Family Search for PF11999 (Ice_binding)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

Running HMMer for PF11999

PF11999 hits 15 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

IBP_LEUSY / C7F6X3 Ice-binding protein; Antifreeze protein; AFP; LeIBP from Leucosporidium sp. (strain AY30) (Arctic yeast) (see 6 papers)
Aligns to 36:241 / 261 (78.9%), covers 100.0% of PF11999, 212.6 bits

• function: Confers freeze tolerance. Binds to the surface of ice crystals and inhibits their growth. Has low thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point (PubMed:24699650, PubMed:22303017, PubMed:20067781, PubMed:22426061, PubMed:23203635, PubMed:22622645). The TH activity of this protein is approximately 0.2 degrees Celsius at 50 uM and 0.3 degrees Celsius at 400 uM (PubMed:24699650).
  subunit: Homodimer (PubMed:22426061, PubMed:24699650, PubMed:22303017). Dimerization is not required for the thermal hysteresis (TH) activity (PubMed:22303017).

IBPKB_TYPIS / Q76CE6 Ice-binding protein K3-B1; Antifreeze protein 6; AFP6; TAFP-2; TisAFP6 from Typhula ishikariensis (Gray snow mold fungus) (see 2 papers)
Aligns to 36:241 / 243 (84.8%), covers 99.5% of PF11999, 210.8 bits

• function: Binds to the surface of ice crystals. Has low thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point (PubMed:22645341). The TH activity of this protein is approximately 0.3 degrees Celsius at 11 mM (PubMed:27613857).

IBP_FLAFP / H7FWB6 Ice-binding protein; Antifreeze protein; AFP; FfIBP from Flavobacterium frigoris (strain PS1) (see 3 papers)
Aligns to 75:273 / 276 (72.1%), covers 100.0% of PF11999, 209.1 bits

• function: Has antifreeze activity for survival in a subzero environment. Binds to the surface of ice crystals and inhibits their growth. Has high thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point, and thus the freezing of the cell fluid can be prevented protecting the organism from ice damage (PubMed:22750870, PubMed:24699650, PubMed:27737617). The TH activity of this protein is 2.2 degrees Celsius at 5 uM and 2.5 degrees Celsius at 50 uM (PubMed:24699650).
  subunit: Monomer.

IBP_COLSX / A5XB26 Ice-binding protein; Antifreeze protein; AFP from Colwellia sp. (see 2 papers)
Aligns to 43:242 / 253 (79.1%), covers 100.0% of PF11999, 208.9 bits

• function: Binds to the surface of ice crystals and inhibits their growth (PubMed:17651136, PubMed:24938370). Has ice recrystallization inhibition (RI) activity (the ability to prevent the formation of larger grains of ice at the expense of smaller grains), which may protect membranes from freezing injury (Probable). Has high thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point, and thus the freezing of the cell fluid can be prevented protecting the organism from ice damage. The TH activity of this protein is 3.8 degrees Celsius at 14 mM (PubMed:24938370).

IBPKA_TYPIS / Q76CE8 Ice-binding protein K1-A; Antifreeze protein 8; AFP8; TAFP-3; TisAFP8 from Typhula ishikariensis (Gray snow mold fungus) (see 2 papers)
Aligns to 36:241 / 243 (84.8%), covers 99.5% of PF11999, 206.8 bits

• function: Binds to the surface of ice crystals (Ref.1, PubMed:20030710, PubMed:27613857). Inhibits growth of the ice crystals (PubMed:20030710). Has antifreeze activity for survival under snow cover. Has high thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point, and thus the freezing of the cell fluid can be prevented protecting the organism from ice damage (PubMed:20030710, PubMed:27613857). The TH activity of this protein is 2.0 degrees Celsius at 0.11 mM (PubMed:27613857).

IBP1_SHEFN / Q086E4 Ice-binding protein 1; Antifreeze protein 1; AFP 1; Ice adhesin 1 from Shewanella frigidimarina (strain NCIMB 400) (see paper)
Aligns to 670:889 / 892 (24.7%), covers 100.0% of PF11999, 200.5 bits

• function: Ice-binding adhesion protein that adsorbs this bacterium onto ice to maintain a favorable position in its aquatic habitat. Inhibits growth of the ice crystals. Has high thermal hysteresis (TH) activity, which is the ability to lower the freezing point of an aqueous solution below its melting point. The TH activity of this protein is approximately 1.4 degrees Celsius at 25 uM and little below 2 degrees Celsius at 80 uM.

Or search for genetic data about PF11999 in the Fitness Browser