Family Search for PF15378 (DUF4605)

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PF15378 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

Q9D882 Protein FAM241B from Mus musculus
Aligns to 61:119 / 120 (49.2%), covers 100.0% of PF15378, 92.7 bits

• Tandem mass tag-based quantitative proteomic analysis of effects of multiple sevoflurane exposures on the cerebral cortex of neonatal and adult mice.
  Feng, Frontiers in neurology 2022

F241B_HUMAN / Q96D05 Protein FAM241B from Homo sapiens (Human) (see paper)
XP_005269665 protein FAM241B isoform X2 from Homo sapiens
Aligns to 62:120 / 121 (48.8%), covers 100.0% of PF15378, 90.5 bits

• function: May play a role in lysosome homeostasis.
• A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
  Grupe, American journal of human genetics 2006
  • GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
• Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  Rose, Molecular medicine (Cambridge, Mass.)
  • GeneRIF: Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
• Brain Proteomic Profiling in Intractable Epilepsy Caused by TSC1 Truncating Mutations: A Small Sample Study.
  Liu, Frontiers in neurology 2020
  • “...P16389 Potassium voltage-gated channel subfamily A member 2 (KCNA2) 0.045913807 1.71 Cell membrane/Cell projection/Cell junction Q96D05 Uncharacterized protein FAM241B (FAM241B) 0.027804687 1.7 Membrane Q99707 Methionine synthase (MTR) 0.01578569 1.7 Cytoplasm O94817 Ubiquitin-like protein ATG12 (ATG12) 0.012333544 1.66 Cytoplasm/Preautophagosomal structure membrane Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein...”

NP_689613 uncharacterized protein FAM241A from Homo sapiens
Q8N8J7 Uncharacterized protein FAM241A from Homo sapiens
Aligns to 73:131 / 132 (44.7%), covers 100.0% of PF15378, 88.1 bits

• Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein
  Jun, BMB reports 2014
  • “...XP_002663002); Aplysia, Aplysia californica (NCBI Accession Number: XP_005096219). C4orf32: Human, Homo sapience (NCBI Accession Number: NP_689613); Mouse, Mus musculus (NCBI Accession Number: EDL12251); Zebrafish, Danio rerio (NCBI Accession Number: NP_001018611); Bovine, Bos taurus (NCBI Accession Number: NP_001070429). (B) The expression of human C4orf32 and C4orf52 transcript...”
• Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.
  Gupta, PloS one 2013
  • GeneRIF: Data indicate associations of SNPs in eight loci CXCR4, HHEX, FOXA2, NGN3, TCF7L2, FLJ39370 (C4orf32), LOC646279 (RPL21P7) and THADA with body mass index (BMI) and weight.
• A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
  Kalsi, Human molecular genetics 2010
  • GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
• Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry.
  Cornelis, Annals of internal medicine 2009
  • GeneRIF: Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
• Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study).
  Hertel, Diabetologia 2008 (PubMed)
  • GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
• Quantification of FAM20A in human milk and identification of calcium metabolism proteins
  Patel, Physiological reports 2021
  • “...mitochondrial [C1QBP_HUMAN] MFGM CID C2orf88 Q9BSF0 Small membrane Akinase anchor protein [SMAKA_HUMAN] MFGM CID C4orf32 Q8N8J7 Uncharacterized protein C4orf32 [CD032_HUMAN] MFGM CID CALCB P10092 Calcitonin generelated peptide 2 [CALCB_HUMAN] MFGM CID CASP1 P29466 Caspase1 [CASP1_HUMAN] MFGM CID CCDC124 Q96CT7 Coiledcoil domaincontaining protein 124 [CC124_HUMAN] MFGM CID...”

NP_001018611 uncharacterized protein C4orf32 homolog from Danio rerio
Aligns to 78:136 / 137 (43.1%), covers 100.0% of PF15378, 84.6 bits

• Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein
  Jun, BMB reports 2014
  • “...Number: NP_689613); Mouse, Mus musculus (NCBI Accession Number: EDL12251); Zebrafish, Danio rerio (NCBI Accession Number: NP_001018611); Bovine, Bos taurus (NCBI Accession Number: NP_001070429). (B) The expression of human C4orf32 and C4orf52 transcript in HeLa cells. mRNA expression of C4orf32 and C4orf52 were examined by RT-PCR in...”

NP_001070429 uncharacterized protein FAM241A from Bos taurus
Aligns to 79:137 / 138 (42.8%), covers 100.0% of PF15378, 82.6 bits

• Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein
  Jun, BMB reports 2014
  • “...Number: EDL12251); Zebrafish, Danio rerio (NCBI Accession Number: NP_001018611); Bovine, Bos taurus (NCBI Accession Number: NP_001070429). (B) The expression of human C4orf32 and C4orf52 transcript in HeLa cells. mRNA expression of C4orf32 and C4orf52 were examined by RT-PCR in HeLa cells. Each PCR band (*) was...”

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