Family Search for PF06998 (DUF1307)
Running HMMer for PF06998
PF06998 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
lmo0207 hypothetical lipoprotein from Listeria monocytogenes EGD-e
Aligns to 28:149 / 153 (79.7%), covers 100.0% of PF06998, 162.2 bits
- Rli51 Attenuates Transcription of the <i>Listeria</i> Pathogenicity Island 1 Gene <i>mpl</i> and Functions as a <i>Trans</i>-Acting sRNA in Intracellular Bacteria
Morón, International journal of molecular sciences 2024 - “...genes in intracellular rli51 ( rli38 , lmo2186, and lmo0937 ), and for the upregulated lmo0207 ( orfZ ). In addition, the predicted binding sites in Rli51 for these targets lay in critical ssRNA loops L1, L2, or both ( Figure 4 B; Supplementary Table S5...”
- “...genes belonging to LIPI-1: hly, mpl, actA, plcB , orfX, and orfZ (see lmo0202 to lmo0207 in Supplementary Table S2 ). mpl, actA, and plcB belong to the lecithinase operon and can be transcribed from the rli51 promoter as a single mRNA [ 14 ]. Consistently,...”
- Listeriomics: an Interactive Web Platform for Systems Biology of Listeria
Bécavin, mSystems 2017 - “...blue circles). Exp, exponential. (B) Coexpression network of the virulence locus genes ( lmo0200 to lmo0207 ) of L.monocytogenes EGD-e. Network nodes are genome elements (genes and noncoding RNAs) with the same color code as in the genome viewer tool. (C) Circular graph visualization of the...”
- SpoVG Is a Conserved RNA-Binding Protein That Regulates Listeria monocytogenes Lysozyme Resistance, Virulence, and Swarming Motility
Burke, mBio 2016 - “...lmo0196 and lmo0197 ) occupy the locus adjacent to the PrfA regulon ( lmo0200 to lmo0207 ), which although possibly coincidental may suggest coregulation. Indeed, both genes are modestly regulated by SigB ( 44 ) and by PTS-dependent sugar abundance ( 45 ). We suggest that,...”
- A detailed view of the intracellular transcriptome of Listeria monocytogenes in murine macrophages using RNA-seq
Schultze, Frontiers in microbiology 2015 - “...inducing protein precursor Up lmo1786 inlC Internalin C Up lmo0202 hly Listeriolysin O precursor Up lmo0207 lmo0207 Hypothetical protein Up lmo0838 hpt Sugar:phosphate antiporter Up lmo0608 lmo0608 ABC transporter ATP-binding protein Up lmo2828 lmo2828 Hypothetical protein Up lmo0206 lmo0206 Hypothetical protein Up lmo0751 lmo0751 Hypothetical protein...”
- “...in all studies. In addition to the virulence cluster, PrfA-regulated expression has been reported for lmo0207 ( orfZ ), lmo0796 , lmo0434 ( inlB ), lmo1786 ( inlC ), lmo2219 ( prsA2 ), and lmo0838 ( hpt ). lmo0207 and lmo0206 , which were significantly upregulated...”
- Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
Hain, BMC genomics 2012 - “...the latter half of the cluster, with differences most prominently visible in the regions containing lmo0207 and lmo0209 . lmo0207 encodes a lipoprotein and was identified as one of the most divergent genes of the LIPI-1 when comparing three lineages. Figure 2 Alignment of the virulence...”
- “...confer a severe growth effect on survival in macrophages, [ 20 ] while loss of lmo0207 has a small effect on growth in macrophages and no data are presently available for lmo0208 and lmo0209 and their role in virulence. Differential regulation of intracellular flagella gene expression...”
- In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection
Camejo, PLoS pathogens 2009 - “...protein inlH known to be involved in Listeria virulence [24] . Two genes, lmo0206 and lmo0207 , recently shown as regulated by PrfA and implicated in L. monocytogenes intracellular survival [14] were also activated in infected mice. Importantly, no gene previously shown under the PrfA positive...”
- “...lmo0937 lmo0937 unknown protein lin0936 3,92 Other PrfA regulated genes lmo0206 lmo0206 unknown protein 3,11 lmo0207 lmo0207 hypothetical lipoprotein lin0239 5,31 3,27 VirR, another key Listeria virulence regulator that mainly controls genes involved in the modification of bacterial surface components, is the response regulator of a...”
- Listeria monocytogenes sigmaB modulates PrfA-mediated virulence factor expression
Ollinger, Infection and immunity 2009 - “...levels. Five of these genes (i.e., hly, actA, plcB, lmo0207, and lmo2684) had higher transcript levels in the presence of PrfA* and lower transcript levels in...”
