Family Search for PF14924 (DUF4497)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF14924 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

MAP10_HUMAN / Q9P2G4 Microtubule-associated protein 10; Microtubule regulator of 120 KDa from Homo sapiens (Human) (see paper)
NP_061963 microtubule-associated protein 10 from Homo sapiens
Aligns to 86:190 / 905 (11.6%), covers 98.2% of PF14924, 86.0 bits

• function: Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis.
  subunit: Interacts (via middle region) with microtubules.
• Comprehensive study of altered proteomic landscape in proximal renal tubular epithelial cells in response to calcium oxalate monohydrate crystals
  Wang, BMC urology 2020
  • “...sapiens GN=MYL12A PE=1 SV=1 MYH14 Q7Z406 0.55 0.002 Myosin-14 OS=Homo sapiens GN=MYH14 PE=1 SV=2 MAP10 Q9P2G4 0.55 0.017 Microtubule-associated protein 10 OS=Homo sapiens GN=MAP10 PE=1 SV=2 PADI2 Q9Y2J8 0.54 0.012 Protein-arginine deiminase type-2 OS=Homo sapiens GN=PADI2 PE=1 SV=2 C14orf1 Q9UKR5 0.54 0.003 Probable ergosterol biosynthetic protein...”
• MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
  Fong, Journal of cell science 2013
  • GeneRIF: these data suggest that MTR120 is a novel microtubule (MT)-associated protein that directly stabilizes MTs and hence ensures the fidelity of cell division.

LOC105665898 uncharacterized protein LOC105665898 from Bombus terrestris
Aligns to 109:217 / 435 (25.1%), covers 97.3% of PF14924, 55.2 bits

• Diesel exhaust particles alter gut microbiome and gene expression in the bumblebee Bombus terrestris
  Seidenath, Ecology and evolution 2023
  • “...Cyclindependent kinase inhibitor 1C 1.832 1.175 0.029 LOC100650340 1.829 0.412 <0.001 LOC100647929 1.794 0.292 <0.001 LOC105665898 Uncharacterized protein LOC105665898 1.790 1.126 0.002 LOC105665941 Uncharacterized protein LOC105665941 1.781 1.785 <0.001 LOC100646677 1.774 9.275 <0.001 LOC110120139 Uncharacterized protein LOC110120139 1.759 0.166 <0.001 LOC100645840 1.739 0.876 <0.001 LOC100647883 1.738...”

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