Family Search for PF06679 (DUF1180)

PF06679 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

TMEM157 membrane protein FAM174A precursor from Bos taurus
Aligns to 10:193 / 193 (95.3%), covers 99.4% of PF06679, 250.7 bits

• Genomic Prediction of Breeding Values Using a Subset of SNPs Identified by Three Machine Learning Methods
  Li, Frontiers in genetics 2018
  • “...1 4 7574 ARS-BFGL-NGS-1712 63,120,929 0.79 0 BMPER 2 7 13739 ARS-BFGL-NGS-59783 101,669,109 0.44 558,040 TMEM157 3 21 32659 BTA-119902-no-rs 63,088,634 0.3943 56,593 PAPOLA 4 13 22207 ARS-BFGL-NGS-10111 15,828,258 0.39 156,328 GATA3 5 29 38788 Hapmap60043-rs29009948 11,619,866 0.37 0 DLG2 6 30 39467 BTA-24571-no-rs 4,845,661 0.35...”

XP_023473694 membrane protein FAM174A isoform X1 from Equus caballus
Aligns to 10:192 / 192 (95.3%), covers 99.4% of PF06679, 247.6 bits

• Preliminary analysis of the FAM174A gene suggests it lacks a strong association with equine metabolic syndrome in ponies.
  Cash, Domestic animal endocrinology 2020 (PubMed)
  • GeneRIF: Preliminary analysis of the FAM174A gene suggests it lacks a strong association with equine metabolic syndrome in ponies.
• Assessment of the FAM174A 11G allele as a risk allele for equine metabolic syndrome.
  Roy, Animal genetics 2020 (PubMed)
  • GeneRIF: Assessment of the FAM174A 11G allele as a risk allele for equine metabolic syndrome.

NP_940909 membrane protein FAM174A precursor from Homo sapiens
Q8TBP5 Membrane protein FAM174A from Homo sapiens
Aligns to 10:190 / 190 (95.3%), covers 99.4% of PF06679, 245.3 bits

• NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1.
  Li, Biochemical and biophysical research communications 2016 (PubMed)
  • GeneRIF: NS5ATP6 regulates the intracellular triglyceride level via FGF21, and independently of SIRT1 and SREBP1.
• Omics analysis reveals galectin-3 to be a potential key regulator of allergic inflammation in hereditary angioedema.
  Mahajan, The journal of allergy and clinical immunology. Global 2025
  • “...PLF4_HUMAN Platelet factor 4 C47H82N12O14 P02776 Protein 4.153 a .003196 F174A_HUMAN Membrane protein FAM174A C35H60N12O12 Q8TBP5 Protein 3.987 a .004024 TG 54.6 TG 16.0_18.2_20.4 C57H98O6 Lipid 3.946 a .004259 LYAG_HUMAN Lysosomal -glucosidase C114H182N38O40 P10253 Protein 3.916 b .004446 IBP4_HUMAN Insulin-like growth factorbinding protein 4 C54H94N14O16 P22692...”
• A Prevalence of Imprinted Genes within the Total Transcriptomes of Human Tissues and Cells
  Anisimov, Molecular biology international 2012
  • “...with thrombospondin type 1 motif, 16 FLJ16731, ADAMTS16s 5p15.32 Candidate Maternal TACCCCTGAA * AK122980 38 Q8TBP5 Family with sequence similarity 174, member A FAM174A 5q21.1 Candidate Paternal ACCCAGCGGG * NM_198507 39 CSF2 Colony-stimulating factor 2 (granulocyte-macrophage) GMCSF, MGC131935, MGC138897 5q23.3 Candidate Maternal GTGGGAGTGG BC108724 40 BTNL2...”

F174B_HUMAN / Q3ZCQ3 Membrane protein FAM174B from Homo sapiens (Human) (see paper)
Aligns to 6:159 / 159 (96.9%), covers 92.8% of PF06679, 141.2 bits

• function: Essential for Golgi structural integrity.

NP_060384 protein FAM174C precursor from Homo sapiens
Aligns to 63:132 / 132 (53.0%), covers 38.9% of PF06679, 43.1 bits

• A novel recently evolved gene C19orf24 encodes a non-classical secreted protein.
  Wang, Cellular & molecular biology letters 2006
  • GeneRIF: The isolation and characterization of a novel human non-classical secreted protein which is encoded by the hypothetical gene C19orf24 (chromosome 19 open reading frame 24), is reported.

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