Family Search for PF10239 (DUF2465)
PF10239.9 hits 11 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
FA98B_HUMAN / Q52LJ0 Protein FAM98B from Homo sapiens (Human) (see 4 papers)
FAM98B / Q52LJ0 tRNA-splicing ligase complex FAM98B component (EC 6.5.1.8) from Homo sapiens (see 2 papers)
NP_775882 protein FAM98B from Homo sapiens
Aligns to 17:331 / 433 (72.7%), covers 100.0% of PF10239, 449.9 bits
- function: Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation (PubMed:28040436). Promotes colorectal cancer cell malignancy (PubMed:28040436).
subunit: Homodimer (PubMed:28040436). Component of the tRNA-splicing ligase complex (PubMed:21311021, PubMed:24870230). Interacts with FAM98A (PubMed:28040436). - Identification of HO-1 as a novel biomarker for graft acute cellular rejection and prognosis prediction after liver transplantation
Jia, Annals of translational medicine 2020 - “...Rho guanine nucleotide exchange factor 1 ARHGEF1 1.396 Q52LJ0 Isoform 2 of Protein FAM98B FAM98B 1.395 P49407 Arrestin beta 1 ARRB1 1.393 Q99733 Nucleosome...”
- Label-free LC-MS analysis of HER2+ breast cancer cell line response to HER2 inhibitor treatment
Di, Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2015 - “...) Fold change Highest condition ) a P13489 Ribonuclease inhibitor 4 310.49 0.000561 1.55 Neratinib Q52LJ0 Protein FAM98B 2 90.26 0.000932 1.62 Neratinib P49411 Elongation factor Tu, mitochondrial 3 201.31 0.001 1.52 Neratinib P35232 Prohibitin 2 118.62 0.002224 1.64 Neratinib Q8WUM4 Programmed cell death 6-interacting protein...”
- hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
Pérez-González, PloS one 2014 - “...9(7) 304 *RTCB_HUMAN tRNA-splicing ligase (HSPC 117) Q9Y3I0 55589 39(35) 1666 6(6) 248 *Protein FAM98B Q52LJ0 37489 13(13) 655 3(2) 203 Single-stranded DNA-binding protein 3 Q9BWW4 40533 2(2) 131 Transcription factor 4 P15884 71448 2(2) 120 Serrate RNA effector molecule homolog Q9BXP5 10092 2(2) 82 Heterogeneous...”
- “...423 *RTCB_HUMAN tRNA-splicing ligase (HSPC 117) Q9Y3I0 55589 64(35) 3072 8 (7) 234 *Protein FAM98B Q52LJ0 37489 34(18) 1570 3(3) 167 Putative RNA binding protein Luc7-like 1 Q9NQ29 44023 2(2) 123 Transport and cytoskeleton related factors *Myosin light chain kinase 2, skeletal/cardiac muscle Q9H1R3 65104 21(2)...”
- FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression.
Akter, The international journal of biochemistry & cell biology 2017 (PubMed)- GeneRIF: the two structural homologs FAM98A and FAM98B included in a novel complex with DDX1 and C14orf166 are required for PRMT1 expression in colorectal cancer cell lines
- hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
Pérez-González, PloS one 2014 - GeneRIF: hCLE/C14orf166 associates with DDX1, HSPC117, and FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
FA98A_HUMAN / Q8NCA5 Protein FAM98A from Homo sapiens (Human) (see paper)
Aligns to 11:328 / 518 (61.4%), covers 100.0% of PF10239, 449.1 bits
- function: Positively stimulates PRMT1-induced protein arginine methylation (PubMed:28040436). Involved in skeletal homeostasis (By similarity). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity). Promotes colorectal cancer cell malignancy (PubMed:28040436).
subunit: Interacts (via N- and C-terminus) with DDX1 (PubMed:28040436). Interacts (via N- and C-terminus) with C14orf166 (PubMed:28040436). Interacts with FAM98B (PubMed:28040436). Interacts with PLEKHM1 (via N- and C-terminus) (By similarity). - Comparative proteomic analysis of osteogenic differentiated human adipose tissue and bone marrow-derived stromal cells.
Dadras, Journal of cellular and molecular medicine 2020 - “...SET 8 P48357 Leptin receptor P11586 C1tetrahydrofolate synthase, cytoplasmic 9 Q6WCQ1 Myosin phosphatase Rhointeracting protein Q8NCA5 Protein FAM98A 10 P31513 Dimethylaniline monooxygenase [Noxideforming] 3 Q9BS40 Latexin John Wiley & Sons, Ltd Comparing the abundance of 2095 proteins quantified in 80% of both cell types revealed 281...”
- hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
Pérez-González, PloS one 2014 - “...proteins *Nuclear pore complex protein Nup153 P49790 15511 4(4) 208 1(1) 52 Others Protein FAM98A Q8NCA5 55734 14(12) 707 Nibrin O60934 85458 3(3) 119 *protein C14orf166 (CLE) Q9Y224 28143 78(21) 3899 10(10) 513 Cytosolic hCLE-associated Proteins Protein name Accession Number UniProtKB/Swiss-Prot MW (Da) Identified Pep (non-redundant)...”
- “...58 Others *Golgin subfamily A member 3 Q08378 167666 137(98) 6784 1(1) 72 *Protein FAM98A Q8NCA5 55734 20(13) 818 3(3) 183 Protein FAM98C Q17RN3 37903 5(5) 256 *Ubiquitin-40S ribosomal protein S27a P62979 18229 9(5) 447 3(3) 117 Coiled-coil domain-containing protein 8 Q9H0W5 59431 2(2) 82 *protein...”
- Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles.
Naganuma, The EMBO journal 2012 - Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery
Freibaum, Journal of proteome research 2010 - “...mago WIBG 23 Q9BRP8 3 2 17 0 0 0 * Protein FAM98A FAM98A 55 Q8NCA5 3 2 6 0 0 0 * Protein LSM12 homolog LSM12 22 Q3MHD2 3 2 14 0 0 0 * Protein PAT1 homolog 1 PATL1 87 Q86TB9 3 2 3...”
- Identification of the RGG box motif in Shadoo: RNA-binding and signaling roles?
Corley, Bioinformatics and biology insights 2008 - “...(153166) NA 42 FA98A_HUMAN, Protein FAM98A 519 RGG HEQGGG RGGRGG YDHGG RGG (352374) NA 43 (Q8NCA5) FA98A_HUMAN (Q8NCA5) 519 RGG G RGGRGGRGGRGG (458473) NA 44 LS14A_HUMAN, LSM14 protein homolog A (Q8ND56) 463 RGG YRG RGG LGF RGG RGRGGG RGG (406429) Putative alpha synuclein binding protein. a...”
- “...3 4 BRWD3_HUMAN Q6RI45 34 42 4 4 CA077_HUMAN Q9Y3Y2 4 2 0 1 FA98A_HUMAN Q8NCA5 5 9 1 LS14A_HUMAN Q8ND56 4 7 1 11 a Searches were conducted using the ScanProsite program available on the ExPASy Proteomics Server of the Swiss Institute of Bioinformatics website...”
FA98A_MOUSE / Q3TJZ6 Protein FAM98A from Mus musculus (Mouse) (see paper)
Aligns to 11:328 / 515 (61.7%), covers 100.0% of PF10239, 448.4 bits
- function: Positively stimulates PRMT1-induced protein arginine methylation (By similarity). Involved in skeletal homeostasis (PubMed:27777970). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970).
subunit: Interacts (via N- and C-terminus) with DDX1 (By similarity). Interacts (via N- and C-terminus) with C14orf166 (By similarity). Interacts with FAM98B (By similarity). Interacts with PLEKHM1 (via N- and C-terminus) (PubMed:27777970).
Q5FWT1 Protein FAM98A from Rattus norvegicus
Aligns to 11:328 / 515 (61.7%), covers 100.0% of PF10239, 447.0 bits
Q80VD1 Protein FAM98B from Mus musculus
Aligns to 17:331 / 429 (73.4%), covers 100.0% of PF10239, 446.7 bits
CG5913 uncharacterized protein from Drosophila melanogaster
Aligns to 9:333 / 454 (71.6%), covers 99.7% of PF10239, 380.1 bits
E9PH82 Protein FAM98A from Homo sapiens
Aligns to 11:301 / 312 (93.3%), covers 90.7% of PF10239, 374.5 bits
Q6AXA1 MGC80361 protein from Xenopus laevis
Aligns to 54:369 / 385 (82.1%), covers 99.7% of PF10239, 359.3 bits
- Xenopus meiotic microtubule-associated interactome
Gache, PloS one 2010 - “...Q6GQL3 XL unstudied 38.7 BAT2 Cytoplasme, spindle NA Weak signal on spindle microtubules 5 Mgc80361/ Q6AXA1 XL unstudied 42.8 Nucleus NA Spindle microtubules 6 Mgc81475/ Q6NRT3 XL Smu1 4 57.6 7 x WD LisH CTLH Cytoplasme, nucleus midbody NA Spindle microtubules, poles 7 TSGA14/ Q9BYV8 HS...”
Q17RN3 Protein FAM98C from Homo sapiens
Aligns to 15:336 / 349 (92.3%), covers 94.1% of PF10239, 299.5 bits
D4AE02 Uncharacterized protein from Rattus norvegicus
Aligns to 17:305 / 433 (66.7%), covers 90.1% of PF10239, 277.1 bits
- Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation.
Dong, Neural regeneration research 2020 - “...D3ZK01, G3V8E8, Q6PDW6, D3ZK70, Q5U2Q7, D4AAZ9, D3ZBE6, Q5FVQ2, F1LPT0, Q5I034, Q5I0K3, G3V7C4, B2RZ66, P68255, G3V6X7, D4AE02, D3ZA45, F1M1L9 CMS: Chronic mild stress group; CON: control group; KXS: Kai-Xin-San group. Functional analysis of differentially expressed proteins in KXS-treated CMS rats Biological functional analysis demonstrated that the differentially...”
NP_001291467 protein FAM98A isoform 2 from Homo sapiens
Aligns to 1:133 / 323 (41.2%), covers 40.6% of PF10239, 227.2 bits
Or search for genetic data about PF10239 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory