Family Search for PF10224 (DUF2205)
PF10224 hits 9 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
AFUA_2G03280, Afu2g03280 bZIP transcription factor, putative from Aspergillus fumigatus Af293
Aligns to 34:111 / 117 (66.7%), covers 98.7% of PF10224, 119.6 bits
- Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus
Liu, mBio 2021 - “...transcription factor (CrrA) + + + + + + + +/ + + + 1F4 AFUA_2G03280 bZIP transcription factor (ZipD) + + + 1G9 AFUA_2G10550 C 2 H 2 transcription factor (FfmA) 2C5 AFUA_3G08520 SRF-type transcription factor (RlmA) + + + +/ 2C7 AFUA_3G08010 C 2...”
- Phosphoproteomics of Aspergillus fumigatus Exposed to the Antifungal Drug Caspofungin
Mattos, mSphere 2020 - “...that undergoes activation in response to alkaline pH) ( 31 ), and a zipD mutant (AFUA_2G03280, encoding a TF important for calcium metabolism and osmotic response) ( 9 , 10 ), were previously found to have reduced CPE. TABLE3 Transcription factors with modulation of phosphorylation Gene...”
- “...AFUA_3G02340 ncb2 b CBF/NF-Y family transcription factor, putative AFUA_2G14720 hapB CCAAT-binding transcription factor subunit HAPB AFUA_2G03280 zipD BZIP transcription factor, putative AFUA_2G01900 rtf1p RNA polymerase II transcription elongation factor Rtf1p, putative AFUA_1G12332 rph1 b Jumonji family transcription factor, putative AFUA_2G13380 areB GATA transcription factor (AreB), putative...”
- Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance
de, PLoS genetics 2019 - “...[Afu1g10550, Afu5g10620, Afu6g12522 ( skn7 ), Afu4g07090, Afu7g03910 ( nsdC ), and as previously described Afu2g03280 ( zipD ) Afu1g06900 ( crzA )] [ 26 32 ], while two mutants showed increased tolerance [Afu1g13190 and Afu3g08010 ( ace1 )] ( Fig 1A ). The calcium-dependent phosphatase...”
- “...at 8.0 g/ml ( Fig 1C ). The null mutants corresponding to the genes Afu1g10550, Afu2g03280 ( zipD ), Afu5g10620, Afu6g12522 ( skn7 ), and Afu4g07090 were more sensitive than the wild-type strain to caspofungin at 1.0 g/ml and exhibited a reduction in the CPE at...”
- The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect
Ries, mBio 2017 - “...Previously, four TFs encoded by the genes htfA (Afu4g10110), zfpA (Afu8g05010), zfpB (Afu1g10230), and zipD (Afu2g03280) were found to be upregulated in the presence of calcium ( 27 , 28 ). Deletion of only zipD resulted in a reduced CPE and increased sensitivity to high levels...”
PTRG_04454 DUF2205 domain containing protein from Pyrenophora tritici-repentis
Aligns to 88:162 / 175 (42.9%), covers 97.3% of PF10224, 118.9 bits
- Characterization of Alternaria infectoria extracellular vesicles
Silva, Medical mycology 2014 - “...response PTRT_04280 | PTRG_04280 | Pyrenophora tritici-repentis predicted protein (207 aa) 23715 Unknown PTRT_04454 | PTRG_04454 | Pyrenophora tritici-repentis conserved hypothetical protein (176 aa) 19309 Predicted coiled-coil protein PTRT_11337 | PTRG_11337 | Pyrenophora tritici-repentis hypothetical protein (527 aa) 61409 Unknown * For protein identification, we searched...”
ANIA_04502 hypothetical protein from Aspergillus nidulans FGSC A4
C8V8D1 BZIP transcription factor, putative (AFU_orthologue AFUA_2G03280) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Aligns to 85:166 / 166 (49.4%), covers 93.3% of PF10224, 113.1 bits
CG5934 uncharacterized protein from Drosophila melanogaster
Aligns to 56:129 / 135 (54.8%), covers 92.0% of PF10224, 98.5 bits
- <i>Drosophila melanogaster</i> Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation
Crain, Genes & development 2024 - “...kb, including seven genes in addition to l(3)mbt : woc , mrt , TfIIA-L , CG5934 , CG5938 , CG14260 , and CG14262. We found minimal differences in the transcriptomes of l(3)mbt GM76 versus a +/ Df , suggesting that the effect that we observed in...”
- Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids
Cinege, Journal of innate immunity 2022 - “...Trs31, Trs20, CG10344, Cam, Arl2, Rab39, CG15168, CG43322, Lerp, Clc, Gos28, Dab, comm, brn, Tomosyn, CG5934, zetaCOP, Arf102F, CG33116, Fer1HCH, Rab2, Trs23, CG7536, CG16865, ATP6AP2, Ykt6, vib, Nhe1, Sec10, Syx16, Doa, ksh, CG15099, Fer2LCH, Snx1, Zip99C, Rab11, Ccm3, CG5021, COX4, Efr, pod1, Rab1, Sec6, park, Bet3,...”
Q5RJZ6 Short coiled-coil protein from Rattus norvegicus
Aligns to 42:117 / 122 (62.3%), covers 86.7% of PF10224, 93.5 bits
- Dynamic changes of serum protein in rats with acute intoxication of Chinese cobra snake venom by proteomic analysis.
Yan, Forensic sciences research 2017 - “...1.432 1.993 1.835 34 900 P39069 Adenylate kinase isoenzyme 1 1.443 1.379 1.383 21 600 Q5RJZ6 Short coiled-coil protein 1.511 3.407 3.010 13 700 P04466 Myosin regulatory light chain 2, skeletal muscle isoform 1.581 1.743 2.639 19 000 P01946 Haemoglobin subunit -1/2 1.600 1.729 1.734 15...”
- “...phosphatase 1J 2.597 1.902 2.141 55 200 P13413 Troponin I 3.090 3.427 2.720 21 700 Q5RJZ6 Short coiled-coil protein 3.392 3.969 2.752 13 700 Q64428 Trifunctional enzyme subunit , mitochondrial 3.449 2.514 2.815 82 600 P19234 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 3.597 4.447 5.986 27...”
NP_115936 short coiled-coil protein isoform 4 from Homo sapiens
Aligns to 42:117 / 122 (62.3%), covers 86.7% of PF10224, 93.5 bits
- Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
Wirth, Journal of molecular biology 2021 - GeneRIF: Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
- Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.
Stringer, Translational psychiatry 2016 - GeneRIF: SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis]
- Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.
Behrens, PloS one 2013 - GeneRIF: SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction.
- Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO).
Alborghetti, PloS one 2013 - GeneRIF: Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process.
- Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.
McKnight, The EMBO journal 2012 - GeneRIF: The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation.
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose, Molecular medicine (Cambridge, Mass.) - GeneRIF: Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
SCOC_HUMAN / Q9UIL1 Short coiled-coil protein from Homo sapiens (Human) (see 3 papers)
Aligns to 79:154 / 159 (47.8%), covers 86.7% of PF10224, 92.4 bits
- function: Positive regulator of amino acid starvation-induced autophagy.
subunit: Homodimer (PubMed:24098481). Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1. Interacts with NRBF2 (PubMed:22354037). - The Eutopic Endometrium Proteome in Endometriosis Reveals Candidate Markers and Molecular Mechanisms of Physiopathology
Méar, Diagnostics (Basel, Switzerland) 2022 - “...Q9P2M7 Cingulin CGN up up - O95210 Starch-binding domain-containing protein 1 STBD1 up up - Q9UIL1 Short coiled-coil protein SCOC up up - O00292 Left-right determination factor 2 LEFTY2 up up - P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 up up - P22748 Carbonic anhydrase...”
- Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
Wirth, Journal of molecular biology 2021 - “...mammalian ATG8 proteins through a N-terminal LIR domain. A. Sequence alignment of SCOC isoform 1 (Q9UIL1), SCOC isoform 4 (Q9UIL1-4), SCOC isoform 3 (Q9UIL1-3), SCOC isoform 2 (Q9UIL1-2), SCOC isoform 5 (A0A0C4DGB0/protein accession AAK01707) using the Clustal Omega program of the UniProt database ( www.uniprot.org )....”
- “...The UniProt database numbers ( https://www.uniprot.org/ ) of the SCOC isoforms are: SCOC isoform 1 (Q9UIL1), SCOC isoform 4 (Q9UIL1-4), SCOC isoform 3 (Q9UIL1-3), SCOC isoform 2 (Q9UIL1-2), SCOC isoform 5 (A0A0C4DGB0/protein accession AAK01707). Atomic coordinates and crystallographic structure factors have been deposited in the Protein...”
- Exploring the Key Genes and Identification of Potential Diagnosis Biomarkers in Alzheimer's Disease Using Bioinformatics Analysis.
Yu, Frontiers in aging neuroscience 2021 - “...type IV CAMK4 O95206 Protocadherin-8 PCDH8 P61088 Ubiquitin-conjugating enzyme E2 N UBE2N O43768 Alpha-endosulfine ENSA Q9UIL1 Short coiled-coil protein SCOC Q13530 Serine incorporator 3 SERINC3 Q9Y5V3 Melanoma-associated antigen D 1 MAGED1 Q96F83 Clathrin-binding box of aftiphilin-containing protein 1 C14orf79 P80723 Brain acid soluble protein 1 BASP1...”
- Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation
Behrens, PloS one 2013 - “...essential for this interaction. Materials and Methods Purification and crystallization of SCOC SCOC(78-159) (SwissProt entry Q9UIL1 isoform1) was cloned in pET28a (Novagen) using NcoI and XhoI cleavage sites. A synthetic gene (Mr Gene) optimized for E. coli expression was used as a template for PCR. The...”
- Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike.
Wejda, The Journal of biological chemistry 2012
Gm16500 short coiled-coil protein-like from Mus musculus
Aligns to 82:157 / 162 (46.9%), covers 85.3% of PF10224, 89.7 bits
- Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor
Haugg, FEBS open bio 2022 - “...protein 2 homolog ( Grhl2 ), adipolin ( C1qtnf12 ), and short coiledcoil proteinlike ( Gm16500 ), while egl nine homolog 1 ( Egln1 ) was downregulated. Table 3 Most extremely regulated genes. All genes with padj<0.05 and |log2(FC)|>2.0 for both pairwise group comparisons are listed....”
- “...protein 3like 0.018 2.4 Grhl2 Grainyheadlike protein 2 homolog <0.001 2.1 C1qtnf12 Adipolin <0.001 2.1 Gm16500 Short coiledcoil proteinlike <0.001 2.0 Egln1 Egl nine homolog 1 John Wiley & Sons, Ltd Indicator genes Among the indicator genes, thyroxine 5deiodinase ( Dio3 ) and period circadian protein...”
SLO1_YEAST / Q3E784 SCOCO-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
YER180C-A Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO from Saccharomyces cerevisiae
Aligns to 12:85 / 85 (87.1%), covers 77.3% of PF10224, 35.8 bits
- subunit: Interacts with ARL3.
- SCRaMbLE generates evolved yeasts with increased alkali tolerance
Ma, Microbial cell factories 2019 - “...yML098 revealed five deletions (YEL060C, an intergenic sequence between YER032W and YEL033C, YER161C-YER164W, YER175C-YER176W, and YER180C-A). Figure S8. Sequencing depth of synthetic chromosome V in yML099. Deep sequencing coverage of yML099 revealed three deletions (YER091C-YER092W, YER134C-YER135C, YER161C-YER164W) and one duplication (YER132C-YER133W). Figure S9. Sequencing depth of...”
- Precise control of SCRaMbLE in synthetic haploid and diploid yeast
Jia, Nature communications 2018 - “...in yJBH012 and the YEL016C-YEL013W deletion was observed in yJBH026. Two deletions ( YEL016C-YEL013W and YER180C-A ) were observed in yJBH027. Long-read sequencing analysis of synV in yJBH001 showed the same two deletions without any inversions or translocations (Supplementary Fig. 9 ). Interestingly, a common deletion...”
- Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii
Brachat, Genome biology 2003 - “...x AER271W 81 YCR075W-A/YNR034W-A 75/99 44.00/46.15 x ACL158W 95 YDL160C-A 80 55.70 x AGR097W-A 66 YER180C-A 85 83.70 x AFR298C 73 YIL156W-B 73 71.23 x x x AFL216C 49 YJL127C-B 52 61.22 x x AAL130W 93 YJR005C-A/YGR169C-A 92/93 74.44/50.82 x x ABR148C-A 117 YJR112W-A 109 56.44...”
Or search for genetic data about PF10224 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory