Family Search for PF11187 (DUF2974)
PF11187.8 hits 27 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
BL0787 narrowly conserved hypothetical protein (NCBI) from Bifidobacterium longum NCC2705
Aligns to 88:315 / 373 (61.1%), covers 99.6% of PF11187, 308.5 bits
- The pyrE Gene as a Bidirectional Selection Marker in Bifidobacterium Longum 105-A
Sakaguchi, Bioscience of microbiota, food and health 2013 - “...longum 105-A wild-type and B. longum 105-A pyrE knockout mutants. The region flanking pyrD , BL0787, was amplified by PCR ( Table 2 , No.4). Lane M indicates the DNA marker, - Eco T14I, with the following size order from top to bottom: 19,329 bp, 7,743...”
spr1475 Hypothetical protein (NCBI ptt file) from Streptococcus pneumoniae R6
SPD_1447 hypothetical protein (NCBI) from Streptococcus pneumoniae D39
Aligns to 74:299 / 357 (63.3%), covers 99.1% of PF11187, 292.7 bits
- Penicillin induces alterations in glutamine metabolism in Streptococcus pneumoniae
El, Scientific reports 2017 - “...transporter substrate-binding protein 1.06 1.06 1.13 1.67 1.86 spr1467 rpsO 30S ribosomal protein S15 1.11 spr1475 hypothetical protein 1.00 spr1527 ABC-SBP sugar ABC transporter substrate-binding protein 1.32 spr1528 PTS-EII PTS system transporter subunit IIBC 1.42 spr1536 nanA neuraminidase A 1.58 2.00 2.58 spr1630 hypothetical protein 1.08...”
- Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39
Sinha, Journal of bacteriology 2019 - “...spd_1383 spd_1426, spd_1425 spd_1441, spd_1442 spd_1448, spd_1447 spd_1455, spd_1454 recG, spd_1506 spd_1578, spd_1577 spd_1580, spd_1582 spd_1605, spd_1604...”
- Inhibition of Autolysis by Lipase LipA in Streptococcus pneumoniae Sepsis
Kim, Molecules and cells 2017 - “...determined. LipA and autolysin (LytA) levels were determined by qPCR and western blotting. S. pneumoniae Spd_1447 in the D39 (type 2) strain was identified as a lipase (LipA). In the sepsis model, but not in the pneumonia model, mice infected with the lipA displayed higher mortality...”
- “...uptake by this cell type ( Rollof et al., 1988 ). In this study, the Spd_1447 protein was characterized as a lipase and named LipA. Unlike other pathogen lipases, the S. pneumoniae LipA was not detected in pneumococcal culture, suggesting that this lipase may play a...”
SSA_1686 hypothetical protein (NCBI) from Streptococcus sanguinis SK36
Aligns to 79:303 / 404 (55.7%), covers 99.1% of PF11187, 286.7 bits
HMPREF0389_01465 DUF2974 domain-containing protein from Filifactor alocis ATCC 35896
Aligns to 80:303 / 363 (61.7%), covers 99.1% of PF11187, 282.5 bits
- Proteome variation among Filifactor alocis strains
Aruni, Proteomics 2012 - “...Acetyl ornithine transaminase 43.5 182/0.44 19 C-9.97 EC-0.02 AA transfer class 3 domain Nonsecretory 25. HMPREF0389_01465 Conserved hypothetical protein 41.5 55/0.16 8 C-7.5 EC-0.73 Hydrolase domain Nonsecretory 26. HMPREF0389_000744 Butryl coA dehydrogenase 41.25 64/0.16 12 C-7.50 EC-0.73 Acetyl coA DH1 and DH2 domain Nonsecretory 27. HMPREF0389_00745...”
- “...protein 34. HMPREF0389_00538 Processive diacylglycerol glucosyl transferase 42.2 11/0.05 2 Unknown MGDG domain Nonsecretory 35. HMPREF0389_01465 Conserved hypothetical protein 41.5 29/0.13 4 C-7.5 EC-0.73 Hydrolase domain Nonsecretory 36. HMPREF0389_00744 Butryl coA dehydrogenase 41.25 11/0.07 2 C-7.5 EC-0.73 Acetyl coA DH1 and DH2 domain Nonsecretory 37. HMPREF0389_00745...”
