Family Search for PF07869 (DUF1656)
Running HMMer for PF07869
PF07869 hits 22 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
CV_2846 conserved hypothetical protein from Chromobacterium violaceum ATCC 12472
Aligns to 4:59 / 66 (84.8%), covers 100.0% of PF07869, 87.2 bits
BMEII0532 Hypothetical Membrane Associated Protein from Brucella melitensis 16M
Aligns to 4:59 / 69 (81.2%), covers 100.0% of PF07869, 85.5 bits
- Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development
Cannella, Frontiers in cellular and infection microbiology 2012 - “...BMEII0054 Putative uncharacterized protein 5,237 BMEII1049 Putative uncharacterized protein 7,955 BMEII0558 Putative uncharacterized protein 7,596 BMEII0532 Hypothetical membrane associated protein 7,916 BMEII0892 Putative uncharacterized protein 6,762 BMEI1502 Alkaline phosphatase like protein 21,488 BMEII0720 Transcriptional regulator 7,304 There could be a potential difference in the antibody responses...”
RR42_RS03030 required for 4-hydroxybenzoate transport, together with NodT, MFP, and FUSC proteins (RR42_RS03040, RR42_RS03035, and RR42_RS03025) from Cupriavidus basilensis FW507-4G11
Aligns to 4:59 / 69 (81.2%), covers 100.0% of PF07869, 83.6 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). Specifically important for utilization of 4-hydroxybenzoate (at 20 mM). Not clear if this system is for uptake or for efflux (as this compound is likely to be toxic at 20 mM)
BCAS0016 hypothetical protein from Burkholderia cenocepacia J2315
Aligns to 4:59 / 70 (80.0%), covers 100.0% of PF07869, 79.2 bits
XCC4168 conserved hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913
Aligns to 7:62 / 72 (77.8%), covers 100.0% of PF07869, 77.9 bits
PS417_00715 required for octanoate transport, together with NodT, MFP, and FUSC proteins (PS417_00725, PS417_00720, PS417_00710) from Pseudomonas simiae WCS417
Aligns to 4:59 / 69 (81.2%), covers 100.0% of PF07869, 75.5 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. This and orthologous operons are important for growth in 20 mM octanoate (as the carbon source), which is probably toxic. This operon could also be for uptake rather than efflux.
PP0177 conserved hypothetical protein from Pseudomonas putida KT2440
Aligns to 4:59 / 70 (80.0%), covers 100.0% of PF07869, 74.8 bits
PfGW456L13_506 required for octanoate transport, together with NodT, MFP, and FUSC proteins (PfGW456L13_504, PfGW456L13_505, PfGW456L13_507) from Pseudomonas fluorescens GW456-L13
Aligns to 4:59 / 69 (81.2%), covers 100.0% of PF07869, 74.8 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. This and orthologous operons are important for utilization of octanoate, which is probably toxic at 20 mM, but it could also be for uptake rather than efflux.
ZMO1431 hypothetical protein from Zymomonas mobilis subsp. mobilis ZM4
Aligns to 5:60 / 77 (72.7%), covers 98.2% of PF07869, 74.0 bits
- Development and characterization of acidic-pH-tolerant mutants of Zymomonas mobilis through adaptation and next-generation sequencing-based genome resequencing and RNA-Seq
Yang, Biotechnology for biofuels 2020 - “...the expression of the whole operon encoding an RND efflux system consisted of ZMO1432 , ZMO1431 , ZMO1430 and ZMO1429 was significantly upregulated at acidic pH 3.8 in two mutant strains compared with ZM4, and 3.6M had the highest expression level among these strains (Additional file...”
- Multiomic Fermentation Using Chemically Defined Synthetic Hydrolyzates Revealed Multiple Effects of Lignocellulose-Derived Inhibitors on Cell Physiology and Xylose Utilization in Zymomonas mobilis
Zhang, Frontiers in microbiology 2019 - “...; Yang et al., 2014a ). In contrast, furfural stress induced downregulation of ZMO0285, ZMO1429, ZMO1431, and ZMO1432 after 24 h ( He et al., 2012b ). However, both ZMO0282 and ZMO0283 were found to be upregulated in response to phenolic aldehydes, including 4-hydroxybenzaldehyde, syringaldehyde, and...”
- Towards an informative mutant phenotype for every bacterial gene
Deutschbauer, Journal of bacteriology 2014 - “...ZMO0910 ZMO0964 ZMO0981 ZMO1018, ZMO1017, ZMO1016, ZMO1015 ZMO1431, ZMO1430 ZMO1529, ZMO1525 ZMO1591, ZMO1590 ZMO1628, ZMO1630 Efflux pump component; substrate...”
- “...of unknown function) (DUF330), ZMO1591 (DUF140), and ZMO1431 (DUF1656) encode components of transporters. We also predicted specific functions for five other...”
- Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates
Skerker, Molecular systems biology 2013 - “...of four genes by 0.5 or more. The affected genes were ZMO0975 , ZMO1430 , ZMO1431 , and ZMO1432 ; also ZMO1429 is in an operon with ZMO1430-ZMO1432 and is near the threshold. All five of these genes were identified as having non-stable insertions, so we...”
- “...efflux system, outer membrane lipoprotein, NodT family ZMO1430 eff Efflux transporter, RND family, MFP subunit ZMO1431 eff Hypothetical protein ZMO1432 eff Fusaric acid resistance protein conserved region ZMO1490 mem Hypothetical protein ZMO1520 other Hypothetical protein ZMO1541 other Ferrous iron transport protein B ZMO1590 mem ABC transporter...”
BMA_RS04415, BP1026B_I1943, BPS_RS10500 DUF1656 domain-containing protein from Burkholderia pseudomallei 1026b
Aligns to 5:60 / 67 (83.6%), covers 98.2% of PF07869, 73.2 bits
- Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a putative tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei
Grund, PloS one 2020 - “...BPS_RS10495 WP_009937757.1 23489902351191 BMA_RS04420 WP_004192976.1 983721985922 fusD Hypothetical protein BP1026B_I1943 AFI66561.1 21556432155846 BPS_RS10500 WP_004191885.1 23511882351391 BMA_RS04415 WP_004191885.1 983521983724 fusE Fusaric acid resistance protein fusE BP1026B_I1944 AFI66562.1 21558602156741 BPS_RS10505 WP_004534908.1 23514052352286 BMA_RS04410 WP_004191342.1 982626983507 Tar Methyl-accepting chemotaxis protein BP1026B_I1945 AFI66563.1 21570922158768 BPS_RS10510 WP_004196082.1 23526572354333 BMA_RS04405 WP_004196082.1 980610982286...”
- “...acid resistance protein BP1026B_I1942 AFI66560.1 21534452155646 BPS_RS10495 WP_009937757.1 23489902351191 BMA_RS04420 WP_004192976.1 983721985922 fusD Hypothetical protein BP1026B_I1943 AFI66561.1 21556432155846 BPS_RS10500 WP_004191885.1 23511882351391 BMA_RS04415 WP_004191885.1 983521983724 fusE Fusaric acid resistance protein fusE BP1026B_I1944 AFI66562.1 21558602156741 BPS_RS10505 WP_004534908.1 23514052352286 BMA_RS04410 WP_004191342.1 982626983507 Tar Methyl-accepting chemotaxis protein BP1026B_I1945 AFI66563.1 21570922158768...”
- “...BP1026B_I1942 AFI66560.1 21534452155646 BPS_RS10495 WP_009937757.1 23489902351191 BMA_RS04420 WP_004192976.1 983721985922 fusD Hypothetical protein BP1026B_I1943 AFI66561.1 21556432155846 BPS_RS10500 WP_004191885.1 23511882351391 BMA_RS04415 WP_004191885.1 983521983724 fusE Fusaric acid resistance protein fusE BP1026B_I1944 AFI66562.1 21558602156741 BPS_RS10505 WP_004534908.1 23514052352286 BMA_RS04410 WP_004191342.1 982626983507 Tar Methyl-accepting chemotaxis protein BP1026B_I1945 AFI66563.1 21570922158768 BPS_RS10510 WP_004196082.1 23526572354333...”
AaeX / b3242 DUF1656 domain-containing protein AaeX from Escherichia coli K-12 substr. MG1655 (see 2 papers)
AAEX_ECOLI / P46478 Protein AaeX from Escherichia coli (strain K12) (see paper)
b3242 orf, hypothetical protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 6:61 / 67 (83.6%), covers 98.2% of PF07869, 71.9 bits
- Transcriptomic analysis of Escherichia coli O157:H7 and K-12 cultures exposed to inorganic and organic acids in stationary phase reveals acidulant- and strain-specific acid tolerance responses
King, Applied and environmental microbiology 2010 - “...H-ATR, L-ATR, plus A-ATR (universal) ATR(s) ECs4115 ECs2792 b3242 b1995 b1650 ECs3449 ECs3466 ECs3893 b2583 b2603 b3009 Energy production and conversion ECs3081...”
- Inactivation of efflux pumps abolishes bacterial biofilm formation
Kvist, Applied and environmental microbiology 2008 - “...Change (fold) during biofilm formationa 83972 VR50 b2966 b3710 b3242 b1053 b3241 b2170 b4141 b1596 b0842 39.45 11.46 24.78 8.82 30.89 7.42 8.96 3.62 6.86 10.42...”
- Global gene expression profiling of asymptomatic bacteriuria Escherichia coli during biofilm growth in human urine
Hancock, Infection and immunity 2007 - “...1,522 3,916 1,096 1,859 ygiD c3685 aaeX grxA b3039 c3685 b3242 b0849 23.4 22.5 21.2 21.1 3,863 791 3,905 4,675 c2436 c2424 yfiP yqjF mdtL yhcN yqgA rydB sgaB...”
- Role of the rapA gene in controlling antibiotic resistance of Escherichia coli biofilms
Lynch, Antimicrobial agents and chemotherapy 2007 - “...of UPEC and U1 Gene name Annotation Fold change b0585 b3242 b1705 b3050 b0310 b1916 b3071 c0394 c0397 b3241 c1250 c1624 b2181 b0803 b2016 fes yhcR ydiE yqiJ...”
- Global gene expression profiling of the asymptomatic bacteriuria Escherichia coli strain 83972 in the human urinary tract
Roos, Infection and immunity 2006 - “...b2941 b2552 c4141 b1475 b0873 b3240 b3556 b2732 b3437 b3242 b0872 c3046 c3973 c1382 b1445 b0620 c2901 b3241 b1335 Z1954 b1430 b3238 b0849 b0151 fepE ydhC evgA...”
- Evolutionary comparisons suggest many novel cAMP response protein binding sites in Escherichia coli
Brown, Proceedings of the National Academy of Sciences of the United States of America 2004 - “...(b3598) b1458 (b1458) tnaL (b3707) qseA (b3243); yhcR (b3242) yeaA (b1778); b1777 (b1777); gapA (b1779) ydeA (b1528) hpt (b0125); ged (b0124) yefQ (b1111); ycfR...”
- Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12
Sabina, Journal of bacteriology 2003 - “...b1129 b3666 b1444 b1601 b0696 b4017 b0188 b2578 b1749 b3242 b3104 b1736 b3299 b0011 b1447 b3302 b1451 b2261 b0285 b1600 b0174 b2534 b0154 b3312 b1400 82 77...”
- Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate
Pomposiello, Journal of bacteriology 2001 - “...b1452 b1643 b1795 b2174 b2266 b2672 b3004 b3024 b3238 b3242 b1661 b3806 b2414 b4382 b4383 b0014 b0812 b0593 b3289 b1611 b3517 b1493 b1779 b2094 b2093 b2092...”
- “...b1200 b1450 b1452 b1643 b1795 b2174 b2266 b2672 b3004 b3024 b3238 b3242 cfa cyaA cysK deoA deoB dnaK dps entC fmu fumC gadA gadB gapA gatA gatB gatC gatD gatR_2...”
AO353_04830 required for acetate efflux, together with NodT, MFP and FUSC proteins (AO353_04840, AO353_04825, and AO353_04835) from Pseudomonas fluorescens FW300-N2E3
Aligns to 4:59 / 66 (84.8%), covers 100.0% of PF07869, 71.7 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. This operon and orthologous operons are important on acetate as a carbon source and cholin acetate as a stress, which suggests that acetate is a substrate.
AWY96_RS07105 p-hydroxybenzoic acid efflux pump operon protein AaeX from Serratia plymuthica
Aligns to 6:61 / 67 (83.6%), covers 98.2% of PF07869, 71.7 bits
AO356_17240 required for acetate efflux, together with NodT, MFP and FUSC proteins (AO356_17230, AO356_17245, and AO356_17235) from Pseudomonas fluorescens FW300-N2C3
Pf6N2E2_5373 required for cephalothin efflux, together with NodT, MFP and FUSC proteins (Pf6N2E2_5371, Pf6N2E2_5374, Pf6N2E2_5372) from Pseudomonas fluorescens FW300-N2E2
Aligns to 4:59 / 66 (84.8%), covers 100.0% of PF07869, 71.6 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. This operon and orthologous operons are important on acetate as a carbon source and cholin acetate as a stress, which suggests that acetate is a substrate.
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. Specifically important for resisting cephalothin.
PP1265 conserved domain protein from Pseudomonas putida KT2440
Aligns to 4:59 / 66 (84.8%), covers 100.0% of PF07869, 68.9 bits
ECs4115 hypothetical protein from Escherichia coli O157:H7 str. Sakai
Z4601 hypothetical protein from Escherichia coli O157:H7 EDL933
Aligns to 6:61 / 67 (83.6%), covers 98.2% of PF07869, 66.9 bits
PP1151 hypothetical protein from Pseudomonas putida KT2440
Aligns to 5:60 / 68 (82.4%), covers 100.0% of PF07869, 66.2 bits
Pf6N2E2_2878 required for 4-hydroxybenzoate and octanoate transport, together with MFP and FUSC proteins (Pf6N2E2_2877, Pf6N2E2_2879) from Pseudomonas fluorescens FW300-N2E2
Aligns to 5:60 / 68 (82.4%), covers 98.2% of PF07869, 64.6 bits
- mutant phenotype: PFam PF07869.8 (DUF1656). A conserved cofit operon. Important for utilization of octanoate and 4-hydroxybenzoate, which are probably toxic at the high concentrations used (5-20 mM), but it could also be for uptake rather than efflux.
ACIAD0350 conserved hypothetical protein; putative membrane protein from Acinetobacter sp. ADP1
Aligns to 4:59 / 70 (80.0%), covers 98.2% of PF07869, 58.6 bits
- Novel metabolic features in Acinetobacter baylyi ADP1 revealed by a multiomics approach
Stuani, Metabolomics : Official journal of the Metabolomic Society 2014 - “...up-regulated. Out of them, the cluster ACIAD0349-0351 is composed of genes highly conserved in proteobacteria. ACIAD0350 contains a domain of unknown function (DUF1656) also present in a cluster of three genes in E. coli that form an efflux pump (named AaeXAB). It has been proposed that...”
- “...IClR-type regulators ADP1 gene Description Neighboring genes Up-regulation (fold) ACIAD0347 Putative transcriptional regulator ACIAD0349 (CHP) ACIAD0350 (CHP) ACIAD0351(CHP) 34 10 13 ACIAD1684 ( dcaS ) Putative transcriptional regulator ACIAD1687 ( caiB ) 4 ACIAD1688 ( dcaR ) Putative transcriptional regulator ACIAD1689 ( dcaF ) ACIAD1690 (...”
t1311 conserved hypothetical protein from Salmonella enterica subsp. enterica serovar Typhi Ty2
Aligns to 16:70 / 78 (70.5%), covers 92.9% of PF07869, 54.1 bits
YdhI / b1643 DUF1656 domain-containing protein YdhI from Escherichia coli K-12 substr. MG1655 (see paper)
Z2658 orf, hypothetical protein from Escherichia coli O157:H7 EDL933
b1643 predicted inner membrane protein from Escherichia coli str. K-12 substr. MG1655
Aligns to 16:70 / 78 (70.5%), covers 92.9% of PF07869, 52.7 bits
PA1230 hypothetical protein from Pseudomonas aeruginosa PAO1
Aligns to 7:60 / 65 (83.1%), covers 98.2% of PF07869, 44.7 bits
Or search for genetic data about PF07869 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory