Family Search for PF14393 (DUF4422)

PF14393.6 hits 12 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

LSL_1574 Glycosyltransferase (NCBI) from Lactobacillus salivarius subsp. salivarius UCC118
Aligns to 6:227 / 270 (82.2%), covers 99.1% of PF14393, 296.4 bits

• Selection of Immunobiotic Ligilactobacillus salivarius Strains from the Intestinal Tract of Wakame-Fed Pigs: Functional and Genomic Studies
  Zhou, Microorganisms 2020 (no snippet)
• Phylogenomics and comparative genomics of Lactobacillus salivarius, a mammalian gut commensal
  Harris, Microbial genomics 2017
  • “...of EPS cluster 2 are shared by all the strains ( Fig. 9 ; from LSL_1574 to LSL_1569 and from LSL_1551 to LSL_1547). However, variations exist in the middle of EPS cluster 2 and six groups were identified as described in Fig. S2. Group 1 contained...”

GI|68643903 capsular biosynthesis protein from Streptococcus pneumoniae (see paper)
Aligns to 5:226 / 263 (84.4%), covers 99.6% of PF14393, 293.1 bits

lp_1180 glycosyltransferase (NCBI ptt file) from Lactobacillus plantarum WCFS1
Aligns to 4:221 / 258 (84.5%), covers 99.6% of PF14393, 285.3 bits

• Oleuropein Transcriptionally Primes Lactobacillus plantarum to Interact With Plant Hosts
  Santamaría, Frontiers in microbiology 2019
  • “...different surface polysaccharide gene clusters contained in the L. plantarum genome, cps1 ( cps1D or lp_1180 , cps1H or lp_1184 , cps1I or lp_1185 ), cps2 ( cps2A or lp_1197 , cps2B or lp_1198 , cps2E or lp_1201 , cps2F or lp_1202 , cps2G or lp_1203...”
• Exploring Lactobacillus plantarum genome diversity by using microarrays
  Molenaar, Journal of bacteriology 2005
  • “...from a non-ribosomal protein biosynthesis cluster lp_1180, lp_1186, lp_1190, lp_1202 .......Some genes from an exopolysaccharide biosynthesis cluster...”

BEN15_RS08540, DIS31_02560, T303_06385 DUF4422 domain-containing protein from Streptococcus thermophilus
Aligns to 5:225 / 259 (85.3%), covers 99.1% of PF14393, 282.4 bits

• The N-terminal domain of rhamnosyltransferase EpsF influences exopolysaccharide chain length determination in Streptococcus thermophilus 05-34
  Wang, PeerJ 2020
  • “...inactivated gene. The central region of the eps cluster encodes an EPS biosynthesis protein EpsG (DIS31_02560) with unknown function, and several glycosyltransferases. Among them, EpsE (DIS31_02540) was 100% identical to the priming glycosyltransferase of S. thermophilus NCFB 2393, which was shown to transfer glucosyl 1-phosphate to...”
• Functional Genomic Analyses of Exopolysaccharide-Producing Streptococcus thermophilus ASCC 1275 in Response to Milk Fermentation Conditions
  Wu, Frontiers in microbiology 2019
  • “...(detected proteins) highlighted in red indicates up-DEPs. As for EPS biosynthesis, only five proteins (T303_06336, T303_06385, T303_06400, T303_06410 and T303_06415) out of 20 EPS assembly associated proteins were confidently detected by iTRAQ-based method ( Supplementary Table S2 ); only EpsB (T303_06415) was identified as the down-regulated...”
• Comparative mRNA-Seq Analysis Reveals the Improved EPS Production Machinery in Streptococcus thermophilus ASCC 1275 During Optimized Milk Fermentation
  Wu, Frontiers in microbiology 2018
  • “...release EPS. As presented in Figure 4 , a similar expression pattern (from T303_06320 to T303_06385) was observed in Cd2, Cd3, and Cd4 compared to that in Cd1; this suggests that temperature increase (Cd3 vs. Cd2) and WPI supplementation (Cd4 vs. Cd2) did not alter the...”
• Complete Genome Sequence of Streptococcus thermophilus KLDS 3.1003, A Strain with High Antimicrobial Potential against Foodborne and Vaginal Pathogens
  Evivie, Frontiers in microbiology 2017
  • “...S. thermophilus KLDS3.1003 genome also contains epsA (BEN15_RS08575), epsB (BEN15_RS08570), epsE (BEN15_RS08555), epsF (BEN15_RS08550), epsG (BEN15_RS08540), epsH (BEN15_08530), epsI (BEN15_08530), eps J (BEN15_RS08530), eps K (BEN15_RS08515), epsL (BEN15_RS08510), epsM (BEN15_RS08505), epsN (BEN15_RS08500), epsO (BEN15_RS0190), epsP (BEN15_RS08475), epsQ (BEN15_RS00260, BEN15_RS00265), and transposase (BEN15_RS08545). Some of these have...”

