Family Search for PF16335 (GtaA_6_Hairpin)
PF16335 hits 19 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
GTAA_ASPOR / Q2U4L7 Glutaminase A; EC 3.5.1.2 from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
Aligns to 343:688 / 690 (50.1%), covers 100.0% of PF16335, 525.3 bits
- function: Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. Catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine.
catalytic activity: L-glutamine + H2O = L-glutamate + NH4(+) (RHEA:15889)
S7S113 Glutaminase GtaA from Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617)
Aligns to 342:691 / 693 (50.5%), covers 100.0% of PF16335, 522.0 bits
K9GD10 Glutaminase GtaA from Penicillium digitatum (strain PHI26 / CECT 20796)
Aligns to 232:576 / 579 (59.6%), covers 99.7% of PF16335, 521.7 bits
AFUA_3G07030, Afu3g07030 glutaminase GtaA from Aspergillus fumigatus Af293
Aligns to 341:685 / 691 (49.9%), covers 100.0% of PF16335, 518.9 bits
- The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence
Bom, Eukaryotic cell 2015 - “...in the WT Afu1g15730 Afu1g14450 Afu3g07030 Afu3g00590 Afu1g05770 Afu1g10970 Afu6g14470 Afu2g00967 Afu6g03210 Afu8g00630 Afu4g09280 Afu4g11800 Afu6g12070...”
- Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus
Beauvais, PLoS pathogens 2013 - “...13.4 AFUA_2G03510 Putative pheromone processing carboxypeptidase Sxa2 49.75 AFUA_8G04120 Secreted serine carboxypeptidase S1 SCP1 61.28 AFUA_3G07030 Putative secreted glutaminase GtaA 76.15 AFUA_2G12630 allergenic cerato-platanin Aspf13, serine alkaline protease ASPF13 15.94 AFUA_5G02330 allergenic restrictocin, mitogilin Aspf1 ASPF1 19.59 AFUA_4G03660 Putative acid phosphatase, PhoB regulated 46.1 AFUA_5G09240 Cu,Zn...”
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...Afu5g02850 20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420, Afu8g06100,...”
- A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus
Willger, PLoS pathogens 2008 - “...12.92 AFUA_8g00190 cytochrome P450, putative 11.40 AFUA_1g16250 alpha-glucosidase B 9.95 AFUA_3g12960 cytochrome P450, putative 8.97 AFUA_3g07030 glutaminase A 8.24 AFUA_8g00620 dimethylallyl tryptophan synthase, putative 7.65 AFUA_4g09980 cytochrome P450 monooxygenase, putative 7.15 OTHER AND UNKNOWN GENES AFUA_6g03680 hypothetical protein 13.55 AFUA_3g07870 conserved hypothetical protein 13.23 AFUA_8g04380 conserved...”
An02g13750 uncharacterized protein from Aspergillus niger
Aligns to 341:685 / 691 (49.9%), covers 100.0% of PF16335, 512.9 bits
G2QFL3 Glutaminase GtaA from Thermothelomyces thermophilus (strain ATCC 42464 / BCRC 31852 / DSM 1799)
Aligns to 339:681 / 686 (50.0%), covers 100.0% of PF16335, 494.7 bits
- Quantitative comparison of the biomass-degrading enzyme repertoires of five filamentous fungi.
Arntzen, Scientific reports 2020 - “...extracellular exoglucanases 40 . Thus, DUF1996 may be associated with polysaccharide degradation. The other protein, G2QFL3, had four unknown domains, DUF4964, DUF5127, DUF4965 and DUF1793 (Pfam: PF16334, PF17168, PF16335 and PF08760, respectively), where two of the domains seem to be part of a GH superfamily according...”
TRIATDRAFT_129231 uncharacterized protein from Trichoderma atroviride
Aligns to 343:686 / 689 (49.9%), covers 100.0% of PF16335, 491.8 bits
SS1G_08889 hypothetical protein from Sclerotinia sclerotiorum 1980 UF-70
Aligns to 351:697 / 738 (47.0%), covers 100.0% of PF16335, 490.7 bits
- ε-poly-L-lysine Affects the Vegetative Growth, Pathogenicity and Expression Regulation of Necrotrophic Pathogen Sclerotinia sclerotiorum and Botrytis cinerea
Zhou, Journal of fungi (Basel, Switzerland) 2021 - “...SsAmy3 , SS1G_13472), meiotic activator RIM4 ( SsRIM4 , SS1G_03997), glutaminase A ( SsGtaA , SS1G_08889 and BcGtaA , BC1G_10486) were reduced in S. sclerotiorum or B. cinerea treated by -PL ( Figure 6 a). Specifically, the expression levels of the ribosomal export protein NMD3 (BC1G_03554)...”
- “...meiosis [ 40 ] SS1G_13472 alpha-amylase A amy3 0.68 down starch metabolism [ 41 ] SS1G_08889 glutaminase A 1.65 down glutamic acid synthesis [ 42 ] BC1G_10486 glutaminase A 1.11 down glutamic acid synthesis [ 42 ] BC1G_03554 ribosomal export protein NMD3 1.02 up mRNA and...”
- Proteomics research and related functional classification of liquid sclerotial exudates of Sclerotinia ginseng
Wang, PeerJ 2017 - “...protein SS1G_05898 36 89,774 4 (1) 1 (1) 0.04 Amino Acid Metabolism gi|154693286| hypothetical protein SS1G_08889 525 81,000 37 (23) 11 (9) 0.74 gi|154691589| hypothetical protein SS1G_00730 78 66,638 10 (6) 4 (2) 0.1 Protein binding gi|1095454060| hypothetical protein sscle_07g057880 42 42,363 2 (1) 1 (1)...”
- An Interspecies Comparative Analysis of the Predicted Secretomes of the Necrotrophic Plant Pathogens Sclerotinia sclerotiorum and Botrytis cinerea
Heard, PloS one 2015 - “...glycoside hydrolase family 61 protein C023 SS1G_07836 HP similar to acidic protease SS1G_07837 PP C024 SS1G_08889 glutaminase SS1G_08892 PP SS1G_08894 alpha beta-hydrolase C025 SS1G_09129 6-phospho-beta-galactosidase SS1G_09130 CHP C026 SS1G_09248 hydrophobin SS1G_09250 iron-sulfur cluster-binding rieske family domain protein SS1G_09251 HP similar to endoglucanase II C027 SS1G_09363 -...”
WP_074995790 glutaminase family protein from Streptomyces misionensis
Aligns to 404:748 / 752 (45.9%), covers 100.0% of PF16335, 487.2 bits
- Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
Schmerling, Communications biology 2022 - “...41.7Umg 1 protein and a K M of 0.67mM. b Substrate specificity of Phchr2|2915237 and WP_074995790 from S. misionensis . The activity with different p- nitrophenol-based substrates was determined by measuring the release of p NP. The activity on complex polysaccharides was determined via the DNSA...”
- “...displayed the highest activities with p NP-Glc, p NP-Xyl, lichenan, and beech wood xylan, while WP_074995790, a close homolog of Phchr2|3002168 showed activity only with p NP-Gal as a substrate with a specific activity of 0.85Umg 1 protein. c Kinetic characterization of Phchr2|2915237 using p NP-Glc,...”
NCU03861 glutaminase A from Neurospora crassa OR74A
Aligns to 346:688 / 692 (49.6%), covers 100.0% of PF16335, 485.3 bits
BF9343_0291 glutaminase domain-containing protein from Bacteroides fragilis NCTC 9343
Aligns to 482:819 / 826 (40.9%), covers 99.7% of PF16335, 471.3 bits
- Multi-omics approach for understanding the response of Bacteroides fragilis to carbapenems
Zholdybayeva, Heliyon 2024 - “...2,71E+00 unknown function BF9343_1393 Bacteriophage-related replication protein (BF9343_1393) 5,05E+00 BF9343_2497 DUF169 domain-containing protein (I6J55_RS01150) 8,11E-01 BF9343_0291 Exported glutaminase (BF9343_0291) 1,02E+00 BF9343_0624 Lipoprotein (BF9343_0624) 2,88E+00 BF9343_3647 Liporotein (BF9343_3647) 5,07E+00 BF9343_3659 Membrane protein (BF9343_3659) 2,92E+00 BF9343_1783 Putative lipoprotein (BF9343_1783) 1,07E+00 BF9343_1767 Putative peptidase (BF9343_1767) 2,64E+00 BF9343_1640 TonB-dependent receptor...”
