Family Search for PF10853 (DUF2650)

PF10853 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

SUP1_CAEEL / Q9XWU2 Protein SUP-1 from Caenorhabditis elegans (see paper)
NP_499520 Protein SUP-1 from Caenorhabditis elegans
Aligns to 49:85 / 103 (35.9%), covers 100.0% of PF10853, 67.5 bits

• function: May be involved in trafficking or stabilization of the vesicular acetylcholine transporter unc-17.
  disruption phenotype: Mild decrease in swimming behavior but otherwise no apparent phenotype.
• Genetic interactions between UNC-17/VAChT and a novel transmembrane protein in Caenorhabditis elegans.
  Mathews, Genetics 2012
  • GeneRIF: The SUP-1 gene encodes a single-pass transmembrane protein that is expressed in a subset of neurons and in body muscles. UNC-17 and SUP-1 are in close proximity at synapses.

CBG13227 Protein CBG13227 from Caenorhabditis briggsae
Aligns to 49:73 / 134 (18.7%), covers 54.1% of PF10853, 36.3 bits

• Evolutionary Dynamics of GLD-1-mRNA complexes in Caenorhabditis nematodes
  Beadell, Genome biology and evolution 2014
  • “...progeny 14 CBG05292 CBG01393 15 CBG16726 CBG05879 16 CBG08527 CBG11569 17 CBG05095 CBG09653 18 CBG10091 CBG13227 19 CBG04372 CBG04373 20 CBG03080 CBG09925 21 CBG20875 CBG14962 22 Cbr-egg-4 Cbr-tpa-1 Injected worms lay only shell-less oocytes 23 CBG00199 CBG22683 24 CBG01956 CBG02251 Low brood size from hermaphrodites with...”
  • “...no germline CBG04207 Aberrant oocytes CBG08921 Aberrant oocytes Cbr-swd-3.3 Aberrant oocytes CBG10091 Proximal oocyte necrosis CBG13227 Aberrant oocytes; laying oocytes instead of embryos Cbr-tpa-1 Aberrant oocytes CBG03085 Aberrant proximal oocytes and postpachytene cells CBG03615 Aberrant proximal oocytes and postpachytene cells CBG12096 Delayed gametogenesis; delayed self-fertility Cbr-air-1.1+1.2...”

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