Family Search for PF13926 (DUF4211)

PF13926 hits 11 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

XP_005274349 coiled-coil domain-containing protein 82 isoform X1 from Homo sapiens
Q8N4S0 Coiled-coil domain-containing protein 82 from Homo sapiens
Aligns to 297:449 / 544 (28.1%), covers 100.0% of PF13926, 120.4 bits

• Genetic diagnosis in Sudanese and Tunisian families with syndromic intellectual disability through exome sequencing.
  Yahia, Annals of human genetics 2022 (PubMed)
  • GeneRIF: Genetic diagnosis in Sudanese and Tunisian families with syndromic intellectual disability through exome sequencing.
• The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores
  Burigotto, 2023
• Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF‑κB in lung cancer
  Jin, International journal of oncology 2023
  • “...39.308 1.466 0.019 Q9Y2K1 ZBTB1 Zinc finger and BTB domain-containing protein 1 82.016 1.451 0.036 Q8N4S0 CCDC82 Coiled-coil domain-containing protein 82 64.002 1.433 0.013 P31271 HOXA13 Homeobox protein Hox-A13 39.727 1.432 0.023 Q9BTE1 DCTN5 Dynactin subunit 5 20.127 1.357 0.036 Q9UII2 ATP5IF1 ATPase inhibitor, mitochondrial 12.249...”
• [Procine recombinant NK-lysin inhibits hepatocellular carcinoma metastasis by downregulating FKBP3 and inhibiting oxidative phosphorylation and glycolysis: a proteomic analysis].
  Fan, Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023

YE06_SCHPO / O13803 Uncharacterized protein C17H9.06c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
Aligns to 366:499 / 601 (22.3%), covers 99.3% of PF13926, 116.8 bits

F1MEZ4 Coiled-coil domain containing 82 from Bos taurus
Aligns to 278:427 / 522 (28.7%), covers 99.3% of PF13926, 114.4 bits

• Silver nanoparticle protein corona composition in cell culture media
  Shannahan, PloS one 2013
  • “...stabilized silver E1BK41 ADAMTSL1 ADAMTS-like 1 (Punctin-1) 557,764 E1BMW2 AP2A1 AP-2 complex subunit alpha-1 1,701,020 F1MEZ4 CCDC82 Coiled-coil domain containing 82 4,096,417 E1BK20 GCKR Glucokinase regulatory protein 2,656,407 F1MXJ6 KALRN Kalirin 10,814,400 A1L595 KRT17 Keratin, type I cytoskeletal 17 2,022,711 A1A4K4 LLGL1 Lethal giant larvae homolog...”

CNAG_07564 hypothetical protein from Cryptococcus neoformans var. grubii H99
Aligns to 399:534 / 712 (19.1%), covers 100.0% of PF13926, 100.1 bits

• Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
  Jung, mBio 2019
  • “...analyze those in the following categories: (i) evolutionarily divergent genes, such as C. neoformans 07564 (CNAG_07564), CNAG_05341, and CNAG_03906, and (ii) evolutionarily conserved but hitherto-uncharacterized C. neoformans genes. The latter included CNAG_02512 and CNAG_03654, which are highly orthologous to S. cerevisiae Rad16 and Sgs1, respectively. First,...”
  • “...genes induced after radiation exposure in our previous study ( 25 ), we designated CNAG_05341, CNAG_07564, and CNAG_03906 RIG4 , RIG5 , and RIG6 , respectively. To elucidate the function of the five Rad53-dependent genes, we generated rig4 , rig5 , rig6 , rad16 , and...”

QSER1_HUMAN / Q2KHR3 Glutamine and serine-rich protein 1 from Homo sapiens (Human) (see paper)
Aligns to 1485:1646 / 1735 (9.3%), covers 96.4% of PF13926, 81.8 bits

• function: Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation.
  subunit: Interacts with TET1.
• Systematic identification of recognition motifs for the hub protein LC8
  Jespersen, Life science alliance 2019
  • “...POU2F1 ESGDGNTG TQT NGL 13 26 N P35568 IRS1 LPRKVDTA AQT NSR 841 854 N Q2KHR3 QSER1 KTLTFSGS SQT VTP 374 387 N Q99814 EPAS1 TEAKDQCS TQT DFN 509 522 N Q9Y4K1 CRYBG1 RSFVLPVES TQD VSSQ 550 565 N P49862 KLK7 SFRHPGYS TQT HVN 98 111...”
• Identification of the BRD1 interaction network and its impact on mental disorder risk.
  Fryland, Genome medicine 2016
  • “...ribosomal protein S14 1.510 3 ING4 Q9UNL4 Inhibitor of growth protein 4 6.210 3 QSER1 Q2KHR3 Glutamine and serine-rich protein 1 6.410 3 2 YWHAZ P63104 14-3-3 protein zeta/delta <110 10 CLTC Q00610 Clathrin heavy chain 1 9.810 4 3 H3F3A/HIST1H3/HIST3H3 c P84243/P68431/Q16695 c Histone H3.3/Histone...”
• Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.
  Teo, Nature chemical biology 2010
  • “...(14) CTD110.6 P49790 NUP153 Nuclear pore complex protein Nup153 3 6 30 22 Tp N Q2KHR3 QSER1 Glutamine and serine-rich protein 1 (FLJ21924) 1 2 11 3 U U Q02543 RPL18A 60S ribosomal protein L18a 4 3 3 3 Tl C No,M P35658 NUP214 Nuclear pore...”

XP_047283567 glutamine and serine-rich protein 1 isoform X1 from Homo sapiens
Aligns to 1666:1826 / 1915 (8.4%), covers 96.4% of PF13926, 81.5 bits

• QSER1 protects DNA methylation valleys from de novo methylation.
  Dixon, Science (New York, N.Y.) 2021
  • GeneRIF: QSER1 protects DNA methylation valleys from de novo methylation.

Q8IQV6 Uncharacterized protein, isoform A from Drosophila melanogaster
Aligns to 934:1073 / 1173 (11.9%), covers 89.1% of PF13926, 60.1 bits

• The protein-protein interaction network of eyestalk, Y-organ and hepatopancreas in Chinese mitten crab Eriocheir sinensis
  Hao, BMC systems biology 2014
  • “...as receptors of signaling factor or the regulators of signaling pathways. For example, 16 proteins (Q8IQV6, Q7JXG9, Q8IR25, D3ZE26, Q9V3S7, Q9V3A8, Q7KMH9, Q7JPS2, Q9VVK8, Q9W1A7, Q7KN04, Q8SZY2, Q9VUP0, Q9VVU1, Q9VLK8, A1ZA45) were annotated as Hippo signaling cascade and 12 other proteins (Q8IQV6, Q7JXG9, Q8IR25, Q9V3S7, Q9V3A8,...”

XP_005156072 proline-rich protein 12 isoform X2 from Danio rerio
Aligns to 2324:2444 / 2531 (4.8%), covers 65.7% of PF13926, 47.8 bits

• Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.
  Muscò, Genes 2024
  • GeneRIF: Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.

PRR12_MOUSE / E9PYL2 Proline-rich protein 12 from Mus musculus (Mouse) (see paper)
Aligns to 1817:1944 / 2035 (6.3%), covers 83.9% of PF13926, 46.3 bits

XP_686084 proline-rich protein 12 isoform X1 from Danio rerio
X1WDQ3 Proline-rich 12b from Danio rerio
Aligns to 2447:2568 / 2656 (4.6%), covers 62.0% of PF13926, 46.2 bits

• Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.
  Muscò, Genes 2024
  • GeneRIF: Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.
• Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development
  Muscò, Genes 2024
  • “...19 ]. The following UniProt IDs were used: human PRR12 (Q9ULL5), zebrafish Prr12a-201 (A0A0R4IRJ4), Prr12b-201 (X1WDQ3), and Prr12b-202 (A0A2R8PZ98). To find evidence for the conservation of synteny, a comparison of genes neighboring human PRR12 and zebrafish chromosome 3 and 12, the Genomicus database [ 20 ]...”

PRR12_HUMAN / Q9ULL5 Proline-rich protein 12 from Homo sapiens (Human) (see 3 papers)
Aligns to 1819:1945 / 2036 (6.2%), covers 83.2% of PF13926, 46.1 bits

• Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development
  Muscò, Genes 2024
  • “...UniProt database [ 18 , 19 ]. The following UniProt IDs were used: human PRR12 (Q9ULL5), zebrafish Prr12a-201 (A0A0R4IRJ4), Prr12b-201 (X1WDQ3), and Prr12b-202 (A0A2R8PZ98). To find evidence for the conservation of synteny, a comparison of genes neighboring human PRR12 and zebrafish chromosome 3 and 12, the...”
• Blood Plasma Circulating DNA-Protein Complexes: Involvement in Carcinogenesis and Prospects for Liquid Biopsy of Breast Cancer.
  Shefer, Journal of personalized medicine 2023
  • “...Q9BT49 Q9BY07 Q9BYE3 Q9H000 Q9H239 Q9H2G4 Q9H6E4 Q9H6Y7 Q9HCP0 Q9NS84 Q9NYL4 Q9NZE8 Q9NZU5 Q9P126 Q9UKG4 Q9ULL5 Q9UPG8 Q9UQ90 Q9Y3C8 Q9Y3M8 * Proteins that negatively regulate the process are marked with hatching. Legend: HF; BCP; universal. jpm-13-01691-t004_Table 4 Table 4 Potential proteomic markers of breast cancer in...”
• Dominant variants in PRR12 result in unilateral or bilateral complex microphthalmia.
  Reis, Clinical genetics 2021
  • “...is displayed above with protein structure indicated below. Protein domains are denoted based on Uniprot Q9ULL5 (Pro-rich 161 306; Gly-rich 335 685; Pro-rich 764 1545; Pro-rich 1666 1737). Table 1: Summary of novel and previously reported pathogenic PRR12 variants. ID Age; ancestry DNA change a Predicted...”
• Splicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particles
  Yoshikawa, Molecular & cellular proteomics : MCP 2011
  • “...122 123 124 Q6P158 Q69YN4 Q9BX40 Q9Y520 Q9ULL5 Q96DN6 Q9UNF1 Q9NXS2 Q96SL8 Q68CQ4 Q9H0W5 DHX57_HUMAN VIR_HUMAN LS14B_HUMAN BA2L2_HUMAN PRR12_HUMAN MBD6_HUMAN...”

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