Family Search for PF17496 (DUF5431)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF17496 hits 3 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

FLMC1_ECOLI / P11519 Protein FlmC; F-plasmid maintenance protein C from Escherichia coli (strain K12) (see paper)
Aligns to 1:70 / 70 (100.0%), covers 100.0% of PF17496, 127.0 bits

• function: Component of a type I toxin-antitoxin (TA) system (Probable). Either this protein or sequences upstream of it are required for translation of downstream flmA; this could be translationally coupled to flmA (PubMed:3049248).
  disruption phenotype: A plasmid unable to express the start codon of this protein can be lost without detriment to the bacteria, when normally the plasmid is not lost due to the Flm plasmid maintenance system.

Or search for genetic data about PF17496 in the Fitness Browser