Family Search for PF19543 (GH123_N)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF19543 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

B2UQA1 Coagulation factor 5/8 type domain protein from Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)
Aligns to 190:342 / 712 (21.5%), covers 12.4% of PF19543, 38.7 bits

• The evolution and competitive strategies of Akkermansia muciniphila in gut
  Kim, Gut microbes 2022
  • “...1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 B2UQA1 Figure 3. Comparison of functional categories of Akkermansia muciniphila . The ordinate axis represents the percentages of genes in each functional category. The pan-genome from the 27 A. muciniphila genomes...”

5l7vA / A6L2E5 Crystal structure of bvgh123 with bond transition state analog galthiazoline. (see paper)
Aligns to 33:198 / 563 (29.5%), covers 12.6% of PF19543, 37.7 bits

• Ligand: (3ar,5r,6r,7r,7ar)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3ah-pyrano[3,2-d][1,3]thiazole-6,7-diol (5l7vA)

E9RH20 beta-N-acetylgalactosaminidase (EC 3.2.1.53) from Paenibacillus sp. (see paper)
BAJ83606.1 glycosphingolipid β-N-acetylgalactosaminidase (NgaP) (EC 3.2.1.53|3.2.1.-) (see protein)
Aligns to 281:446 / 1034 (16.1%), covers 13.7% of PF19543, 36.6 bits

ABG82546.1 glycolipid exo-β-N-acetylgalactosaminidase (CpNga123;CPF_1473) (EC 3.2.1.53|3.2.1.-) (see protein)
CPF_1473 hypothetical protein from Clostridium perfringens ATCC 13124
Aligns to 20:165 / 587 (24.9%), covers 11.4% of PF19543, 26.6 bits

• The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium perfringens
  Noach, Journal of molecular biology 2016 (PubMed)
  • “...from C. perfringens strain ATCC 13124 (locus tag CPF_1473) is a -N-acetylgalactosaminidase, similar to NgaP from Paenibacillus sp. TS12. Like NgaP, CpNga123 was...”
  • “...from C. perfringens strain ATCC 13124 (locus tag CPF_1473) is a - N -acetylgalactosaminidase, similar to NgaP from Paenibacillus sp. TS12. Like NgaP, CpNga123...”

5fqgA / A0A0H2YNR7 The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from clostridium perfringens (see paper)
Aligns to 16:161 / 583 (25.0%), covers 11.4% of PF19543, 26.6 bits

• Ligand: beta-d-galactopyranose (5fqgA)

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