Family Search for PF07786 (DUF1624)
PF07786.12 hits 19 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
PSF113_2972 DUF1624 domain-containing protein from Pseudomonas fluorescens F113
Aligns to 28:267 / 401 (59.9%), covers 94.2% of PF07786, 66.1 bits
- Genome-wide analysis of the FleQ direct regulon in Pseudomonas fluorescens F113 and Pseudomonas putida KT2440
Blanco-Romero, Scientific reports 2018 - “...replication protein-like protein PSF113_1047 Multicopper oxidase PSF113_1201 FerredoxinNADP(+) reductase PSF113_2126 Dihydrodipicolinate synthase PSF113_2158 nuoA NuoA PSF113_2972 Glycosaminoglycan degradation PSF113_3889 Zinc carboxypeptidase domain protein PSF113_3918 tig Tig PSF113_3922 folD FolD PSF113_4083 Sterol desaturase PSF113_4204 Protein binding PSF113_4932 prs Prs PSF113_4978 Pentapeptide repeat-containing protein REGULATION/SIGNAL TRANSDUCTION PSF113_1200 LysR...”
SO1157 conserved hypothetical protein (NCBI ptt file) from Shewanella oneidensis MR-1
Aligns to 10:240 / 388 (59.5%), covers 87.9% of PF07786, 64.7 bits
- Use of microarrays with different probe sizes for monitoring gene expression
He, Applied and environmental microbiology 2005 - “...detected by the 50-mer, 60-mer, and 70-mer oligonucleotide probes. SO1157 was detected as an up-regulated locus by the PCR probe (2.2-fold) and the 70-mer probe...”
- “...SO2320 SO3051 SO2697 SO4661 SO1679 SO2389 SO2953 SO2113 SO2654 SO1157 SO2930 SO1277 SO2886 b 70-mer gene arrays were used, the detection limit for nirS (nitrite...”
PSPPH_2918 membrane protein, putative (NCBI) from Pseudomonas syringae pv. phaseolicola 1448A
Aligns to 14:246 / 388 (60.1%), covers 85.7% of PF07786, 63.4 bits
PA4838 hypothetical protein (NCBI) from Pseudomonas aeruginosa PAO1
Aligns to 10:232 / 384 (58.1%), covers 84.3% of PF07786, 58.9 bits
PA14_63970 hypothetical protein (NCBI) from Pseudomonas aeruginosa UCBPP-PA14
Aligns to 10:232 / 384 (58.1%), covers 84.3% of PF07786, 58.9 bits
PP2419 membrane protein, putative (NCBI ptt file) from Pseudomonas putida KT2440
Aligns to 49:287 / 421 (56.8%), covers 94.6% of PF07786, 57.5 bits
- Glucose dehydrogenase of a rhizobacterial strain of Enterobacter asburiae involved in mineral phosphate solubilization shares properties and sequence homology with other members of enterobacteriaceae
Tripura, Indian journal of microbiology 2007 - “...Dr. Naresh Kumar, G E. coli JM109 Lab Stock E. coli PP2419 [E. coli JM101 (gcd ( ::cm)] Dr. Goosen, N E. coli M15 (pREP4) Lab Stock E. coli AT15 (pREP4) [E....”
- “...E. coli M15 was generated by P1 transduction using E. coli PP2419 as the donor and the resulting strain, designated as E. coli AT15 (gcd ( ::cm), was used as...”
- Cloning, mapping, and sequencing of the gene encoding Escherichia coli quinoprotein glucose dehydrogenase
Cleton-Jansen, Journal of bacteriology 1990 - “...by P1 transduction, which resulted in the chloramphenicol-resistant strain PP2419. The presence of the cat gene within the SmaI site of the chromosomal ged gene...”
- “...is advantageous for E. coli, growth rates of JM101 and PP2419 (gcd::cat) were measured in the presence or absence of PQQ both in mineral medium and rich medium...”
lpp1632 hypothetical protein (NCBI) from Legionella pneumophila str. Paris
Aligns to 10:245 / 372 (63.4%), covers 86.1% of PF07786, 52.3 bits
lpl1626 hypothetical protein (NCBI) from Legionella pneumophila str. Lens
Aligns to 10:248 / 372 (64.2%), covers 85.7% of PF07786, 50.3 bits
lpg1661 Hypothetical protein (NCBI) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Aligns to 10:244 / 372 (63.2%), covers 85.2% of PF07786, 49.1 bits
XP_004928101 heparan-alpha-glucosaminide N-acetyltransferase from Bombyx mori
Aligns to 191:332 / 581 (24.4%), covers 55.2% of PF07786, 33.1 bits
XP_005273466 heparan-alpha-glucosaminide N-acetyltransferase isoform X1 from Homo sapiens
Aligns to 239:400 / 672 (24.1%), covers 52.9% of PF07786, 30.9 bits
- Molecular characterization of a large group of Mucopolysaccharidosis type IIIC patients reveals the evolutionary history of the disease.
Martins, Human mutation 2019 (PubMed)- GeneRIF: Study reports molecular analysis defects in the HGSNAT gene in the largest group of mucopolysaccharidosis type IIIC (MPSIIIC) patients studied so far increasing the total number of HGSNAT variants associated with MPSIIIC to 71. Additionally, some of these variants show common ancestor haplotypes; others are several founder mutations.
- Klüver-Bucy syndrome associated with a recessive variant in HGSNAT in two siblings with Mucopolysaccharidosis type IIIC (Sanfilippo C).
Hu, European journal of human genetics : EJHG 2017 - GeneRIF: A homozygous variant in HGSNAT identified in two siblings with Kluver-Bucy syndrome and Mucopolysaccharidosis type IIIC.
- HGSNAT has a TATA-less promoter with multiple starts of transcription.
Richtrova, Gene 2016 (PubMed)- GeneRIF: Promoter variants rs4523300 and rs149596192 did not have a measurable impact on HGSNAT enzyme activity in MPS IIIC patients carrying them.
- Non-syndromic retinitis pigmentosa due to mutations in the mucopolysaccharidosis type IIIC gene, heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT).
Haer-Wigman, Human molecular genetics 2015 - GeneRIF: Mutation id HGSNAT is associated with non-syndromic retinitis pigmentosa .
- Molecular analysis of Sanfilippo syndrome type C in Spain: seven novel HGSNAT mutations and characterization of the mutant alleles.
Canals, Clinical genetics 2011 (PubMed)- GeneRIF: Identification of novel HGSNAT mutations in Sanfilippo syndrome type C Spanish patients.
- Characterization of the biosynthesis, processing and kinetic mechanism of action of the enzyme deficient in mucopolysaccharidosis IIIC.
Fan, PloS one 2011 - GeneRIF: Characterization of the biosynthesis, processing and kinetic mechanism of heparin acetyl-CoA:alpha-glucosaminide N-acetyltransferase
- Functional analysis of the HGSNAT gene in patients with mucopolysaccharidosis IIIC (Sanfilippo C Syndrome).
Fedele, Human mutation 2010 (PubMed)- GeneRIF: Data suggests that mutations may function together to abolish HGSNAT activity.
- Analysis of the biogenesis of heparan sulfate acetyl-CoA:alpha-glucosaminide N-acetyltransferase provides insights into the mechanism underlying its complete deficiency in mucopolysaccharidosis IIIC.
Durand, The Journal of biological chemistry 2010 - GeneRIF: intralysosomal oligomerization and proteolytic cleavage as two steps crucial for functional activation of HGSNAT.
- More
HGNAT_HUMAN / Q68CP4 Heparan-alpha-glucosaminide N-acetyltransferase; Transmembrane protein 76; EC 2.3.1.78 from Homo sapiens (Human) (see 13 papers)
Q68CP4 heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) from Homo sapiens (see 5 papers)
Aligns to 267:428 / 663 (24.4%), covers 52.9% of PF07786, 30.9 bits
- function: Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.
catalytic activity: acetyl-CoA + alpha-D-glucosaminyl-[heparan sulfate](n) = CoA + H(+) + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) (RHEA:15125)
subunit: Homooligomer. Homooligomerization is necessary for enzyme activity.
AT5G27730 hypothetical protein (RefSeq) from Arabidopsis thaliana
Aligns to 36:213 / 472 (37.7%), covers 52.9% of PF07786, 29.7 bits
- Intrusive Growth of Phloem Fibers in Flax Stem: Integrated Analysis of miRNA and mRNA Expression Profiles
Gorshkov, Plants (Basel, Switzerland) 2019 - “...AT2G46570 LAC6 2.17 9.55 3.95 6.1 145.8 32.4 0.0 0.6 Lus10021514 Heparan-alpha-glucosaminide N-acetyltransferase-like protein (DUF1624) AT5G27730 2.06 3.15 1.80 11.8 65.6 15.6 7.4 30.3 Lus10013125 Flavin-binding monooxygenase family protein AT5G11320 YUC4 1.97 9.35 5.62 2.0 127.7 32.5 0.0 18.5 Lus10037136 Argonaute family protein AT1G69440 AGO7,ZIP 1.83...”
- Transcriptome-wide high-throughput deep m(6)A-seq reveals unique differential m(6)A methylation patterns between three organs in Arabidopsis thaliana
Wan, Genome biology 2015 - “...AT5G35630, AT2G28210, AT1G77760, AT5G14740, AT1G70410, AT1G11860, AT3G47340, AT2G41560 Glycosaminoglycan degradation 4 0.16 0.03 AT5G13690, AT1G05590, AT5G27730, AT1G65590 Glyoxylate and dicarboxylate metabolism 9 0.37 0.03 AT3G21720, AT3G47520, AT5G38430, AT5G03860, AT5G38410, AT4G17360, AT3G14415, AT5G38420 Higher in flowers RNA degradation 7 0.60 0.03 AT5G38890, AT1G03330, AT3G07750, AT1G65700, AT1G03360, AT1G80780,...”
Tanf_08375 DUF1624 domain-containing protein from Tannerella forsythia
Aligns to 8:263 / 387 (66.1%), covers 85.7% of PF07786, 29.7 bits
- N-Acetylmuramic Acid (MurNAc) Auxotrophy of the Oral Pathogen Tannerella forsythia: Characterization of a MurNAc Kinase and Analysis of Its Role in Cell Wall Metabolism
Hottmann, Frontiers in microbiology 2018 - “...exogenous supply of MurNAc for growth and maintenance of cell morphology. A MurNAc transporter (Tf_MurT; Tanf_08375) and an ortholog of the Escherichia coli etherase MurQ (Tf_MurQ; Tanf_08385) converting MurNAc-6-phosphate to GlcNAc-6-phosphate were recently described for T. forsythia. In between the respective genes on the T. forsythia...”
- “...forsythia , PTS-type transporters are missing; however, recently, a PTS-independent uptake system for MurNAc (Tf_MurT; Tanf_08375) was identified in the T. forsythia type strain ATCC 43037, which belongs to the sodium symporter superfamily ( Ruscitto et al., 2016 ). The corresponding Tf_murT gene is present within...”
- Identification of a Novel N-Acetylmuramic Acid Transporter in Tannerella forsythia
Ruscitto, Journal of bacteriology 2016 - “...were identified on a three-gene cluster spanning Tanf_08375 to Tanf_08385 located downstream from a putative peptidoglycan recycling locus. We show that...”
- “...respectively, are transcriptionally linked. Complementation of the Tanf_08375 and Tanf_08380 genes together in trans, but not individually, rescued the...”
HGNAT_MOUSE / Q3UDW8 Heparan-alpha-glucosaminide N-acetyltransferase; Transmembrane protein 76; EC 2.3.1.78 from Mus musculus (Mouse) (see 2 papers)
Q3UDW8 heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) from Mus musculus (see paper)
NP_084160 heparan-alpha-glucosaminide N-acetyltransferase from Mus musculus
Aligns to 260:434 / 656 (26.7%), covers 52.9% of PF07786, 29.2 bits
- function: Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.
catalytic activity: acetyl-CoA + alpha-D-glucosaminyl-[heparan sulfate](n) = CoA + H(+) + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) (RHEA:15125)
subunit: Homooligomer. Homooligomerization is necessary for enzyme activity (By similarity). - HGSNAT enzyme deficiency results in accumulation of heparan sulfate in podocytes and basement membranes.
Nagel, Histology and histopathology 2019 (PubMed)- GeneRIF: Hgsnat gene inactivation and heparan sulfate toxicity have an effect on the integrity of the renal corpuscle
AT5G47900 hypothetical protein (RefSeq) from Arabidopsis thaliana
Aligns to 45:208 / 440 (37.3%), covers 52.9% of PF07786, 28.2 bits
- AGAMOUS controls GIANT KILLER, a multifunctional chromatin modifier in reproductive organ patterning and differentiation
Ng, PLoS biology 2009 - “...5-CHH, AT5G57520; 5-CHR, AT5G42920; 5-CLV, AT5G62230; 5-CO, AT5G41380; 5-CYT, AT5G57570; 5-DAG, AT5G44780; 5-DIS, AT5G45500; 5-DRO, AT5G47900; 5-GAL, AT5G26920; 5-GAS, AT5G15230; 5-HAP, AT5G67180; 5-HYP, AT5G40860; 5-KIN, AT5G25440; 5-MCR, AT5G55670; 5-MYB, AT5G49330; 5-NAL, AT5G39610; 5-NAM, AT5G39540; 5-PEC, AT5G66920; 5-REK, AT5G12000; 5-RLK, AT5G35390; 5-RLL, AT5G03140; 5-SET, AT5G43990; 5-SHG, AT5G14640;...”
BC4744 hypothetical Membrane Spanning Protein (NCBI ptt file) from Bacillus cereus ATCC 14579
Aligns to 9:172 / 340 (48.2%), covers 70.0% of PF07786, 26.7 bits
- Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48
Grande, BMC microbiology 2009 - “...specific overexpression of the BC4207 membrane protein, we randomly selected two membrane proteins (BC4147 and BC4744) and introduced them into B. cereus ATCC14579 similar to the BC4207 protein. Expression of these proteins resulted in no significant growth difference in the presence of various amounts of AS-48...”
- “...cDNA using the 2 -Ct method [ 34 ]. Overexpression of the BC4207, BC4147 and BC4744 proteins BC4207, BC4147 and BC4744 genes were amplified with oMJGB3 (5'-GATCGAAGCTTACGGTAAATAACTTATTACAG-3') and oMJGB4 (5'-GATCCAGGCATGCTCACGTCAACAATTAACTTT-3'), oBCE9 (5'-CATATAGGAGTAATGATATG-3') and oBCE10 (5'-AGAGAAGATACGGCATAG-3'), oBCE11 (5'-TACAAGGAGTTGCTTTATGG-3') and oBCE11 (5'-TTATATCGGCGCAACTAC-3'), respectively. PCR products were cloned into...”
RSP_4209 Acyltransferase 3 family (NCBI) from Rhodobacter sphaeroides 2.4.1
Aligns to 13:122 / 392 (28.1%), covers 37.7% of PF07786, 23.6 bits
- Convergence of the transcriptional responses to heat shock and singlet oxygen stresses
Dufour, PLoS genetics 2012 - “...RSP_0423, RSP_0557, RSP_0799, RSP_0896, RSP_1591, RSP_1956, RSP_1985, RSP_2225, RSP_2268, RSP_3075, RSP_3076, RSP_3089, RSP_3310, RSP_3329, RSP_4144, RSP_4209 Summary of the functional annotations of members of the RpoH I and RpoH II regulons in R. sphaeroides defined by the intersections of the results from the expression profiling and...”
LOC100878398 heparan-alpha-glucosaminide N-acetyltransferase-like from Megachile rotundata
Aligns to 169:300 / 552 (23.9%), covers 53.4% of PF07786, 21.8 bits
- Immediate Transcriptional Response to a Temperature Pulse under a Fluctuating Thermal Regime
Melicher, Integrative and comparative biology 2019 - “..., LOC413056, Fig.4b ) ( Salama etal. 1990 ; Schaaf etal. 2008 ), and acytltransferases (LOC100878398, LOC100879483). Enzymes that affect membrane glycerophospholipid composition include alanine-glyoxylate aminotransferase 2-like (LOC100879339), which is up-regulated during the warm pulse and phospholipase A2 (LOC100877091), which is up-regulated under CT ( Huang...”
- “...Elongation of very long chain fatty acids protein 7-like XM_003703558 LOC100878819 Fatty acid synthase XM_003700398 LOC100878398 Heparan-alpha-glucosaminide N-acetyltransferase-like XM_012292966 LOC100880205 Phosphodiesterase epsilon-1-like XM_003702488 LOC100880638 Aquaporin AQPcic-like XM_003703107 LOC100875155 Peroxiredoxin-6-like XM_003704386 LOC100879301 Alpha-amylase-like XM_003702306 LOC100879369 Carboxypeptidase M-like XM_012287600 LOC100882780 Serine proteinase stubble XM_003701259 LOC100882217 Protein yellow-like XM_003704962...”
Or search for genetic data about PF07786 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory