Family Search for PF10233 (Cg6151-P)
PF10233 hits 12 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
PADG_11110 golgi apparatus membrane protein TVP18 from Paracoccidioides brasiliensis Pb18
Aligns to 19:129 / 147 (75.5%), covers 100.0% of PF10233, 143.5 bits
TVP18_YEAST / Q04767 Golgi apparatus membrane protein TVP18; TLG2 compartment vesicle protein of 18 kDa from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
NP_013787 Tvp18p from Saccharomyces cerevisiae S288C
A6ZMD0 Golgi apparatus membrane protein TVP18 from Saccharomyces cerevisiae (strain YJM789)
YMR071C Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments from Saccharomyces cerevisiae
Aligns to 30:141 / 167 (67.1%), covers 100.0% of PF10233, 134.8 bits
- function: Golgi membrane protein involved in vesicular trafficking.
subunit: Interacts with TVP15 and YIP4. - Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2-containing Golgi/endosome compartments of Saccharomyces cerevisiae.
Inadome, Experimental cell research 2007 (PubMed)- GeneRIF: Tvp proteins collectively assist in the effective maintenance/function of the late Golgi/endosomal compartments.
- PalmPred: an SVM based palmitoylation prediction method using sequence profile information.
Kumari, PloS one 2014 - “...in the text. Protein Uniprot ID Uniprot annotation Experimentally identified sites IFS-Palm WAP-Palm PalmPred TVP18 A6ZMD0 78 HIP1 P06775 603 339, 463 339 RHO2 P06781 188* 188 188 188 NUC1 P08466 TUB1 P09733 14 GPA2 P10823 4 4 4 GAP1 P19145 286 YCK1 P23291 537 #...”
- CSS-Palm 2.0: an updated software for palmitoylation sites prediction
Ren, Protein engineering, design & selection : PEDS 2008 - “...P48525 P08466 P32867 P39926 Q12241 Q08144 P50108 P46985 A6ZMD0 Q06170 Amino acid permeases (AAPs) Agp1 P25376 Bap2 P38084 Gap1 P19145 Gnp1 P48813 Hip1 P06775...”
- Widespread Cumulative Influence of Small Effect Size Mutations on Yeast Quantitative Traits
Hua, Cell systems 2018 - “...YGR247W, YFL004W, YBR023C, YIL044C, YMR052W, YDL204W, YBR067C, YDR153C, YIL043C, YNL095C, YDR476C, YOR307C, YOR321W, YCR011C, YMR237W, YMR071C, YER004W, YPR028W, YGL255W, YPL170W, YKL063C, YJL044C, YLR023C, YMR215W, YMR251W-A, YGR261C, YPR091C, YDR056C, YLL028W, YLR330W, YBL010C, YNR019W, YGL124C, YDR294C, YNL046W, YDR519W, YKR088C, YLR042C, YKL094W, YCR048W, YCR043C, YDR084C, YKR067W, YJL196C, YLL061W, YML101C,...”
- Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae
Sullivan, Eukaryotic cell 2009 - “...YDR436w YDL090c YER155c YLR361c YMR323w YDL244w YCL017c YDR051c YMR071c YPL158c YFL040w YKL027w YNR075w YGL083w YHR080c ELF1 YKU80 ADA2 RDN25 RRF1 HOF1 RAS2...”
- A novel pathway that coordinates mitotic exit with spindle position
Nelson, Molecular biology of the cell 2007 - “...yhr033w, yhr198c, yip3, yjl218w, yjr056c, ykl056c, ykl063c, ymr071c, ymr181c, ymr196w, ymr226c, ynl101w, ynl116w, ynl187w, ynl335w, yor033w, and ypl070w. A mild...”
- After the duplication: gene loss and adaptation in Saccharomyces genomes
Cliften, Genetics 2006 - “...YKL001C MET14 YKL154W SRP102 YLR066W SPC3 YML036W YML036W YMR071C YMR071C YMR074C YMR074C YOL108C INO4 YOR327C SNC2 YOR351C MEK1 S. castellii's position as the...”
- A genetic dissection of Aip1p's interactions leads to a model for Aip1p-cofilin cooperative activities
Clark, Molecular biology of the cell 2006 - “...BSP1 YNL138w YNL079c YNL093w YNL106c YGR268c YGR241c YMR071c YER123w YLR429w YHR016c YMR091c YMR092c YHR181w YOL113w YKL129c YMR095c YMR109w YFR024c-A YLR337c...”
- Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method
Xie, Proceedings of the National Academy of Sciences of the United States of America 2005 - “...13 14 Control YOR200W YOR199W YLR288C YNL005C YNR041C YMR071C YOR187W YPR124W YJR104C YMR066W YDL198C YDL181W YMR038C YGR076C YNL135C Gene name MEC3 MRP7 COQ2...”
- Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments
Inadome, Molecular and cellular biology 2005 - “...protein of 26 kDa), the products of YKR088c, YDR084w, YMR071c, and YDR100w found in the Tlg2 compartment as Tvp38, Tvp23, Tvp18, and Tvp15 (Tlg2 compartment...”
- “...H. sapiens Svp26 (Yhr181w) Tvp38 (Ykr088c) Tvp23 (Ydr084w) Tvp18 (Ymr071c) Tvp15 (Ydr100w) Gvp36 (Yil041w) 288 26,283 4 337 38,306 5 199 23,151 3 167 18,692 3...”
TVP18_SCHPO / O74375 Golgi apparatus membrane protein tvp18 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
Aligns to 30:141 / 164 (68.3%), covers 100.0% of PF10233, 123.6 bits
- function: Golgi membrane protein involved in vesicular trafficking.
FLOWR_HUMAN / Q9UGQ2 Calcium channel flower homolog; Calcium channel flower domain-containing protein 1 from Homo sapiens (Human) (see 2 papers)
TC 1.A.55.1.1 / Q9UGQ2 Mammalian Ca2+ channel, Flower, homologue, isoform a from Homo sapiens (see 5 papers)
Aligns to 34:143 / 172 (64.0%), covers 99.1% of PF10233, 104.5 bits
- function: Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling (PubMed:31341286, PubMed:37348560). In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process (PubMed:31341286).
function: [Isoform 1]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:31341286). During cell competition, if levels of this isoform in cells is higher than in the surrounding neighboring cells, the cells are recognized as 'winner' cells, and do not undergo elimination via apoptosis (PubMed:31341286).
function: [Isoform 2]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:31341286). During cell competition, if levels of this isoform in unfit cells is higher than in the surrounding neighboring cells, the cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy 'winner' cell population (PubMed:31341286).
function: [Isoform 3]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:31341286). During cell competition, if levels of this isoform in unfit cells is higher than in the surrounding neighboring cells, the cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy 'winner' cell population (PubMed:31341286).
function: [Isoform 4]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:31341286). During cell competition, if levels of this isoform in cells is higher than in the surrounding neighboring cells, the cells are recognized as 'winner' cells, and do not undergo elimination via apoptosis (PubMed:31341286).
subunit: Interacts with adaptor protein complex 2 (AP-2). - substrates: Ca2+
- Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays.
Khoruddin, Scientific reports 2021 - “...FASTA format was used as the input. UniProtKB accession numbers for the sequences are: CACFD1, Q9UGQ2; RREB1, Q92766; LRRC34, Q8IZ02; ETFA, P13804; CPVL, Q9H3G5; INCENP, Q9NQS7; FARP2, O94887; and TYR, P14679. Consurf created an output consists of the protein sequence and multiple sequence alignment colored by...”
- “...the protein stability of the damaging nsSNPs. UniProtKB accession numbers for the sequences are: CACFD1, Q9UGQ2; RREB1, Q92766; LRRC34, Q8IZ02; ETFA, P13804; CPVL, Q9H3G5; INCENP, Q9NQS7; FARP2, O94887; and TYR, P14679. The output included the indicator of the prediction (increase/decrease) of protein stability based on the...”
FLOWR_MOUSE / Q8BG21 Calcium channel flower homolog; Calcium channel flower domain-containing protein 1 from Mus musculus (Mouse) (see 3 papers)
Aligns to 33:142 / 171 (64.3%), covers 99.1% of PF10233, 103.9 bits
- function: Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling (PubMed:22362363, PubMed:29288152). In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules (CGs) at the immuno synapse (PubMed:29288152). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process (PubMed:22362363).
subunit: Interacts with adaptor protein complex 2 (AP-2).
disruption phenotype: Viable and fertile (PubMed:22362363). Results in lowered susceptibility to skin papillomas induced by 7,12- dimethylbenzanthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) (PubMed:22362363). In cytotoxic T-lymphoocytes, leads to a complete block of early cytotoxic granules (CG) endocytosis at the immuno synapse thereby impairing serial killing of target cells (PubMed:29288152). Does not affect cytotoxic granules exocytosis and global calcium signaling, however increases latency of CG fusion and endosome recycling (PubMed:29288152).
