Family Search for PF13251 (DUF4042)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF13251 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

HEAT6_HUMAN / Q6AI08 HEAT repeat-containing protein 6; Amplified in breast cancer protein 1 from Homo sapiens (Human) (see paper)
NP_071353 HEAT repeat-containing protein 6 from Homo sapiens
Aligns to 418:599 / 1181 (15.4%), covers 100.0% of PF13251, 224.8 bits

• function: Amplification-dependent oncogene
• [The relationship between the expression of amplified in breast cancer 1、androgen receptor and tamoxifen resistance in breast cancer].
  Liu, Zhonghua yi xue za zhi 2023 (PubMed)
  • GeneRIF: [The relationship between the expression of amplified in breast cancer 1androgen receptor and tamoxifen resistance in breast cancer].

AT4G38120 binding from Arabidopsis thaliana
Aligns to 389:575 / 1165 (16.1%), covers 98.9% of PF13251, 207.4 bits

• New insights into QTNs and potential candidate genes governing rice yield via a multi-model genome-wide association study
  Sachdeva, BMC plant biology 2024 (no snippet)
• Use of Arabidopsis thaliana as a model to understand specific carcinogenic events: Comparison of the molecular machinery associated with cancer-hallmarks in plants and humans
  Clavijo-Buriticá, Heliyon 2023
  • “...and HEATR6 genes, orthologs of the A.thaliana AT1G72320 and AT4G38120 genes, reduced cell division in the analyzed cell cultures [11 ]. Even more, we showed...”
• Transcriptome-wide high-throughput deep m(6)A-seq reveals unique differential m(6)A methylation patterns between three organs in Arabidopsis thaliana
  Wan, Genome biology 2015
  • “...AT2G07671, AT2G07708, AT2G07687, AT2G07727, AT2G11910, AT2G31141, AT2G33980, AT2G35750, AT2G07698, AT3G12590, AT3G41762, AT3G50380, AT4G00585, AT4G02770, AT4G31350, AT4G38120, AT4G39690, AT5G08060, AT5G15320, AT5G15750, AT5G26850, AT5G59613, AT1G07705, AT3G58010, AT3G63052, AT1G30910, AT3G08950, AT3G47060, AT2G07715, AT1G10522, AT3G06310, AT1G31860, AT5G53740, AT1G49700, AT4G31390, AT2G21340, AT3G43540, AT2G25660, AT5G66380, AT1G45332, AT5G61310, AT5G15700, AT3G18040, AT3G56120, AT4G01210, AT4G00630,...”
  • “...r EA for AT5G22700, s RA for AT3G13400, t EA for AT3G13400, u EA for AT4G38120, v EA for AT4G38120. (DOC 1342 kb) Additional file 11: Figure S3. RNA QC results of the total RNA and the RIP RNA for m 6 A-seq samples. a RNA...”

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