Family Search for PF13300 (DUF4078)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF13300 hits 4 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

CC174_HUMAN / Q6PII3 Coiled-coil domain-containing protein 174 from Homo sapiens (Human) (see paper)
Aligns to 214:302 / 467 (19.1%), covers 100.0% of PF13300, 91.9 bits

• function: Probably involved in neuronal development.
• Screening and Identification of APOC1 as a Novel Potential Biomarker for Differentiate of Mycoplasma pneumoniae in Children.
  Li, Frontiers in microbiology 2016
  • “...isoform 1 RBBP6 Q7Z6E9 201.4 10.2 89.3 2.174 0.529 gi|108773808 Coiled-coil domain-containing protein 174 CCDC174 Q6PII3 53.9 6 84.6 0.361 0.266 gi|262118216 Coiled-coil domain-containing protein 88B precursor CCDC88B A6NC98 164.7 4.9 83.1 2.273 0.328 gi|140161498 Microtubule-associated tumor suppressor candidate 2 isoform a MTUS2 Q5JR59 151.1 6.3...”

Q5PQS7 Coiled-coil domain-containing protein 174 from Rattus norvegicus
Aligns to 223:311 / 474 (18.8%), covers 100.0% of PF13300, 91.9 bits

• Proteomic analysis of immature rat pups brain in response to hypoxia and ischemia challenge.
  Yang, International journal of clinical and experimental pathology 2014

NP_001069046 coiled-coil domain-containing protein 174 from Bos taurus
Aligns to 214:302 / 467 (19.1%), covers 100.0% of PF13300, 91.4 bits

• Orchestrating the expression levels of sperm mRNAs reveals CCDC174 as an important determinant of semen quality and bull fertility.
  Selvaraju, Systems biology in reproductive medicine 2021 (PubMed)
  • GeneRIF: Orchestrating the expression levels of sperm mRNAs reveals CCDC174 as an important determinant of semen quality and bull fertility.

YK24_SCHPO / Q9P7B7 Uncharacterized protein C140.04 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
SPAC140.04 conserved fungal protein from Schizosaccharomyces pombe
Aligns to 194:278 / 295 (28.8%), covers 91.9% of PF13300, 69.8 bits

• Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance
  Lee, Cell 2013
  • “...homolog of C. elegans NRDE-2, Nrl1 ( SPBC20F10.05 ), and the coiled-coil and DUF4078-domain-containing protein SPAC140.04 , which we named Ctr1 ( Figures 1B and 1F ). Ctr1 is evolutionarily conserved and shares homology with human CCDC174 protein of unknown function ( Figure S1B ). We...”

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