130 26 1 26 Probable sulfite or nitrite reductase PA14_10540 PA4131 18.4 1 17.1 Probable ironsulfur protein PA14_10500 PA4133 29.9 1.1 29.9 Cytochrome...”

Ac3H11_576 required for sulfate utilization, putative electron transport protein for sulfite reductase from Acidovorax sp. GW101-3H11
Aligns to 19:123 / 128 (82.0%), covers 99.1% of PF06073, 121.6 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase; auxotrophic

LPU83_2531 DUF934 domain-containing protein from Rhizobium favelukesii
Aligns to 51:157 / 170 (62.9%), covers 96.3% of PF06073, 117.0 bits

• ubiF is involved in acid stress tolerance and symbiotic competitiveness in Rhizobium favelukesii LPU83
  Martini, Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 2022
  • “...mutant Tn833 carrying a singletransposon insertion within LPU83_2531, an uncharacterized short ORF located immediately upstream from ubiF homolog. This gene...”
  • “...As the transposon was inserted near the 3 end of LPU83_2531 and these genes are cotranscribed as a part of the same operon, we hypothesized that the phenotype...”

BCAM1677 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 31:136 / 145 (73.1%), covers 94.4% of PF06073, 116.4 bits

• Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum
  Drevinek, BMC infectious diseases 2008
  • “...reactive oxygen and nitrogen species upregulated BCAL1766 2.23 OsmC-like protein BCAM1676 19.99 putative nitrite/sulfite reductase BCAM1677 26.75 conserved hypothetical protein BCAM2753 8.00 putative organic hydroperoxide resistance protein, ohr gene Downregulated (none) Motility and adherence upregulated BCAL0124 2.02 flagellar regulon master regulator subunit FlhD BCAL0525 2.17 flagellar...”
  • “...dehydrogenase BCAL1156 2.02 putative 4-hydroxybenzoate transporter BCAL1157 2.51 putative monooxygenase BCAM1676 19.99 putative nitrite/sulfite reductase BCAM1677 26.75 conserved hypothetical protein BCAM2749 31.39 carboxymuconolactone decarboxylase family protein BCAM2750 14.06 putative exported protein BCAM2751 7.13 LysR family regulatory protein BCAM2752 12.35 NAD dependent epimerase/dehydratase family protein BCAM2753 8.00...”

RL2291 hypothetical protein from Rhizobium leguminosarum bv. viciae 3841
Aligns to 51:157 / 170 (62.9%), covers 97.2% of PF06073, 114.9 bits

• The Use of Transposon Insertion Sequencing to Interrogate the Core Functional Genome of the Legume Symbiont Rhizobium leguminosarum
  Perry, Frontiers in microbiology 2016
  • “...protein RL2289 VGI 3 0.33 1 GD 3 1 19 NE 0.0.2 Conserved hypothetical protein RL2291 VGI 7 0.71 2 GD 7 0.86 20 NE 0.0.2 Conserved hypothetical protein RL2527 VGI 13 0.31 8.5 GD 13 0.69 6.78 NE 0.0.2 Conserved hypothetical exported protein RL4728 VGI...”

SMc02123 required for sulfate utilization, putative electron transport protein for sulfite reductase from Sinorhizobium meliloti 1021
SMc02123 CONSERVED HYPOTHETICAL PROTEIN from Sinorhizobium meliloti 1021
Aligns to 51:157 / 166 (64.5%), covers 94.4% of PF06073, 113.4 bits

• mutant phenotype: PFam PF06073.8 (DUF934). conserved cofitness with sulfite reductase (SMc02124, sometimes misannotated as nitrite reductase); auxotrophic
• Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti
  Santos, BMC microbiology 2010
  • “...J transmembrane protein 9.1 SMc01925 nuoL probable NADH dehydrogenase I chain L transmembrane protein 10.0 SMc02123 Sulfate or sulfite assimilation protein 12.6 SMc02124 cysI putative sulfite reductase 20.2 SMc02479 mdh probable malate dehydrogenase 9.9 SMc02480 sucC probable succinyl-CoA synthetase beta chain 9.4 SMc02481 sucD probable succinyl-CoA...”
• Nebulon: a system for the inference of functional relationships of gene products from the rearrangement of predicted operons
  Janga, Nucleic acids research 2005
  • “...dehydratase protein SMc00977 2 Putative acyl-COA dehydrogenase protein SMc01153 2 Probable enoyl COA hydratase protein SMc02123 2 Conserved hypothetical protein thiF 2 Putative Thiamine biosynthesis transmembrane protein typA 2 Probable GTP-binding protein ubiE 2 Probable ubiquinone/menaquinone biosntesis methyltransferase protein...”

