Family Search for PF08594 (UPF0300)

PF08594 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

MU131_SCHPO / Q9USY0 Meiotically up-regulated gene 131 protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPBC1861.06c S. pombe specific UPF0300 family protein 4 from Schizosaccharomyces pombe
Aligns to 179:389 / 433 (48.7%), covers 99.5% of PF08594, 278.5 bits

• function: Has a role in meiosis.
• A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
  Cremona, Molecular biology of the cell 2011
  • “...5 8 meu21 SPAC24C9.07c 0 1,3--glucan synthase subunit Bgs2 115.9 M 4 5 9 mug131 SPBC1861.06c 0 S. pombe specific UPF0300 family protein 4 171.4 M 4 5 10 mug125 SPAC1A6.08c 0 Sequence orphan 49 M 4 5 11 mcp4 SPBC16E9.08 0 Pros-pore membrane protein 62.0...”
  • “...N 27.00 0.66 41.00 30 N spo6 SPBC1778.04 N 86.50 1.87 46.33 35 N mug131 SPBC1861.06c N 42.70 0.90 47.26 37 N crs1 SPBC2.09c N 98.05 1.70 57.73 53 Y SPAPB8E5.10 N 74.10 1.24 59.73 56 N mei4 SPBC32H8.11 N 114.65 1.47 78.21 78 Y mug97...”
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15, SPCC737.04 and SPBC1861.06c.) are found in the S.pombe genome. It is notable that Meu23- and...”

MU132_SCHPO / O13699 Meiotically up-regulated gene 132 protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPAC11G7.06c S. pombe specific UPF0300 family protein 3 from Schizosaccharomyces pombe
Aligns to 152:363 / 430 (49.3%), covers 99.5% of PF08594, 278.0 bits

• function: Has a role in meiosis.
• A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
  Cremona, Molecular biology of the cell 2011
  • “...4 8 14 mug93 SPBC32H8.06 2 TPR repeat protein 4.9 M 5 5 15 mug132 SPAC11G7.06c 0 S. pombe specific UPF0300 family protein 3 60.3 M 5 5 16 mfr1 SPBC1198.12 1 Fizzy-related protein Mfr1 91.8 M 5 5 17 mug97 SPBC146.11c 0 Meiotic chromosome segregation...”
  • “...N 344.85 0.81 425.22 390 N mug125 SPAC1A6.08c N 239.25 0.65 451.15 418 N mug132 SPAC11G7.06c N 224.80 0.48 465.91 434 N meu21 SPAC24C9.07c Y 558.15 0.91 615.04 613 N atg8 SPBP8B7.24c Y 909.20 1.32 688.53 718 N SPBP19A11.02c Y 1480.10 1.89 782.50 847 N mug142...”
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...NLS motif, and five kinds of Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15, SPCC737.04 and SPBC1861.06c.) are found in the S.pombe genome. It is...”

MU133_SCHPO / Q10240 Meiotically up-regulated gene 133 protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPAC4G9.07 S. pombe specific UPF0300 family protein 2 from Schizosaccharomyces pombe
Aligns to 223:434 / 513 (41.3%), covers 99.5% of PF08594, 276.6 bits

• function: Has a role in meiosis.
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...and five kinds of Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15, SPCC737.04 and SPBC1861.06c.) are found in the S.pombe genome. It is notable...”

MU134_SCHPO / O42654 Meiotically up-regulated gene 134 protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPAC10F6.15 S. pombe specific UPF0300 family protein 1 from Schizosaccharomyces pombe
Aligns to 148:357 / 432 (48.6%), covers 99.5% of PF08594, 276.5 bits

• function: Has a role in meiosis.
• A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
  Cremona, Molecular biology of the cell 2011
  • “...M 5 5 17 mug97 SPBC146.11c 0 Meiotic chromosome segregation 185.2 M 5 5 18 SPAC10F6.15 0 S. pombe specific UPF0300 family protein 1 242.8 M 5 5 19 mug137 SPCC1919.11 6 BAR adaptor/SH3 protein 256.2 M 5 5 20 spo3 SPAC607.10 0 Sporulation protein 364.0...”
  • “...pronounced bands are also observed in the cid14 strain for fbp1 , SPAC1610.02c, meu21 , SPAC10F6.15, mug142 , and mde7 ( Figure 4 B, rows 4, 6, 8, 18, 24, and 26). The absence of either Cid14p or Rrp6p leads to increased act1 mRNA levels (...”
• Analysis of DNA strand-specific differential expression with high density tiling microarrays
  Quintales, BMC bioinformatics 2010
  • “...SPBC21C3.19 gene. C) Overexpression of non-annotated dTR100108 and dTR110092. Antisense transcription is also detected across SPAC10F6.15 under conditions of oxidative stress. D) Strong overexpression of antisense RNA (dTR300178) from a 1.5 kb region at the 5' end of the SPCC1919.05 gene. Quantitative data for all differentially...”
• The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe
  Ni, PloS one 2010
  • “...are noticeable exceptions of strand orientation. For instance, the majority of the reads at the SPAC10F6.15 locus were mapped to the Crick strand whereas the annotated transcript is on the Watson strand (Supplementary information file, Figure S6 ), indicating that antisense expression might be dominant for...”
  • “...counts from the top strand (orange) and bottom strand (dark blue) are shown separately. For SPAC10F6.15 locus, the level of antisense transcripts is much higher than that of sense transcripts (open box). (TIF) Click here for additional data file. Figure S7 Dominant antisense expression at the...”
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...and five kinds of Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15, SPCC737.04 and SPBC1861.06c.) are found in the S.pombe genome. It is notable that...”
• Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences
  Vassetzky, Nucleic acids research 1999
  • “...?/? c839 AAACAGGTTAGGGTTATAA 458/1276 SPAC10F6.14c/ SPAC10F6.15 ?/? SPAC10F6 TTCCTGGTTAGGGTTAAAG 1987 SPCC1183.11 ? SPCC1183 D, distance in...”

YJ14_SCHPO / O94245 UPF0300 protein C737.04 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
SPCC737.04 S. pombe specific UPF0300 family protein 6 from Schizosaccharomyces pombe
Aligns to 154:368 / 421 (51.1%), covers 99.1% of PF08594, 255.0 bits

• Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast
  Sanchez, microPublication biology 2023
  • “...DNA damage-responsive protein -1.17 SPCC794.01c gcd1 glucose dehydrogenase -1.13 SPBPB8B6.04c grt1 DNA-binding transcription factor -1.09 SPCC737.04 UPF0300 family protein 6 -1.08 SPBC839.15c tef103 translation elongation factor EF-1 alpha -1.08 SPAC22A12.17c short chain dehydrogenase -1.07 SPAC26H5.09c oxidoreductase in NADPH regeneration -1.07 SPBC24C6.09c phosphoketolase family protein -1.07 SPAC23A1.10...”
• Repression of a large number of genes requires interplay between homologous recombination and HIRA
  Misova, Nucleic acids research 2021
  • “...( SPCC965.11c , SPCC663.06c , SPAC3G9.11c , SPBC947.05c , SPAC11D3.01c , SPAC869.07c , SPAC27D7.09c and SPCC737.04 ) compared with any of the single mutants (Figure 4C ). In addition, at three loci ( SPAC15E1.02c, SPBPB21E7.07 and SPAC212.08c ) the double mutant showed the transcript levels similar...”
  • “...showed additive increase in the transcript levels at three measured loci ( SPCC663.06c, SPBPB21E7.07 and SPCC737.04 ) compared with any of the single mutants (Figure 4D ). Moreover, at four loci ( SPBC16E9.16c , SPCC965.11c , SPAC11D3.01c and SPAC212.08c ), the transcript levels in dbl2clr61 resembled...”
• Role for cohesin in the formation of a heterochromatic domain at fission yeast subtelomeres
  Dheur, Molecular and cellular biology 2011
  • “...SPAC186.01 SPMIT.04 SPAC27D7.09c SPMIT.05 SPAC750.07c SPMIT.10 SPCC737.04 SPMIT.11 Fold change Name VOL. 31, 2011 COHESIN AND SUBTELOMERIC HETEROCHROMATIN...”
• Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation
  Nugent, BMC genomics 2010
  • “...SPBC8E4.05c 1.99 1.54E-08 SPAC32A11.02c 2.65 4.69E-09 frp1 3.69 3.37E-05 SPAC637.03 2.03 0.000132799 SPBC2G2.17c 2.66 2.11E-07 SPCC737.04 3.85 3.10E-07 SPBC4C3.08 2.04 6.23E-08 SPAC56F8.15 2.68 0.001276426 SPBC359.06 3.91 0.000499938 meu10 2.05 4.69E-07 SPAPJ691.02 2.72 1.52E-05 apc10 3.96 4.49E-12 SPCC1840.12 2.05 4.17E-06 SPBC1773.06c 2.76 0.000469242 SPAPB8E5.10 3.98 1.31E-12 SPBPB2B2.02...”
• Global expression changes resulting from loss of telomeric DNA in fission yeast
  Mandell, Genome biology 2005
  • “...SPBC725.06c Signal transduction* SPAC27D7.10c Unknown/hypothetical hsp16 + Stress response SPBC725.10 Unknown/hypothetical cta1 + Stress response SPCC737.04 Unknown/hypothetical gst2 + Stress (sulfur metabolism) SPAC27D7.09c Unknown/hypothetical SPAC4H3.08 Stress response (lipid metabolism)* SPBC725.03 Unknown/hypothetical Fifty-four genes with maintained expression changes twofold or more in both of strains C1 and...”
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...kinds of Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15, SPCC737.04 and SPBC1861.06c.) are found in the S.pombe genome. It is notable that Meu23-...”

SPCC1259.14c S. pombe specific UPF0300 family protein 5 from Schizosaccharomyces pombe
Aligns to 500:710 / 736 (28.7%), covers 99.1% of PF08594, 233.2 bits

• Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells
  Brault, G3 (Bethesda, Md.) 2016
  • “...pvg5 + PvGal biosynthesis protein Pvg5 2.094 2.205 665 a , 267 a , 9 SPCC1259.14c meu27 + UPF0300 family protein 5 2.054 2.557 465 a , 426 a SPBC19F8.06c meu22 + Amino acid transmembrane transporter, predicted Meu22 2.004 2.641 826 a , 724, 118 Noncoding...”
• A novel histone deacetylase complex in the control of transcription and genome stability
  Zilio, Molecular and cellular biology 2014
  • “...SPBC1D7.04 Multiple SPBC28F2.11 SPAPB8E5.09 SPCC1682.16 SPBC660.11 SPCC576.10c SPCC1259.14c SPBC23G7.12c SPBC106.13 5211 2942 2319 1916 1747 1628 1020 674 631...”
• A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
  Cremona, Molecular biology of the cell 2011
  • “...M 5 5 20 spo3 SPAC607.10 0 Sporulation protein 364.0 M 5 5 21 meu27 SPCC1259.14c 0 S. pombe specific UPF0300 family protein 5 120.3 M 5 5 22 spo6 SPBC1778.04 3 Spo4-Spo6 kinase complex regulatory subunit 447.8 M 5 5 23 mpf1 SPAC4G9.05 2 Meiotic...”
• Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe
  Watanabe, Nucleic acids research 2001
  • “...genome. meu27+ encodes a protein identical to SPCC1259.14c with one NLS motif, and five kinds of Meu27-like proteins (SPAC11G7.06c, SPAC4G9.07, SPAC10F6.15,...”

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