lp_1227 polysaccharide biosynthesis protein (NCBI ptt file) from Lactobacillus plantarum WCFS1
Aligns to 4:220 / 258 (84.1%), covers 99.6% of PF14393, 277.8 bits

• An agr-like two-component regulatory system in Lactobacillus plantarum is involved in production of a novel cyclic peptide and regulation of adherence
  Sturme, Journal of bacteriology 2005
  • “...to lp_1190), cps2 (lp_1197 to lp_1211), cps3 (lp_1215 to lp_1227), and cps4 (lp_2099 to lp_2108) (27). The number of ORFs showing altered gene expression in the...”

D805_0356 DUF4422 domain-containing protein from Bifidobacterium thermophilum RBL67
Aligns to 20:245 / 282 (80.1%), covers 98.3% of PF14393, 270.2 bits

• Bifidobacterium thermophilum RBL67 impacts on growth and virulence gene expression of Salmonella enterica subsp. enterica serovar Typhimurium
  Tanner, BMC microbiology 2016
  • “...glycosyl transferase, group 1 family protein 2.07 4.79 3.0E-10 D805_0355 hypothetical protein 1.34 6.14 4.5E-06 D805_0356 Glycosyltransferase (EC 2.4.1.-) 2.14 4.96 1.5E-15 D805_0512 hypothetical protein 2.01 2.39 0.03026 D805_0524 D-lactate dehydrogenase (EC 1.1.1.28) 2.85 3.15 0.00049 D805_0525 Aspartate aminotransferase (EC 2.6.1.1) 1.91 3.11 0.01352 D805_0652 Oligopeptide...”

AAC98416.1 LPS [galactan I] α-1,3-galactopyranosyltransferase (WbbM;RfbC) (EC 2.4.1.-) (see protein)
Aligns to 10:251 / 635 (38.1%), covers 99.1% of PF14393, 249.0 bits

LGG_02048 lipo/exopolysaccharide biosynthesis glycosyltransferase / EpsF/EpsIID (RefSeq) from Lactobacillus rhamnosus GG
Aligns to 4:222 / 265 (82.6%), covers 99.6% of PF14393, 247.1 bits

• A network-based approach to identify substrate classes of bacterial glycosyltransferases
  Sánchez-Rodríguez, BMC genomics 2014
  • “...[ 37 , 44 ], our analysis only missed welJ , annotated as alpha-1,3-galactosyltransferase ( LGG_02048 ), as this gene was not predicted as a GT in our analysis. This gene does not appear to contain any signatures of the currently known HMMs for GTs and...”

KP1_3696 putative glycosyltransferase (RefSeq) from Klebsiella pneumoniae NTUH-K2044
Aligns to 6:247 / 631 (38.4%), covers 99.1% of PF14393, 246.5 bits

• D-galactan II is an immunodominant antigen in O1 lipopolysaccharide and affects virulence in Klebsiella pneumoniae: implication in vaccine design
  Hsieh, Frontiers in microbiology 2014
  • “...function Locus tag (NTUH-K2044 ORF) Gene size (bp) Tn insertion point 3-4A wbbM Putative glycosyltransferase KP1_3696 1908 1207 4-5B wbbO Bifunctional galactosyltransferase KP1_3693 1143 70 7-6D wbbM putative glycosyltransferase KP1_3696 1908 1647 9-3E wbbN Putative glycosyltransferase KP1_3694 894 293 9-10D wbbM Putative glycosyltransferase KP1_3696 1908 1635...”
  • “...component KP1_3697 741 149 25-3F wbbN Putative glycosyltransferase KP1_3694 894 280 25-8H wbbM Putative glycosyltransferase KP1_3696 1908 1056 26-8B glf Putative UDP-galactopyranose mutase KP1_3695 1155 954 The target gene or bacterial strains studied in this study are mentioned in bold . Genetic analysis of wbbY and...”

Bbr_0440 DUF4422 domain-containing protein from Bifidobacterium breve UCC2003
Aligns to 4:227 / 276 (81.2%), covers 99.6% of PF14393, 233.3 bits

• Comparative genomics and genotype-phenotype associations in Bifidobacterium breve
  Bottacini, Scientific reports 2018
  • “...al . 55 Bbr_0439 Capsular polysaccharide biosynthesis protein X PF05704 Fanning et al . 55 Bbr_0440 Polysaccharide biosynthesis protein X PF14393 Fanning et al . 55 Bbr_0447 Conserved hypothetical protein PF04230 Fanning et al . 55 Bbr_0449 Hypothetical membrane spanning protein No hit Fanning et al...”

Q1G8E9 EpsIH, Putative glycosyltransferase from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Aligns to 11:222 / 267 (79.4%), covers 99.1% of PF14393, 220.5 bits

• Effects of ccpA gene deficiency in Lactobacillus delbrueckii subsp. bulgaricus under aerobic conditions as assessed by proteomic analysis
  Zhang, Microbial cell factories 2020
  • “...transport and metabolism A0A061BX52 EpsIIH, glycosyltransferase 42.16 18.01 1.802 Q1G8F3 EpsIM, glycosyltransferase 40.55 24.17 1.744 Q1G8E9 EpsIH, glycosyltransferase 31.48 28.09 1.624 Q1G7Z6 Pyruvate oxidase 67.67 64.94 1.592 Q1G8E8 EpsIG, glycosyltransferase 19.19 38.92 1.529 Q1GAY6 Acetate kinase 43.16 46.08 1.512 Q71HT0 Phosphopyruvate hydratase 15.15 82.19 1.520 A0A061BLT3...”

CJM1_1382 DUF4422 domain-containing protein from Campylobacter jejuni subsp. jejuni M1
Aligns to 382:632 / 978 (25.7%), covers 98.7% of PF14393, 211.1 bits

• Genomic characterization of Campylobacter jejuni strain M1
  Friis, PloS one 2010
  • “...CJM1_0138, CJM1_0278 , CJM1_0414, CJM1_0728, CJM1_0745 , CJM1_1118, CJM1_1119, CJM1_1120, CJM1_1372, CJM1_1373, CJM1_1375 , CJM1_1381, CJM1_1382 C8J_0035, C8J_0036, C8J_0063, C8J_0132, C8J_0133 , C8J_0154, C8J_0265, C8J_0266, C8J_0267, C8J_0272, C8J_0273, C8J_0274 , C8J_0275, C8J_0321, C8J_0529, C8J_0651, C8J_0776, C8J_0852, C8J_0918, C8J_1080, C8J_1081, C8J_1083, C8J_1329, C8J_1330, C8J_0131, C8J_1332, C8J_1334, C8J_1335,...”

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