BP3433 conserved hypothetical protein from Bordetella pertussis Tohama I
Aligns to 64:174 / 174 (63.8%), covers 95.3% of PF06073, 111.2 bits

• Combined RNAseq and ChIPseq Analyses of the BvgA Virulence Regulator of Bordetella pertussis
  Coutte, mSystems 2020
  • “...bp2226 , bp2227 , bp2232, bp2233 , bp2256, bp2257, bp2749 , bp2907 ( fhaL ), bp3433 , and bp3439 ( dnt ), identified as vag s(3) in the RNAseq analysis. 10.1128/mSystems.00208-20.6 FIGS6 Representation of the ChIPseq reads mapping on the fim2 and fim3 loci. (A) ChIPseq-mapped...”

ACIAD2981 conserved hypothetical protein from Acinetobacter sp. ADP1
Aligns to 63:168 / 172 (61.6%), covers 96.3% of PF06073, 110.0 bits

• Iterative reconstruction of a global metabolic model of Acinetobacter baylyi ADP1 using high-throughput growth phenotype and gene essentiality data
  Durot, BMC systems biology 2008
  • “...adding new complex subunits (ACIAD0799: falsely considered as a sulfite reductase subunit and replaced by ACIAD2981 after further investigations) or assigning spontaneous activity (ACIAD2819: encodes for gluconolactonase activity which has been shown to occur spontaneously [ 37 ]). See Additional file 3 for further details on...”

ABUW_0644 DUF934 domain-containing protein from Acinetobacter baumannii
Aligns to 52:157 / 161 (65.8%), covers 96.3% of PF06073, 108.6 bits

• Importance of Core Genome Functions for an Extreme Antibiotic Resistance Trait
  Gallagher, mBio 2017
  • “...4 3 5 8 8 ABUW_0643 cysI Sulfite reductase 1 3 4 4 e ND ABUW_0644 Hypothetical protein 2 0 1 8 ND ABUW_0699 Hypothetical protein 3 2 2 4 ND ABUW_0924 htpX Heat shock protein 4 3 6 4 4 ABUW_0949 Hypothetical protein 2 3...”

BMEI1764 OXIDOREDUCTASE from Brucella melitensis 16M
BCAN_A0188 uncharacterised conserved protein UCP030820 from Brucella canis ATCC 23365
Aligns to 58:161 / 174 (59.8%), covers 91.6% of PF06073, 95.9 bits

• Differential expression of iron acquisition genes by Brucella melitensis and Brucella canis during macrophage infection
  Eskra, PloS one 2012
  • “...BCAN_A0193 B12-dependent methionine synthase metH NC 2.17 BMEI1760 BCAN_A0192 hypothetical protein BMEI1760 - NC 2.17 BMEI1764 BCAN_A0188 oxidoreductase - NC 56.25 BMEI1765 BCAN_A0187 phosphoadenosine phosphosulfate reductase cysH NC 45.65 BMEI1766 BCAN_A0186 sulfite reductase ferredoxin) cysI NC 39.80 BMEI1767 BCAN_A0185 hypothetical protein BMEI1767 - NC 56.28 BMEI1768...”
• Differential expression of iron acquisition genes by Brucella melitensis and Brucella canis during macrophage infection
  Eskra, PloS one 2012
  • “...B12-dependent methionine synthase metH NC 2.17 BMEI1760 BCAN_A0192 hypothetical protein BMEI1760 - NC 2.17 BMEI1764 BCAN_A0188 oxidoreductase - NC 56.25 BMEI1765 BCAN_A0187 phosphoadenosine phosphosulfate reductase cysH NC 45.65 BMEI1766 BCAN_A0186 sulfite reductase ferredoxin) cysI NC 39.80 BMEI1767 BCAN_A0185 hypothetical protein BMEI1767 - NC 56.28 BMEI1768 BCAN_A0184...”

RSc1863 CONSERVED HYPOTHETICAL PROTEIN from Ralstonia solanacearum GMI1000
Aligns to 69:165 / 169 (57.4%), covers 71.0% of PF06073, 89.4 bits

• PrhG, a transcriptional regulator responding to growth conditions, is involved in the control of the type III secretion system regulon in Ralstonia solanacearum
  Plener, Journal of bacteriology 2010
  • “...95 genes as activated by PrhG and 1 gene (RSc1863) as repressed. The PrhG regulon largely overlaps the previously described HrpB regulon: nearly 75% of the...”

BN5_1901 DUF934 domain-containing protein from Pseudomonas oleovorans CECT 5344
W6QU90 DUF934 domain-containing protein from Pseudomonas pseudoalcaligenes (strain CECT 5344)
Aligns to 50:147 / 159 (61.6%), covers 83.2% of PF06073, 84.5 bits

• Proteomic Analysis of Arsenic Resistance during Cyanide Assimilation by Pseudomonas pseudoalcaligenes CECT 5344
  Biełło, International journal of molecular sciences 2023
  • “...CN - W6RF17 BN5_1900 Sulfite reductase (NADPH) hemoprotein beta-component CysL3 0.75 0.09 17.44 2.05 W6QU90 BN5_1901 Uncharacterized protein CioC3 NAs 0.22 CN 30.15 W6R254 BN5_1902 Terminal oxidase subunit I CioA3 - CN CN - W6QVH5 BN5_1903 Cytochrome d ubiquinol oxidase, subunit II CioB3 - - -...”
• Alternative Pathway for 3-Cyanoalanine Assimilation in Pseudomonas pseudoalcaligenes CECT5344 under Noncyanotrophic Conditions
  Pérez, Microbiology spectrum 2021
  • “...the cio gene cluster (cyanide resistance) W6RF17 BN5_1900 Sulfite reductase hemoprotein -component (CysI3) R W6QU90 BN5_1901 Uncharacterized protein (CioC) R R W6R254 BN5_1902 Terminal oxidase subunit I (CioA) R R W6QWX6 BN5_1904 Phosphoserine aminotransferase (SerC) R R W6RF21 BN5_1905 Histidinol-phosphate aminotransferase (HisC) CNA R 243.78 W6QU95...”
• Putative small RNAs controlling detoxification of industrial cyanide-containing wastewaters by Pseudomonas pseudoalcaligenes CECT5344
  Olaya-Abril, PloS one 2019
  • “...thioredoxins protein; BN5_1898, 2-dehydro-3-deoxyphosphogluconate/4-hydroxy-2-oxoglutarate aldolase; BN5_1899, GntR family transcriptional regulator; BN5_1900, sulfite reductase-NADPH hemoprotein -component; BN5_1901, uncharacterized protein; BN5_1902, terminal oxidase subunit I CioA; BN5_1903, cytochrome d ubiquinol oxidase, subunit II CioB; BN5_1904, phosphoserine/phosphohydroxythreonine aminotransferase; BN5_1905, histidinol phosphate/imidazole acetol phosphate transaminase; BN5_1906, acetylornithine aminotransferase; BN5_1907, 4-hydroxy-tetrahydrodipicolinate...”
• Proteomic Analysis of Arsenic Resistance during Cyanide Assimilation by Pseudomonas pseudoalcaligenes CECT 5344
  Biełło, International journal of molecular sciences 2023
  • “...CN CN - W6RF17 BN5_1900 Sulfite reductase (NADPH) hemoprotein beta-component CysL3 0.75 0.09 17.44 2.05 W6QU90 BN5_1901 Uncharacterized protein CioC3 NAs 0.22 CN 30.15 W6R254 BN5_1902 Terminal oxidase subunit I CioA3 - CN CN - W6QVH5 BN5_1903 Cytochrome d ubiquinol oxidase, subunit II CioB3 - -...”
• Alternative Pathway for 3-Cyanoalanine Assimilation in Pseudomonas pseudoalcaligenes CECT5344 under Noncyanotrophic Conditions
  Pérez, Microbiology spectrum 2021
  • “...by the cio gene cluster (cyanide resistance) W6RF17 BN5_1900 Sulfite reductase hemoprotein -component (CysI3) R W6QU90 BN5_1901 Uncharacterized protein (CioC) R R W6R254 BN5_1902 Terminal oxidase subunit I (CioA) R R W6QWX6 BN5_1904 Phosphoserine aminotransferase (SerC) R R W6RF21 BN5_1905 Histidinol-phosphate aminotransferase (HisC) CNA R 243.78...”

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