Family Search for PF16335 (DUF4965)
PF16335 hits 18 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
S7S113 Glutaminase GtaA from Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617)
Aligns to 340:519 / 693 (26.0%), covers 99.4% of PF16335, 275.3 bits
GTAA_ASPOR / Q2U4L7 Glutaminase A; EC 3.5.1.2 from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
Aligns to 341:512 / 690 (24.9%), covers 99.4% of PF16335, 275.2 bits
- function: Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. Catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine.
catalytic activity: H2O + L-glutamine = L-glutamate + NH4(+) (RHEA:15889)
An02g13750 uncharacterized protein from Aspergillus niger
Aligns to 339:510 / 691 (24.9%), covers 99.4% of PF16335, 272.1 bits
K9GD10 Glutaminase GtaA from Penicillium digitatum (strain PHI26 / CECT 20796)
Aligns to 230:401 / 579 (29.7%), covers 99.4% of PF16335, 272.1 bits
AFUA_3G07030, Afu3g07030 glutaminase GtaA from Aspergillus fumigatus Af293
Aligns to 339:510 / 691 (24.9%), covers 99.4% of PF16335, 271.2 bits
- The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence
Bom, Eukaryotic cell 2015 - “...in the WT Afu1g15730 Afu1g14450 Afu3g07030 Afu3g00590 Afu1g05770 Afu1g10970 Afu6g14470 Afu2g00967 Afu6g03210 Afu8g00630 Afu4g09280 Afu4g11800 Afu6g12070...”
- Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus
Beauvais, PLoS pathogens 2013 - “...13.4 AFUA_2G03510 Putative pheromone processing carboxypeptidase Sxa2 49.75 AFUA_8G04120 Secreted serine carboxypeptidase S1 SCP1 61.28 AFUA_3G07030 Putative secreted glutaminase GtaA 76.15 AFUA_2G12630 allergenic cerato-platanin Aspf13, serine alkaline protease ASPF13 15.94 AFUA_5G02330 allergenic restrictocin, mitogilin Aspf1 ASPF1 19.59 AFUA_4G03660 Putative acid phosphatase, PhoB regulated 46.1 AFUA_5G09240 Cu,Zn...”
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...Afu5g02850 20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420, Afu8g06100,...”
- A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus
Willger, PLoS pathogens 2008 - “...12.92 AFUA_8g00190 cytochrome P450, putative 11.40 AFUA_1g16250 alpha-glucosidase B 9.95 AFUA_3g12960 cytochrome P450, putative 8.97 AFUA_3g07030 glutaminase A 8.24 AFUA_8g00620 dimethylallyl tryptophan synthase, putative 7.65 AFUA_4g09980 cytochrome P450 monooxygenase, putative 7.15 OTHER AND UNKNOWN GENES AFUA_6g03680 hypothetical protein 13.55 AFUA_3g07870 conserved hypothetical protein 13.23 AFUA_8g04380 conserved...”
SS1G_08889 hypothetical protein from Sclerotinia sclerotiorum 1980 UF-70
Aligns to 349:520 / 738 (23.3%), covers 100.0% of PF16335, 257.8 bits
- ε-poly-L-lysine Affects the Vegetative Growth, Pathogenicity and Expression Regulation of Necrotrophic Pathogen Sclerotinia sclerotiorum and Botrytis cinerea
Zhou, Journal of fungi (Basel, Switzerland) 2021 - “...SsAmy3 , SS1G_13472), meiotic activator RIM4 ( SsRIM4 , SS1G_03997), glutaminase A ( SsGtaA , SS1G_08889 and BcGtaA , BC1G_10486) were reduced in S. sclerotiorum or B. cinerea treated by -PL ( Figure 6 a). Specifically, the expression levels of the ribosomal export protein NMD3 (BC1G_03554)...”
- “...meiosis [ 40 ] SS1G_13472 alpha-amylase A amy3 0.68 down starch metabolism [ 41 ] SS1G_08889 glutaminase A 1.65 down glutamic acid synthesis [ 42 ] BC1G_10486 glutaminase A 1.11 down glutamic acid synthesis [ 42 ] BC1G_03554 ribosomal export protein NMD3 1.02 up mRNA and...”
- Proteomics research and related functional classification of liquid sclerotial exudates of Sclerotinia ginseng
Wang, PeerJ 2017 - “...protein SS1G_05898 36 89,774 4 (1) 1 (1) 0.04 Amino Acid Metabolism gi|154693286| hypothetical protein SS1G_08889 525 81,000 37 (23) 11 (9) 0.74 gi|154691589| hypothetical protein SS1G_00730 78 66,638 10 (6) 4 (2) 0.1 Protein binding gi|1095454060| hypothetical protein sscle_07g057880 42 42,363 2 (1) 1 (1)...”
- An Interspecies Comparative Analysis of the Predicted Secretomes of the Necrotrophic Plant Pathogens Sclerotinia sclerotiorum and Botrytis cinerea
Heard, PloS one 2015 - “...glycoside hydrolase family 61 protein C023 SS1G_07836 HP similar to acidic protease SS1G_07837 PP C024 SS1G_08889 glutaminase SS1G_08892 PP SS1G_08894 alpha beta-hydrolase C025 SS1G_09129 6-phospho-beta-galactosidase SS1G_09130 CHP C026 SS1G_09248 hydrophobin SS1G_09250 iron-sulfur cluster-binding rieske family domain protein SS1G_09251 HP similar to endoglucanase II C027 SS1G_09363 -...”
TRIATDRAFT_129231 uncharacterized protein from Trichoderma atroviride
Aligns to 341:511 / 689 (24.8%), covers 100.0% of PF16335, 256.7 bits
G2QFL3 Glutaminase GtaA from Thermothelomyces thermophilus (strain ATCC 42464 / BCRC 31852 / DSM 1799)
Aligns to 337:507 / 686 (24.9%), covers 99.4% of PF16335, 256.7 bits
- Quantitative comparison of the biomass-degrading enzyme repertoires of five filamentous fungi.
Arntzen, Scientific reports 2020 - “...extracellular exoglucanases 40 . Thus, DUF1996 may be associated with polysaccharide degradation. The other protein, G2QFL3, had four unknown domains, DUF4964, DUF5127, DUF4965 and DUF1793 (Pfam: PF16334, PF17168, PF16335 and PF08760, respectively), where two of the domains seem to be part of a GH superfamily according...”
NCU03861 glutaminase A from Neurospora crassa OR74A
Aligns to 344:514 / 692 (24.7%), covers 99.4% of PF16335, 254.5 bits
WP_074995790 glutaminase family protein from Streptomyces misionensis
Aligns to 402:576 / 752 (23.3%), covers 100.0% of PF16335, 239.1 bits
- Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
Schmerling, Communications biology 2022 - “...41.7Umg 1 protein and a K M of 0.67mM. b Substrate specificity of Phchr2|2915237 and WP_074995790 from S. misionensis . The activity with different p- nitrophenol-based substrates was determined by measuring the release of p NP. The activity on complex polysaccharides was determined via the DNSA...”
- “...displayed the highest activities with p NP-Glc, p NP-Xyl, lichenan, and beech wood xylan, while WP_074995790, a close homolog of Phchr2|3002168 showed activity only with p NP-Gal as a substrate with a specific activity of 0.85Umg 1 protein. c Kinetic characterization of Phchr2|2915237 using p NP-Glc,...”
Afu6g09910 glutaminase, putative from Aspergillus fumigatus Af293
Aligns to 335:511 / 721 (24.5%), covers 99.4% of PF16335, 237.8 bits
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420, Afu8g06100, Afu8g06590...”
UMAG_06158 putative glutaminase A from Ustilago maydis 521
Aligns to 491:672 / 912 (20.0%), covers 99.4% of PF16335, 237.6 bits
An11g07960 uncharacterized protein from Aspergillus niger
Aligns to 334:510 / 722 (24.5%), covers 99.4% of PF16335, 237.3 bits
R1GV87 Putative glutaminase protein from Botryosphaeria parva (strain UCR-NP2)
Aligns to 425:609 / 854 (21.7%), covers 98.9% of PF16335, 236.8 bits
- Unveiling the Secretome of the Fungal Plant Pathogen Neofusicoccum parvum Induced by In Vitro Host Mimicry.
Nazar, Journal of fungi (Basel, Switzerland) 2022 - “...R1FZX2, and R1H1L9), proteinprotein interactions (R1ENG6, R1E9S0, and R1GCJ5), and proteins with other functions (R1EGT1, R1GV87, R1EAF3, R1G1U2, R1FV21, R1FVG4, R1GBA7, R1EWZ5, R1GDV3, R1GKT0, R1E681)were also identified ( Figure 1 and Table 2 ). 3.2. ProteinProtein Interaction Due to the lack of data available on the...”
- “...beta hydrolase protein R1EGT1 2.7 3.692 11 3.31 10 9 118.1 Extracellular Putative glutaminase protein R1GV87 2.7 3.603 10 1.15 10 9 215.65 Extracellular Putative fasciclin domain family protein R1EWZ5 2 2.878 12 2.37 10 9 129.86 Extracellular Uncharacterized protein R1GDV3 4.1 2.108 5 3.67 10...”
C1FYE6 Glutaminase from Paracoccidioides brasiliensis (strain Pb18)
2 alignments in 364:585 / 903 (20.2%), covering up to 71.8% of PF16335, 215.1 bits
- Extracellular vesicles from virulent P. brasiliensis induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response
Montanari, Virulence 2024 - “...3,898842 8,58E05 C1G6P2 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase UP(D) 3,82139 4,39E05 C1G0F9 kynureninase [EC:3.7.1.3] UP(D) 3,62137 9,06E05 C1FYE6 Glutaminase A UP(D) 3,433912 0,000121 Lipid metabolism C1GDH4 leukotriene-A4 hydrolase [EC:3.3.2.6] UP(D) 4,263176 0,000274 C1GMW7 Sphingolipid C9-methyltransferase A UP (8S) 3,572532 0,037729 C1G0P4 long-chain acyl-CoA synthetase [EC:6.2.1.3] UP (12S) 3,064416...”
AFUA_3G10910, Afu3g10910 glutaminase, putative from Aspergillus fumigatus Af293
B0XXQ4 Glutaminase, putative from Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
2 alignments in 351:577 / 834 (23.0%), covering up to 71.3% of PF16335, 212.9 bits
- At the metal-metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin
Traynor, Microbiology (Reading, England) 2021 - “...46.7 AFUA_5G14330 Thioredoxin reductase 3.27287 0.001762 21 74 AFUA_4G12990 Glutaminase, putative 3.06718 0.000768 18 28.9 AFUA_3G10910 NADH-dependent flavin oxidoreductase, putative 2.72911 0.001482 21 53.8 AFUA_7G06420 Catalase B CatB/1 2.66263 0.003534 98 76.8 AFUA_3G02270 Oxidoreductase, short-chain dehydrogenase/reductase family 2.40285 0.003956 5 34.3 AFUA_4G03680 Homocysteine synthase CysD 1.97439...”
- Assembly and disassembly of Aspergillus fumigatus conidial rodlets
Valsecchi, Cell surface (Amsterdam, Netherlands) 2019 - “...AFUA_6G00160 B0YDZ9 Ser/Thr protein phosphatase family protein Yes 0.73 23.90 666 75.547 565267 4.7 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 548343 6.0 AFUB_080680 AFUA_8G07120 B0Y9D8 Beta-1,6-glucanase, putative No 0.55 23.60 488 51.430 533200 2.7 AFUB_024700 AFUA_2G08790 B0XRS8 Putative metallocarboxypeptidase ecm14 Yes 0.95...”
- “...AFUB_045170 AFUA_3G03060 B0Y004 Cell wall protein phiA No 0.58 37.80 185 19.380 2437133 3.0 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 2213600 12.3 AFUB_087640 AFUA_7G01060 B0YBS2 Cysteine-rich secreted protein No 0.81 22.40 343 36.860 2169400 3.7 AFUB_072730 AFUA_6G06800 B0Y766 Probable carboxypeptidase Yes 0.58...”
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...Afu1g12190, Afu5g02850 20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420,...”
- Assembly and disassembly of Aspergillus fumigatus conidial rodlets
Valsecchi, Cell surface (Amsterdam, Netherlands) 2019 - “...B0YDZ9 Ser/Thr protein phosphatase family protein Yes 0.73 23.90 666 75.547 565267 4.7 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 548343 6.0 AFUB_080680 AFUA_8G07120 B0Y9D8 Beta-1,6-glucanase, putative No 0.55 23.60 488 51.430 533200 2.7 AFUB_024700 AFUA_2G08790 B0XRS8 Putative metallocarboxypeptidase ecm14 Yes 0.95 6.70...”
- “...AFUA_3G03060 B0Y004 Cell wall protein phiA No 0.58 37.80 185 19.380 2437133 3.0 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 2213600 12.3 AFUB_087640 AFUA_7G01060 B0YBS2 Cysteine-rich secreted protein No 0.81 22.40 343 36.860 2169400 3.7 AFUB_072730 AFUA_6G06800 B0Y766 Probable carboxypeptidase Yes 0.58 25.90...”
G4N1P6 Glutaminase GtaA from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
MGG_07512 glutaminase GtaA from Pyricularia oryzae 70-15
2 alignments in 353:572 / 828 (22.8%), covering up to 72.4% of PF16335, 207.4 bits
GTAA_ARTBC / D4AMT2 Probable glutaminase ARB_05535/05536; EC 3.5.1.2 from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see paper)
2 alignments in 354:581 / 862 (20.5%), covering up to 70.7% of PF16335, 207.0 bits
- function: Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism (By similarity).
catalytic activity: H2O + L-glutamine = L-glutamate + NH4(+) (RHEA:15889)
Or search for genetic data about PF16335 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory