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PaperBLAST

PaperBLAST Hits for BRENDA::Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) (Arabidopsis thaliana) (374 a.a., MTMAANLARR...)

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Found 250 similar proteins in the literature:

IDH-V / Q945K7 NAD+-dependent isocitrate dehydrogenase catalytic subunit (EC 1.1.1.286) from Arabidopsis thaliana (see 3 papers)
IDH5_ARATH / Q945K7 Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; IDH-V; Isocitric dehydrogenase 5; NAD(+)-specific ICDH 5; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
NP_568113 isocitrate dehydrogenase V from Arabidopsis thaliana
AT5G03290 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
100% identity, 100% coverage

IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
AT3G09810 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
88% identity, 100% coverage

LOC103934973 isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial from Pyrus x bretschneideri
84% identity, 99% coverage

M1CHE3 3-isopropylmalate dehydrogenase, chloroplastic from Solanum tuberosum
83% identity, 99% coverage

B6TJM1 3-isopropylmalate dehydrogenase from Zea mays
81% identity, 98% coverage

P29696 3-isopropylmalate dehydrogenase, chloroplastic from Solanum tuberosum
83% identity, 93% coverage

Q9VWH4 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Drosophila melanogaster
61% identity, 93% coverage

NP_728257 isocitrate dehydrogenase 3a, isoform C from Drosophila melanogaster
62% identity, 93% coverage

Q55BI2 Isocitrate dehydrogenase [NAD] regulatory subunit A, mitochondrial from Dictyostelium discoideum
60% identity, 92% coverage

G3H0B5 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Cricetulus griseus
56% identity, 96% coverage

D2VQ70 Isocitrate dehydrogenase from Naegleria gruberi
62% identity, 89% coverage

NP_446090 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor from Rattus norvegicus
56% identity, 96% coverage

IDH3A_MOUSE / Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Mus musculus (Mouse) (see paper)
Q9D6R2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Mus musculus (see paper)
NP_083849 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor from Mus musculus
56% identity, 96% coverage

F1LNF7 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Rattus norvegicus
56% identity, 93% coverage

IDH3A_BOVIN / P41563 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitrate dehydrogenase subunits 3/4; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Bos taurus (Bovine) (see paper)
56% identity, 96% coverage

U3I2P1 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Anas platyrhynchos platyrhynchos
56% identity, 86% coverage

G1TA59 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Oryctolagus cuniculus
55% identity, 79% coverage

IDH3A_PIG / P56471 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Sus scrofa (Pig) (see paper)
55% identity, 96% coverage

IDH3A_RAT / Q99NA5 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Rattus norvegicus (Rat) (see paper)
Q99NA5 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rattus norvegicus (see paper)
56% identity, 96% coverage

IDH3A / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3A_HUMAN / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Homo sapiens (Human) (see 5 papers)
P50213 isocitrate dehydrogenase (NAD+) (subunit 2/2) (EC 1.1.1.41) from Homo sapiens (see paper)
55% identity, 96% coverage

Q53GF8 Isocitrate dehydrogenase [NAD] subunit, mitochondrial (Fragment) from Homo sapiens
55% identity, 96% coverage

6kdeA / P50213 Crystal structure of the alpha beta heterodimer of human idh3 in complex with ca(2+) (see paper)
59% identity, 87% coverage

Q28480 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (Fragment) from Macaca fascicularis
57% identity, 91% coverage

IDH3A_CAEEL / Q93714 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Caenorhabditis elegans (see paper)
NP_492330 putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Caenorhabditis elegans
57% identity, 92% coverage

A0A0D1E633 isocitrate dehydrogenase (NAD(+)) from Ustilago maydis (strain 521 / FGSC 9021)
58% identity, 85% coverage

EHS24_002540 NAD-dependent isocitrate dehydrogenase from Apiotrichum porosum
60% identity, 92% coverage

G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
58% identity, 94% coverage

Afu1g12800 isocitrate dehydrogenase, NAD-dependent from Aspergillus fumigatus Af293
58% identity, 86% coverage

IDH2_SCHPO / Q9USP8 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
55% identity, 92% coverage

RHTO_01290 isocitrate dehydrogenase (NAD+) from Rhodotorula toruloides NP11
57% identity, 94% coverage

idh2 / RF|NP_595203.1 isocitrate dehydrogenase (NAD+) subunit 2; EC 1.1.1.41 from Schizosaccharomyces pombe (see 2 papers)
SPBC902.05c isocitrate dehydrogenase (NAD+) subunit 2 from Schizosaccharomyces pombe
55% identity, 93% coverage

CNA04610 isocitrate dehydrogenase from Cryptococcus neoformans var. neoformans JEC21
60% identity, 87% coverage

CNAG_07363 isocitrate dehydrogenase, NAD-dependent from Cryptococcus neoformans var. grubii H99
60% identity, 87% coverage

TERG_07814 isocitrate dehydrogenase, NAD-dependent from Trichophyton rubrum CBS 118892
58% identity, 86% coverage

An08g05580 uncharacterized protein from Aspergillus niger
57% identity, 75% coverage

AO090012000629 No description from Aspergillus oryzae RIB40
57% identity, 86% coverage