R1GV87 Putative glutaminase protein from Botryosphaeria parva (strain UCR-NP2)
Aligns to 427:785 / 854 (42.0%), covers 99.7% of PF16335, 442.1 bits
- Unveiling the Secretome of the Fungal Plant Pathogen Neofusicoccum parvum Induced by In Vitro Host Mimicry.
Nazar, Journal of fungi (Basel, Switzerland) 2022 - “...R1FZX2, and R1H1L9), proteinprotein interactions (R1ENG6, R1E9S0, and R1GCJ5), and proteins with other functions (R1EGT1, R1GV87, R1EAF3, R1G1U2, R1FV21, R1FVG4, R1GBA7, R1EWZ5, R1GDV3, R1GKT0, R1E681)were also identified ( Figure 1 and Table 2 ). 3.2. ProteinProtein Interaction Due to the lack of data available on the...”
- “...beta hydrolase protein R1EGT1 2.7 3.692 11 3.31 10 9 118.1 Extracellular Putative glutaminase protein R1GV87 2.7 3.603 10 1.15 10 9 215.65 Extracellular Putative fasciclin domain family protein R1EWZ5 2 2.878 12 2.37 10 9 129.86 Extracellular Uncharacterized protein R1GDV3 4.1 2.108 5 3.67 10...”
Afu6g09910 glutaminase, putative from Aspergillus fumigatus Af293
Aligns to 337:684 / 721 (48.3%), covers 100.0% of PF16335, 435.6 bits
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420, Afu8g06100, Afu8g06590...”
An11g07960 uncharacterized protein from Aspergillus niger
Aligns to 336:683 / 722 (48.2%), covers 99.7% of PF16335, 426.8 bits
G4N1P6 Glutaminase GtaA from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
MGG_07512 glutaminase GtaA from Pyricularia oryzae 70-15
3 alignments in 355:785 / 828 (48.6%), covering up to 39.1% of PF16335, 408.9 bits
C1FYE6 Glutaminase from Paracoccidioides brasiliensis (strain Pb18)
3 alignments in 366:793 / 903 (40.6%), covering up to 35.6% of PF16335, 400.4 bits
- Extracellular vesicles from virulent P. brasiliensis induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response
Montanari, Virulence 2024 - “...3,898842 8,58E05 C1G6P2 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase UP(D) 3,82139 4,39E05 C1G0F9 kynureninase [EC:3.7.1.3] UP(D) 3,62137 9,06E05 C1FYE6 Glutaminase A UP(D) 3,433912 0,000121 Lipid metabolism C1GDH4 leukotriene-A4 hydrolase [EC:3.3.2.6] UP(D) 4,263176 0,000274 C1GMW7 Sphingolipid C9-methyltransferase A UP (8S) 3,572532 0,037729 C1G0P4 long-chain acyl-CoA synthetase [EC:6.2.1.3] UP (12S) 3,064416...”
B0XXQ4 Glutaminase, putative from Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
AFUA_3G10910, Afu3g10910 glutaminase, putative from Aspergillus fumigatus Af293
3 alignments in 353:778 / 834 (48.3%), covering up to 37.9% of PF16335, 399.3 bits
- Assembly and disassembly of Aspergillus fumigatus conidial rodlets
Valsecchi, Cell surface (Amsterdam, Netherlands) 2019 - “...B0YDZ9 Ser/Thr protein phosphatase family protein Yes 0.73 23.90 666 75.547 565267 4.7 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 548343 6.0 AFUB_080680 AFUA_8G07120 B0Y9D8 Beta-1,6-glucanase, putative No 0.55 23.60 488 51.430 533200 2.7 AFUB_024700 AFUA_2G08790 B0XRS8 Putative metallocarboxypeptidase ecm14 Yes 0.95 6.70...”
- “...AFUA_3G03060 B0Y004 Cell wall protein phiA No 0.58 37.80 185 19.380 2437133 3.0 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 2213600 12.3 AFUB_087640 AFUA_7G01060 B0YBS2 Cysteine-rich secreted protein No 0.81 22.40 343 36.860 2169400 3.7 AFUB_072730 AFUA_6G06800 B0Y766 Probable carboxypeptidase Yes 0.58 25.90...”
- At the metal-metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin
Traynor, Microbiology (Reading, England) 2021 - “...46.7 AFUA_5G14330 Thioredoxin reductase 3.27287 0.001762 21 74 AFUA_4G12990 Glutaminase, putative 3.06718 0.000768 18 28.9 AFUA_3G10910 NADH-dependent flavin oxidoreductase, putative 2.72911 0.001482 21 53.8 AFUA_7G06420 Catalase B CatB/1 2.66263 0.003534 98 76.8 AFUA_3G02270 Oxidoreductase, short-chain dehydrogenase/reductase family 2.40285 0.003956 5 34.3 AFUA_4G03680 Homocysteine synthase CysD 1.97439...”
- Assembly and disassembly of Aspergillus fumigatus conidial rodlets
Valsecchi, Cell surface (Amsterdam, Netherlands) 2019 - “...AFUA_6G00160 B0YDZ9 Ser/Thr protein phosphatase family protein Yes 0.73 23.90 666 75.547 565267 4.7 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 548343 6.0 AFUB_080680 AFUA_8G07120 B0Y9D8 Beta-1,6-glucanase, putative No 0.55 23.60 488 51.430 533200 2.7 AFUB_024700 AFUA_2G08790 B0XRS8 Putative metallocarboxypeptidase ecm14 Yes 0.95...”
- “...AFUB_045170 AFUA_3G03060 B0Y004 Cell wall protein phiA No 0.58 37.80 185 19.380 2437133 3.0 AFUB_038220 AFUA_3G10910 B0XXQ4 Glutaminase, putative Yes 0.65 17.90 834 92.757 2213600 12.3 AFUB_087640 AFUA_7G01060 B0YBS2 Cysteine-rich secreted protein No 0.81 22.40 343 36.860 2169400 3.7 AFUB_072730 AFUA_6G06800 B0Y766 Probable carboxypeptidase Yes 0.58...”
- Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus
Yang, Evolutionary bioinformatics online 2012 - “...Afu1g12190, Afu5g02850 20 4 Afu4g00730, Afu8g01530, Afu2g14320, Afu3g13130 21 3 Afu2g11270, Afu3g00910, Afu1g15440 22 3 Afu3g10910, Afu3g07030, Afu6g09910 23 3 Afu1g17570, Afu1g04870, Afu6g03200 24 3 Afu2g05880, Afu1g10930, Afu5g11020 25 3 Afu8g00770, Afu7g05550, Afu2g09450 26 3 Afu2g09520, Afu6g11600, Afu6g07480 27 3 Afu3g01170, Afu7g01590, Afu5g13810 28 3 Afu7g00420,...”
GTAA_ARTBC / D4AMT2 Probable glutaminase ARB_05535/05536; EC 3.5.1.2 from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see paper)
3 alignments in 356:782 / 862 (42.0%), covering up to 35.3% of PF16335, 392.1 bits
- function: Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism (By similarity).
catalytic activity: L-glutamine + H2O = L-glutamate + NH4(+) (RHEA:15889)
BT3481 putative glutaminase A from Bacteroides thetaiotaomicron VPI-5482
Aligns to 1:165 / 174 (94.8%), covers 48.4% of PF16335, 211.3 bits
Or search for genetic data about PF16335 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory