Family Search for PF06749 (DUF1218)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF06749 hits 15 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
AT4G27435 fiber (DUF1218) from Arabidopsis thaliana
Aligns to 58:153 / 173 (55.5%), covers 98.9% of PF06749, 109.9 bits
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective
Lv, International journal of molecular sciences 2023 - “...61 , 62 ]. Moreover, previous findings have studied the expression of two genes, viz., At4g27435 (DUF1218-encoding gene) and the CesA gene, and found that the cellulose content of the mutant remained unchanged compared to the control [ 62 , 63 ]. Additionally, another DUF1218-encoding gene...”
- TRANVIA (TVA) facilitates cellulose synthase trafficking and delivery to the plasma membrane
Vellosillo, Proceedings of the National Academy of Sciences of the United States of America 2021 (secret) - Candidate Domestication-Related Genes Revealed by Expression Quantitative Trait Loci Mapping of Narrow-Leafed Lupin (Lupinus angustifolius L.)
Plewiński, International journal of molecular sciences 2019 - “...group of DUF1218 genes has been related to secondary cell wall biosynthesis and includes AtUNKA (At4g27435), MODIFYING WALL LIGNIN-1, and MODIFYING WALL LIGNIN-2 (At1g31720/MWL-1 and At4g19370/MWL-2) [ 86 , 87 , 88 ]. Lup018348 encodes a homolog of DETOXIFICATION14 , a member of the multidrug and...”
- Temporal analysis of Arabidopsis genes activated by Eucalyptus grandis NAC transcription factors associated with xylem fibre and vessel development
Laubscher, Scientific reports 2018 - “...348.2 AT1G33800 Glucuronoxylan(GX)-specific 4-O-methyltransferase 97.3 167.6 1165.0 AT1G31720 MODIFYING WALL LIGNIN 1 (MWL1) Inf* Inf* AT4G27435 MODIFYING WALL LIGNIN 2 (MWL2) 68.3 1626.9 AT5G18460 Protein of Unknown Function (DUF239) 242.1 295.1 651.0 453.4 AT4G09990 Protein of Unknown Function (DUF579) 8.6 8.1 113.8 AT4G18425 Protein of Unknown...”
- Transgenic expression of fungal accessory hemicellulases in Arabidopsis thaliana triggers transcriptional patterns related to biotic stress and defense response
Tsai, PloS one 2017 - “...protease family protein AT5G60020 1.053 0.002 -0.235 0.667 0.423 0.404 LAC17 laccase activity, lignin biosynthesis AT4G27435 1.467 0.000 -0.311 0.394 0.593 0.062 DUF1218 AT5G60720 0.785 0.022 -0.129 0.824 0.392 0.414 DUF547 AT1G32100 0.775 0.000 -0.172 0.588 0.343 0.222 PRR1 pinoresinol reductase, lignan biosynthesis AT4G33330 1.156 0.001...”
- The Arabidopsis Domain of Unknown Function 1218 (DUF1218) Containing Proteins, MODIFYING WALL LIGNIN-1 and 2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content
Mewalal, PloS one 2016 - “...and abiotic/biotic stress response. The Arabidopsis genome encodes 15 members, two of which (At1g31720 and At4g27435) are preferentially expressed in the secondary cell wall depositing inflorescence stems. To further our understanding of the roles of DUF1218-containing proteins in secondary cell wall biology, we functionally characterized At1g31720...”
- “...]. Independent studies [ 4 , 9 ] reported expression correlation between a DUF1218-encoding gene (At4g27435) and the secondary cell wall-related cellulose synthase (CesA) genes. The cellulose content of a loss-of-function mutant line for At4g27435 remained unchanged relative to the WT control plants [ 4 ,...”
- Identification of novel transcription factors regulating secondary cell wall formation in Arabidopsis
Cassan-Wang, Frontiers in plant science 2013 - “...Protein of unknown function, DUF547 * 249439_at AT5G40020 0.68 Pathogenesis-related thaumatin superfamily protein * 253877_at AT4G27435 0.68 Protein of unknown function (DUF1218) * 253710_at AT4G29230 NAC075 0.68 NAC domain containing protein 75 * Annotated involved in xylan biosynthetic process and/or cell wall biogenesis and/or cell wall...”
- SND2, a NAC transcription factor gene, regulates genes involved in secondary cell wall development in Arabidopsis fibres and increases fibre cell area in Eucalyptus
Hussey, BMC plant biology 2011 - “...1) 1.35 2.04E-03 Unknown function AT3G22540 Unknown protein 1.58 1.50E-06 AT1G33800 Unknown protein 1.55 4.24E-06 AT4G27435 Unknown protein 1.43 5.42E-04 AT5G64190 Unknown protein 1.42 6.86E-04 AT5G61340 Unknown protein 1.39 1.63E-03 AT1G07120 Unknown protein 1.32 1.47E-02 AT1G03820 Unknown protein 1.32 1.88E-02 AT1G24600 Unknown protein -1.33 1.29E-02 AT5G66170...”
- “...Unknown protein AT2G31930 0.936 Unknown protein CesA4 (AT5G44030) 0.934 Secondary cell wall cellulose synthase protein AT4G27435 0.934 Protein of unknown function (DUF1218) AT1G22480 0.933 Cupredoxin superfamily protein IRX10 (AT1G27440) 0.929 Glucuronoxylan glucuronosyltransferase CesA8 (AT4G18780) 0.926 Secondary cell wall cellulose synthase protein RWA3 (AT2G34410) 0.915 Polysaccharide O-acetyltransferase...”
- More
Q6T7D3 Fiber protein Fb34 from Gossypium barbadense
Aligns to 58:153 / 185 (51.9%), covers 98.9% of PF06749, 108.6 bits
AT1G52910 hypothetical protein from Arabidopsis thaliana
Aligns to 58:154 / 175 (55.4%), covers 100.0% of PF06749, 106.7 bits
AT3G15480 hypothetical protein from Arabidopsis thaliana
Aligns to 58:154 / 175 (55.4%), covers 100.0% of PF06749, 106.2 bits
- TRANVIA (TVA) facilitates cellulose synthase trafficking and delivery to the plasma membrane
Vellosillo, Proceedings of the National Academy of Sciences of the United States of America 2021 (secret) - Dissecting plasmodesmata molecular composition by mass spectrometry-based proteomics
Salmon, Frontiers in plant science 2012 - “...suspension cells Formation of specialized membrane microdomains PD, PM Fernandez-Calvino et al., 2011 Hypothetical protein At3g15480 A. thaliana suspension cells PD, PM Fernandez-Calvino et al., 2011 Leucine Rich Repeat Receptor-Like Kinase (LRR RLK) OsO6g47750 OsO2g05960 OsO9g02250 Rice callus suspension cells Signaling PD Jo et al., 2011...”
- Arabidopsis plasmodesmal proteome
Fernandez-Calvino, PloS one 2011 - “...receptor-like kinases At1g56145(A, YFP), At4g21380(D, YFP), At5g24010 (E, RFP), and At5g59700 (F, YFP), hypothetical protein At3g15480 containing a DUF1218 domain (B, YFP) and a tetraspanin At3g45600 (C, YFP). PD localisation (arrowheads) is evident as punctae of fluorescence in the cell wall for images shown in AE....”
- “...kDa LRR RLK PM and PD AT1G73650 34 kDa Hypothetical protein - predicted oxidoreductase PM AT3G15480 19 kDa Hypothetical protein containing a DUF1218 PM and PD AT3G25290 43 kDa Auxin responsive family protein PM and ER AT3G45600 32 kDa membrane protein of unknown function - tetraspanin...”
- GeneCAT--novel webtools that combine BLAST and co-expression analyses
Mutwil, Nucleic acids research 2008 - “...28 protein At1g80170 polygalacturonase, putative At1g75500 nodulin MtN21 family protein At3g45870 integral membrane family protein/nodulin At3g15480 expressed protein At4g27435 expressed protein At1g41830 multicopper oxidase type I family protein At5g03260 laccase, putative At2g38080 laccase, putative At5g01190 similar to laccase At5g05390 laccase, putative At2g29130 laccase, putative At5g60020 laccase,...”
AT5G17210 hypothetical protein from Arabidopsis thaliana
Aligns to 61:155 / 209 (45.5%), covers 98.9% of PF06749, 103.4 bits
AT1G68220 hypothetical protein from Arabidopsis thaliana
Aligns to 59:155 / 201 (48.3%), covers 98.9% of PF06749, 89.1 bits
AT1G13380 hypothetical protein from Arabidopsis thaliana
Aligns to 62:154 / 188 (49.5%), covers 98.9% of PF06749, 88.1 bits
- Spatial dissection of the Arabidopsis thaliana transcriptional response to downy mildew using Fluorescence Activated Cell Sorting
Coker, Frontiers in plant science 2015 - “...AT1G12244 AT3G04850 AT1G11720 ATSS3, SS3 AT3G05730 AT1G16350 AT3G23670 PAKRP1L, KINESIN-12B AT1G12845 AT3G15353 MT3 AT1G21440 AT3G28460 AT1G13380 AT3G19450 ATCAD4, AT1G48620 HON5 AT4G11990 AT1G14690 MAP65-7 AT3G45850 AT1G48650 AT4G21270 ATK1, KATAP AT1G27385 AT3G54190 AT1G54820 AT4G22930 PYR4, DHOASE AT1G35780 AT3G60840 MAP65-4 AT1G58060 AT4G30610 BRS1, SCPL24 AT1G48600 AtPMEAMT AT4G37080 AT1G63630 AT4G34210...”
- Plum (Prunus domestica) trees transformed with poplar FT1 result in altered architecture, dormancy requirement, and continuous flowering
Srinivasan, PloS one 2012 - “...standard single copy gene, 4040, most closely related to an unknown protein in Arabidopsis , AT1G13380 was determined [25] . The lowest ratio was set to one copy and the remaining ratios were divided by that number to determine the relative copy number. Cold-induced Dormancy One...”
NP_001321400 chitin synthase, putative (DUF1218) from Arabidopsis thaliana
Aligns to 67:157 / 184 (49.5%), covers 98.9% of PF06749, 83.0 bits
AT1G31720 hypothetical protein from Arabidopsis thaliana
Aligns to 77:167 / 194 (46.9%), covers 98.9% of PF06749, 79.3 bits
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective
Lv, International journal of molecular sciences 2023 - “...unchanged compared to the control [ 62 , 63 ]. Additionally, another DUF1218-encoding gene ( At1g31720 ) was highly expressed in the Arabidopsis stem and, at the same time, co-expressed in the cell wall cellulose synthase gene along with lignin- and xylan-linked genes. These outcomes showed...”
- “...); DGR2 ( At5g25460 ) DUF642 PF04862 L-Galactono-1,4-Lactone-responsive Genes Arabidopsis [ 33 ] MWL-1 ( At1g31720 ); MWL-2 ( At4g19370 ) DUF1218 PF06749 At1g31720 and At4g19370 function redundantly to alter secondary cell wall lignin content Arabidopsis [ 26 ] Reproductive development LpSDUF247 DUF247 PF03140 Cosegregates with...”
- Candidate Domestication-Related Genes Revealed by Expression Quantitative Trait Loci Mapping of Narrow-Leafed Lupin (Lupinus angustifolius L.)
Plewiński, International journal of molecular sciences 2019 - “...of Unknown Function 1218 ( DUF1218 ) containing proteins, MODIFYING WALL LIGNIN-1 and 2 ( At1g31720 / MWL-1 and At4g19370 / MWL-2 ) function redundantly to alter secondary cell wall lignin content PLoS ONE 2016 11 e0150254 10.1371/journal.pone.0150254 26930070 89. Miyauchi H. Moriyama S. Kusakizako T....”
- Temporal analysis of Arabidopsis genes activated by Eucalyptus grandis NAC transcription factors associated with xylem fibre and vessel development
Laubscher, Scientific reports 2018 - “...AT3G62020 Germin-like protein 10 (GLP10) 4.2 48.1 16.0 348.2 AT1G33800 Glucuronoxylan(GX)-specific 4-O-methyltransferase 97.3 167.6 1165.0 AT1G31720 MODIFYING WALL LIGNIN 1 (MWL1) Inf* Inf* AT4G27435 MODIFYING WALL LIGNIN 2 (MWL2) 68.3 1626.9 AT5G18460 Protein of Unknown Function (DUF239) 242.1 295.1 651.0 453.4 AT4G09990 Protein of Unknown Function...”
- Overexpression and cosuppression of xylem-related genes in an early xylem differentiation stage-specific manner by the AtTED4 promoter
Endo, Plant biotechnology journal 2018 - “...0.499 0.085 3 At3g16920 107.757 7.235 2 At1g79180 0.756 0.409 2 AtTED4 5.402 2.006 0 At1g31720 0.886 0.045 2 UBQ10 100.000 0 At5g01360 0.997 0.089 4 ATHB8 0.305 0.078 17 At5g59305 1.058 0.145 2 TDR/PXY 0.518 0.096 1 John Wiley & Sons, Ltd A survey of...”
- The Arabidopsis Domain of Unknown Function 1218 (DUF1218) Containing Proteins, MODIFYING WALL LIGNIN-1 and 2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content
Mewalal, PloS one 2016 - “...2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content DUF1218 Proteins At1g31720 and At4g19370 Affect Lignin Content Mewalal Ritesh 1 Mizrachi Eshchar 1 Coetzee Berdine 2 3 Mansfield Shawn D. 4 Myburg Alexander A. 1 * 1 Department of Genetics, Forestry and...”
- “...vasculature patterning and abiotic/biotic stress response. The Arabidopsis genome encodes 15 members, two of which (At1g31720 and At4g27435) are preferentially expressed in the secondary cell wall depositing inflorescence stems. To further our understanding of the roles of DUF1218-containing proteins in secondary cell wall biology, we functionally...”
- Transcriptomic and proteomic profiling of maize embryos exposed to camptothecin
Sánchez-Pons, BMC plant biology 2011 - “...Zm.2192.1.A1_at 1.1864 0.0189 0.0000 <0.001 Nd Unknown protein BQ538249 Zm.10551 Zm.10551.1.A1_at 1.0488 0.0438 0.0003 0.002 At1g31720 (6e-23) AAA-type ATPase/ATPase2 CK826796 Zm.94919 Zm.16211.1.S1_at 3.2748 0.0189 0.0000 <0.001 At3g28540 (0.0) GB#, maize EST accession number in GenBank database. UniGene ID code; Probe set ID in Affymetrix chip; Affymetrix...”
DEAL2_ARATH / O81898 Protein DESIGUAL 2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
AT4G21310 hypothetical protein from Arabidopsis thaliana
Aligns to 58:146 / 168 (53.0%), covers 98.9% of PF06749, 78.8 bits
- function: Involved, partially redundantly with VCC/DEAL1 and DEAL3, to ensure bilateral symmetry development and early leaf margin patterning, probably via the regulation of auxin and CUC2 distribution.
disruption phenotype: Developmental defects of pistils, some being bent or coiled or twisted, and some showing unfused carpels with exposed ovules (PubMed:29139551). The vcc-3 deal2-1 double mutant shows leaf asymmetry (PubMed:29139551). The vcc-3 deal2-1 deal3-1 triple mutant shows a strong leaf asymmetry (PubMed:29139551). - Long-Term Balancing Selection and the Genetic Load Linked to the Self-Incompatibility Locus in Arabidopsis halleri and A. lyrata
Le, Molecular biology and evolution 2023 - “...AT4G21340 and AT4G21330 ), one a peptidase ( AT4G21323 ), one a transmembrane protein ( AT4G21310 ), one a tetratricopeptide repeat (TPR)-like superfamily protein ( AT4G21300 ), and the last one is a subunit of photosystem II ( AT4G21280 ). Moreover, some individual genes further away...”
- The Arabidopsis Domain of Unknown Function 1218 (DUF1218) Containing Proteins, MODIFYING WALL LIGNIN-1 and 2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content
Mewalal, PloS one 2016 - “...targeted to the cell periphery (plasma membrane or extracellular). Furthermore, all proteins (except At1g52910 and At4g21310) contained a predicted signal peptide and varied in their transmembrane topology ( S1A Fig ). Full-length MWL-1 and MWL-2 proteins have approximately 34 and 58% amino acid identity and similarity...”
DEAL1_ARATH / Q9ZV57 Protein VASCULATURE COMPLEXITY AND CONNECTIVITY; Protein DESIGUAL 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
AT2G32280 hypothetical protein from Arabidopsis thaliana
Aligns to 58:146 / 163 (54.6%), covers 100.0% of PF06749, 76.4 bits
- function: Required, together with OPS, for embryo provasculature development and cotyledon vascular complexity and connectivity (PubMed:25149602). Necessary, partially redundantly with DEAL2 and DEAL3, to ensure bilateral symmetry development and early leaf margin patterning, probably via the regulation of auxin and CUC2 distribution (PubMed:29139551). Regulates cell proliferation but not cell expansion (PubMed:29139551).
subunit: Interacts with OPS.
disruption phenotype: Defects in vein connectivity early in mutant embryo development leading to reduced complexity of cotyledon vein networks and disconnected veins, including in embryos provasculatures (PubMed:25149602). The mutant deal1-1 exhibits a bilateral symmetry breaking but no obvious defects in dorsoventrality; early leaf primordia fail to acquire bilateral symmetry and instead form ectopic lobes and sinuses (PubMed:29139551). Developmental defects of pistils, some being bent or coiled or twisted, and some showing unfused carpels with exposed ovules (PubMed:29139551). In leaves, marginal cells expressing properly polarized PIN1 are badly recruited, thus leading to misplaced auxin maxima, as well as defects in cell proliferation but not in cell expansion (PubMed:29139551). Altered spatial pattern of CUC2 (PubMed:29139551). The double mutant vcc ops exhibits a complete loss of high-complexity vascular networks (PubMed:25149602). The vcc-3 deal2-1 and vcc-3 deal3-1 double mutants show leaf asymmetry (PubMed:29139551). The vcc-3 deal2-1 deal3-1 triple mutant shows a strong leaf asymmetry (PubMed:29139551). - Ticarcillin degradation product thiophene acetic acid is a novel auxin analog that promotes organogenesis in tomato
George, Frontiers in plant science 2023 - “...in our data and shows maximum similarity to Arabidopsis gene VASCULATURE COMPLEXITY AND CONNECTIVITY (VCC, AT2G32280). Expression of VCC in Arabidopsis is upregulated by auxin and the gene is reported to control the development of veins in cotyledons. VCC plays a role in the localization and...”
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective
Lv, International journal of molecular sciences 2023 - “...DUF266-containing protein is implicated in rice leaf senescence Oryza sativa [ 44 ] VCC ( At2g32280 ) DUF1218 PF06749 VCC is required for bilateral symmetry, but its loss of function does not visibly affect dorsoventrality Arabidopsis [ 45 ] ijms-24-04187-t002_Table 2 Table 2 The role of...”
- Weighted Gene Correlation Network Analysis (WGCNA) of Arabidopsis Somatic Embryogenesis (SE) and Identification of Key Gene Modules to Uncover SE-Associated Hub Genes
de, International journal of genomics 2022 - “...PROTEIN2 (AT4G30850), INDOLE-3-ACETIC ACID INDUCIBLE 30 ( IAA30 /AT3G62100), RPS9C , VASCULATURE COMPLEXITY AND CONNECTIVITY (AT2G32280), AT2G21820 , AT2G38900 , and AT5G43770 showed a marked expression in somatic embryonic tissues as compared to leaf tissues. Expression analysis using the Arabidopsis eFP browser further showed that AT2G29300...”
- Callus, Dedifferentiation, Totipotency, Somatic Embryogenesis: What These Terms Mean in the Era of Molecular Plant Biology?
Fehér, Frontiers in plant science 2019 - “...factor B3 family protein/auxin-responsive factor AT1G33790 AT1G33790 Jacalin lectin family protein AT1G55610 BRL1 BRI1 like AT2G32280 AT2G32280 GPI inositol-deacylase C, putative (DUF1218) AT2G39350 ABCG1 ABC-2 type transporter family protein AT2G43510 TI1 Trypsin inhibitor protein 1 AT2G47260 WRKY23 WRKY DNA-binding protein 23 AT3G01970 WRKY45 WRKY DNA-binding protein...”
- Global DNA methylation variations after short-term heat shock treatment in cultured microspores of Brassica napus cv. Topas
Li, Scientific reports 2016 - “...+ NA NA 35.27 BnaA03g39020D 377 + AT2G16365 F-box family protein 46.27 BnaA05g10770D 626 + AT2G32280 vasculature complexity and connectivity (VCC) 26.27 BnaA05g16350D 1480 + AT1G32180 cellulose synthase-like d6 (CSLD6) 28.30 BnaA07g12210D 1222 AT5G66985 unknown protein 40.63 BnaA09g20620D 342 AT4G04020 plastoglobulin 35 (PGL35) 29.73 BnaC01g08880D 0...”
- Expression profiling of tomato pre-abscission pedicels provides insights into abscission zone properties including competence to respond to abscission signals
Nakano, BMC plant biology 2013 - “...0.003 Solyc09g008740 A_96_P160421 AW625490 AT2G22880 VQ motif-containing protein 2.8 0.012 2.1 0.022 Solyc12g005700 A_96_P016566 BT012940 AT2G32280 unknown protein 2.4 0.011 5.4 0.004 Solyc10g007310 A_96_P084909 BW687670 AT2G42610 LSH10 (LIGHT SENSITIVE HYPOCOTYLS 10) 2.3 0.017 3.6 0.002 Solyc03g114130 A_96_P219824 AK329003 AT3G01430 unknown 1.8 0.002 1.9 0.003 Solyc01g081270 A_96_P152326...”
MWL1_ARATH / A2RVU1 Protein MODIFYING WALL LIGNIN-1; MWL-1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 58:148 / 175 (52.0%), covers 98.9% of PF06749, 74.5 bits
- function: Together with MWL2, contributes to secondary cell wall biology, specifically lignin biosynthesis.
subunit: Interacts with CRK19.
disruption phenotype: No visible phenotype. Double mutants lacking both MWL1 and MWL2 exhibit smaller rosettes with a decrease in rosette fresh weight and stem height associated with a reduction in total lignin content and an increase in syringyl/guaiacyl (S/G) monomer ratio.
DEAL3_ARATH / A2RVQ4 Protein DESIGUAL 3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 65:153 / 184 (48.4%), covers 98.9% of PF06749, 68.8 bits
- function: Involved, partially redundantly with VCC/DEAL1 and DEAL2, to ensure bilateral symmetry development and early leaf margin patterning, probably via the regulation of auxin and CUC2 distribution.
disruption phenotype: No visible phenotype (PubMed:29139551). The vcc-3 deal3-1 double mutant shows leaf asymmetry (PubMed:29139551). The vcc-3 deal2-1 deal3-1 triple mutant shows a strong leaf asymmetry (PubMed:29139551).
MWL2_ARATH / O65708 Protein MODIFYING WALL LIGNIN-2; MWL-2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
NP_193672 chitin synthase, putative (DUF1218) from Arabidopsis thaliana
AT4G19370 hypothetical protein from Arabidopsis thaliana
Aligns to 55:151 / 217 (44.7%), covers 96.8% of PF06749, 66.7 bits
- function: Together with MWL1, contributes to secondary cell wall biology, specifically lignin biosynthesis.
disruption phenotype: No visible phenotype. Double mutants lacking both MWL1 and MWL2 exhibit smaller rosettes with a decrease in rosette fresh weight and stem height associated with a reduction in total lignin content and an increase in syringyl/guaiacyl (S/G) monomer ratio. - The Arabidopsis Domain of Unknown Function 1218 (DUF1218) Containing Proteins, MODIFYING WALL LIGNIN-1 and 2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content.
Mewalal, PloS one 2016 - GeneRIF: Studies functionally characterized At1g31720 and At4g19370 (MODIFYING WALL LIGNIN-1/2 or MWL-1/2) for secondary cell wall lignin biosynthesis.
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective
Lv, International journal of molecular sciences 2023 - “...) DUF642 PF04862 L-Galactono-1,4-Lactone-responsive Genes Arabidopsis [ 33 ] MWL-1 ( At1g31720 ); MWL-2 ( At4g19370 ) DUF1218 PF06749 At1g31720 and At4g19370 function redundantly to alter secondary cell wall lignin content Arabidopsis [ 26 ] Reproductive development LpSDUF247 DUF247 PF03140 Cosegregates with the S self-incompatibility locus...”
- Black sheep, dark horses, and colorful dogs: a review on the current state of the Gene Ontology with respect to iron homeostasis in Arabidopsis thaliana
Mai, Frontiers in plant science 2023 - “...At3g50740 UGT72E1 At3g51200 SAUR18 At3g53280 CYP71B5 At3g58810 MTP3/MTPa2 At3g61930 hypothetical protein At4g02330 PME41 At4g09110 ATL35 At4g19370 MWL-2 At4g30120 HMA3 At5g02780 GSTL1 At5g38820 putative amino acid transporter FIT-regulated according to Mai etal. (2016) ( Mai etal., 2016a ) that are not mentioned above At1g09560 GLP5 At1g11080 scpl31...”
- Candidate Domestication-Related Genes Revealed by Expression Quantitative Trait Loci Mapping of Narrow-Leafed Lupin (Lupinus angustifolius L.)
Plewiński, International journal of molecular sciences 2019 - “...( DUF1218 ) containing proteins, MODIFYING WALL LIGNIN-1 and 2 ( At1g31720 / MWL-1 and At4g19370 / MWL-2 ) function redundantly to alter secondary cell wall lignin content PLoS ONE 2016 11 e0150254 10.1371/journal.pone.0150254 26930070 89. Miyauchi H. Moriyama S. Kusakizako T. Kumazaki K. Nakane T....”
- The Arabidopsis Domain of Unknown Function 1218 (DUF1218) Containing Proteins, MODIFYING WALL LIGNIN-1 and 2 (At1g31720/MWL-1 and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content
Mewalal, PloS one 2016 - “...and At4g19370/MWL-2) Function Redundantly to Alter Secondary Cell Wall Lignin Content DUF1218 Proteins At1g31720 and At4g19370 Affect Lignin Content Mewalal Ritesh 1 Mizrachi Eshchar 1 Coetzee Berdine 2 3 Mansfield Shawn D. 4 Myburg Alexander A. 1 * 1 Department of Genetics, Forestry and Agricultural Biotechnology...”
- “...MWL-1 ). Since related gene family members may contribute to functional redundancy, we also characterized At4g19370 ( MWL-2 ), the most closely related gene to MWL-1 in the protein family. Subcellular localization revealed that both Arabidopsis proteins are targeted to the cell periphery. The single T-DNA...”
- The histone deacetylase HDA19 controls root cell elongation and modulates a subset of phosphate starvation responses in Arabidopsis
Chen, Scientific reports 2015 - “...( IGMT2 , GSTL1 , At3g01260, NMT3 , SKOR , GSTF3 , At5g22555, At2g43590, At4g01430, At4g19370 and FRD3 ) were previously defined as Fe-responsive 29 , while only one such gene ( NAS2 ) was among the genes that showed lower expression in the HDA19-RNAi line....”
DEAL4_ARATH / O23040 Protein DESIGUAL 4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
AT1G05291 hypothetical protein from Arabidopsis thaliana
Aligns to 66:156 / 204 (44.6%), covers 100.0% of PF06749, 43.4 bits
Or search for genetic data about PF06749 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory