Family Search for PF19634 (DUF6137)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF19634 hits 1 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

BTRV_NIACI / Q4H4E3 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase BtrO; Butirosin biosynthesis protein V; EC 1.14.14.13 from Niallia circulans (Bacillus circulans) (see paper)
Aligns to 8:82 / 82 (91.5%), covers 78.0% of PF19634, 43.0 bits

• function: NAD(P)H:FMN oxidoreductase component of a two-component system involved in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Together with BtrO, mediates hydroxylation of gamma-L-Glu-GABA-S-BtrI.
  catalytic activity: 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2 = 4- (gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O (RHEA:53960)
  subunit: Homotetramer.

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