Family Search for PF19585 (DUF6092)

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PF19585 hits 3 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

Ndas_1147 DUF6092 family protein from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111
Aligns to 13:97 / 105 (81.0%), covers 100.0% of PF19585, 106.3 bits

• Comparative studies on similarities and differences of cyclodipeptide oxidases for installation of C-C double bonds at the diketopiperazine ring
  Mikulski, Applied microbiology and biotechnology 2020
  • “...(Lautru et al. 2002 ). The second known CDO comprising the two subunits Ndas_1146 and Ndas_1147, also located together with a CDPS gene ndas_1148 , was identified in Nocardiopsis dassonvillei and was proven to be responsible for ,-dehydrogenation in the biosynthesis of the nocazine family (Giessen...”
  • “...the amino acid level. The sequence identities of the small subunit CDO-NpB with AlbB and Ndas_1147 were found to be 48 and 66%, respectively. It can therefore be expected that the holoenzyme CDO-Np also catalyzes the dehydrogenation of CDPs. The coding sequences of CDO-NpA and CDO-NpB...”

ALBB_STRNR / Q8GED8 Protein AlbB; Albonoursin synthase protein B from Streptomyces noursei (Streptomyces albulus) (see paper)
Aligns to 14:99 / 105 (81.9%), covers 100.0% of PF19585, 101.4 bits

• function: Involved in the biosynthesis of albonoursin (cyclo[(alpha,beta-dehydro-Phe)-(alpha,beta-dehydro-Leu)]), an antibacterial peptide. AlbB is essential for cyclic dipeptide oxidase AlbA (CDO) activity.

WP_026129216 DUF6092 family protein from Nocardiopsis sp. L17-MgMaSL7
Aligns to 12:97 / 105 (81.9%), covers 98.8% of PF19585, 100.4 bits

• Comparative studies on similarities and differences of cyclodipeptide oxidases for installation of C-C double bonds at the diketopiperazine ring
  Mikulski, Applied microbiology and biotechnology 2020
  • “...(accession number AAN0790 for AlbA and AAN07908 for AlbB) and CDO-Np (WP_017544373 for CDO-NpA and WP_026129216 for CDO-NpB) were amplified by using the primers listed in Table S1 . The amplified DNA fragments encoding AlbA/B and CDO-Np were cloned into the pGEM-T Easy vector (Promega, Mannheim,...”
  • “...signal. Results Sequence analysis of CDO-Np and comparison with known CDOs WP_017544373 for CDO-NpA and WP_026129216 for CDO-NpB from N. prasina comprise 185 and 105 amino acids, respectively. Their coding sequences overlap with each other by 20bps. Sequence comparison revealed that CDO-NpA shares a sequence identity...”

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