Family Search for PF10224 (DUF2205)
PF10224 hits 10 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
AFUA_2G03280, Afu2g03280 bZIP transcription factor, putative from Aspergillus fumigatus Af293
Aligns to 34:111 / 117 (66.7%), covers 98.7% of PF10224, 119.6 bits
- Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus
Liu, mBio 2021 - “...transcription factor (CrrA) + + + + + + + +/ + + + 1F4 AFUA_2G03280 bZIP transcription factor (ZipD) + + + 1G9 AFUA_2G10550 C 2 H 2 transcription factor (FfmA) 2C5 AFUA_3G08520 SRF-type transcription factor (RlmA) + + + +/ 2C7 AFUA_3G08010 C 2...”
- Phosphoproteomics of Aspergillus fumigatus Exposed to the Antifungal Drug Caspofungin
Mattos, mSphere 2020 - “...that undergoes activation in response to alkaline pH) ( 31 ), and a zipD mutant (AFUA_2G03280, encoding a TF important for calcium metabolism and osmotic response) ( 9 , 10 ), were previously found to have reduced CPE. TABLE3 Transcription factors with modulation of phosphorylation Gene...”
- “...AFUA_3G02340 ncb2 b CBF/NF-Y family transcription factor, putative AFUA_2G14720 hapB CCAAT-binding transcription factor subunit HAPB AFUA_2G03280 zipD BZIP transcription factor, putative AFUA_2G01900 rtf1p RNA polymerase II transcription elongation factor Rtf1p, putative AFUA_1G12332 rph1 b Jumonji family transcription factor, putative AFUA_2G13380 areB GATA transcription factor (AreB), putative...”
- Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance
de, PLoS genetics 2019 - “...[Afu1g10550, Afu5g10620, Afu6g12522 ( skn7 ), Afu4g07090, Afu7g03910 ( nsdC ), and as previously described Afu2g03280 ( zipD ) Afu1g06900 ( crzA )] [ 26 32 ], while two mutants showed increased tolerance [Afu1g13190 and Afu3g08010 ( ace1 )] ( Fig 1A ). The calcium-dependent phosphatase...”
- “...at 8.0 g/ml ( Fig 1C ). The null mutants corresponding to the genes Afu1g10550, Afu2g03280 ( zipD ), Afu5g10620, Afu6g12522 ( skn7 ), and Afu4g07090 were more sensitive than the wild-type strain to caspofungin at 1.0 g/ml and exhibited a reduction in the CPE at...”
- The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect
Ries, mBio 2017 - “...Previously, four TFs encoded by the genes htfA (Afu4g10110), zfpA (Afu8g05010), zfpB (Afu1g10230), and zipD (Afu2g03280) were found to be upregulated in the presence of calcium ( 27 , 28 ). Deletion of only zipD resulted in a reduced CPE and increased sensitivity to high levels...”
PTRG_04454 DUF2205 domain containing protein from Pyrenophora tritici-repentis
Aligns to 88:162 / 175 (42.9%), covers 97.3% of PF10224, 118.9 bits
- Characterization of Alternaria infectoria extracellular vesicles
Silva, Medical mycology 2014 - “...response PTRT_04280 | PTRG_04280 | Pyrenophora tritici-repentis predicted protein (207 aa) 23715 Unknown PTRT_04454 | PTRG_04454 | Pyrenophora tritici-repentis conserved hypothetical protein (176 aa) 19309 Predicted coiled-coil protein PTRT_11337 | PTRG_11337 | Pyrenophora tritici-repentis hypothetical protein (527 aa) 61409 Unknown * For protein identification, we searched...”
C8V8D1 BZIP transcription factor, putative (AFU_orthologue AFUA_2G03280) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
ANIA_04502 hypothetical protein from Aspergillus nidulans FGSC A4
Aligns to 85:166 / 166 (49.4%), covers 93.3% of PF10224, 113.1 bits
CG5934 uncharacterized protein from Drosophila melanogaster
Aligns to 56:129 / 135 (54.8%), covers 92.0% of PF10224, 98.5 bits
- Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids
Cinege, Journal of innate immunity 2022 - “...Trs31, Trs20, CG10344, Cam, Arl2, Rab39, CG15168, CG43322, Lerp, Clc, Gos28, Dab, comm, brn, Tomosyn, CG5934, zetaCOP, Arf102F, CG33116, Fer1HCH, Rab2, Trs23, CG7536, CG16865, ATP6AP2, Ykt6, vib, Nhe1, Sec10, Syx16, Doa, ksh, CG15099, Fer2LCH, Snx1, Zip99C, Rab11, Ccm3, CG5021, COX4, Efr, pod1, Rab1, Sec6, park, Bet3,...”
Q5RJZ6 Short coiled-coil protein from Rattus norvegicus
Aligns to 42:117 / 122 (62.3%), covers 86.7% of PF10224, 93.5 bits
- Dynamic changes of serum protein in rats with acute intoxication of Chinese cobra snake venom by proteomic analysis.
Yan, Forensic sciences research 2017 - “...1.432 1.993 1.835 34 900 P39069 Adenylate kinase isoenzyme 1 1.443 1.379 1.383 21 600 Q5RJZ6 Short coiled-coil protein 1.511 3.407 3.010 13 700 P04466 Myosin regulatory light chain 2, skeletal muscle isoform 1.581 1.743 2.639 19 000 P01946 Haemoglobin subunit -1/2 1.600 1.729 1.734 15...”
- “...phosphatase 1J 2.597 1.902 2.141 55 200 P13413 Troponin I 3.090 3.427 2.720 21 700 Q5RJZ6 Short coiled-coil protein 3.392 3.969 2.752 13 700 Q64428 Trifunctional enzyme subunit , mitochondrial 3.449 2.514 2.815 82 600 P19234 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 3.597 4.447 5.986 27...”
NP_115936 short coiled-coil protein isoform 4 from Homo sapiens
Aligns to 42:117 / 122 (62.3%), covers 86.7% of PF10224, 93.5 bits
- Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
Wirth, Journal of molecular biology 2021 - GeneRIF: Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
- Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.
Stringer, Translational psychiatry 2016 - GeneRIF: SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis]
- Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.
Behrens, PloS one 2013 - GeneRIF: SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction.
- Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO).
Alborghetti, PloS one 2013 - GeneRIF: Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process.
- Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.
McKnight, The EMBO journal 2012 - GeneRIF: The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation.
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose, Molecular medicine (Cambridge, Mass.) - GeneRIF: Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
SCOC_HUMAN / Q9UIL1 Short coiled-coil protein from Homo sapiens (Human) (see 3 papers)
Aligns to 79:154 / 159 (47.8%), covers 86.7% of PF10224, 92.4 bits
- function: Positive regulator of amino acid starvation-induced autophagy.
subunit: Homodimer (PubMed:24098481). Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1. Interacts with NRBF2 (PubMed:22354037). - The Eutopic Endometrium Proteome in Endometriosis Reveals Candidate Markers and Molecular Mechanisms of Physiopathology
Méar, Diagnostics (Basel, Switzerland) 2022 - “...Q9P2M7 Cingulin CGN up up - O95210 Starch-binding domain-containing protein 1 STBD1 up up - Q9UIL1 Short coiled-coil protein SCOC up up - O00292 Left-right determination factor 2 LEFTY2 up up - P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 up up - P22748 Carbonic anhydrase...”
- Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
Wirth, Journal of molecular biology 2021 - “...mammalian ATG8 proteins through a N-terminal LIR domain. A. Sequence alignment of SCOC isoform 1 (Q9UIL1), SCOC isoform 4 (Q9UIL1-4), SCOC isoform 3 (Q9UIL1-3), SCOC isoform 2 (Q9UIL1-2), SCOC isoform 5 (A0A0C4DGB0/protein accession AAK01707) using the Clustal Omega program of the UniProt database ( www.uniprot.org )....”
- “...The UniProt database numbers ( https://www.uniprot.org/ ) of the SCOC isoforms are: SCOC isoform 1 (Q9UIL1), SCOC isoform 4 (Q9UIL1-4), SCOC isoform 3 (Q9UIL1-3), SCOC isoform 2 (Q9UIL1-2), SCOC isoform 5 (A0A0C4DGB0/protein accession AAK01707). Atomic coordinates and crystallographic structure factors have been deposited in the Protein...”
- Exploring the Key Genes and Identification of Potential Diagnosis Biomarkers in Alzheimer's Disease Using Bioinformatics Analysis.
Yu, Frontiers in aging neuroscience 2021 - “...type IV CAMK4 O95206 Protocadherin-8 PCDH8 P61088 Ubiquitin-conjugating enzyme E2 N UBE2N O43768 Alpha-endosulfine ENSA Q9UIL1 Short coiled-coil protein SCOC Q13530 Serine incorporator 3 SERINC3 Q9Y5V3 Melanoma-associated antigen D 1 MAGED1 Q96F83 Clathrin-binding box of aftiphilin-containing protein 1 C14orf79 P80723 Brain acid soluble protein 1 BASP1...”
- Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation
Behrens, PloS one 2013 - “...essential for this interaction. Materials and Methods Purification and crystallization of SCOC SCOC(78-159) (SwissProt entry Q9UIL1 isoform1) was cloned in pET28a (Novagen) using NcoI and XhoI cleavage sites. A synthetic gene (Mr Gene) optimized for E. coli expression was used as a template for PCR. The...”
- Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike.
Wejda, The Journal of biological chemistry 2012
Gm16500 short coiled-coil protein-like from Mus musculus
Aligns to 82:157 / 162 (46.9%), covers 85.3% of PF10224, 89.7 bits
- Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor
Haugg, FEBS open bio 2022 - “...protein 2 homolog ( Grhl2 ), adipolin ( C1qtnf12 ), and short coiledcoil proteinlike ( Gm16500 ), while egl nine homolog 1 ( Egln1 ) was downregulated. Table 3 Most extremely regulated genes. All genes with padj<0.05 and |log2(FC)|>2.0 for both pairwise group comparisons are listed....”
- “...protein 3like 0.018 2.4 Grhl2 Grainyheadlike protein 2 homolog <0.001 2.1 C1qtnf12 Adipolin <0.001 2.1 Gm16500 Short coiledcoil proteinlike <0.001 2.0 Egln1 Egl nine homolog 1 John Wiley & Sons, Ltd Indicator genes Among the indicator genes, thyroxine 5deiodinase ( Dio3 ) and period circadian protein...”
UMAG_10929 uncharacterized protein from Ustilago maydis 521
Aligns to 26:94 / 96 (71.9%), covers 73.3% of PF10224, 39.9 bits
- Construction and analysis of gene co-expression network in the pathogenic fungus Ustilago maydis
Soberanes-Gutiérrez, Frontiers in microbiology 2022 - “...). Finally, in Sienna3, Brown, Cyan, and Magenta the hubs are UMAG_04807, UMAG_03644, UMAG_05198, and UMAG_10929, respectively, which code for hypothetical proteins ( Table 2 ). Table 2 Hub genes and their encoding proteins in the GCN modules of U. maydis . Module Hub gene (...”
- “...(32) putative 20S proteasome subunit beta 7 Darkred UMAG_00105 (28) Iron transport multicopper oxidase Magenta UMAG_10929 (35) Hypothetical protein Darkmagenta UMAG_10135 (39) Related to MCM10 - essential chromatin-associated protein involved in the initiation of DNA replication UMAG_01008 (39) Putative DNA polymerase epsilon, catalytic subunit A Cyan...”
SLO1_YEAST / Q3E784 SCOCO-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
YER180C-A Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO from Saccharomyces cerevisiae
Aligns to 12:85 / 85 (87.1%), covers 77.3% of PF10224, 35.8 bits
- subunit: Interacts with ARL3.
- SCRaMbLE generates evolved yeasts with increased alkali tolerance
Ma, Microbial cell factories 2019 - “...yML098 revealed five deletions (YEL060C, an intergenic sequence between YER032W and YEL033C, YER161C-YER164W, YER175C-YER176W, and YER180C-A). Figure S8. Sequencing depth of synthetic chromosome V in yML099. Deep sequencing coverage of yML099 revealed three deletions (YER091C-YER092W, YER134C-YER135C, YER161C-YER164W) and one duplication (YER132C-YER133W). Figure S9. Sequencing depth of...”
- Precise control of SCRaMbLE in synthetic haploid and diploid yeast
Jia, Nature communications 2018 - “...in yJBH012 and the YEL016C-YEL013W deletion was observed in yJBH026. Two deletions ( YEL016C-YEL013W and YER180C-A ) were observed in yJBH027. Long-read sequencing analysis of synV in yJBH001 showed the same two deletions without any inversions or translocations (Supplementary Fig. 9 ). Interestingly, a common deletion...”
- Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii
Brachat, Genome biology 2003 - “...x AER271W 81 YCR075W-A/YNR034W-A 75/99 44.00/46.15 x ACL158W 95 YDL160C-A 80 55.70 x AGR097W-A 66 YER180C-A 85 83.70 x AFR298C 73 YIL156W-B 73 71.23 x x x AFL216C 49 YJL127C-B 52 61.22 x x AAL130W 93 YJR005C-A/YGR169C-A 92/93 74.44/50.82 x x ABR148C-A 117 YJR112W-A 109 56.44...”
Or search for genetic data about PF10224 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory