Family Search for PF07233 (DUF1425)
PF07233 hits 15 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
VP0966 conserved hypothetical protein from Vibrio parahaemolyticus RIMD 2210633
Aligns to 31:126 / 130 (73.8%), covers 100.0% of PF07233, 104.0 bits
- Identification of Vibrio parahaemolyticus and Vibrio spp. Specific Outer Membrane Proteins by Reverse Vaccinology and Surface Proteome
Wang, Frontiers in microbiology 2020 - “...hypothetical protein (VP0802), Maltoporin (LamB), OmpA, OmpU, and OmpK, as well as hypothetical VP1243 and VP0966 ( Li et al., 2014 ). Recently, Yonekita et al. (2020) reported that a diagnostic antibody prepared against a whole cell antigen was specific to 12 serotypes of V. parahaemolyticus...”
- “...All of these proteins were predicted as OMPs in this study, except VP2850, VP1243, and VP0966, which were only predicted by CELLO. Importantly, we confirmed the homology of these OMPs among the 32 species of Vibrio and closely related non- Vibrio strains at the sequence level....”
- LptD is a promising vaccine antigen and potential immunotherapeutic target for protection against Vibrio species infection
Zha, Scientific reports 2016 - “...Moreover, our previous study identified several OMPs, LptD, LamB, OmpA, OmpK, OmpU, VP0802, VP1243 and VP0966, to be immunogenic proteins from V. parahaemolyticus using an immunoproteomics approach 19 . Among these proteins, LptD appeared to be a highly immunogenic protein. The structure and function of LptD...”
- “...OMPs. In our previous study, LptD, as well as other three OMPs VP0802, VP1243 and VP0966 with relatively low abundance, were identified as immunogenic proteins for the first time using immunoproteomics from V. parahaemolyticus 19 . These newly identified immunogenic proteins, along with other immunogenic OMPs...”
- Identification of a novel vaccine candidate by immunogenic screening of Vibrio parahaemolyticus outer membrane proteins
Li, Vaccine 2014 (PubMed)- “...low abundance in OMP profiles, LptD, VP0802, VP1243 and VP0966, were determined to have immunogenicity for the first time. One OMP of interest, VP0802, is...”
- “...gi| 28898017 VP1243 19,769 119 10 Hypothetical protein VP0966 gi| 28897740 VP0966 14,723 63 Non-immunogenic proteins 12 Chitoporin gi| 28897534 VP0760 40,764...”
Shew_1734 hypothetical protein from Shewanella loihica PV-4
Aligns to 30:125 / 129 (74.4%), covers 99.0% of PF07233, 96.5 bits
- Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins
Paek, Proteins 2012 - “...with Cj0090. Among these, two bacterial proteins were noteworthy: (1) uncharacterized protein referred to as Shew_1734 (PDB 3o0l; Z score 9.9 and r.m.s.d. 2.3) and (2) ApaG (PDB 1tza; Z score 6 and r.m.s.d. 2.6). Both proteins are similar to Cj0090 in size. The crystal structure...”
- “...the closest structural homolog of the Cj0090 structure. Given low sequence identity between Cj0090 and Shew_1734 (15% identical excluding signal peptide), it was not surprising that BLAST searches failed to identify Shew_1734 as a homolog. Analogous to Cj0090, Shew_1734 is a putative bacterial lipoprotein and contains...”
VV93_v1c20800 YcfL family protein from Vibrio vulnificus
Aligns to 31:126 / 129 (74.4%), covers 99.0% of PF07233, 95.1 bits
- Genome analysis of clinical genotype Vibrio vulnificus isolated from seafood in Mangaluru Coast, India provides insights into its pathogenicity
Prithvisagar, The veterinary quarterly 2023 - “...AIL70004.1 0.002905 0.329515 0.701058 28 VV93_v1c27660 0.070245 0.346296 0.169231 26 VV93_v1c15720 0.008373 0.320205 0.658462 26 VV93_v1c20800 0.006278 0.315346 0.649231 26 VV93_v1c28020 0.073653 0.338768 0.16 25 surA 0.038047 0.321306 0.237154 23 VV93_v1c05840 0.010784 0.330973 0.604743 23 VV93_v1c00830 0.007517 0.335727 0.675889 23 VV93_v1c22970 0.007349 0.328936 0.687747 23 VV93_v1c10670...”
- “...VV93_v1c37740), AsmA, and leucine-rich repeat domain superfamily (VV93_v1c08230, VV93_v1c34010, VV93_v1c37740), thiamine kinase, and ycfl-like superfamily (VV93_v1c20800 and VV93_v1c20810). The majority of the proteins in cluster 2 (C2) are strongly associated with amino acid (VV93_v1c32290, VV93_v1c37060, VV93_v1c42090, VV93_v1c42110, VV93_v1c42780) and nitrogen compound transport (VV93_v1c30270, VV93_v1c32290, VV93_v1c37060, VV93_v1c42090,...”
SPA1645 putative lipoprotein from Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Aligns to 30:124 / 124 (76.6%), covers 99.0% of PF07233, 94.3 bits
- Identification of in vivo-induced bacterial proteins during human infection with Salmonella enterica serotype Paratyphi A
Alam, Clinical and vaccine immunology : CVI 2013 - “...and adhesion SPA0021 SPA0181 SPA0201 SPA0703 SPA1533 SPA1604 SPA1645 SPA3787 SPA4148 bcfA stkE stfA stcD osmE envE ycfL yifL yjeI Fimbrial subunit Putative...”
- “...the cell envelope and membrane (SPA1533, SPA1604, SPA1645, SPA3787, and SPA4148), energy metabolism and cellular processes (SPA0489, SPA0608, SPA0652, SPA1239,...”
NP_460176 putative outer membrane lipoprotein from Salmonella typhimurium LT2
SEET0819_12675 YcfL family protein from Salmonella enterica subsp. enterica serovar Tennessee str.
Aligns to 30:124 / 124 (76.6%), covers 99.0% of PF07233, 94.1 bits
YPO1612 putative lipoprotein from Yersinia pestis CO92
YPTB2452 putative lipoprotein from Yersinia pseudotuberculosis IP 32953
Aligns to 35:129 / 129 (73.6%), covers 99.0% of PF07233, 91.0 bits
S1188 hypothetical protein from Shigella flexneri 2a str. 2457T
Aligns to 31:125 / 125 (76.0%), covers 99.0% of PF07233, 91.0 bits
- Addendum
, Open forum infectious diseases 2019
YcfL / b1104 DUF1425 domain-containing protein YcfL from Escherichia coli K-12 substr. MG1655 (see paper)
b1104 hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 31:125 / 125 (76.0%), covers 99.0% of PF07233, 90.6 bits
EAM_1468 lipoprotein from Erwinia amylovora ATCC 49946
Aligns to 28:122 / 122 (77.9%), covers 97.9% of PF07233, 86.1 bits
NJ56_16480 DUF1425 domain-containing protein from Yersinia ruckeri
Aligns to 35:129 / 129 (73.6%), covers 99.0% of PF07233, 77.1 bits
YP_002343550 lipoprotein from Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cj0090 putative lipoprotein from Campylobacter jejuni subsp. jejuni NCTC 11168
Aligns to 26:120 / 122 (77.9%), covers 99.0% of PF07233, 66.3 bits
- Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins
Paek, Proteins 2012 - GeneRIF: Here, we report the crystal structure of Campylobacter jejuni Cj0090 at 1.9 A resolution, revealing a novel variant of the immunoglobulin fold with beta-sandwich architecture.
- “...( A ) Sequence alignment of Cj0090 and representative putative lipoproteins: Cj, Campylobacter jejuni (accession#: YP_002343550); Sl, Shewanella loihica (accession#: YP_001093860); Vc, Vibrio cholerae (accession#: NP_231529); Se, Salmonella enterica (accession#: NP_460176); and Ec, Escherichia coli (accession#: NP_287238). The signal peptides are indicated in red box. The...”
- Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis
Banaś, International journal of molecular sciences 2021 - “...jejuni NCTC 11168 was described by Oakland et al. as a part of the cj0089 cj0090 cj0091 operon activated by CmeR. All proteins encoded by this operon are membrane-located lipoproteins with an undefined function involved in chicken colonization [ 52 ]. The G. mellonella infection model...”
- The surface lipoproteins of gram-negative bacteria: Protectors and foragers in harsh environments
Cole, The Journal of biological chemistry 2021 - “...BSA64 Unknown 6HPN ( 128 ) Campylobacter jejuni JlpA Cell adhesion 3UAU ( 140 ) Cj0090 Unknown 4GIO ( 141 ) Escherichia coli LptE LPS assembly 4NHR ( 142 ) Francisella tularensis Flpp3 Unknown 6PNY ( 143 ) Haemophilus parasuis TbpB Nutrient acquisition 4O4X ( 117...”
- “...141 Paek S. Kawai F. Choi K.J. Yeo H.J. Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins Proteins 80 2012 2804 2809 22987763 142 Maloji G. Andres D. Grabowicz M. George A.H. Ruiz N. Silhavy...”
- Virulence Traits of Inpatient Campylobacter jejuni Isolates, and a Transcriptomic Approach to Identify Potential Genes Maintaining Intracellular Survival
Kovács, Microorganisms 2020 - “...expression of factors that were recently speculated to be involved in adhesion ( Cj0268 , Cj0090 , Cj0091 , Cj1136 , Cj0286c , Cj0379c , jlpA , capA , cjaA , flpA , fbpA , cadF , peb2 , and peb3) . However, expression of adhesion...”
- “...( jlpA , capA , cjaA , flpA , fbpA , cadF , cj0268 , cj0090 , cj0091 , cj1136 , cj0286c , and cj0379c ) have previously been confirmed or suggested to play a role in C. jejuni adhesion [ 14 , 15 , 16...”
- Campylobacter jejuni 11168H Exposed to Penicillin Forms Persister Cells and Cells With Altered Redox Protein Activity
Morcrette, Frontiers in cellular and infection microbiology 2020 - “...Cj0440c Transcriptional regulator 0.1449 Cj0734c hisJ Histidine-binding protein 3.0803 Cj0234c frr Ribosome recycling factor 0.1472 Cj0090 Lipoprotein 3.0552 Cj1516 Oxidoreductase 0.158 Cj0853c hemL Glutamate-1-semialdehyde aminotransferase 2.8635 Cj0014c Integral membrane protein 0.159 The proteome of these cells was compared to the proteome of a control culture not...”
- Proteomic and genomic analysis reveals novel Campylobacter jejuni outer membrane proteins and potential heterogeneity
Watson, EuPA open proteomics 2014 - “...CJJ81176_0126). Oakland et al. [51] recently characterised homologues of these lipoproteins in strain NCTC11168 (Cj0089, Cj0090, and Cj0091). Few autotransporter proteins are annotated in C. jejuni yet they are common features of Gram-negative bacterial outer membranes. In this study we detected the expression of one putative...”
- Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins
Paek, Proteins 2012 - “...Proteins Proteins 0887-3585 1097-0134 22987763 3486952 10.1002/prot.24182 NIHMS409578 Article Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins Paek Seonghee Kawai Fumihiro Choi Kyoung-Jae Yeo Hye-Jeong * Department of Biology and Biochemistry, University of Houston, Houston,...”
- “...20 lipoproteins. However, the functions of the majority of C. jejuni lipoproteins remain unknown. The Cj0090 protein is encoded by a lipoprotein operon composed of cj0089, cj0090 , and cj0091 . Here, we report the crystal structure of Cj0090 at 1.9 resolution, revealing a novel variant...”
- Functional characterization of a lipoprotein-encoding operon in Campylobacter jejuni
Oakland, PloS one 2011 - “...the multidrug efflux pump CmeABC, modulates the expression of a three-gene operon ( cj0089 , cj0090 , and cj0091 ) encoding a cluster of lipoproteins in C. jejuni . Methodology/Principal Findings In this work, we characterized the function and regulation of the cj0089 - cj0090 -...”
- “...CmeR-regulated targets were cj0089 and cj0091 encoding putative lipoproteins. cj0089 and cj0091 , along with cj0090 (also encoding a putative lipoprotein) appear to be organized into an operon, but their detailed regulatory mechanisms and the role in Campylobacter pathophysiology remain unknown. Considering the fact that bacterial...”
CJJ81176_0125 lipoprotein, putative from Campylobacter jejuni subsp. jejuni 81-176
Aligns to 26:120 / 122 (77.9%), covers 99.0% of PF07233, 65.5 bits
- Proteomic and genomic analysis reveals novel Campylobacter jejuni outer membrane proteins and potential heterogeneity
Watson, EuPA open proteomics 2014 - “...Three lipoproteins, which are encoded by a locus of three genes, were also identified (CJJ81176_0124, CJJ81176_0125 and CJJ81176_0126). Oakland et al. [51] recently characterised homologues of these lipoproteins in strain NCTC11168 (Cj0089, Cj0090, and Cj0091). Few autotransporter proteins are annotated in C. jejuni yet they are...”
- “...high sequence similarity with proteins present within both strains of C. coli although the lipoprotein CJJ81176_0125, CJJ81176_1185 (Omp50), the hypothetical protein CJJ81176_0127 and the serine protease CJJ81176_1367 are absent. Several OM proteins of strain 81-176 were revealed to have high sequence similarity (up to 91%) with...”
APL_0125 hypothetical protein from Actinobacillus pleuropneumoniae L20
APJL_0126 predicted periplasmic lipoprotein from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Aligns to 31:122 / 124 (74.2%), covers 72.9% of PF07233, 41.6 bits
NTHI1133 predicted periplasmic lipoprotein from Haemophilus influenzae 86-028NP
Aligns to 35:116 / 116 (70.7%), covers 71.9% of PF07233, 34.8 bits
P44084 Uncharacterized protein HI_0960 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
HI0960 H. influenzae predicted coding region HI0960 from Haemophilus influenzae Rd KW20
Aligns to 35:116 / 116 (70.7%), covers 71.9% of PF07233, 33.8 bits
Or search for genetic data about PF07233 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory