Family Search for PF06853 (DUF1249)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF06853 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

CIA_05698 DUF1249 domain-containing protein from Pseudomonas aeruginosa PA14
Aligns to 27:145 / 152 (78.3%), covers 100.0% of PF06853, 149.5 bits

• Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress
  Song, PLoS pathogens 2024
  • “...CIA_05554 esterase EstA -1.09764 0.047568 PA5035 CIA_05632 Glutamate synthase small chain GltD -1.05859 0.002013 PA4970 CIA_05698 hypothetical protein -1.33675 0.000776 PA4916 CIA_05754 NUDIX hydrolase NrtR -1.8394 0.00094 PA4906 CIA_05764 GntR family transcriptional regulator -1.18633 0.009715 PA4841 CIA_05831 NUDIX hydrolase -2.64446 0.006042 PA4839 CIA_05833 Biosynthetic arginine decarboxylase...”

PA4970 hypothetical protein from Pseudomonas aeruginosa PAO1
Aligns to 27:145 / 152 (78.3%), covers 100.0% of PF06853, 149.5 bits

• Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress
  Song, PLoS pathogens 2024
  • “...PA5112 CIA_05554 esterase EstA -1.09764 0.047568 PA5035 CIA_05632 Glutamate synthase small chain GltD -1.05859 0.002013 PA4970 CIA_05698 hypothetical protein -1.33675 0.000776 PA4916 CIA_05754 NUDIX hydrolase NrtR -1.8394 0.00094 PA4906 CIA_05764 GntR family transcriptional regulator -1.18633 0.009715 PA4841 CIA_05831 NUDIX hydrolase -2.64446 0.006042 PA4839 CIA_05833 Biosynthetic arginine...”
• The Pseudomonas aeruginosa RpoH (σ³²) Regulon and Its Role in Essential Cellular Functions, Starvation Survival, and Antibiotic Tolerance
  Williamson, International journal of molecular sciences 2023
  • “...RpoH levels include PA3272, an ATP-dependent helicase, PA4971, an NTP pyrophosphohydrolase, and its adjacent genes, PA4970 (which appears to have a novel protein fold) and PA4969/ cpdA , a 3,5-cyclic-AMP phosphodiesterase. The PA3011/ topA topoisomerase and the adjacent nucleotide binding protein PA3010 are also induced by...”
  • “...RNA binding 2.1 3.4 10 3 PA4969 cpdA 3,5-cyclic-AMP phosphodiesterase 8.6 3.7 10 4 +++ PA4970 Conserved hypothetical protein 7.0 1.4 10 3 PA4971 aspP NTP pyrophosphohydrolase 11.9 6.1 10 4 1 Bold letters show overlap between genes found here and genes induced in P. aeruginosa...”
• A cross-genomic approach for systematic mapping of phenotypic traits to genes
  Jim, Genome research 2004
  • “...PA0623 PA1376 PA5043 PA5040 PA0289 PA1009 PA1661 PA4476 PA4970 PA5225 PA0461 PA0834 PA0612 PA0628 PA4879 PA2017 PA3209 PA5536 PA0080 PA0502 PA1727 PA3726 PA4605...”

YzzH / b3033 DUF1249 domain-containing protein YqiB from Escherichia coli K-12 substr. MG1655 (see paper)
BAA03988.1 ORF2 from Escherichia coli (see paper)
b3033 predicted dehydrogenase from Escherichia coli str. K-12 substr. MG1655
c3779 Hypothetical protein yqiB from Escherichia coli CFT073
Aligns to 21:135 / 140 (82.1%), covers 99.1% of PF06853, 142.1 bits

• The gut microbiota correlate with the disease characteristics and immune status of patients with untreated diffuse large B-cell lymphoma
  Lin, Frontiers in immunology 2023
  • “...proteins were specific to c_Gammaproteobacteria or o_Enterobacteriales , while four including b0354, b1132, b1179, and b3033 were present only in c_Gammaproteobacteria. The functions of these specific proteins may help explain the common physiological or biochemical characteristics of these bacteria and future studies may use the molecular...”
• Identification of in vivo-induced antigens including an RTX family exoprotein required for uropathogenic Escherichia coli virulence
  Vigil, Infection and immunity 2011
  • “...c0445 c1590/3154 c2344 c5347-c5348 c3664 c2954 c2770 c4743 c3779 c3293-c3291 c0446 c5470 c0498 c5419 c2381 c4480 c1511 Function of gene product Respiratory...”

ECA0332 DUF1249 family protein from Pectobacterium atrosepticum SCRI1043
Aligns to 21:135 / 143 (80.4%), covers 99.1% of PF06853, 141.0 bits

• Discovery and profiling of small RNAs responsive to stress conditions in the plant pathogen Pectobacterium atrosepticum
  Kwenda, BMC genomics 2016
  • “...metR, rpoD16 reg_seq13 aldA 139913 140154 242 136.8 30.4 Independent 1 140046 140063 140078 reg_seq27 ECA0332 380584 380826 243 1660.5 389.3 Independent 1 380610 380631 380646 metJ reg_seq31 ECA0449 515673 515910 238 363.3 528.7 Co-expression 1 515790 515813 515828 glpR, ihf, argR2, nagC, argR2, fnr, fis...”
  • “...spot42 sRNA 28756 28882 127 reg_seq13 3 UTR: aldA 139913 140154 242 reg_seq27 3 UTR: ECA0332 TPP riboswitch 380584 380826 243 reg_seq27b 5 UTR: icc isrH (Hfq binding sRNA) 380825 380917 93 reg_seq31 3 UTR: ECA0449 515673 515910 238 reg_seq34 3 UTR: topB STAXI sRNA 601635...”

STM3184 putative cytoplasmic protein from Salmonella typhimurium LT2
Aligns to 21:135 / 140 (82.1%), covers 99.1% of PF06853, 140.6 bits

• Development and application of MLVA methods as a tool for inter-laboratory surveillance
  Nadon, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2013
  • “...] Chiou [ 18 ] PulseNet US [ 17 ] STM2730 STTR6 2730867 ST19 ST5 STM3184 STTR5 3184543 ST25 ST6 STM3246 STTR9 NA ST26 ST7 STM3629 STTR3 3629542 ST06 ST8 pSLT53 STTR10 NA ST40 STTR10 MLVA: multiple-locus variable-number of tandem-repeats analysis; NA: not applicable; VNTR: variable-number...”

NJ56_08730 DUF1249 family protein from Yersinia ruckeri
Aligns to 22:136 / 141 (81.6%), covers 98.3% of PF06853, 139.7 bits

• Genome Sequence of the Fish Pathogen Yersinia ruckeri SC09 Provides Insights into Niche Adaptation and Pathogenic Mechanism
  Liu, International journal of molecular sciences 2016
  • “...Heat shock protein GrpE NJ56_01800 groES Co-chaperonin GroES (HSP10) NJ56_01805 groEL Chaperonin GroEL (HSP60 family) NJ56_08730 hslJ Heat shock protein HslJ NJ56_16480 hchA Chaperone protein HscA NJ56_16250 yegD Hypothetical chaperone protein NJ56_13065 hslO Molecular chaperone Hsp33 NJ56_03020 dnaK Molecular chaperone DnaK NJ56_03025 dnaJ Molecular chaperone DnaJ...”

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