- “...University of California, Berkeley hly actAe plcA plcB lmo0207 lmo2219 lmo2684 inlAe mpl inlB inlC lmo0090 lmo0443 lmo0484e lmo2261 QTCc qRT-PCR result (fold...”
- Biotechnological applications of Listeria's sophisticated infection strategies
Barbuddhe, Microbial biotechnology 2008 - “...the regulation of the PrfA transcriptional activator protein. These include lmo0206 ( orfX ) and lmo0207 ( orfZ ), encoding gene products of unknown function as well as prsA which encodes a product homologous to the posttranslocation molecular chaperone protein PrsA of Bacillus subtilis ( Chatterjee...”
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lin0239 hypothetical lipoprotein from Listeria innocua Clip11262
Aligns to 28:149 / 153 (79.7%), covers 100.0% of PF06998, 156.5 bits
- In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection
Camejo, PLoS pathogens 2009 - “...lin0936 3,92 Other PrfA regulated genes lmo0206 lmo0206 unknown protein 3,11 lmo0207 lmo0207 hypothetical lipoprotein lin0239 5,31 3,27 VirR, another key Listeria virulence regulator that mainly controls genes involved in the modification of bacterial surface components, is the response regulator of a two-component system (TCS) implicated...”
- “...to a probable high-affinity zinc ABC transporter (Zn(II)-binding lipoprotein) lin0191 5,31 lmo0207 lmo0207 hypothetical lipoprotein lin0239 5,31 3,27 lmo0303 lmo0303 putaive secreted, lysin rich protein lin0331 3,18 lmo0355 lmo0355 similar to Flavocytochrome C Fumarate Reductase chain A lin0374 2,97 6,68 2,51 lmo0366 lmo0366 putative lipoprotein lin0385...”
YehR / b2123 DUF1307 domain-containing lipoprotein YehR from Escherichia coli K-12 substr. MG1655 (see 2 papers)
b2123 orf, hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 28:150 / 153 (80.4%), covers 100.0% of PF06998, 152.0 bits
STY2386 putative lipoprotein from Salmonella enterica subsp. enterica serovar Typhi str. CT18
t0699 putative lipoprotein from Salmonella enterica subsp. enterica serovar Typhi Ty2
Aligns to 52:173 / 176 (69.3%), covers 100.0% of PF06998, 144.8 bits
- Salmonella chronic carriage: epidemiology, diagnosis, and gallbladder persistence
Gunn, Trends in microbiology 2014 - “...SPI-1 and SPI-2 genes ( Salmonella pathogenicity islands); transcription regulator; cytoplasmic protein [ 71 ] STY2386 Putative lipoprotein [ 72 ] pduG (STY2248) pduG (STM2043) Propanediol degradation; pdu operon co-regulated with cob operon appears to encode for cobalamin adenosyl transferase activity [ 73 ] STY2386 STM2156A...”
- Identification of immunogenic Salmonella enterica serotype Typhi antigens expressed in chronic biliary carriers of S. Typhi in Kathmandu, Nepal
Charles, PLoS neglected tropical diseases 2013 - “...periplasmic protein STY1479 yncE Possible ATP-binding protein STY2155 sirA Invasion response-regulator STY2248 pduG PduG protein STY2386 Putative lipoprotein STY2454 yejE Putative binding-protein-dependent transporter STY2657 xapB Xanthosine permease STY3709 purH Phosphoribosylaminoimidazolecarboxamideformyltransferase and IMP cyclohydrolase (bifunctional enzyme) HCM1.137 repE Replication initiation protein HCM1.213c Putative transposase HCM2.0043 Hypothetical protein...”
- “...the genes identified by IVIAT encode for proteins with putative or unknown function. For example, STY2386 is an uncharacterized lipoprotein found uniquely in Salmonella . STY1364 is a hypothetical periplasmic protein in S. Typhi and S. Paratyphi A, and is rarely found in other Salmonella spp....”
- Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium
Wong, PloS one 2013 - “...yehX, yehW, yehU, yehT and yehS are located on the forward strand, whilst t0694, yehV, t0699 and yehR lie on the reverse strand ( Figure 1 ) [ 26 , 46 ]. The function of these genes is not currently known, although our sequence comparison-using Interpro...”
- “...genes include yehV , t0694 , yehW , yehX (upstream of yehU ) and yehS, t0699 and yehR (downstream from yehT ). B The domain organisation of the YehU and YehT proteins . YehU protein comprises of five transmembrane (TM) alpha helical segments predicted using TMHMM...”
STM2156A hypothetical 16.9 kd lipoprotein precursor from Salmonella typhimurium LT2
Aligns to 52:173 / 176 (69.3%), covers 100.0% of PF06998, 144.0 bits
- Salmonella chronic carriage: epidemiology, diagnosis, and gallbladder persistence
Gunn, Trends in microbiology 2014 - “...with cob operon appears to encode for cobalamin adenosyl transferase activity [ 73 ] STY2386 STM2156A Putative lipoprotein [ 34 ] yejE (STY2454) yejE (STM2218) Confers resistance to antimicrobial peptides and contributes to virulence; ABC-type dipeptide/oligopeptide/nickel transport system permease component; upregulated in macrophages [ 74 ]...”
SAUSA300_2403 putative lipoprotein from Staphylococcus aureus subsp. aureus USA300_FPR3757
Aligns to 25:143 / 151 (78.8%), covers 100.0% of PF06998, 134.6 bits
- Aspartate tightens the anchoring of staphylococcal lipoproteins to the cytoplasmic membrane
Kumari, MicrobiologyOpen 2017 - “...USA300 Detected (Becher etal., 2009 ; Hanzelmann etal., 2016 ; Muthukrishnan etal., 2011 ) 54. SAUSA300_2403 Unknown function C GKEQ No TMD USA300 Detected (Hanzelmann etal., 2016 ) 55. SAUSA300_0724 Unknown function C GNKE No TMD MRSA clinical isolates Detected (Sibbald etal., 2006 ; Herbert, Ziebandt...”
- Evaluation of Staphylococcus aureus Lipoproteins: Role in Nutritional Acquisition and Pathogenicity
Shahmirzadi, Frontiers in microbiology 2016 - “...* 53 SAUSA300_0992 Cell-wall binding lipoprotein YkyA, EzrA 19 LAG C 23 13 * 54 SAUSA300_2403 Unknown function DUF1307 20 LSA C 17 12 * 55 SAUSA300_0724 Unknown function IncA, TarH 19 ISA C 32 12 56 SAUSA300_2315 Unknown function PA26, IncA, CLN3 17 LAA C...”
- Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis
Diep, The Journal of infectious diseases 2014 - “...transporter iron compoundbinding protein 36.74 10 Lipoprotein SAUSA300_2403 SAUSA300_2328 ... ... Putative lipoprotein Hypothetical protein 17.31 13.34 8 7...”
- Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability
Kolar, MicrobiologyOpen 2013 - “...proteases, as expected, along with catalase (ninefold), the CamS pheromone (twofold), and two putative lipoproteins (SAUSA300_2403 = twofold, SAUSA300_0411 = threefold). A consideration with this pooled analysis is that a protein may be processed by secreted proteases into potentially inactive fragments, as a result of endoproteolysis....”
SA2247 hypothetical protein from Staphylococcus aureus subsp. aureus N315
Aligns to 25:143 / 151 (78.8%), covers 100.0% of PF06998, 134.6 bits
SAR2546 putative lipoprotein from Staphylococcus aureus subsp. aureus MRSA252
Aligns to 25:143 / 151 (78.8%), covers 100.0% of PF06998, 134.6 bits
NM219_00920, NM220_00920 YehR family lipoprotein from Parvimonas micra
Aligns to 31:155 / 158 (79.1%), covers 99.2% of PF06998, 114.1 bits
- Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma
Conde-Pérez, Molecular oncology 2024 - “...25 NM219_00080 NM220_00080 DUF1307 domaincontaining protein 486 26 NM219_00915 NM220_00915 DUF1307 domaincontaining protein 477 26 NM219_00920 NM220_00920 DUF2087 domaincontaining protein 270 27 NM219_01675 NM220_01675 GNAT family Nacetyltransferase 480 27 NM219_01680 NM220_01680 ABC transporter permease 1263 28 NM219_06715 NM220_06715 Hypothetical protein 636 29 NM219_03355 NM220_03355 Hypothetical protein...”
- “...NM219_00080 NM220_00080 DUF1307 domaincontaining protein 486 26 NM219_00915 NM220_00915 DUF1307 domaincontaining protein 477 26 NM219_00920 NM220_00920 DUF2087 domaincontaining protein 270 27 NM219_01675 NM220_01675 GNAT family Nacetyltransferase 480 27 NM219_01680 NM220_01680 ABC transporter permease 1263 28 NM219_06715 NM220_06715 Hypothetical protein 636 29 NM219_03355 NM220_03355 Hypothetical protein 372...”
SGO_0004 putative lipoprotein from Streptococcus gordonii str. Challis substr. CH1
Aligns to 30:160 / 172 (76.2%), covers 94.3% of PF06998, 112.8 bits
- Streptococcus gordonii Type I Lipoteichoic Acid Contributes to Surface Protein Biogenesis
Lima, mSphere 2019 - “...SGO_1576 PTS, cellobiose-specific IIC component SGO_1763 Putative aldouronate transport system substrate-binding protein SGO_1799 Putative endopeptidase SGO_0004 Putative lipoprotein SGO_0233 Putative lipoprotein SGO_0060 Putative membrane protein SGO_0140 Putative multi-antimicrobial-extrusion family transporter ArcT SGO_1589 Putative transaminase/peptidase LytR SGO_0535 Putative transcriptional regulator Pyk SGO_1339 Pyruvate kinase SGO_0667 Rhodanese family...”
- Mass Spectrometric Analysis of Whole Secretome and Amylase-precipitated Secretome Proteins from Streptococcus gordonii.
Maddi, Journal of proteomics & bioinformatics 2014 - “...65 3 4.9 L-lactate dehydrogenase ldh SGO_1232 L-lactate dehydrogenase 35 3 9.1 Putative lipoprotein * SGO_0004 Unknown 20 3 17.4 Possible cell wall protein * SGO_0846 SCP-like extracellular protein domain n 76 3 5.2 Glutamine ABC transporter permease and substrate binding protein * SGO_1037 ABC transporter...”
- Proteomics of Streptococcus gordonii within a model developing oral microbial community
Hendrickson, BMC microbiology 2012 - “...11 6 5 4 0 0 Decrease 9 5 10 8 8 5 a Covers SGO_0004, 0068, 0208, 0233, 0388, 0430, 0455, 0494, 0502, 0521, 0707, 0721, 0825, 0890, 1069, 1082, 1110, 1189, 1347, 1355, 1381, 1487, 1651, 1898, 2004, 2005, 2082. b Covers SGO_0054, 0056,...”
lmo0255 similar to unknown protein from Listeria monocytogenes EGD-e
Aligns to 37:163 / 167 (76.0%), covers 100.0% of PF06998, 103.2 bits
- Listeria monocytogenes surface proteins: from genome predictions to function
Bierne, Microbiology and molecular biology reviews : MMBR 2007 - “...of unknown function, the genes for six of which (Lmo0255, Lmo0460, Lmo0617, Lmo1340, Lmo2594, and Lmo2595) are absent from the L. innocua genome (Table 3)....”
- “...Similar Similar to to to to Lmo0047 Lmo0207 Lmo0255 Lmo0303 Lmo0324 Lmo0460 Lmo0510 Lmo0617 Lmo0791 Lmo0821 Lmo0953 Lmo1068 Lmo1265 Lmo1340 Lmo1649 Lmo1653...”
SSA_0004 Lipoprotein, putative from Streptococcus sanguinis SK36
Aligns to 30:152 / 163 (75.5%), covers 91.1% of PF06998, 87.1 bits
- Contribution of lipoproteins and lipoprotein processing to endocarditis virulence in Streptococcus sanguinis
Das, Journal of bacteriology 2009 - “...(pool 2) (Fig. 2). Strains with mutations in SSA_0004, SSA_1546, and Downloaded from http://jb.asm.org/ on February 12, 2017 by University of California,...”
- “...control in all animals tested and seven additional mutants (SSA_0004, -0588, -1122, -1976, -2243, lgt, and lspA) that showed reduced signal intensity in some of...”
NM219_00915, NM220_00915 YehR family lipoprotein from Parvimonas micra
Aligns to 27:159 / 161 (82.6%), covers 100.0% of PF06998, 63.9 bits
- Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma
Conde-Pérez, Molecular oncology 2024 - “...459 25 NM219_00075 NM220_00075 Hypothetical protein 1104 25 NM219_00080 NM220_00080 DUF1307 domaincontaining protein 486 26 NM219_00915 NM220_00915 DUF1307 domaincontaining protein 477 26 NM219_00920 NM220_00920 DUF2087 domaincontaining protein 270 27 NM219_01675 NM220_01675 GNAT family Nacetyltransferase 480 27 NM219_01680 NM220_01680 ABC transporter permease 1263 28 NM219_06715 NM220_06715 Hypothetical...”
- “...25 NM219_00075 NM220_00075 Hypothetical protein 1104 25 NM219_00080 NM220_00080 DUF1307 domaincontaining protein 486 26 NM219_00915 NM220_00915 DUF1307 domaincontaining protein 477 26 NM219_00920 NM220_00920 DUF2087 domaincontaining protein 270 27 NM219_01675 NM220_01675 GNAT family Nacetyltransferase 480 27 NM219_01680 NM220_01680 ABC transporter permease 1263 28 NM219_06715 NM220_06715 Hypothetical protein...”
Or search for genetic data about PF06998 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory