Family Search for PF14688 (DUF4461)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF14688 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

Q8N3R3 T-cell activation inhibitor, mitochondrial from Homo sapiens
NP_001269842 T-cell activation inhibitor, mitochondrial isoform 1 from Homo sapiens
Aligns to 188:490 / 496 (61.1%), covers 100.0% of PF14688, 436.3 bits

• Data on the impact of the blood sample collection methods on blood protein profiling studies.
  Ilies, Data in brief 2017
  • “...11649 0.48 Q9P219 DAPLE Protein Daple Leakage 7162 10200 14709 10857 11183 10820 10822 0.22 Q8N3R3 TCAIM T-cell activation inhibitor, mitochondrial Leakage 13138 11101 8965 8622 9601 8057 9914 0.19 Q7LG56 RIR2B Ribonucleoside-diphosphate reductase subunit M2 B Leakage 5452 8109 8708 10250 8552 9235 8384 0.19...”
• Altered blood proteome in girls with high urine concentrations of bisphenol a, genistein, mono-ethyl hexylphthalate and mono-benzyl phthalate.
  Wang, MOJ proteomics & bioinformatics 2015
  • “...2 2.79 1.46 Q7Z5N4 sidekick 0.83 3 2.31 1.68 Q9P2W9 syntaxin-18 0.94 2 +2.31 1.32 Q8N3R3 T-Cell activation inhibitor 0.77 2 +4.56 1.51 O75643 U5 small nuclear ribonucleo 200 kDa helicase 0.97 4 2.11 1.19 Q61E27 vitellogenin-like 1 0.97 4 +2.48 1.73 Q81WG1 WD repeat-containing protein...”
• Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
  Hendrickson, PloS one 2010
  • GeneRIF: Observational study of gene-disease association. (HuGE Navigator)

TCAIM_MOUSE / Q66JZ4 T-cell activation inhibitor, mitochondrial; Tolerance associated gene-1 protein; TOAG-1 from Mus musculus (Mouse) (see 2 papers)
Aligns to 189:493 / 499 (61.1%), covers 100.0% of PF14688, 430.7 bits

• function: May regulate T-cell apoptosis

XP_006244255 T-cell activation inhibitor, mitochondrial isoform X1 from Rattus norvegicus
Aligns to 199:501 / 507 (59.8%), covers 100.0% of PF14688, 425.2 bits

• Identification of gene markers for the prediction of allograft rejection or permanent acceptance.
  Sawitzki, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007 (PubMed)
  • GeneRIF: Downregulation of TOAG-1 and alpha-1,2-mannosidase expression occurred in graft infiltrating cells and expression of both genes was also downregulated after T-cell activation in vitro.

TCAIM_RAT / P0DKR2 T-cell activation inhibitor, mitochondrial; Tolerance-associated gene-1; TOAG-1 from Rattus norvegicus (Rat) (see paper)
Aligns to 199:499 / 505 (59.6%), covers 100.0% of PF14688, 420.4 bits

• function: May regulate T-cell apoptosis.

CG2854 uncharacterized protein from Drosophila melanogaster
Aligns to 180:487 / 491 (62.7%), covers 99.7% of PF14688, 337.4 bits

• Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila
  Cheng, International journal of molecular sciences 2023
  • “...( CG43370 ), Ddx1 ( CG9054 ), l(1)G0196 ( CG14616 ), EfSec ( CG9841 ), CG2854 , CR45004 , MCU ( CG18769 ), disp ( CG2019 ), dos ( CG1044 ), Ugt37c1 ( CG8652 ), Pino ( CG4710 ), and Cap-D2 ( CG1911 ). These 19...”
• The Genomic Basis of Postponed Senescence in Drosophila melanogaster
  Carnes, PloS one 2015
  • “...P450-4d1 ( Cyp4d1 ), silver ( svr ), female sterile (1) Nasrat ( fs(1)N ), CG2854 , CG13868 , CG6428 , CG7713 , Centaurin gamma 1A ( CenG1A ) and CG33307 in males. This study represents the first biological functional annotation for the majority of these...”
• Molecular evolution and functional characterization of Drosophila insulin-like peptides
  Grönke, PLoS genetics 2010
  • “...at least 14 kb of genomic sequence including 5 annotated genes: dilp6 , CG33218 , CG2854 , CG14050 , CG34052 . Backcrossing and Wolbachia dilp mutants were backcrossed for at least ten generations into two different wild-type stocks, the inbred lab strain w 1118 and the...”
• A Drosophila insulin-like peptide promotes growth during nonfeeding states
  Slaidina, Developmental cell 2009
  • “...of the dilp6 gene. Deletion allele DILP6 #68 removes DILP6 and fouradjacent nonannotated genes: CG33218, CG2854, CG14050, and CG34052. (B) DILP6 loss of function were analyzed using either the two DILP6 mutant alleles, DILP6 #41 and DILP6 #68 , at 25C, or by silencing of DILP6...”
• From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies
  Benos, Genome research 2001
  • “...CG3443 CG3228 CG3218 CG3206 CG3193 CG3191 CG3078 CG3071 CG2924 CG2918 CG2879 CG2865 CG14050 CG2854 CG2845 A B+ C+ D* 0 0 0 A+ 0 0 0 0 A 0 0 0 B A D 0 0 B 0...”

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