PADG_02805 isocitrate dehydrogenase [NAD] subunit 2, mitochondrial from Paracoccidioides brasiliensis Pb18
C1G6K0 isocitrate dehydrogenase (NAD(+)) from Paracoccidioides brasiliensis (strain Pb18)
58% identity, 86% coverage

PAAG_07729 isocitrate dehydrogenase subunit 2 from Paracoccidioides lutzii Pb01
58% identity, 86% coverage

Q6CA33 isocitrate dehydrogenase (NAD(+)) from Yarrowia lipolytica (strain CLIB 122 / E 150)
56% identity, 88% coverage

CG32026 uncharacterized protein from Drosophila melanogaster
54% identity, 46% coverage

CLJU_c06630 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium ljungdahlii DSM 13528
56% identity, 88% coverage

CAETHG_2753 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium autoethanogenum DSM 10061
55% identity, 88% coverage

CAC0972 Isocitrate dehydrogenase from Clostridium acetobutylicum ATCC 824
CA_C0972 isocitrate dehydrogenase (NAD(+)) from Clostridium acetobutylicum ATCC 824
53% identity, 88% coverage

IDH2 / P28241 isocitrate dehydrogenase [NAD] β subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH2_YEAST / P28241 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P28241 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
YOR136W Idh2p from Saccharomyces cerevisiae
NP_014779 isocitrate dehydrogenase (NAD(+)) IDH2 from Saccharomyces cerevisiae S288C
54% identity, 90% coverage

Csac_0751 Isocitrate dehydrogenase (NAD(+)) from Caldicellulosiruptor saccharolyticus DSM 8903
52% identity, 88% coverage

Clocel_2469 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium cellulovorans 743B
50% identity, 88% coverage

Q6ZI55 NAD-dependent isocitrate dehydrogenase c2 from Oryza sativa subsp. japonica
52% identity, 88% coverage

LOC107804365 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial-like from Nicotiana tabacum
49% identity, 91% coverage

Sb04g024840 No description from Sorghum bicolor
52% identity, 89% coverage

AO090003000008 No description from Aspergillus oryzae RIB40
48% identity, 91% coverage

I1IB67 Isopropylmalate dehydrogenase-like domain-containing protein from Brachypodium distachyon
52% identity, 89% coverage

An18g06760 uncharacterized protein from Aspergillus niger
49% identity, 91% coverage

PAAG_00856 isocitrate dehydrogenase subunit 1 from Paracoccidioides lutzii Pb01
52% identity, 85% coverage

3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
53% identity, 90% coverage

I1IYV8 Isopropylmalate dehydrogenase-like domain-containing protein from Brachypodium distachyon
51% identity, 89% coverage

IDH1_ARATH / Q8LFC0 Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; IDH-I; Isocitric dehydrogenase 1; NAD(+)-specific ICDH 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LFC0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
NP_195252 IDH1 (ISOCITRATE DEHYDROGENASE 1); isocitrate dehydrogenase (NAD+)/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor from Arabidopsis thaliana
AT4G35260, NP_195252 isocitrate dehydrogenase 1 from Arabidopsis thaliana
51% identity, 89% coverage

LOC112172665 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Rosa chinensis
50% identity, 89% coverage

NCU00775 isocitrate dehydrogenase subunit 1 from Neurospora crassa OR74A
51% identity, 86% coverage

Q91VA7 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Mus musculus
NP_570954 isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform 1 from Mus musculus
46% identity, 96% coverage

CD0834 putative isocitrate/3-isopropylmalate dehydrogenase from Clostridium difficile 630
Q18A33 Isocitrate dehydrogenase NAD-dependent from Clostridioides difficile (strain 630)
53% identity, 88% coverage

SO1538 isocitrate dehydrogenase, NAD-dependent from Shewanella oneidensis MR-1
49% identity, 88% coverage

Q4WNH3 isocitrate dehydrogenase (NAD(+)) from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
47% identity, 82% coverage

LOC18035427 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Citrus x clementina
49% identity, 89% coverage

Gasu_48810 isocitrate dehydrogenase (NAD+) from Galdieria sulphuraria
47% identity, 82% coverage

EHS24_002733 isocitrate dehydrogenase (NAD(+)) idh1 from Apiotrichum porosum
52% identity, 86% coverage

RHTO_01289 isocitrate dehydrogenase (NAD+) from Rhodotorula toruloides NP11
48% identity, 95% coverage

LOC18037111 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Citrus x clementina
50% identity, 88% coverage

NP_001349681 isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform 2 from Mus musculus
45% identity, 97% coverage

CNAG_07851 isocitrate dehydrogenase, NAD-dependent from Cryptococcus neoformans var. grubii H99
50% identity, 87% coverage

Q58DM0 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Bos taurus
48% identity, 87% coverage

IDH3G / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3G_HUMAN / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Isocitric dehydrogenase subunit gamma; NAD(+)-specific ICDH subunit gamma from Homo sapiens (Human) (see 3 papers)
P51553 isocitrate dehydrogenase (NAD+) (subunit 1/3) (EC 1.1.1.41) from Homo sapiens (see 4 papers)
NP_004126 isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial isoform a precursor from Homo sapiens
49% identity, 84% coverage

T5A5Y2 isocitrate dehydrogenase (NAD(+)) from Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243)
52% identity, 87% coverage

Q58D96 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Bos taurus
50% identity, 85% coverage

IDH3_ARATH / O81796 Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; IDH-III; Isocitric dehydrogenase 3; NAD(+)-specific ICDH 3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O81796 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
NP_195290 isocitrate dehydrogenase III from Arabidopsis thaliana
AT4G35650 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
50% identity, 88% coverage

B7Z9J8 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Homo sapiens
61% identity, 67% coverage

P41565 Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial from Rattus norvegicus
49% identity, 84% coverage

G1APK2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
48% identity, 95% coverage

Q5XIJ3 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Rattus norvegicus
49% identity, 84% coverage

W5P8N8 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Ovis aries
O77784 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial from Bos taurus
50% identity, 85% coverage

5grfB / P51553 Crystal structure of the alpha gamma mutant (gamma-k151a) of human idh3 in complex with mg(2+), citrate and adp (see paper)
49% identity, 88% coverage

IDH-II / P93032 NAD+-dependent isocitrate dehydrogenase regulatory subunit (EC 1.1.1.286) from Arabidopsis thaliana (see paper)
IDH2_ARATH / P93032 Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; IDH-II; Isocitric dehydrogenase 2; NAD(+)-specific ICDH 2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P93032 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
AT2G17130 IDH2 (ISOCITRATE DEHYDROGENASE SUBUNIT 2); isocitrate dehydrogenase (NAD+)/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor from Arabidopsis thaliana
48% identity, 89% coverage

Q68FX0 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial from Rattus norvegicus
50% identity, 85% coverage

NP_001234366 isocitrate dehydrogenase [NAD] regulatory subunit 1 from Solanum lycopersicum
48% identity, 89% coverage

P70404 Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial from Mus musculus
NP_032349 isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial isoform 1 precursor from Mus musculus
49% identity, 84% coverage

M1BEG6 NAD-dependent isocitrate dehydrogenase from Solanum tuberosum
48% identity, 89% coverage

Q1G1K7 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Sus scrofa
50% identity, 85% coverage

IDH3B / O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3B_HUMAN / O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Isocitric dehydrogenase subunit beta; NAD(+)-specific ICDH subunit beta from Homo sapiens (Human) (see 3 papers)
O43837 isocitrate dehydrogenase (NAD+) (subunit 1/2) (EC 1.1.1.41) from Homo sapiens (see paper)
50% identity, 85% coverage

ABO_0296 isocitrate dehydrogenase from Alcanivorax borkumensis SK2
48% identity, 88% coverage

G3HSW9 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Cricetulus griseus
49% identity, 87% coverage

G3H450 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Cricetulus griseus
49% identity, 85% coverage

6kdyD / O43837 Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD. (see paper)
49% identity, 87% coverage

WP_010895014 isocitrate dehydrogenase from Xylella fastidiosa 9a5c
XF2596 isocitrate dehydrogenase from Xylella fastidiosa 9a5c
49% identity, 88% coverage

6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
47% identity, 88% coverage

DhcVS_392, GY50_0375 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi VS
48% identity, 83% coverage

DET0450 isocitrate dehydrogenase, putative from Dehalococcoides ethenogenes 195
48% identity, 83% coverage

IDH1 / P28834 isocitrate dehydrogenase [NAD] α subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH1_YEAST / P28834 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P28834 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
NP_014361 isocitrate dehydrogenase (NAD(+)) IDH1 from Saccharomyces cerevisiae S288C
YNL037C Idh1p from Saccharomyces cerevisiae
48% identity, 89% coverage

IDH1_SCHPO / O13696 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
idh1 / RF|NP_594397.1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1; EC 1.1.1.41 from Schizosaccharomyces pombe (see 3 papers)
SPAC11G7.03 isocitrate dehydrogenase (NAD+) subunit 1 Idh1 (PMID 10975257) from Schizosaccharomyces pombe
50% identity, 88% coverage

3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
48% identity, 89% coverage

NP_849963 isocitrate dehydrogenase subunit 2 from Arabidopsis thaliana
47% identity, 89% coverage

PAS_chr4_0580 Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase from Komagataella phaffii GS115
49% identity, 88% coverage

NP_777280 isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform b precursor from Homo sapiens
49% identity, 85% coverage

btf_415 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi BTF08
48% identity, 83% coverage

DehalGT_0391 Isocitrate dehydrogenase (NAD(+)) from Dehalococcoides sp. GT
cbdbA408 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi CBDB1
48% identity, 83% coverage

dcmb_461 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi DCMB5
48% identity, 83% coverage

Q684I8 Isocitrate dehydrogenase [NAD] subunit, mitochondrial (Fragment) from Mus musculus
51% identity, 80% coverage

XAUB_41080 isocitrate dehydrogenase from Xanthomonas citri pv. aurantifolii str. ICPB 11122
XAC1046 isocitrate dehydrogenase from Xanthomonas axonopodis pv. citri str. 306
49% identity, 88% coverage

A8J6V1 Isopropylmalate dehydrogenase-like domain-containing protein from Chlamydomonas reinhardtii
49% identity, 91% coverage

6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
48% identity, 88% coverage

HCAG_04093 isocitrate dehydrogenase subunit 1, mitochondrial precursor from Histoplasma mississippiense (nom. inval.)
53% identity, 76% coverage

ELEN_RS11715 isocitrate/isopropylmalate dehydrogenase family protein from Eggerthella lenta DSM 2243
47% identity, 87% coverage

APA386B_2558 isocitrate/isopropylmalate dehydrogenase family protein from Acetobacter pasteurianus 386B
47% identity, 89% coverage

IDHG2_MOUSE / Q8BPC6 Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial; Isocitric dehydrogenase subunit gamma 2; NAD(+)-specific ICDH subunit gamma 2 from Mus musculus (Mouse) (see paper)
43% identity, 86% coverage

NP_001398448 isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial isoform 7 from Mus musculus
51% identity, 74% coverage

AL01_06250 isocitrate/isopropylmalate dehydrogenase family protein from Bombella intestini
45% identity, 91% coverage

Q0QHL1 Isocitrate dehydrogenase (NAD+) 1 from Glossina morsitans morsitans
42% identity, 84% coverage

GOX1336 Isocitrate dehydrogenase [NADP] from Gluconobacter oxydans 621H
45% identity, 89% coverage

2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
44% identity, 66% coverage

P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
TTHA1535 isocitrate dehydrogenase from Thermus thermophilus HB8
44% identity, 66% coverage

TTC1172 No description from Thermus thermophilus HB27
44% identity, 66% coverage

Mal52_56040 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella dynata
42% identity, 84% coverage

CA54_25060 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella macrocystis
42% identity, 84% coverage

Pan258_54730 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella dynata
42% identity, 84% coverage

E9PF84 Isocitrate dehydrogenase [NAD] subunit, mitochondrial (Fragment) from Homo sapiens
54% identity, 66% coverage

Rfer_2380 Isocitrate dehydrogenase (NAD+) from Rhodoferax ferrireducens DSM 15236
47% identity, 90% coverage

Rfer_2411 Isocitrate dehydrogenase (NAD+) from Rhodoferax ferrireducens DSM 15236
47% identity, 90% coverage

Mal4_26830 isocitrate/isopropylmalate dehydrogenase family protein from Maioricimonas rarisocia
42% identity, 84% coverage

Mal48_24210 isocitrate/isopropylmalate dehydrogenase family protein from Thalassoglobus polymorphus
42% identity, 84% coverage

B4GFZ8 GL21529 from Drosophila persimilis
42% identity, 81% coverage

E0VSN4 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Pediculus humanus subsp. corporis
44% identity, 84% coverage

Marky_1533 isocitrate/isopropylmalate dehydrogenase family protein from Marinithermus hydrothermalis DSM 14884
45% identity, 87% coverage

LIC13328 isocitrate dehydrogenase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Q72M63 Isocitrate dehydrogenase [NADP] from Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
44% identity, 66% coverage

Ocepr_1387 No description from Oceanithermus profundus 506, DSM 14977
44% identity, 87% coverage

TSC_c20650 homoisocitrate dehydrogenase from Thermus scotoductus SA-01
44% identity, 87% coverage

AM1131 isocitrate dehydrogenase from Anaplasma marginale str. St. Maries
42% identity, 69% coverage

Pyrde_1536 isocitrate/isopropylmalate dehydrogenase family protein from Pyrodictium delaneyi
41% identity, 88% coverage

Mrub_2738 3-isopropylmalate dehydrogenase from Meiothermus ruber DSM 1279
43% identity, 87% coverage

Q4JB37 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfolobus acidocaldarius (see paper)
Saci_0600 3-isopropylmalate dehydrogenase from Sulfolobus acidocaldarius DSM 639
42% identity, 86% coverage

4y1pB / Q4JB37 Crystal structure of 3-isopropylmalate dehydrogenase (saci_0600) from sulfolobus acidocaldarius complex with 3-isopropylmalate and mg2+ (see paper)
42% identity, 86% coverage

MMP0880 2-oxosuberate synthase, last step from Methanococcus maripaludis S2
43% identity, 87% coverage

hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
TTHA1378 homoisocitrate dehydrogenase from Thermus thermophilus HB8
TTC1012 No description from Thermus thermophilus HB27
43% identity, 87% coverage

3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
43% identity, 87% coverage

LEU3_SULTO / P50455 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
P50455 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfurisphaera tokodaii (see 3 papers)
40% identity, 89% coverage

Trad_2841 isocitrate/isopropylmalate dehydrogenase family protein from Truepera radiovictrix DSM 17093
42% identity, 88% coverage

Mmah_0582 isocitrate dehydrogenase (NADP) from Methanohalophilus mahii DSM 5219
40% identity, 88% coverage

Deima_1545 isocitrate/isopropylmalate dehydrogenase family protein from Deinococcus maricopensis DSM 21211
40% identity, 87% coverage

CG3483 uncharacterized protein from Drosophila melanogaster
36% identity, 89% coverage

MMP0539 3-isopropylmalate dehydrogenase from Methanococcus maripaludis S2
39% identity, 87% coverage

MA4265 isocitrate/isopropylmalate dehydrogenase family protein from Methanosarcina acetivorans C2A
40% identity, 88% coverage

MJ0720 / Q58130 3-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
LEU3_METJA / Q58130 3-isopropylmalate/3-methylmalate dehydrogenase; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.85; EC 1.1.1.n5; EC 1.1.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
MJ0720 3-isopropylmalate dehydrogenase 1 (leuB1) from Methanocaldococcus jannaschii DSM 2661
40% identity, 87% coverage

Dgeo_1458 3-isopropylmalate dehydrogenase from Deinococcus geothermalis DSM 11300
38% identity, 87% coverage

MCP_0437 isocitrate/isopropylmalate dehydrogenase family protein from Methanocella paludicola SANAE
39% identity, 87% coverage

hdh / BAD06515.1 homoisocitrate dehydrogenase, partial from Deinococcus radiodurans (see paper)
DR1674, DR_1674 isocitrate dehydrogenase, putative from Deinococcus radiodurans R1
39% identity, 87% coverage

Q5A9D9 Homoisocitrate dehydrogenase from Candida albicans (strain SC5314 / ATCC MYA-2876)
38% identity, 91% coverage

llmg_0637 isocitrate dehydrogenase from Lactococcus lactis subsp. cremoris MG1363
35% identity, 79% coverage

LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate from Saccharomyces cerevisiae
NP_012172 homoisocitrate dehydrogenase from Saccharomyces cerevisiae S288C
37% identity, 93% coverage

GAH_01703 isocitrate dehydrogenase (NADP(+)) from Geoglobus ahangari
37% identity, 79% coverage

Deide_09240 putative 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase) (IMDH) from Deinococcus deserti VCD115
38% identity, 87% coverage

Mmah_0129 3-isopropylmalate dehydrogenase from Methanohalophilus mahii DSM 5219
42% identity, 85% coverage

LYS12_SCHPO / O14104 Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.87 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
NP_594004 homoisocitrate dehydrogenase Lys12 from Schizosaccharomyces pombe
SPAC31G5.04 homoisocitrate dehydrogenase from Schizosaccharomyces pombe
37% identity, 89% coverage

3ty3A / O14104 Crystal structure of homoisocitrate dehydrogenase from schizosaccharomyces pombe bound to glycyl-glycyl-glycine (see paper)
37% identity, 87% coverage

Q9HNZ7 isocitrate dehydrogenase (NADP(+)) from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
35% identity, 79% coverage

CND03850 isocitrate dehydrogenase from Cryptococcus neoformans var. neoformans JEC21
38% identity, 87% coverage

Q8U488 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Pyrococcus furiosus (see 2 papers)
PF0202 isocitrate dehydrogenase from Pyrococcus furiosus DSM 3638
38% identity, 83% coverage

NCU02954 homoisocitrate dehydrogenase from Neurospora crassa OR74A
38% identity, 81% coverage

Q9HLV8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermoplasma acidophilum (see paper)
37% identity, 76% coverage

IDH_ARCFU / O29610 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 2 papers)
2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
AF_0647 isocitrate dehydrogenase (NADP(+)) from Archaeoglobus fulgidus DSM 4304
35% identity, 79% coverage

PF0940 3-isopropylmalate dehydrogenase 2 from Pyrococcus furiosus DSM 3638
37% identity, 89% coverage

SSO2182 Isocitrate dehydrogenase, probable (idh) from Sulfolobus solfataricus P2
35% identity, 78% coverage

Kole_1227 isocitrate dehydrogenase (NADP(+)) from Kosmotoga olearia TBF 19.5.1
Kole_1227 Isocitrate dehydrogenase (NADP(+)) from Thermotogales bacterium TBF 19.5.1
35% identity, 81% coverage

aksF / Q58991 NAD-dependent threo-isocitrate dehydrogenase (EC 1.1.1.87) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AKSF_METJA / Q58991 Homoisocitrate dehydrogenase; HICDH; Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase; Isohomocitrate dehydrogenase; IHDH; NAD-dependent threo-isohomocitrate dehydrogenase; EC 1.1.1.87; EC 1.1.1.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58991 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii (see paper)
38% identity, 87% coverage

icdh / CAC80860.2 NADP-isocitrate dehydrogenase from Haloferax volcanii (see paper)
33% identity, 77% coverage

BBA_01606 isocitrate/isopropylmalate dehydrogenase from Beauveria bassiana ARSEF 2860
36% identity, 87% coverage

MJ1596 3-isopropylmalate dehydrogenase 2 (leuB2) from Methanocaldococcus jannaschii DSM 2661
37% identity, 87% coverage

lysB putative homoisocitrate dehydrogenase from Emericella nidulans (see paper)
37% identity, 87% coverage

AFUA_6G07390 isocitrate dehydrogenase LysB from Aspergillus fumigatus Af293
35% identity, 87% coverage

O67480 Isocitrate dehydrogenase [NADP] from Aquifex aeolicus (strain VF5)
aq_1512 isocitrate dehydrogenase from Aquifex aeolicus VF5
37% identity, 70% coverage

IDH_HALVD / D4GU92 Isocitrate dehydrogenase [NADP]; ICDH; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
HVO_2588 isocitrate dehydrogenase (NADP+) from Haloferax volcanii DS2
33% identity, 77% coverage

An15g02490 uncharacterized protein from Aspergillus niger
37% identity, 87% coverage

LLKF_1261 3-isopropylmalate dehydrogenase from Lactococcus lactis subsp. lactis KF147
37% identity, 86% coverage

Q5JFV8 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Thermococcus kodakarensis (see paper)
TK0280 homoisocitrate dehydrogenase from Thermococcus kodakaraensis KOD1
38% identity, 87% coverage

5hn4A / Q5JFV8 Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and homoisocitrate (see paper)
38% identity, 87% coverage

Q9YE81 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Aeropyrum pernix (see 4 papers)
34% identity, 77% coverage

1tyoA / Q9YE81 Isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in complex with etheno-NADP (see paper)
34% identity, 78% coverage

WP_010980246 NADP-dependent isocitrate dehydrogenase from Sulfurisphaera tokodaii str. 7
ST2166 409aa long hypothetical NADP-dependent isocitrate dehydrogenase from Sulfolobus tokodaii str. 7
34% identity, 74% coverage

SRU_1973 isocitrate dehydrogenase, NADP-dependent from Salinibacter ruber DSM 13855
35% identity, 75% coverage

icd / Q76LM6 oxalosuccinate reductase subunit from Hydrogenobacter thermophilus (see 3 papers)
36% identity, 77% coverage

IDH_CALNO / P96318 Isocitrate dehydrogenase [NADP]; ICDH; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Caldococcus noboribetus (see paper)
P96318 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Caldococcus noboribetus (see 2 papers)
36% identity, 76% coverage

VDAG_01116 homoisocitrate dehydrogenase from Verticillium dahliae VdLs.17
37% identity, 87% coverage

LEU3_HALVD / D4GYE8 3-isopropylmalate dehydrogenase; EC 1.1.1.85 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
HVO_1502 3-isopropylmalate dehydrogenase from Haloferax volcanii DS2
40% identity, 87% coverage

lpg2683 DlpA protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Q48806 Protein DlpA from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
32% identity, 54% coverage

Q72EU1 isocitrate dehydrogenase (NADP(+)) from Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough)
34% identity, 82% coverage

icd / Q5UXA4 isocitrate dehydrogenase, NADP (EC 1.1.1.42) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see 4 papers)
34% identity, 77% coverage

Q9RU54 Isocitrate dehydrogenase [NADP] from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
DR1540, DR_1540 isocitrate dehydrogenase from Deinococcus radiodurans R1
34% identity, 75% coverage

YP_092619 Icd from Bacillus licheniformis DSM 13
31% identity, 76% coverage

SSU1040 isocitrate dehydrogenase [NADP] from Streptococcus suis P1/7
35% identity, 82% coverage

LAF_0939 isocitrate dehydrogenase from Lactobacillus fermentum IFO 3956
LAF_0939 NADP-dependent isocitrate dehydrogenase from Limosilactobacillus fermentum IFO 3956
32% identity, 79% coverage

T303_07275 NADP-dependent isocitrate dehydrogenase from Streptococcus thermophilus ASCC 1275
36% identity, 79% coverage

Micr_00902 NADP-dependent isocitrate dehydrogenase from Candidatus Micrarchaeum sp.
32% identity, 81% coverage

Q6GG12 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain MRSA252)
33% identity, 71% coverage

SAV1694 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus Mu50
P99167 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain N315)
Q2FXN4 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain NCTC 8325 / PS 47)
SA1517 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus N315
SAOUHSC_01801 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus NCTC 8325
SAUSA300_1640 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus USA300_FPR3757
SACOL1741 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus COL
33% identity, 71% coverage

GYA98_RS12235 NADP-dependent isocitrate dehydrogenase from Bacillus velezensis
33% identity, 70% coverage

SAS1622 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus MSSA476
33% identity, 71% coverage

PAAG_06387 homoisocitrate dehydrogenase from Paracoccidioides lutzii Pb01
34% identity, 87% coverage

BF638R_3568 NADP-dependent isocitrate dehydrogenase from Bacteroides fragilis 638R
34% identity, 83% coverage

IDH_BACSU / P39126 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Bacillus subtilis (strain 168) (see 2 papers)
icd / GB|CAB14873.1 isocitrate dehydrogenase; EC 1.1.1.42 from Bacillus subtilis (see 2 papers)
NP_390791 isocitrate dehydrogenase from Bacillus subtilis subsp. subtilis str. 168
33% identity, 70% coverage

SAPIG1748 NADP-dependent isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus ST398
33% identity, 71% coverage

ABD05_RS18190 tartrate dehydrogenase from Burkholderia pyrrocinia
32% identity, 87% coverage

F4RL47 Isopropylmalate dehydrogenase-like domain-containing protein from Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7)
35% identity, 87% coverage

SGO_1611 Isocitrate dehydrogenase from Streptococcus gordonii str. Challis substr. CH1
34% identity, 81% coverage

IHV18_09900 3-isopropylmalate dehydrogenase from Bifidobacterium breve
36% identity, 81% coverage

Q8CNX4 Isocitrate dehydrogenase [NADP] from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HNL1 Isocitrate dehydrogenase [NADP] from Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
33% identity, 71% coverage

Dgeo_1166 isocitrate/isopropylmalate dehydrogenase from Deinococcus geothermalis DSM 11300
33% identity, 77% coverage

Tneu_0698 isocitrate dehydrogenase, NADP-dependent from Thermoproteus neutrophilus V24Sta
34% identity, 70% coverage

HICDH_PYRHO / O59394 Isocitrate/homoisocitrate dehydrogenase; HICDH; Beta-decarboxylating dehydrogenase; EC 1.1.1.286 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
PH1722 3-isopropylmalate dehydrogenase from Pyrococcus horikoshii OT3
37% identity, 87% coverage

Q4J6C9 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Sulfolobus acidocaldarius (see paper)
Saci_2375 isocitrate dehydrogenase from Sulfolobus acidocaldarius DSM 639
33% identity, 73% coverage

M0P24_RS06755 3-isopropylmalate dehydrogenase from Streptococcus pasteurianus
36% identity, 87% coverage

MAB_4419 Tartrate dehydrogenase from Mycobacterium abscessus ATCC 19977
35% identity, 87% coverage

Q59940 Isocitrate dehydrogenase [NADP] from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
32% identity, 82% coverage

cg1453 3-isopropylmalate dehydrogenase from Corynebacterium glutamicum ATCC 13032
36% identity, 80% coverage

PSPPH_2159 dehydrogenase, isocitrate/isopropylmalate family from Pseudomonas syringae pv. phaseolicola 1448A
34% identity, 82% coverage

T303_06875 3-isopropylmalate dehydrogenase from Streptococcus thermophilus ASCC 1275
36% identity, 87% coverage

Ssal_01275 3-isopropylmalate dehydrogenase from Streptococcus salivarius 57.I
37% identity, 87% coverage

BBMN68_984 3-isopropylmalate dehydrogenase from Bifidobacterium longum subsp. longum BBMN68
35% identity, 81% coverage

2e5mA / Q96YK6 Crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain 7 (see paper)
33% identity, 75% coverage

SAV2058 3-isopropylmalate dehydrogenase from Staphylococcus aureus subsp. aureus Mu50
SA1863 3-isopropylmalate dehydrogenase from Staphylococcus aureus subsp. aureus N315
36% identity, 87% coverage

MS2370 NADP-dependent isocitrate dehydrogenase from [Mannheimia] succiniciproducens MBEL55E
MS2370 Icd protein from Mannheimia succiniciproducens MBEL55E
33% identity, 78% coverage

Q1GZD1 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Methylobacillus flagellatus (see paper)
34% identity, 78% coverage

Q1XIQ8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Colwellia psychrerythraea (see paper)
33% identity, 78% coverage

P24098 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus aquaticus (see paper)
35% identity, 88% coverage

P61494 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 2 papers)
36% identity, 89% coverage

SXYL_01173 NADP-dependent isocitrate dehydrogenase from Staphylococcus xylosus
33% identity, 71% coverage

AT1G32480 oxidoreductase/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor from Arabidopsis thaliana
42% identity, 59% coverage

VAS14_05433 NADP-dependent isocitrate dehydrogenase from Photobacterium angustum S14
34% identity, 70% coverage

AFUA_1G04150 tartrate dehydrogenase, putative from Aspergillus fumigatus Af293
34% identity, 89% coverage

CNI00890 tartrate dehydrogenase from Cryptococcus neoformans var. neoformans JEC21
33% identity, 87% coverage

BC1401 3-isopropylmalate dehydrogenase from Bacillus cereus ATCC 14579
35% identity, 87% coverage

CBU_1200 isocitrate dehydrogenase from Coxiella burnetii RSA 493
32% identity, 82% coverage

BAS1312 3-isopropylmalate dehydrogenase from Bacillus anthracis str. Sterne
36% identity, 87% coverage

IDH_COXBU / Q9ZH99 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see 2 papers)
32% identity, 82% coverage

B4602_RS10785 3-isopropylmalate dehydrogenase from Staphylococcus aureus
36% identity, 87% coverage

Q8GAX0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Acidithiobacillus thiooxidans (see paper)
31% identity, 75% coverage

2d4vA / Q8GAX0 Crystal structure of NAD dependent isocitrate dehydrogenase from acidithiobacillus thiooxidans (see paper)
31% identity, 75% coverage

P61495 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see paper)
35% identity, 89% coverage

LEU3_THET8 / Q5SIY4 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 4 papers)
Q5SIY4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 12 papers)
35% identity, 89% coverage

DIP1105 3-isopropylmalate dehydrogenase from Corynebacterium diphtheriae NCTC 13129
34% identity, 82% coverage

ACIAD1190 isocitrate dehydrogenase from Acinetobacter sp. ADP1
32% identity, 74% coverage

N007_05885 NADP-dependent isocitrate dehydrogenase from Alicyclobacillus acidoterrestris ATCC 49025
32% identity, 75% coverage

SACOL2047 3-isopropylmalate dehydrogenase from Staphylococcus aureus subsp. aureus COL
SAUSA300_2011 3-isopropylmalate dehydrogenase from Staphylococcus aureus subsp. aureus USA300_FPR3757
NWMN_1964 3-isopropylmalate dehydrogenase from Staphylococcus aureus subsp. aureus str. Newman
36% identity, 87% coverage

SCO5522 3-isopropylmalate dehydrogenase from Streptomyces coelicolor A3(2)
34% identity, 81% coverage

E9B494 Isocitrate dehydrogenase [NADP] from Leishmania mexicana (strain MHOM/GT/2001/U1103)
32% identity, 76% coverage

New Search

For advice on how to use these tools together, see Interactive tools for functional annotation of bacterial genomes.

Statistics

The PaperBLAST database links 784,739 different protein sequences to 1,253,012 scientific articles. Searches against EuropePMC were last performed on November 25 2024.

How It Works

PaperBLAST builds a database of protein sequences that are linked to scientific articles. These links come from automated text searches against the articles in EuropePMC and from manually-curated information from GeneRIF, UniProtKB/Swiss-Prot, BRENDA, CAZy (as made available by dbCAN), BioLiP, CharProtDB, MetaCyc, EcoCyc, TCDB, REBASE, the Fitness Browser, and a subset of the European Nucleotide Archive with the /experiment tag. Given this database and a protein sequence query, PaperBLAST uses protein-protein BLAST to find similar sequences with E < 0.001.

To build the database, we query EuropePMC with locus tags, with RefSeq protein identifiers, and with UniProt accessions. We obtain the locus tags from RefSeq or from MicrobesOnline. We use queries of the form "locus_tag AND genus_name" to try to ensure that the paper is actually discussing that gene. Because EuropePMC indexes most recent biomedical papers, even if they are not open access, some of the links may be to papers that you cannot read or that our computers cannot read. We query each of these identifiers that appears in the open access part of EuropePMC, as well as every locus tag that appears in the 500 most-referenced genomes, so that a gene may appear in the PaperBLAST results even though none of the papers that mention it are open access. We also incorporate text-mined links from EuropePMC that link open access articles to UniProt or RefSeq identifiers. (This yields some additional links because EuropePMC uses different heuristics for their text mining than we do.)

For every article that mentions a locus tag, a RefSeq protein identifier, or a UniProt accession, we try to select one or two snippets of text that refer to the protein. If we cannot get access to the full text, we try to select a snippet from the abstract, but unfortunately, unique identifiers such as locus tags are rarely provided in abstracts.

PaperBLAST also incorporates manually-curated protein functions:

Except for GeneRIF and ENA, the curated entries include a short curated description of the protein's function. For entries from BioLiP, the protein's function may not be known beyond binding to the ligand. Many of these entries also link to articles in PubMed.

For more information see the PaperBLAST paper (mSystems 2017) or the code. You can download PaperBLAST's database here.

Changes to PaperBLAST since the paper was written:

Many of these changes are described in Interactive tools for functional annotation of bacterial genomes.

Secrets

PaperBLAST cannot provide snippets for many of the papers that are published in non-open-access journals. This limitation applies even if the paper is marked as "free" on the publisher's web site and is available in PubmedCentral or EuropePMC. If a journal that you publish in is marked as "secret," please consider publishing elsewhere.

Omissions from the PaperBLAST Database

Many important articles are missing from PaperBLAST, either because the article's full text is not in EuropePMC (as for many older articles), or because the paper does not mention a protein identifier such as a locus tag, or because of PaperBLAST's heuristics. If you notice an article that characterizes a protein's function but is missing from PaperBLAST, please notify the curators at UniProt or add an entry to GeneRIF. Entries in either of these databases will eventually be incorporated into PaperBLAST. Note that to add an entry to UniProt, you will need to find the UniProt identifier for the protein. If the protein is not already in UniProt, you can ask them to create an entry. To add an entry to GeneRIF, you will need an NCBI Gene identifier, but unfortunately many prokaryotic proteins in RefSeq do not have corresponding Gene identifers.

References

PaperBLAST: Text-mining papers for information about homologs.
M. N. Price and A. P. Arkin (2017). mSystems, 10.1128/mSystems.00039-17.

Europe PMC in 2017.
M. Levchenko et al (2017). Nucleic Acids Research, 10.1093/nar/gkx1005.

Gene indexing: characterization and analysis of NLM's GeneRIFs.
J. A. Mitchell et al (2003). AMIA Annu Symp Proc 2003:460-464.

UniProt: the universal protein knowledgebase.
The UniProt Consortium (2016). Nucleic Acids Research, 10.1093/nar/gkw1099.

BRENDA in 2017: new perspectives and new tools in BRENDA.
S. Placzek et al (2017). Nucleic Acids Research, 10.1093/nar/gkw952.

The EcoCyc database: reflecting new knowledge about Escherichia coli K-12.
I. M. Keeseler et al (2016). Nucleic Acids Research, 10.1093/nar/gkw1003.

The MetaCyc database of metabolic pathways and enzymes.
R. Caspi et al (2018). Nucleic Acids Research, 10.1093/nar/gkx935.

CharProtDB: a database of experimentally characterized protein annotations.
R. Madupu et al (2012). Nucleic Acids Research, 10.1093/nar/gkr1133.

The carbohydrate-active enzymes database (CAZy) in 2013.
V. Lombard et al (2014). Nucleic Acids Research, 10.1093/nar/gkt1178.

The Transporter Classification Database (TCDB): recent advances
M. H. Saier, Jr. et al (2016). Nucleic Acids Research, 10.1093/nar/gkv1103.

REBASE - a database for DNA restriction and modification: enzymes, genes and genomes.
R. J. Roberts et al (2015). Nucleic Acids Research, 10.1093/nar/gku1046.

Deep annotation of protein function across diverse bacteria from mutant phenotypes.
M. N. Price et al (2016). bioRxiv, 10.1101/072470.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory