Family Search for PF10290 (YJL171C_Tos1_N)

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PF10290 hits 15 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TOS1_CANAL / A0A1D8PJA8 Probable circularly permuted 1,3-beta-glucanase TOS1; Secreted protein TOS1; EC 3.2.1.39 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
Aligns to 36:98 / 467 (13.5%), covers 98.4% of PF10290, 99.3 bits

• function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling (By similarity). Plays a role in engulfment by host macrophages (PubMed:26087349).
  catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
  disruption phenotype: Leads to a slight sensitivity to the cell wall damaging agent calcofluor white but not Congo red (PubMed:26087349). Increases the phagocytosis rate by host macrophages (PubMed:26087349).

TOS1_YEAST / P38288 Probable circularly permuted 1,3-beta-glucanase TOS1; Target of SBF protein 1; EC 3.2.1.39 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
Aligns to 38:100 / 455 (13.8%), covers 100.0% of PF10290, 96.6 bits

• function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
  catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
  disruption phenotype: Leads to a slight sensitivity to the cell wall damaging agent calcofluor white (PubMed:15781460). Shows also a slightly decreased ability to grow at 39 degrees Celsius (PubMed:15781460). Results in an increased resistance to Quantazyme, a recombinant beta-1,3-glucanase that hydrolyzes beta-1,3-glucan (PubMed:15781460).

PGA52_CANAL / Q59L72 Probable circularly permuted 1,3-beta-glucanase PGA52; EC 3.2.1.39 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 3 papers)
Aligns to 23:90 / 384 (17.7%), covers 96.8% of PF10290, 86.6 bits

• function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
  catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.

TOH1_YEAST / P46992 Probable circularly permuted 1,3-beta-glucanase YJL171C; TOS1 homolog; EC 3.2.1.39 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
Aligns to 26:93 / 396 (17.2%), covers 98.4% of PF10290, 84.7 bits

• function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
  catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.

PGA52_ARTBC / D4AQ83 Probable circularly permuted 1,3-beta-glucanase; Allergen Asp f 4 homolog; PGA52-like secreted protein ARB_06390; EC 3.2.1.39 from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see paper)
Aligns to 37:97 / 440 (13.9%), covers 96.8% of PF10290, 72.1 bits

• function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
  catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.

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