LBA0019 hypothetical protein (RefSeq) from Lactobacillus acidophilus NCFM
Aligns to 74:299 / 408 (55.4%), covers 99.6% of PF11187, 271.7 bits
- S-layer associated proteins contribute to the adhesive and immunomodulatory properties of Lactobacillus acidophilus NCFM
Klotz, BMC microbiology 2020 - “..., phosphoribosylformylglycinamidine synthase subunit purS and four hypothetical proteins. Remarkably, the most notably downregulated gene, lba0019 , was the same for NCK2441, NCK2530, and NCK2608 with Log2 ratios of 0.9, 1.7, and2.9, respectively. This gene encodes an uncharacterized protein predicted to contain an alpha/beta hydrolase fold...”
- “...interactions [ 33 ]. Surprisingly, in comparison to the parent, the most significantly downregulated gene, lba0019 , was the same for all three strains. This gene likely encodes an esterase, and is co-transcribed with a putative membrane protein. Esterases are a type of hydrolase enzyme which...”
LBA0860 hypothetical protein (RefSeq) from Lactobacillus acidophilus NCFM
Aligns to 80:301 / 537 (41.3%), covers 99.6% of PF11187, 230.5 bits
OA57_07455 DUF2974 domain-containing protein from Chelonobacter oris
Aligns to 45:167 / 717 (17.2%), covers 37.5% of PF11187, 37.4 bits
BFP66_RS01095 DUF2974 domain-containing protein from Streptococcus suis
Aligns to 54:195 / 413 (34.4%), covers 39.3% of PF11187, 32.3 bits
XAC2885 phospholipase A1 (NCBI ptt file) from Xanthomonas axonopodis pv. citri str. 306
Aligns to 64:188 / 395 (31.6%), covers 37.5% of PF11187, 32.2 bits
- The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing
Bayer-Santos, PLoS pathogens 2019 - “...maltophilia is probably susceptible to the action of X . citri X-Tfes XAC4264 (unknown function), XAC2885 (putative fosfolipase), XAC2609 (peptidoglycan hydrolase), XAC1918 (putative peptidoglycan hydrolase), XAC0096 (putative HExxH metallopeptidase) and XAC0151 (unknown function) [ 10 ]. Likewise, X . citri can be expected to be susceptible...”
- “...putative X . citri T4SS substrates (residues in parenthesis): XAC4264 (140279), XAC3634 (189306), XAC3266 (735861), XAC2885 (271395), XAC2609 (315431), XAC1918 (477606), XAC1165 (1112), XAC0574 (317440), XAC0466 (488584), XAC0323 (16136), XAC0151 (120254), XAC0096 (506646) [ 10 , 30 ] to BLAST search the genome of S ....”
- Global Regulator PhoP is Necessary for Motility, Biofilm Formation, Exoenzyme Production and Virulence of Xanthomonas citri Subsp. citri on Citrus Plants
Wei, Genes 2019 - “...10 12 XAC2609 XAC2609 1.77 2.55 10 135 XAC2610 XAC2610 1.69 3.98 10 128 phlA XAC2885 2.04 1.60 10 42 XAC0323 XAC0323 2.12 2.22 10 26 HI XAC0466 2.22 8.25 10 106 Cw1L XAC3634 2.1 9.38 10 43 log 2 .Fold_change: log 2 (read count_ phoP...”
CBO2038 exported calcium-binding glycoprotein (RefSeq) from Clostridium botulinum A str. ATCC 3502
Aligns to 619:783 / 825 (20.0%), covers 58.5% of PF11187, 29.9 bits
MGL_3878 hypothetical protein from Malassezia globosa CBS 7966
Aligns to 79:224 / 302 (48.3%), covers 40.6% of PF11187, 27.2 bits
- Evaluation of Expression of Lipases and Phospholipases of Malassezia restricta in Patients with Seborrheic Dermatitis
Lee, Annals of dermatology 2013 - “...M. globosa possesses a total of 14 lipases and nine phospholipases. Among them, four lipases (MGL_3878, MGL_3507, MGL_0799, and MGL_0798) and two phospholipases (MGL_4252 and MGL_3326) were expressed on human scalps 6 . We used sequences of M. globosa lipases and phospholipases to search homologous genes...”
- “...phospholipases were expressed on surface of the host 6 . These include lipase MGL_3057, lipase MGL_3878, lipase MGL_0799, lipase MGL_0798, phospholipase MGL_4252 and phospholipase MGL_3326. Lipase MGL_0799 was of particular interest because another independent study also identified it and indicated that the gene, designated as LIP1...”
Q9X9D8 phospholipase A1 (EC 3.1.1.32) from Serratia sp. (see 2 papers)
Aligns to 121:215 / 320 (29.7%), covers 35.7% of PF11187, 26.5 bits
SG2218 putative phospholipase A (NCBI) from Sodalis glossinidius str. 'morsitans'
Q2NQT2 Putative phospholipase A from Sodalis glossinidius (strain morsitans)
Aligns to 106:212 / 315 (34.0%), covers 40.6% of PF11187, 26.1 bits
XAC0574 conserved hypothetical protein (NCBI ptt file) from Xanthomonas axonopodis pv. citri str. 306
Aligns to 37:175 / 440 (31.6%), covers 37.1% of PF11187, 26.0 bits
- The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing
Bayer-Santos, PLoS pathogens 2019 - “...parenthesis): XAC4264 (140279), XAC3634 (189306), XAC3266 (735861), XAC2885 (271395), XAC2609 (315431), XAC1918 (477606), XAC1165 (1112), XAC0574 (317440), XAC0466 (488584), XAC0323 (16136), XAC0151 (120254), XAC0096 (506646) [ 10 , 30 ] to BLAST search the genome of S . maltophilia K279a ( https://www.genome.jp/tools/blast/ ). A list of...”
sll0482 hypothetical protein (NCBI ptt file) from Synechocystis sp. PCC 6803
Aligns to 190:331 / 407 (34.9%), covers 32.1% of PF11187, 25.6 bits
- Proteomic and metabolomic analyses reveal metabolic responses to 3-hydroxypropionic acid synthesized internally in cyanobacterium Synechocystis sp. PCC 6803
Wang, Biotechnology for biofuels 2016 - “...RT-PCR analysis. Among them, 10 proteins were down-regulated (i.e., Sll0992, Ssl2667, Ssr2061, Slr0447, Sll0541, Slr1019, Sll0482, Slr1856, Sll1087 and Slr1200) and 10 proteins were up-regulated (i.e., Slr0420, Sll1773, Slr0431, Slr1227, Sll1869, Sll0385, Sll1699, Slr0844, Sll1598 and Sll1491) according to the iTRAQ proteomic analysis, respectively. Comparative RT-PCR...”
- “...0.680.23 Urea/short-chain amide ABC transporter sll0541 0.650.13 0.750.29 Delta -9 desaturase slr1019 0.560.08 1.750.35 PhzF sll0482 0.750.21 2.060.98 Lipase precursor slr1856 0.790.11 2.210.57 Sigma regulatory factor sll1087 0.830.10 0.890.32 Sodium-coupled permease slr1200 0.750.05 1.080.20 Urea/short-chain amide ABC transporter, permease protein Overexpression and validation of genes relevant...”
- Highly expressed and alien genes of the Synechocystis genome
Mrázek, Nucleic acids research 2001 - “...1.10], sll0481 [154 amino acids, E(g) = 1.07] and sll0482 [406 amino acids, E(g) = 1.05]. sll0480 is probably an aminotransferase, whereas sll0481 and sll0482...”
BATDEDRAFT_26491 uncharacterized protein from Batrachochytrium dendrobatidis JAM81
Aligns to 221:363 / 470 (30.4%), covers 37.9% of PF11187, 25.5 bits
lmo2804 lmo2804 (NCBI ptt file) from Listeria monocytogenes EGD-e
Aligns to 125:285 / 427 (37.7%), covers 52.2% of PF11187, 24.8 bits
XC_0586 hypothetical protein (NCBI) from Xanthomonas campestris pv. campestris str. 8004
Aligns to 37:147 / 437 (25.4%), covers 35.3% of PF11187, 24.5 bits
- A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis
An, The EMBO journal 2013 - “...by RNA-Seq (dark grey) and qRTPCR (light grey). Mutation of XC_0250 affected transcript levels of XC_0586 (lipase), XC_1019 (hypothetical protein), XC_0870 (secreted protein), XC_1036 (GGDEF domain), XC_1213 (peptidase), XC_1413 (chemotaxis protein), XC_2224 (secreted protein) and XC_3591 (pectate lyase). In trans expression of XC_0250 (cloned as pXC_0250)...”
Q481Z4 Lipase family protein from Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
Aligns to 89:261 / 357 (48.5%), covers 52.7% of PF11187, 24.5 bits
O85477 Phospholipase A from Yersinia enterocolitica (type O:8)
YE1005 phospholipase A (NCBI) from Yersinia enterocolitica subsp. enterocolitica 8081
Aligns to 127:220 / 324 (29.0%), covers 35.7% of PF11187, 24.0 bits
SAK_0322 hypothetical protein (NCBI) from Streptococcus agalactiae A909
Aligns to 97:303 / 544 (38.1%), covers 54.5% of PF11187, 23.4 bits
Ot06g03510 Lipase, class 3 from Ostreococcus tauri
Aligns to 135:288 / 515 (29.9%), covers 46.9% of PF11187, 22.6 bits
- Shikimate and phenylalanine biosynthesis in the green lineage
Tohge, Frontiers in plant science 2013 - “...4 OT 8 SB 9 ZM 10 BD 11 OS 12 OSindica DHS Cr17g06460 Mrcc02g07760 Ot06g03510 Sb01g028770 Zm02g39200 Bd1g21330 Os03g27230 Osi07g35030 Sb01G033590 Zm04g31550 Bd1g60750 Os07g42960 Osi08g36090 Sb02G039660 Zm05g06990 Bd3g33650 Os08g37790 Osi10g31830 Sb07G029080 Bd3g38670 Os10g41480 DQS Cr08g02240 Mrcc01g05190 Ot05g01830 Sb02G031240 Zm02g34320 Bd4g36507 Os09g36800 Osi09g29080 DHQD Cr08g04550 Mrcc01g03580...”
YPO2706 phospholipase A (NCBI ptt file) from Yersinia pestis CO92
YPTB2902 phospholipase A (NCBI) from Yersinia pseudotuberculosis IP 32953
Aligns to 124:224 / 320 (31.6%), covers 31.2% of PF11187, 22.4 bits
AT5G24180 lipase class 3-related (RefSeq) from Arabidopsis thaliana
Aligns to 100:193 / 375 (25.1%), covers 29.9% of PF11187, 22.1 bits
P18952 Extracellular phospholipase A1 from Serratia liquefaciens
Aligns to 122:213 / 319 (28.8%), covers 35.7% of PF11187, 22.0 bits
- A novel phospholipase from Trypanosoma brucei
Richmond, Molecular microbiology 2007 - “...YplA, Yersinia enterocolitica PLA 1 (Accession Number O85477); PhlA, Serratia liquefaciens PLA 1 (Accession Number P18952). Fig. 2 Purification and regiospecificity of recombinant TbPLA 1 . A. SDS-PAGE analysis of proteins from TbPLA 1 -overexpressing E. coli cells during various purification steps as compared with molecular...”
B178_09868 non-ribosomal peptide synthetase from Corynebacterium diphtheriae DSM 43988
Aligns to 214:296 / 442 (18.8%), covers 23.7% of PF11187, 22.0 bits
A9X3M0 phospholipase A1 (EC 3.1.1.32) from Serratia sp. xJF1 (see paper)
Aligns to 127:224 / 320 (30.6%), covers 31.2% of PF11187, 21.9 bits
Or search for genetic data about PF11187 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory