Family Search for PF08590 (DUF1771)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF08590 hits 12 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

YLL3_SCHPO / Q9UTP4 Smr domain-containing protein C11H11.03c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
Aligns to 4:67 / 206 (31.1%), covers 100.0% of PF08590, 73.2 bits

YP199_YEAST / Q08954 Smr domain-containing protein YPL199C from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
Aligns to 26:89 / 240 (26.7%), covers 100.0% of PF08590, 72.0 bits

CID7_ARATH / O64843 Polyadenylate-binding protein-interacting protein 7; PABP-interacting protein 7; Poly(A)-binding protein-interacting protein 7; PAM2-containing protein CID7; Protein CTC-INTERACTING DOMAIN 7 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 408:471 / 567 (11.3%), covers 100.0% of PF08590, 68.9 bits

• subunit: Interacts with MPC and PAB2.

N4BP2_HUMAN / Q86UW6 NEDD4-binding protein 2; N4BP2; BCL-3-binding protein; EC 3.-.-.- from Homo sapiens (Human) (see paper)
Aligns to 1619:1682 / 1770 (3.6%), covers 100.0% of PF08590, 63.1 bits

• function: Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.
  subunit: Binds NEDD4 (By similarity). Binds BCL3 and CREBBP.

Y5872_ARATH / O65573 SMR domain-containing protein At5g58720; PRL1-interacting protein PIPC from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 356:419 / 519 (12.3%), covers 100.0% of PF08590, 57.0 bits

• subunit: Interacts with PRL1.

SDE5_ARATH / Q9LUQ3 Putative nuclear RNA export factor SDE5; Protein SILENCING DEFECTIVE 5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 328:391 / 490 (13.1%), covers 96.9% of PF08590, 48.0 bits

• function: Involved in sense transgene post-transcriptional gene silencing (S-PTGS). Not involved in repeat-induced transgene silencing (IR-PTGS). Essential component of the trans-acting short interfering RNA (tasiRNA) pathway. Required for the production of tasiRNAs (PubMed:17397509, PubMed:20798330). Acts together with RDR6 in generating double-stranded RNA from specific single-stranded RNAs. May be involved in the transport of RNA molecules that are converted into a double-stranded form by RDR6. Involved in virus-induced silencing. Not involved in the biogenesis of microRNAs and 24 nt siRNAs produced by DCL3 (PubMed:17397509).
  disruption phenotype: Elongated and curled downward leaves. Upon infection, over-accumulation of cucumber mosaic virus (CMV) RNA and enhanced susceptibility to CMV.

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