Family Search for PF15764 (DUF4693)

PF15764 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

NP_079384 tubulin epsilon and delta complex protein 2 from Homo sapiens
Aligns to 148:431 / 433 (65.6%), covers 100.0% of PF15764, 511.8 bits

• TEDC2 plays an oncogenic role and serves as a therapeutic target of hepatocellular carcinoma.
  Li, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 (PubMed)
  • GeneRIF: TEDC2 plays an oncogenic role and serves as a therapeutic target of hepatocellular carcinoma.
• TEDC2 correlated with prognosis and immune microenvironment in lung adenocarcinoma.
  Fang, Scientific reports 2023
  • GeneRIF: TEDC2 correlated with prognosis and immune microenvironment in lung adenocarcinoma.
• A pan-cancer analysis of the prognostic implication and oncogenic role of tubulin epsilon and delta complex 2 (TEDC2) in human tumors.
  Liu, Frontiers in immunology 2023
  • GeneRIF: A pan-cancer analysis of the prognostic implication and oncogenic role of tubulin epsilon and delta complex 2 (TEDC2) in human tumors.

TEDC2_MOUSE / Q6GQV0 Tubulin epsilon and delta complex protein 2 from Mus musculus (Mouse) (see paper)
Aligns to 150:434 / 436 (65.4%), covers 100.0% of PF15764, 499.2 bits

• function: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability.
  subunit: Interacts with TEDC1 (PubMed:29459677). Found in a complex with TEDC1, TEDC2, TUBE1 and TUBD1 (PubMed:29459677).

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