FLOWR_RAT / D4A9I3 Calcium channel flower homolog; Calcium channel flower domain-containing protein 1 from Rattus norvegicus (Rat) (see 2 papers)
NP_001100031 calcium channel flower homolog from Rattus norvegicus
Aligns to 33:142 / 171 (64.3%), covers 99.1% of PF10233, 103.9 bits
- function: Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling (By similarity). In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin-mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (PubMed:28414717). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules (CGs) at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process (By similarity).
subunit: Interacts with adaptor protein complex 2 (AP-2).
disruption phenotype: Knockdown in cultured hippocampal neurons impairs Clathrin-mediated endocytosis (CME) in response to mild stimulation (200 action potentials at 20 Hz) and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (1,600 action potentials delivered at 80 Hz). - A Ca2+ channel differentially regulates Clathrin-mediated and activity-dependent bulk endocytosis.
Yao, PLoS biology 2017 - GeneRIF: The role of Fwe protein isoform 2 in endocytosis in hippocampal neurons
NP_001229298 calcium channel flower homolog isoform c from Homo sapiens
Aligns to 34:143 / 233 (47.2%), covers 99.1% of PF10233, 103.4 bits
TC 1.A.55.1.3 / Q93533 Roundworm Flower homologue (166aas) from Caenorhabditis elegans (see paper)
Aligns to 33:142 / 166 (66.3%), covers 99.1% of PF10233, 96.9 bits
FLOWR_DROME / Q95T12 Calcium channel flower; 3L5 from Drosophila melanogaster (Fruit fly) (see 12 papers)
TC 1.A.55.1.2 / Q95T12 Insect Ca2+ channel, Flower (194 aas; 4 putative TMSs) from Drosophila melanogaster (see 4 papers)
NP_648804 flower, isoform A from Drosophila melanogaster
Aligns to 35:147 / 194 (58.2%), covers 100.0% of PF10233, 91.8 bits
- function: Transmembrane protein which mediates synaptic endocytosis, fitness-based cell culling, neuronal culling, morphogen gradient scaling, and calcium transport (PubMed:20627080, PubMed:23810538, PubMed:25601460, PubMed:28011160, PubMed:33300871, PubMed:35301437). Regulates synaptic endocytosis and hence couples exo- with endocytosis (PubMed:19737521, PubMed:28414717, PubMed:29288152, PubMed:33300871). Controls two major modes of synaptic vesicle (SV) endocytosis in the synaptic boutons of neuromuscular junctions (NMJs); Ca(2+) channel- independent Clathrin-mediated endocytosis (CME) in response to mild stimulation, and Ca(2+) channel-dependent activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (PubMed:28414717, PubMed:33300871). Functions in ADBE and subsequent SV reformation from bulk endosomes by initiating Ca(2+) channel-dependent phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) compartmentalization in synaptic boutons (PubMed:28414717, PubMed:33300871). There it acts at the periactive zone to provide the low Ca(2+) levels required to initiate Calcineurin activation and upregulate PtdIns(4,5)P2 (PubMed:33300871). Conversely PtdIns(4,5)P2 enhances fwe Ca(2+) channel-activity, establishing a positive feedback loop that induces PtdIns(4,5)P2 microdomain at the periactive zone (PubMed:33300871). These microdomains trigger bulk membrane invagination (i.e. ADBE) by triggering actin polymerization while also promoting localization of fwe to bulk endosomes, thereby removing the ADBE trigger to reduce endocytosis and prevent excess membrane uptake (PubMed:33300871). PtdIns(4,5)P2 then promotes SV reformation from the bulk endosomes, to coordinate ADBE and subsequent SV reformation (PubMed:33300871). Different combinations of the flower isoforms at the cell membrane are also required for the identification and elimination of suboptimal or supernumerary cells during development, regeneration, and adulthood (PubMed:20627080, PubMed:20951347, PubMed:23810538, PubMed:25601460, PubMed:28011160, PubMed:30590040). Required for the recognition and elimination of unfit cells in the developing wing during cell competition (PubMed:20627080). Also required for efficient identification and elimination of injured, damaged and/or dysfunctional neurons during regeneration of the adult brain (PubMed:25754635, PubMed:30590040). In the developing pupal retina, mediates the elimination of unwanted postmitotic neurons, including supernumerary photoreceptor neurons that form at the periphery of the retina and are contained within incomplete ommatidia units (PubMed:23810538). Downstream of the flower fitness fingerprints, cells identified as unwanted or unfit are eliminated via apoptosis through the expression of ahuizotl (azot) (PubMed:25601460, PubMed:30590040). However, the cells marked for elimination by the flower isoforms only undergo apoptosis if additional thresholds are met; (1) their neighboring fit/healthy cells express different levels of the fwe isoforms, and (2) the levels of the protective signal SPARC expressed by the loser or unwanted cells are unable to inhibit caspase activation (PubMed:20627080, PubMed:20951347, PubMed:23810538). These additional thresholds for flower-mediated apoptosis, allows useful cells to recover from transient and limited stress before they are unnecessarily eliminated (PubMed:20951347). Functions with dally and magu in a mechanism of scaling, which utilises apoptosis to ensure that the dpp morphogen gradient, which mediates organ growth, remains proportional to the size of the growing wing (PubMed:35301437). In this mechanism, fwe represses dally- and Magu-dependent activity in expanding the gradient, and dally/Magu inhibits fwe-dependent apoptosis to keep cell death rate low (PubMed:35301437). When the levels of these different proteins are optimally regulated the gradient correctly scales with organ growth but when this fails, fwe-mediated apoptosis is activated to trim the developing tissue to match the correct size of the gradient (PubMed:35301437).
function: [Isoform Ubi]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:20627080, PubMed:25601460). In the wing imaginal disk, this isoform is highly expressed in healthy/normal cells but is down- regulated in cells with decreased fitness (PubMed:20627080). During cell competition, if levels of this isoform in unfit cells is lower than in the surrounding neighboring cells, the suboptimal cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy 'winner' cell population (PubMed:20627080).
function: [Isoform Lose-A]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit or fit cells during cell selection processes in order to maintain tissue health (PubMed:20627080, PubMed:25601460). In the wing imaginal disk, this isoform displays low levels of expression in healthy/normal cells but is up-regulated in cells with decreased fitness (PubMed:20627080, PubMed:25601460). During cell competition, if levels of this isoform in unfit cells is higher than in the surrounding neighboring cells, the suboptimal cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy 'winner' cell population (PubMed:20627080, PubMed:25601460).
function: [Isoform Lose-B]: Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit cells for cell selection processes during development, regeneration, and to maintain tissue health (PubMed:20627080, PubMed:25601460, PubMed:25754635, PubMed:30590040). During cell competition in certain tissues, marks suboptimal or damaged cells as 'loser' cells (PubMed:20627080, PubMed:25601460, PubMed:25754635, PubMed:30590040). In cells of the wing imaginal disk and damaged or dysfunctional neurons in the adult optic lobe, this isoform displays low to no expression in healthy/normal cells but is up-regulated in cells with decreased fitness or damage-affected neurons (PubMed:20627080, PubMed:25754635, PubMed:30590040). During cell competition, if levels of this isoform in unfit cells is higher than in the surrounding neighboring cells, the suboptimal cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy/undamaged 'winner' cell population (PubMed:20627080, PubMed:25754635, PubMed:30590040). In the developing pupal retina, also required for the recognition and elimination of postmitotic neurons, including supernumerary photoreceptor neurons that form at the periphery of the retina and are contained within incomplete ommatidia units (PubMed:23810538). Activity at the peripheral retina is induced by the wg signaling pathway but, once activated, it promotes apoptosis of supernumerary photoreceptor neurons independently of wg signaling and snail function (PubMed:23810538).
subunit: [Isoform Ubi]: Associates with the dally/ magu complex.
subunit: [Isoform Lose-A]: Homomultimer (PubMed:19737521). Associates with the dally/ magu complex (PubMed:35301437).
subunit: [Isoform Lose-B]: Associates with the dally/ magu complex.
disruption phenotype: Lethal; mutants die either during the embryonic stage or the first instar larval stage (PubMed:28011160). Embryos frequently display head involution defects, some do not develop a cuticle and/or occasionally display dorsal closure defects (PubMed:28011160). The nervous system of embryos also displays developmental defects (PubMed:19737521, PubMed:20627080). In presynaptic terminals, intracellular resting calcium levels and endocytosis is impaired, whereas exocytosis is normal (PubMed:19737521). Boutons at the neuromuscular junctions exhibit a significant depletion in the number of synaptic vesicles (PubMed:19737521). There are numerous extra boutons which are often small, clustered, and flowery in nature (PubMed:19737521). Mutant nerve terminals display omega structures and collared pits (PubMed:19737521). RNAi-mediated knockdown in wing disks reduces cell apoptosis during Myc-mediated cell competition experiments (PubMed:28011160, PubMed:35301437). RNAi-mediated knockdown in the posterior compartment of the wing disk, has no effect on tissue growth under normal conditions however, growth is reduced in tissues undergoing Myc- mediated cell competition (PubMed:20627080). RNAi-mediated knockdown during Myc-mediated cell competition experiments, has no effect on up- regulation of SPARC in loser cells (PubMed:20951347).
disruption phenotype: [Isoform Ubi]: RNAi-mediated knockdown in the posterior compartment of the wing disk, does not induce apoptosis and has no effect on compartment growth. - substrates: Ca2+
- Cell Fitness: More Than Push-Ups.
Ferrari, International journal of molecular sciences 2021 - GeneRIF: Cell Fitness: More Than Push-Ups.
- A positive feedback loop between Flower and PI(4,5)P2 at periactive zones controls bulk endocytosis in Drosophila.
Li, eLife 2020 - GeneRIF: A positive feedback loop between Flower and PI(4,5)P2 at periactive zones controls bulk endocytosis in Drosophila.
- A Ca2+ channel differentially regulates Clathrin-mediated and activity-dependent bulk endocytosis.
Yao, PLoS biology 2017 - GeneRIF: Fwe promotes clathrin-mediated endocytosis independently of Ca2+channeling.
- Flower forms an extracellular code that reveals the fitness of a cell to its neighbors in Drosophila.
Rhiner, Developmental cell 2010 (PubMed)- GeneRIF: Our results suggest that Fwe is a component of the cell competition response that is required and sufficient to label cells as "winners" or "losers.".
- A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis.
Yao, Cell 2009 - GeneRIF: Study reports the identification of a protein that has not been previously characterized in any species and whose loss affects endocytosis. It contains three or four transmembrane domains and is associated with synaptic vesicles.
- Proteomic changes in response to crystal formation in Drosophila Malpighian tubules
Chung, Fly 2016 - “...0.045 0.036 1.425 1.408 1.057 0.563 M9PJN5 Q8IPZ3 Q95T12 9(8) 1(1) 1(1) HDAC6 CG17221 flower FBgn0026428 FBgn0031500 FBgn0261722 Zinc ion binding Vacuolar...”
- Identification of Drosophila centromere associated proteins by quantitative affinity purification-mass spectrometry
Barth, Data in brief 2015 - “...6.77.2E02 1.80E03 7.11.0E01 9.20E04 MED30 FBpp0072457 FBgn0035149 Q9W0P3 6.67.5E02 1.40E04 6.66.6E02 1.80E04 Fwe FBpp0075297 FBgn0261722 Q95T12 6.69.6E02 1.60E04 6.48.1E02 1.30E04 Rrp4 FBpp0072020 FBgn0034879 Q9W1M9 6.41.1E01 1.70E03 6.36.4E02 1.30E03 CG1789 FBpp0071194 FBgn0030063 Q9W3C0 6.32.1E02 1.10E03 6.82.7E02 7.30E04 qkr58E-2 FBpp0071739 FBgn0022985 Q9W254 6.39.7E02 1.80E04 6.16.8E02 2.10E04 prod FBpp0085785...”
Bm1_34880 LD28933p, putative from Brugia malayi
Aligns to 33:142 / 175 (62.9%), covers 100.0% of PF10233, 91.2 bits
XP_011671877 calcium channel flower homolog isoform X1 from Strongylocentrotus purpuratus
Aligns to 38:147 / 181 (60.8%), covers 97.3% of PF10233, 88.4 bits
TC 1.A.55.3.1 / Q5DFV8 Flatworm Flower homologue (195aas) from Schistosoma japonicum (see paper)
Aligns to 15:124 / 195 (56.4%), covers 91.2% of PF10233, 63.8 bits
Or search for genetic data about PF10233 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory