Family Search for PF11738 (DUF3298)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF11738 hits 59 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

RSIV_BACSU / O05403 Anti-sigma-V factor RsiV from Bacillus subtilis (strain 168) (see 2 papers)
Aligns to 189:272 / 285 (29.5%), covers 98.8% of PF11738, 84.4 bits

• function: Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction.
  subunit: Interacts (via N-terminal region) with SigV.

ESTR2_MYCTU / I6YF08 Esterase Rv3036c; EC 3.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
Aligns to 144:220 / 227 (33.9%), covers 98.8% of PF11738, 51.8 bits

• function: Hydrolyzes ester substrates carbon chain lengths ranging from C2 to C14 (PubMed:25224799). In vitro, acetate (C2), butyrate (C4) and caprylate (C6) are hydrolyzed with high efficiency. Has lower activity against laurate (C12), myristate (C14) and caproate (C8), and weak activity against palmitate (C16) (PubMed:25224799).
  catalytic activity: a fatty acid ester + H2O = a fatty acid + an aliphatic alcohol + H(+) (RHEA:59388)
  catalytic activity: an acetyl ester + H2O = acetate + an aliphatic alcohol + H(+) (RHEA:12957)
  catalytic activity: a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+) (RHEA:47348)
  catalytic activity: a hexanoate ester + H2O = an aliphatic alcohol + H(+) + hexanoate (RHEA:47352)
  catalytic activity: a dodecanoate ester + H2O = an aliphatic alcohol + dodecanoate + H(+) (RHEA:47364)
  catalytic activity: a tetradecanoate ester + H2O = an aliphatic alcohol + H(+) + tetradecanoate (RHEA:47388)
  catalytic activity: an octanoate ester + H2O = an aliphatic alcohol + H(+) + octanoate (RHEA:47356)

PDAC_BACSU / O34798 Peptidoglycan-N-acetylmuramic acid deacetylase PdaC; Peptidoglycan MurNAc deacetylase; Polysaccharide deacetylase PdaC; EC 3.5.1.- from Bacillus subtilis (strain 168) (see 2 papers)
Aligns to 156:235 / 467 (17.1%), covers 98.8% of PF11738, 48.5 bits

• function: Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan, a modification that confers resistance to lysosyme. Is not able to deacetylate N-acetylglucosamine (GlcNAc) residues in peptidoglycan, but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc.
  disruption phenotype: Cells lacking this gene show sensitivity to lysosyme, in contrast to wild-type.

Or search for genetic data about PF11738 in the Fitness Browser